CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = S248G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2248S248GS428GnonsynAgcGgc177717740.9983121547-1549
ORF1ab/nsp2248S248GS428GnonsynAgCGgT177720.001125491547-1549
ORF1ab/nsp2248S248GS428GnonsynAgCGgA177710.0005627461547-1549

Details of the mutation S248G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2248S248GAgcGgc17741777All0.000339
ORF1ab/nsp2248S248GAgCGgT21777All0
ORF1ab/nsp2248S248GAgCGgA11777All0
ORF1ab/nsp2248S248GAgcGgc406406B.1.1.2070.479905
ORF1ab/nsp2248S248GAgcGgc251251B.1.1.70.000225
ORF1ab/nsp2248S248GAgcGgc190190B.1.20.001673
ORF1ab/nsp2248S248GAgcGgc8282AY.40.000128
ORF1ab/nsp2248S248GAgcGgc6465P.10.001008
ORF1ab/nsp2248S248GAgCGgA165P.10.000016
ORF1ab/nsp2248S248GAgcGgc6161B.10.000559
ORF1ab/nsp2248S248GAgcGgc5454AY.440.000329
ORF1ab/nsp2248S248GAgcGgc5454B.1.1820.391304
ORF1ab/nsp2248S248GAgcGgc4949AY.1030.000304
ORF1ab/nsp2248S248GAgcGgc2727AY.250.000162
ORF1ab/nsp2248S248GAgcGgc2323B.1.617.20.000087
ORF1ab/nsp2248S248GAgcGgc2121B.1.2320.011284
ORF1ab/nsp2248S248GAgcGgc2020B.1.10.000363
ORF1ab/nsp2248S248GAgcGgc1919B.1.177.160.012625
ORF1ab/nsp2248S248GAgcGgc1717B.1.1770.000224
ORF1ab/nsp2248S248GAgcGgc1616A.10.00451
ORF1ab/nsp2248S248GAgcGgc1616B.1.6330.666667
ORF1ab/nsp2248S248GAgcGgc1414AY.390.000346
ORF1ab/nsp2248S248GAgcGgc1414AY.9.20.000514
ORF1ab/nsp2248S248GAgcGgc1313B.1.2430.000905
ORF1ab/nsp2248S248GAgcGgc1212AY.130.001932
ORF1ab/nsp2248S248GAgcGgc1212AY.430.000053
ORF1ab/nsp2248S248GAgcGgc1212B.1.1.1890.018154
ORF1ab/nsp2248S248GAgcGgc1111B.1.2580.000732
ORF1ab/nsp2248S248GAgcGgc1111B.1.575.20.052885
ORF1ab/nsp2248S248GAgcGgc1010AY.200.000389
ORF1ab/nsp2248S248GAgcGgc1010AY.420.000402
ORF1ab/nsp2248S248GAgcGgc99AY.1020.000239
ORF1ab/nsp2248S248GAgcGgc99AY.290.000142
ORF1ab/nsp2248S248GAgcGgc99B.1.1.280.002801
ORF1ab/nsp2248S248GAgcGgc99B.1.6210.000797
ORF1ab/nsp2248S248GAgcGgc66AY.260.00017
ORF1ab/nsp2248S248GAgcGgc66AY.610.000629
ORF1ab/nsp2248S248GAgcGgc66AY.90.000406
ORF1ab/nsp2248S248GAgcGgc66AY.98.10.000291
ORF1ab/nsp2248S248GAgcGgc66B.1.1.3060.00263
ORF1ab/nsp2248S248GAgcGgc66B.1.5970.027778
ORF1ab/nsp2248S248GAgcGgc55AY.1200.000186
ORF1ab/nsp2248S248GAgcGgc55AY.30.00005
