CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = T166T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2166T166TT346TsynacTacA13556990.5158671301-1303
ORF1ab/nsp2166T166TT346TsynacTacC13553750.2767531301-1303
ORF1ab/nsp2166T166TT346TsynacTacG13552810.207381301-1303

Details of the mutation T166T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2166T166TacTacA6991355All0.000134
ORF1ab/nsp2166T166TacTacC3751355All0.000072
ORF1ab/nsp2166T166TacTacG2811355All0.000054
ORF1ab/nsp2166T166TacTacA411444B.1.1.70.000368
ORF1ab/nsp2166T166TacTacC20444B.1.1.70.000018
ORF1ab/nsp2166T166TacTacG13444B.1.1.70.000012
ORF1ab/nsp2166T166TacTacG136291AY.40.000212
ORF1ab/nsp2166T166TacTacC129291AY.40.000201
ORF1ab/nsp2166T166TacTacA26291AY.40.00004
ORF1ab/nsp2166T166TacTacA137145B.10.001255
ORF1ab/nsp2166T166TacTacC7145B.10.000064
ORF1ab/nsp2166T166TacTacG1145B.10.000009
ORF1ab/nsp2166T166TacTacC8181B.1.1.5131
ORF1ab/nsp2166T166TacTacC2650B.1.617.20.000098
ORF1ab/nsp2166T166TacTacG2050B.1.617.20.000075
ORF1ab/nsp2166T166TacTacA450B.1.617.20.000015
ORF1ab/nsp2166T166TacTacA4646B.1.1.5190.001827
ORF1ab/nsp2166T166TacTacG2732AY.430.00012
ORF1ab/nsp2166T166TacTacC432AY.430.000018
ORF1ab/nsp2166T166TacTacA132AY.430.000004
ORF1ab/nsp2166T166TacTacC2426B.1.20.000211
ORF1ab/nsp2166T166TacTacA226B.1.20.000018
ORF1ab/nsp2166T166TacTacC1316B.1.1770.000171
ORF1ab/nsp2166T166TacTacG316B.1.1770.00004
ORF1ab/nsp2166T166TacTacC715AY.440.000043
ORF1ab/nsp2166T166TacTacA715AY.440.000043
ORF1ab/nsp2166T166TacTacG115AY.440.000006
ORF1ab/nsp2166T166TacTacG1414AY.4.20.000304
ORF1ab/nsp2166T166TacTacA711AY.1030.000043
ORF1ab/nsp2166T166TacTacC411AY.1030.000025
ORF1ab/nsp2166T166TacTacG911AY.50.000186
ORF1ab/nsp2166T166TacTacA211AY.50.000041
ORF1ab/nsp2166T166TacTacC79AY.99.20.000645
ORF1ab/nsp2166T166TacTacA29AY.99.20.000184
ORF1ab/nsp2166T166TacTacC77AY.250.000042
ORF1ab/nsp2166T166TacTacG77AY.60.000288
ORF1ab/nsp2166T166TacTacG77B.1.177.830.01037
ORF1ab/nsp2166T166TacTacA67B.1.5260.000141
ORF1ab/nsp2166T166TacTacC17B.1.5260.000024
ORF1ab/nsp2166T166TacTacG45AY.200.000155
ORF1ab/nsp2166T166TacTacA15AY.200.000039
ORF1ab/nsp2166T166TacTacC55AY.290.000079
ORF1ab/nsp2166T166TacTacA55B.1.177.40.001055
ORF1ab/nsp2166T166TacTacC44AY.280.007561
ORF1ab/nsp2166T166TacTacG44AY.7.10.000451
ORF1ab/nsp2166T166TacTacC34AY.750.000168
ORF1ab/nsp2166T166TacTacG14AY.750.000056
ORF1ab/nsp2166T166TacTacA44B.1.10.000073
ORF1ab/nsp2166T166TacTacG33AY.1110.000549
ORF1ab/nsp2166T166TacTacG23AY.1200.000074
ORF1ab/nsp2166T166TacTacC13AY.1200.000037
ORF1ab/nsp2166T166TacTacA33AY.370.000948
ORF1ab/nsp2166T166TacTacG33AY.4.2.10.000447
ORF1ab/nsp2166T166TacTacA23AY.460.000208
ORF1ab/nsp2166T166TacTacG13AY.460.000104
ORF1ab/nsp2166T166TacTacG33AY.90.000203
ORF1ab/nsp2166T166TacTacG33AY.9.20.00011
ORF1ab/nsp2166T166TacTacA33B.1.6280.001057
