CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = R218R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2218R218RR398RsyncgTcgC1091000.9174311457-1459
ORF1ab/nsp2218R218RR398RsyncgTcgG10960.05504591457-1459
ORF1ab/nsp2218R218RR398RsyncgTcgA10930.02752291457-1459

Details of the mutation R218R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2218R218RcgTcgC100109All0.000019
ORF1ab/nsp2218R218RcgTcgG6109All0.000001
ORF1ab/nsp2218R218RcgTcgA3109All0.000001
ORF1ab/nsp2218R218RcgTcgC1819B.1.1.70.000016
ORF1ab/nsp2218R218RcgTcgA119B.1.1.70.000001
ORF1ab/nsp2218R218RcgTcgC1617B.1.617.20.00006
ORF1ab/nsp2218R218RcgTcgG117B.1.617.20.000004
ORF1ab/nsp2218R218RcgTcgC1212B.1.10.000218
ORF1ab/nsp2218R218RcgTcgC46B.1.20.000035
ORF1ab/nsp2218R218RcgTcgG16B.1.20.000009
ORF1ab/nsp2218R218RcgTcgA16B.1.20.000009
ORF1ab/nsp2218R218RcgTcgC66B.1.6210.000531
ORF1ab/nsp2218R218RcgTcgC44AY.1200.000149
ORF1ab/nsp2218R218RcgTcgC44B.10.000037
ORF1ab/nsp2218R218RcgTcgC33AY.1030.000019
ORF1ab/nsp2218R218RcgTcgC33AY.40.000005
ORF1ab/nsp2218R218RcgTcgC220.111111
ORF1ab/nsp2218R218RcgTcgC22A0.000774
ORF1ab/nsp2218R218RcgTcgC22AY.1060.00067
ORF1ab/nsp2218R218RcgTcgC22AY.1140.000462
ORF1ab/nsp2218R218RcgTcgC22AY.30.00002
ORF1ab/nsp2218R218RcgTcgC22AY.330.000134
ORF1ab/nsp2218R218RcgTcgC22AY.550.001835
ORF1ab/nsp2218R218RcgTcgC12B.1.1770.000013
ORF1ab/nsp2218R218RcgTcgA12B.1.1770.000013
ORF1ab/nsp2218R218RcgTcgC22P.30.00319
ORF1ab/nsp2218R218RcgTcgC11AU.10.001266
ORF1ab/nsp2218R218RcgTcgC11AY.160.00038
ORF1ab/nsp2218R218RcgTcgC11AY.470.000031
ORF1ab/nsp2218R218RcgTcgC11AY.590.00053
ORF1ab/nsp2218R218RcgTcgG11AY.690.000187
ORF1ab/nsp2218R218RcgTcgC11AY.9.10.000084
ORF1ab/nsp2218R218RcgTcgC11B.1.1.700.000341
ORF1ab/nsp2218R218RcgTcgG11B.1.110.30.000718
ORF1ab/nsp2218R218RcgTcgC11B.1.1600.000031
ORF1ab/nsp2218R218RcgTcgC11B.1.2210.000071
ORF1ab/nsp2218R218RcgTcgC11B.1.2430.00007
ORF1ab/nsp2218R218RcgTcgC11B.1.360.000146
ORF1ab/nsp2218R218RcgTcgG11B.1.36.170.000494
ORF1ab/nsp2218R218RcgTcgC11B.1.3750.00082
ORF1ab/nsp2218R218RcgTcgG11B.1.3960.000706
ORF1ab/nsp2218R218RcgTcgC11B.1.4000.000429
ORF1ab/nsp2218R218RcgTcgC11P.1.10.000318

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.