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CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = S325F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2325S325FS505FnonsyntCctTc1064106411778-1780

Details of the mutation S325F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2325S325FtCctTc10641064All0.000204
ORF1ab/nsp2325S325FtCctTc193193B.1.1.70.000173
ORF1ab/nsp2325S325FtCctTc113113AY.4.20.002451
ORF1ab/nsp2325S325FtCctTc9999B.1.1.1810.45
ORF1ab/nsp2325S325FtCctTc9595AY.1030.00059
ORF1ab/nsp2325S325FtCctTc8888B.1.177.860.016144
ORF1ab/nsp2325S325FtCctTc4747B.1.617.20.000177
ORF1ab/nsp2325S325FtCctTc3939B.1.10.000707
ORF1ab/nsp2325S325FtCctTc3333B.10.000302
ORF1ab/nsp2325S325FtCctTc3131AY.40.000048
ORF1ab/nsp2325S325FtCctTc2828AY.390.000692
ORF1ab/nsp2325S325FtCctTc2222AY.440.000134
ORF1ab/nsp2325S325FtCctTc2020AY.840.008749
ORF1ab/nsp2325S325FtCctTc2020B.1.5960.001743
ORF1ab/nsp2325S325FtCctTc1717B.1.20.00015
ORF1ab/nsp2325S325FtCctTc1515AY.420.000603
ORF1ab/nsp2325S325FtCctTc1111AY.250.000066
ORF1ab/nsp2325S325FtCctTc99AY.30.00009
ORF1ab/nsp2325S325FtCctTc88AY.200.000311
ORF1ab/nsp2325S325FtCctTc88B.1.1770.000105
ORF1ab/nsp2325S325FtCctTc77AY.1190.000247
ORF1ab/nsp2325S325FtCctTc77AY.430.000031
ORF1ab/nsp2325S325FtCctTc77AY.750.000392
ORF1ab/nsp2325S325FtCctTc77B.1.1.2320.012704
ORF1ab/nsp2325S325FtCctTc66AY.1020.000159
ORF1ab/nsp2325S325FtCctTc66AY.260.00017
ORF1ab/nsp2325S325FtCctTc66AY.70.001176
ORF1ab/nsp2325S325FtCctTc66B.1.258.110.002378
ORF1ab/nsp2325S325FtCctTc55AY.450.000608
ORF1ab/nsp2325S325FtCctTc55B.1.1.5250.027322
ORF1ab/nsp2325S325FtCctTc55B.1.4290.000118
ORF1ab/nsp2325S325FtCctTc55P.10.000079
ORF1ab/nsp2325S325FtCctTc44A0.001548
ORF1ab/nsp2325S325FtCctTc44AY.1180.000251
ORF1ab/nsp2325S325FtCctTc44AY.290.000063
ORF1ab/nsp2325S325FtCctTc44B.1.4970.001259
ORF1ab/nsp2325S325FtCctTc33AY.540.000286
ORF1ab/nsp2325S325FtCctTc33AY.60.000123
ORF1ab/nsp2325S325FtCctTc33AY.9.10.000251
ORF1ab/nsp2325S325FtCctTc33AY.98.10.000145
ORF1ab/nsp2325S325FtCctTc33B.1.2430.000209
ORF1ab/nsp2325S325FtCctTc33B.1.3510.000089
ORF1ab/nsp2325S325FtCctTc33B.1.360.000438
ORF1ab/nsp2325S325FtCctTc33Q.30.000435
ORF1ab/nsp2325S325FtCctTc220.111111
ORF1ab/nsp2325S325FtCctTc22AP.10.003003
ORF1ab/nsp2325S325FtCctTc22AY.1170.000169
ORF1ab/nsp2325S325FtCctTc22AY.1200.000074
ORF1ab/nsp2325S325FtCctTc22AY.4.40.000818
ORF1ab/nsp2325S325FtCctTc22B0.000256
ORF1ab/nsp2325S325FtCctTc22B.1.1.5190.000079
ORF1ab/nsp2325S325FtCctTc22B.1.6230.001073
ORF1ab/nsp2325S325FtCctTc11AY.1070.000466
ORF1ab/nsp2325S325FtCctTc11AY.1130.000142
ORF1ab/nsp2325S325FtCctTc11AY.116.10.000311
ORF1ab/nsp2325S325FtCctTc11AY.120.10.000321
ORF1ab/nsp2325S325FtCctTc11AY.1210.000135
ORF1ab/nsp2325S325FtCctTc11AY.330.000067
ORF1ab/nsp2325S325FtCctTc11AY.39.10.00004
ORF1ab/nsp2325S325FtCctTc11AY.4.2.10.000149
ORF1ab/nsp2325S325FtCctTc11AY.460.000104
ORF1ab/nsp2325S325FtCctTc11AY.470.000031
ORF1ab/nsp2325S325FtCctTc11AY.510.000909
ORF1ab/nsp2325S325FtCctTc11AY.610.000105
ORF1ab/nsp2325S325FtCctTc11AY.690.000187
ORF1ab/nsp2325S325FtCctTc11AY.75.10.00018
ORF1ab/nsp2325S325FtCctTc11AY.90.000068
ORF1ab/nsp2325S325FtCctTc11AY.980.000079
ORF1ab/nsp2325S325FtCctTc11B.1.1.2190.005
ORF1ab/nsp2325S325FtCctTc11B.1.1.330.000421
ORF1ab/nsp2325S325FtCctTc11B.1.1.5260.003546
ORF1ab/nsp2325S325FtCctTc11B.1.1.700.000341
ORF1ab/nsp2325S325FtCctTc11B.1.177.60.000977
ORF1ab/nsp2325S325FtCctTc11B.1.2580.000067
ORF1ab/nsp2325S325FtCctTc11B.1.258.170.000104
ORF1ab/nsp2325S325FtCctTc11B.1.3110.000275
ORF1ab/nsp2325S325FtCctTc11B.1.3490.000715
ORF1ab/nsp2325S325FtCctTc11B.1.3690.000285
ORF1ab/nsp2325S325FtCctTc11B.1.438.10.000107
ORF1ab/nsp2325S325FtCctTc11B.1.466.20.000391
ORF1ab/nsp2325S325FtCctTc11B.1.5260.000024
ORF1ab/nsp2325S325FtCctTc11B.1.5410.004425
ORF1ab/nsp2325S325FtCctTc11B.1.5640.000426
ORF1ab/nsp2325S325FtCctTc11B.1.5750.000303
ORF1ab/nsp2325S325FtCctTc11B.1.575.10.002439
ORF1ab/nsp2325S325FtCctTc11C.180.002591
ORF1ab/nsp2325S325FtCctTc11C.300.001727
ORF1ab/nsp2325S325FtCctTc11C.360.000911
ORF1ab/nsp2325S325FtCctTc11C.36.3.10.002717
ORF1ab/nsp2325S325FtCctTc11D.20.000075
ORF1ab/nsp2325S325FtCctTc11P.1.140.000048
ORF1ab/nsp2325S325FtCctTc11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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