CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = P624S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2624P624SP804SnonsynCctTct483748340.999382675-2677
ORF1ab/nsp2624P624SP804SnonsynCcTTcA483720.0004134792675-2677
ORF1ab/nsp2624P624SP804SnonsynCCtAGt483710.000206742675-2677

Details of the mutation P624S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2624P624SCctTct48344837All0.000925
ORF1ab/nsp2624P624SCcTTcA24837All0
ORF1ab/nsp2624P624SCCtAGt14837All0
ORF1ab/nsp2624P624SCctTct12491249AY.40.001944
ORF1ab/nsp2624P624SCctTct11251125AY.430.004984
ORF1ab/nsp2624P624SCctTct513514B.1.1.70.000459
ORF1ab/nsp2624P624SCCtAGt1514B.1.1.70.000001
ORF1ab/nsp2624P624SCctTct193193B.1.20.001699
ORF1ab/nsp2624P624SCctTct149149AY.1030.000925
ORF1ab/nsp2624P624SCctTct149149B.1.617.20.000561
ORF1ab/nsp2624P624SCctTct114114P.10.001796
ORF1ab/nsp2624P624SCctTct102102B.1.4290.0024
ORF1ab/nsp2624P624SCctTct6767AY.440.000408
ORF1ab/nsp2624P624SCctTct6262AA.51
ORF1ab/nsp2624P624SCctTct5454AY.980.004266
ORF1ab/nsp2624P624SCctTct4949B.1.1770.000645
ORF1ab/nsp2624P624SCctTct4444AY.39.10.001743
ORF1ab/nsp2624P624SCctTct4444B.1.10.000798
ORF1ab/nsp2624P624SCctTct4141B.1.4270.00207
ORF1ab/nsp2624P624SCctTct4040AY.4.10.029499
ORF1ab/nsp2624P624SCctTct3737B.1.1.5190.001469
ORF1ab/nsp2624P624SCctTct3636B.1.2430.002505
ORF1ab/nsp2624P624SCctTct3030AY.250.00018
ORF1ab/nsp2624P624SCctTct3030B.1.1.5000.6
ORF1ab/nsp2624P624SCctTct2929Q.10.003663
ORF1ab/nsp2624P624SCctTct2626P.1.140.001243
ORF1ab/nsp2624P624SCctTct2525B.10.000229
ORF1ab/nsp2624P624SCctTct2525B.1.36.170.012352
ORF1ab/nsp2624P624SCctTct2323AY.1020.00061
ORF1ab/nsp2624P624SCctTct2222AY.30.000219
ORF1ab/nsp2624P624SCctTct2222AY.750.001232
ORF1ab/nsp2624P624SCctTct2121B.1.5260.000494
ORF1ab/nsp2624P624SCctTct1919AY.900.013005
ORF1ab/nsp2624P624SCctTct1919B.1.1.2770.014416
ORF1ab/nsp2624P624SCctTct1717AY.390.00042
ORF1ab/nsp2624P624SCctTct1515B.1.36.10.017104
ORF1ab/nsp2624P624SCctTct1313AY.230.000907
ORF1ab/nsp2624P624SCctTct1212AY.1100.001352
ORF1ab/nsp2624P624SCctTct1212AY.420.000483
ORF1ab/nsp2624P624SCctTct1212B.1.160.260.029056
ORF1ab/nsp2624P624SCctTct1111AY.260.000311
ORF1ab/nsp2624P624SCctTct1111B.1.3510.000327
ORF1ab/nsp2624P624SCctTct1010AY.290.000158
ORF1ab/nsp2624P624SCctTct1010B.1.36.180.004202