ORF1ab/nsp2248S248GAgcGgc55AY.450.000608
ORF1ab/nsp2248S248GAgcGgc55AY.60.000206
ORF1ab/nsp2248S248GAgcGgc55B.1.1.590.032468
ORF1ab/nsp2248S248GAgcGgc55B.1.177.810.000947
ORF1ab/nsp2248S248GAgcGgc55B.1.3510.000149
ORF1ab/nsp2248S248GAgcGgc55B.1.6280.001762
ORF1ab/nsp2248S248GAgcGgc55C.370.00058
ORF1ab/nsp2248S248GAgcGgc44AY.1190.000141
ORF1ab/nsp2248S248GAgcGgc44B0.000511
ORF1ab/nsp2248S248GAgcGgc44B.1.1.1290.036697
ORF1ab/nsp2248S248GAgcGgc44B.1.5300.028571
ORF1ab/nsp2248S248GAgcGgc33AU.30.006329
ORF1ab/nsp2248S248GAgcGgc33AY.1180.000188
ORF1ab/nsp2248S248GAgcGgc33AY.39.10.000119
ORF1ab/nsp2248S248GAgcGgc33AY.46.60.000217
ORF1ab/nsp2248S248GAgcGgc33AY.50.000062
ORF1ab/nsp2248S248GAgcGgc33AY.9.10.000251
ORF1ab/nsp2248S248GAgcGgc33B.1.1.3510.00838
ORF1ab/nsp2248S248GAgcGgc33B.1.1.380.176471
ORF1ab/nsp2248S248GAgcGgc33B.1.1.500.002037
ORF1ab/nsp2248S248GAgcGgc33B.1.1.5190.000119
ORF1ab/nsp2248S248GAgcGgc33B.1.1.630.001157
ORF1ab/nsp2248S248GAgcGgc33B.1.2210.000213
ORF1ab/nsp2248S248GAgcGgc33B.1.360.000438
ORF1ab/nsp2248S248GAgcGgc33B.1.4330.009585
ORF1ab/nsp2248S248GAgcGgc33B.1.4590.012245
ORF1ab/nsp2248S248GAgcGgc33B.1.5960.000261
ORF1ab/nsp2248S248GAgcGgc33P.1.120.001452
ORF1ab/nsp2248S248GAgcGgc33P.1.150.000697
ORF1ab/nsp2248S248GAgCGgT220.111111
ORF1ab/nsp2248S248GAgcGgc22A.2.50.000998
ORF1ab/nsp2248S248GAgcGgc22AY.1000.000092
ORF1ab/nsp2248S248GAgcGgc22AY.330.000134
ORF1ab/nsp2248S248GAgcGgc22AY.340.000194
ORF1ab/nsp2248S248GAgcGgc22AY.370.000632
ORF1ab/nsp2248S248GAgcGgc22AY.4.20.000043
ORF1ab/nsp2248S248GAgcGgc22AY.470.000062
ORF1ab/nsp2248S248GAgcGgc22AY.750.000112
ORF1ab/nsp2248S248GAgcGgc22AY.980.000158
ORF1ab/nsp2248S248GAgcGgc22AY.990.002099
ORF1ab/nsp2248S248GAgcGgc22B.1.1.2370.010811
ORF1ab/nsp2248S248GAgcGgc22B.1.1.2970.004474
ORF1ab/nsp2248S248GAgcGgc22B.1.1.3480.001592
ORF1ab/nsp2248S248GAgcGgc22B.1.1.3630.011976
ORF1ab/nsp2248S248GAgcGgc22B.1.1.3910.017094
ORF1ab/nsp2248S248GAgcGgc22B.1.1.4090.005666
ORF1ab/nsp2248S248GAgcGgc22B.1.1600.000062
ORF1ab/nsp2248S248GAgcGgc22B.1.177.580.002663
ORF1ab/nsp2248S248GAgcGgc22B.1.177.790.004684
ORF1ab/nsp2248S248GAgcGgc22B.1.36.290.001035
ORF1ab/nsp2248S248GAgcGgc22B.1.36.310.003503
ORF1ab/nsp2248S248GAgcGgc22B.1.4000.000858