ORF1ab/nsp2166T166TacTacA33C.370.000348
ORF1ab/nsp2166T166TacTacC23P.20.000373
ORF1ab/nsp2166T166TacTacG13P.20.000187
ORF1ab/nsp2166T166TacTacC22AY.1130.000285
ORF1ab/nsp2166T166TacTacC22AY.1180.000125
ORF1ab/nsp2166T166TacTacG22AY.120.2.10.000997
ORF1ab/nsp2166T166TacTacA22AY.260.000057
ORF1ab/nsp2166T166TacTacC22AY.270.000129
ORF1ab/nsp2166T166TacTacG22AY.4.40.000818
ORF1ab/nsp2166T166TacTacA12AY.4.50.000107
ORF1ab/nsp2166T166TacTacG12AY.4.50.000107
ORF1ab/nsp2166T166TacTacA22AY.420.00008
ORF1ab/nsp2166T166TacTacC12AY.450.000122
ORF1ab/nsp2166T166TacTacA12AY.450.000122
ORF1ab/nsp2166T166TacTacG22AY.46.60.000144
ORF1ab/nsp2166T166TacTacC22AY.470.000062
ORF1ab/nsp2166T166TacTacC22AY.75.10.000361
ORF1ab/nsp2166T166TacTacC22AY.880.001768
ORF1ab/nsp2166T166TacTacA22AY.9.10.000167
ORF1ab/nsp2166T166TacTacA22AY.910.001461
ORF1ab/nsp2166T166TacTacC22B.1.5070.022472
ORF1ab/nsp2166T166TacTacA12B.1.6210.000089
ORF1ab/nsp2166T166TacTacC12B.1.6210.000089
ORF1ab/nsp2166T166TacTacC12P.10.000016
ORF1ab/nsp2166T166TacTacA12P.10.000016
ORF1ab/nsp2166T166TacTacC11AY.1000.000046
ORF1ab/nsp2166T166TacTacC11AY.1050.000643
ORF1ab/nsp2166T166TacTacC11AY.16.10.00047
ORF1ab/nsp2166T166TacTacA11AY.240.000431
ORF1ab/nsp2166T166TacTacA11AY.3.10.000085
ORF1ab/nsp2166T166TacTacG11AY.360.000148
ORF1ab/nsp2166T166TacTacA11AY.390.000025
ORF1ab/nsp2166T166TacTacC11AY.39.10.00004
ORF1ab/nsp2166T166TacTacG11AY.410.000294
ORF1ab/nsp2166T166TacTacG11AY.70.000196
ORF1ab/nsp2166T166TacTacG11AY.900.000684
ORF1ab/nsp2166T166TacTacA11AY.930.000273
ORF1ab/nsp2166T166TacTacA11B0.000128
ORF1ab/nsp2166T166TacTacA11B.1.1.1570.000913
ORF1ab/nsp2166T166TacTacC11B.1.1.2160.00089
ORF1ab/nsp2166T166TacTacA11B.1.1.3170.000412
ORF1ab/nsp2166T166TacTacG11B.1.1.390.00051
ORF1ab/nsp2166T166TacTacC11B.1.110.30.000718
ORF1ab/nsp2166T166TacTacC11B.1.1600.000031
ORF1ab/nsp2166T166TacTacG11B.1.177.440.000519
ORF1ab/nsp2166T166TacTacC11B.1.177.540.000606
ORF1ab/nsp2166T166TacTacA11B.1.177.60.000977
ORF1ab/nsp2166T166TacTacC11B.1.177.810.000189
ORF1ab/nsp2166T166TacTacG11B.1.177.840.006667
ORF1ab/nsp2166T166TacTacG11B.1.2210.000071
ORF1ab/nsp2166T166TacTacA11B.1.2430.00007
ORF1ab/nsp2166T166TacTacA11B.1.258.170.000104
ORF1ab/nsp2166T166TacTacC11B.1.2810.021739
ORF1ab/nsp2166T166TacTacG11B.1.3320.003497
ORF1ab/nsp2166T166TacTacG11B.1.3510.00003
ORF1ab/nsp2166T166TacTacA11B.1.466.20.000391
ORF1ab/nsp2166T166TacTacG11B.1.5680.001111
ORF1ab/nsp2166T166TacTacC11B.1.5960.000087
ORF1ab/nsp2166T166TacTacA11B.1.617.10.000129
ORF1ab/nsp2166T166TacTacC11L.10.001905
ORF1ab/nsp2166T166TacTacA11P.1.120.000484
ORF1ab/nsp2166T166TacTacC11P.1.170.000162
ORF1ab/nsp2166T166TacTacA11P.1.70.000319
ORF1ab/nsp2166T166TacTacA11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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