ORF1ab/nsp2624P624SCctTct99AY.170.07377
ORF1ab/nsp2624P624SCctTct88B.1.1600.00025
ORF1ab/nsp2624P624SCctTct88C.370.000929
ORF1ab/nsp2624P624SCctTct77AY.1130.000997
ORF1ab/nsp2624P624SCctTct77AY.50.000145
ORF1ab/nsp2624P624SCctTct77AY.98.10.000339
ORF1ab/nsp2624P624SCctTct77B.1.1.2040.021277
ORF1ab/nsp2624P624SCctTct77B.1.2580.000466
ORF1ab/nsp2624P624SCctTct66AY.1190.000212
ORF1ab/nsp2624P624SCctTct66AY.4.50.000645
ORF1ab/nsp2624P624SCctTct66AY.460.000624
ORF1ab/nsp2624P624SCctTct66B.1.1.2430.02449
ORF1ab/nsp2624P624SCctTct66B.1.1.280.001867
ORF1ab/nsp2624P624SCctTct66B.1.360.000875
ORF1ab/nsp2624P624SCctTct66B.1.6200.005676
ORF1ab/nsp2624P624SCctTct55AY.46.60.000361
ORF1ab/nsp2624P624SCctTct55AY.470.000156
ORF1ab/nsp2624P624SCctTct55B.1.177.860.000917
ORF1ab/nsp2624P624SCctTct55B.1.6120.013263
ORF1ab/nsp2624P624SCctTct55P.40.019011
ORF1ab/nsp2624P624SCctTct44A.10.001127
ORF1ab/nsp2624P624SCctTct44AY.200.000155
ORF1ab/nsp2624P624SCctTct44AY.330.000267
ORF1ab/nsp2624P624SCctTct44AY.450.000487
ORF1ab/nsp2624P624SCctTct44AY.610.000419
ORF1ab/nsp2624P624SCctTct44B.1.2230.011111
ORF1ab/nsp2624P624SCctTct44B.1.36.80.004
ORF1ab/nsp2624P624SCctTct44B.1.5700.011765
ORF1ab/nsp2624P624SCctTct44Q.80.00066
ORF1ab/nsp2624P624SCctTct33AY.1210.000406
ORF1ab/nsp2624P624SCctTct33AY.140.000264
ORF1ab/nsp2624P624SCctTct33AY.46.20.001906
ORF1ab/nsp2624P624SCctTct33AY.640.001786
ORF1ab/nsp2624P624SCctTct33AY.7.20.001678
ORF1ab/nsp2624P624SCctTct33AY.880.002653
ORF1ab/nsp2624P624SCctTct33B.1.1.2140.000166
ORF1ab/nsp2624P624SCctTct33B.1.177.40.000633
ORF1ab/nsp2624P624SCctTct33B.1.2390.003663
ORF1ab/nsp2624P624SCctTct33B.1.5510.003871
ORF1ab/nsp2624P624SCctTct33B.1.6210.000266
ORF1ab/nsp2624P624SCctTct33C.160.003181
ORF1ab/nsp2624P624SCcTTcA220.111111
ORF1ab/nsp2624P624SCctTct22A.2.50.000998
ORF1ab/nsp2624P624SCctTct22AY.1000.000092
ORF1ab/nsp2624P624SCctTct22AY.1040.003968
ORF1ab/nsp2624P624SCctTct22AY.350.000466
ORF1ab/nsp2624P624SCctTct22AY.360.000296
ORF1ab/nsp2624P624SCctTct22AY.4.20.000043
ORF1ab/nsp2624P624SCctTct22AY.4.40.000818
ORF1ab/nsp2624P624SCctTct22AY.5.30.000675
ORF1ab/nsp2624P624SCctTct22AY.60.000082
ORF1ab/nsp2624P624SCctTct22AY.730.001331
ORF1ab/nsp2624P624SCctTct22AY.840.000875
ORF1ab/nsp2624P624SCctTct22AY.90.000135
