CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = T256S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2256T256ST436SnonsynAcaTca70330.4714291571-1573
ORF1ab/nsp2256T256ST436SnonsynAcATcC70330.4714291571-1573
ORF1ab/nsp2256T256ST436SnonsynAcATcT7020.02857141571-1573
ORF1ab/nsp2256T256ST436SnonsynaCAaGC7010.01428571571-1573
ORF1ab/nsp2256T256ST436SnonsynAcATcG7010.01428571571-1573

Details of the mutation T256S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2256T256SAcATcC3370All0.000006
ORF1ab/nsp2256T256SAcaTca3370All0.000006
ORF1ab/nsp2256T256SAcATcT270All0
ORF1ab/nsp2256T256SAcATcG170All0
ORF1ab/nsp2256T256SaCAaGC170All0
ORF1ab/nsp2256T256SAcATcC1324P.10.000205
ORF1ab/nsp2256T256SAcaTca1024P.10.000158
ORF1ab/nsp2256T256SAcATcT124P.10.000016
ORF1ab/nsp2256T256SAcATcC915P.20.00168
ORF1ab/nsp2256T256SAcaTca515P.20.000933
ORF1ab/nsp2256T256SAcATcT115P.20.000187
ORF1ab/nsp2256T256SAcaTca380.166667
ORF1ab/nsp2256T256SAcATcC380.166667
ORF1ab/nsp2256T256SaCAaGC180.055556
ORF1ab/nsp2256T256SAcATcG180.055556
ORF1ab/nsp2256T256SAcaTca46B.10.000037
ORF1ab/nsp2256T256SAcATcC26B.10.000018
ORF1ab/nsp2256T256SAcaTca24P.70.008734
ORF1ab/nsp2256T256SAcATcC24P.70.008734
ORF1ab/nsp2256T256SAcaTca12AY.99.20.000092
ORF1ab/nsp2256T256SAcATcC12AY.99.20.000092
ORF1ab/nsp2256T256SAcATcC12B.1.1.280.000311
ORF1ab/nsp2256T256SAcaTca12B.1.1.280.000311
ORF1ab/nsp2256T256SAcaTca22B.1.3510.000059
ORF1ab/nsp2256T256SAcATcC12P.1.20.001156
ORF1ab/nsp2256T256SAcaTca12P.1.20.001156
ORF1ab/nsp2256T256SAcaTca11AY.580.000907
ORF1ab/nsp2256T256SAcaTca11B.1.1.70.000001
ORF1ab/nsp2256T256SAcaTca11B.1.2210.000071
ORF1ab/nsp2256T256SAcaTca11B.1.5260.000024
ORF1ab/nsp2256T256SAcATcC11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.