ORF1ab/nsp2248S248GAgcGgc22B.1.4290.000047
ORF1ab/nsp2248S248GAgcGgc22B.1.5230.004902
ORF1ab/nsp2248S248GAgcGgc22P.1.140.000096
ORF1ab/nsp2248S248GAgcGgc11AY.1060.000335
ORF1ab/nsp2248S248GAgcGgc11AY.1130.000142
ORF1ab/nsp2248S248GAgcGgc11AY.230.00007
ORF1ab/nsp2248S248GAgcGgc11AY.360.000148
ORF1ab/nsp2248S248GAgcGgc11AY.400.000964
ORF1ab/nsp2248S248GAgcGgc11AY.460.000104
ORF1ab/nsp2248S248GAgcGgc11AY.46.20.000635
ORF1ab/nsp2248S248GAgcGgc11AY.5.20.002463
ORF1ab/nsp2248S248GAgcGgc11AY.650.000533
ORF1ab/nsp2248S248GAgcGgc11AY.770.001127
ORF1ab/nsp2248S248GAgcGgc11AY.910.00073
ORF1ab/nsp2248S248GAgcGgc11B.1.1.10.000327
ORF1ab/nsp2248S248GAgcGgc11B.1.1.1700.001247
ORF1ab/nsp2248S248GAgcGgc11B.1.1.2200.001859
ORF1ab/nsp2248S248GAgcGgc11B.1.1.2560.013699
ORF1ab/nsp2248S248GAgcGgc11B.1.1.2940.001266
ORF1ab/nsp2248S248GAgcGgc11B.1.1.330.000421
ORF1ab/nsp2248S248GAgcGgc11B.1.1.340.013158
ORF1ab/nsp2248S248GAgcGgc11B.1.1.370.000193
ORF1ab/nsp2248S248GAgcGgc11B.1.1.3720.000689
ORF1ab/nsp2248S248GAgcGgc11B.1.1.4340.000349
ORF1ab/nsp2248S248GAgcGgc11B.1.1.4480.002033
ORF1ab/nsp2248S248GAgcGgc11B.1.110.30.000718
ORF1ab/nsp2248S248GAgcGgc11B.1.1420.002899
ORF1ab/nsp2248S248GAgcGgc11B.1.177.40.000211
ORF1ab/nsp2248S248GAgcGgc11B.1.177.520.001757
ORF1ab/nsp2248S248GAgcGgc11B.1.177.730.000566
ORF1ab/nsp2248S248GAgcGgc11B.1.177.770.000726
ORF1ab/nsp2248S248GAgcGgc11B.1.177.860.000183
ORF1ab/nsp2248S248GAgcGgc11B.1.214.20.0006
ORF1ab/nsp2248S248GAgcGgc11B.1.2360.002053
ORF1ab/nsp2248S248GAgcGgc11B.1.2400.000216
ORF1ab/nsp2248S248GAgcGgc11B.1.36.170.000494
ORF1ab/nsp2248S248GAgcGgc11B.1.36.220.001208
ORF1ab/nsp2248S248GAgcGgc11B.1.3690.000285
ORF1ab/nsp2248S248GAgcGgc11B.1.4150.014286
ORF1ab/nsp2248S248GAgcGgc11B.1.4270.00005
ORF1ab/nsp2248S248GAgcGgc11B.1.5260.000024
ORF1ab/nsp2248S248GAgcGgc11B.1.5400.009709
ORF1ab/nsp2248S248GAgcGgc11B.1.617.10.000129
ORF1ab/nsp2248S248GAgcGgc11B.1.6230.000536
ORF1ab/nsp2248S248GAgcGgc11B.60.00091
ORF1ab/nsp2248S248GAgcGgc11B.610.005747
ORF1ab/nsp2248S248GAgcGgc11C.37.10.002618
ORF1ab/nsp2248S248GAgcGgc11P.1.100.000269
ORF1ab/nsp2248S248GAgcGgc11P.1.170.000162
ORF1ab/nsp2248S248GAgcGgc11P.1.20.001156
ORF1ab/nsp2248S248GAgcGgc11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.