ORF1ab/nsp2624P624SCctTct22AY.9.20.000073
ORF1ab/nsp2624P624SCctTct22AY.910.001461
ORF1ab/nsp2624P624SCctTct22B.1.1.3060.000877
ORF1ab/nsp2624P624SCctTct22B.1.1.3080.023529
ORF1ab/nsp2624P624SCctTct22B.1.1.3110.000716
ORF1ab/nsp2624P624SCctTct22B.1.1.330.000842
ORF1ab/nsp2624P624SCctTct22B.1.1.500.001358
ORF1ab/nsp2624P624SCctTct22B.1.177.350.001382
ORF1ab/nsp2624P624SCctTct22B.1.177.420.001789
ORF1ab/nsp2624P624SCctTct22B.1.177.560.001335
ORF1ab/nsp2624P624SCctTct22B.1.2210.000142
ORF1ab/nsp2624P624SCctTct22B.1.2340.000264
ORF1ab/nsp2624P624SCctTct22B.1.3560.003454
ORF1ab/nsp2624P624SCctTct22B.1.36.290.001035
ORF1ab/nsp2624P624SCctTct22B.1.466.20.000782
ORF1ab/nsp2624P624SCctTct22B.1.5300.014286
ORF1ab/nsp2624P624SCctTct22B.1.5550.044444
ORF1ab/nsp2624P624SCctTct22B.1.5820.000981
ORF1ab/nsp2624P624SCctTct22B.1.5880.00182
ORF1ab/nsp2624P624SCctTct22B.1.5950.000522
ORF1ab/nsp2624P624SCctTct22B.1.5960.000174
ORF1ab/nsp2624P624SCctTct22B.40.004415
ORF1ab/nsp2624P624SCctTct22P.20.000373
ORF1ab/nsp2624P624SCctTct11A.20.000662
ORF1ab/nsp2624P624SCctTct11A.270.001656
ORF1ab/nsp2624P624SCctTct11AE.80.000489
ORF1ab/nsp2624P624SCctTct11AM.40.003571
ORF1ab/nsp2624P624SCctTct11AU.30.00211
ORF1ab/nsp2624P624SCctTct11AY.10.000396
ORF1ab/nsp2624P624SCctTct11AY.1060.000335
ORF1ab/nsp2624P624SCctTct11AY.1080.001103
ORF1ab/nsp2624P624SCctTct11AY.1180.000063
ORF1ab/nsp2624P624SCctTct11AY.1200.000037
ORF1ab/nsp2624P624SCctTct11AY.130.000161
ORF1ab/nsp2624P624SCctTct11AY.240.000431
ORF1ab/nsp2624P624SCctTct11AY.320.000532
ORF1ab/nsp2624P624SCctTct11AY.340.000097
ORF1ab/nsp2624P624SCctTct11AY.34.10.00051
ORF1ab/nsp2624P624SCctTct11AY.39.20.001541
ORF1ab/nsp2624P624SCctTct11AY.4.2.10.000149
ORF1ab/nsp2624P624SCctTct11AY.410.000294
ORF1ab/nsp2624P624SCctTct11AY.46.50.000198
ORF1ab/nsp2624P624SCctTct11AY.5.40.000277
ORF1ab/nsp2624P624SCctTct11AY.520.000814
ORF1ab/nsp2624P624SCctTct11AY.530.000288
ORF1ab/nsp2624P624SCctTct11AY.550.000917
ORF1ab/nsp2624P624SCctTct11AY.620.000436
ORF1ab/nsp2624P624SCctTct11AY.670.000464
ORF1ab/nsp2624P624SCctTct11AY.690.000187
ORF1ab/nsp2624P624SCctTct11AY.710.000475
ORF1ab/nsp2624P624SCctTct11AY.760.004831
ORF1ab/nsp2624P624SCctTct11AY.850.000427
ORF1ab/nsp2624P624SCctTct11AY.890.004902
ORF1ab/nsp2624P624SCctTct11AY.9.10.000084
ORF1ab/nsp2624P624SCctTct11AY.950.000761
ORF1ab/nsp2624P624SCctTct11AY.960.002075
ORF1ab/nsp2624P624SCctTct11AY.99.20.000092
ORF1ab/nsp2624P624SCctTct11B.1.1.1940.00495
ORF1ab/nsp2624P624SCctTct11B.1.1.2320.001815
ORF1ab/nsp2624P624SCctTct11B.1.1.2860.002899
ORF1ab/nsp2624P624SCctTct11B.1.1.3010.001179
ORF1ab/nsp2624P624SCctTct11B.1.1.3070.002532
ORF1ab/nsp2624P624SCctTct11B.1.1.3150.008475
ORF1ab/nsp2624P624SCctTct11B.1.1.340.013158
ORF1ab/nsp2624P624SCctTct11B.1.1.3970.002252
ORF1ab/nsp2624P624SCctTct11B.1.1.4320.001266
ORF1ab/nsp2624P624SCctTct11B.1.1.5230.001563
ORF1ab/nsp2624P624SCctTct11B.1.1.630.000386
ORF1ab/nsp2624P624SCctTct11B.1.160.140.002119
ORF1ab/nsp2624P624SCctTct11B.1.177.120.000152
ORF1ab/nsp2624P624SCctTct11B.1.177.210.000076
ORF1ab/nsp2624P624SCctTct11B.1.177.230.003236
ORF1ab/nsp2624P624SCctTct11B.1.177.530.002392
ORF1ab/nsp2624P624SCctTct11B.1.177.570.000281
ORF1ab/nsp2624P624SCctTct11B.1.177.600.000218
ORF1ab/nsp2624P624SCctTct11B.1.177.80.000752
ORF1ab/nsp2624P624SCctTct11B.1.177.850.005435
ORF1ab/nsp2624P624SCctTct11B.1.2400.000216
ORF1ab/nsp2624P624SCctTct11B.1.351.30.000876
ORF1ab/nsp2624P624SCctTct11B.1.36.100.004785
ORF1ab/nsp2624P624SCctTct11B.1.36.250.002208
ORF1ab/nsp2624P624SCctTct11B.1.3900.010638
ORF1ab/nsp2624P624SCctTct11B.1.4080.00369
ORF1ab/nsp2624P624SCctTct11B.1.428.30.012821
ORF1ab/nsp2624P624SCctTct11B.1.4380.006536
ORF1ab/nsp2624P624SCctTct11B.1.4870.019608
ORF1ab/nsp2624P624SCctTct11B.1.4970.000315
ORF1ab/nsp2624P624SCctTct11B.1.4990.00105
ORF1ab/nsp2624P624SCctTct11B.1.5130.013889
ORF1ab/nsp2624P624SCctTct11B.1.5170.000427
ORF1ab/nsp2624P624SCctTct11B.1.5270.003704
ORF1ab/nsp2624P624SCctTct11B.1.5610.000397
ORF1ab/nsp2624P624SCctTct11B.1.5770.000687
ORF1ab/nsp2624P624SCctTct11B.1.596.10.009346
ORF1ab/nsp2624P624SCctTct11B.1.6100.003546
ORF1ab/nsp2624P624SCctTct11B.1.617.10.000129
ORF1ab/nsp2624P624SCctTct11B.1.6230.000536
ORF1ab/nsp2624P624SCctTct11B.1.6280.000352
ORF1ab/nsp2624P624SCctTct11C.10.002392
ORF1ab/nsp2624P624SCctTct11D.20.000075
ORF1ab/nsp2624P624SCctTct11P.1.120.000484
ORF1ab/nsp2624P624SCctTct11P.1.150.000232
ORF1ab/nsp2624P624SCctTct11P.1.60.001946
ORF1ab/nsp2624P624SCctTct11P.1.80.004785
ORF1ab/nsp2624P624SCctTct11Q.40.000455
ORF1ab/nsp2624P624SCctTct11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.