CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = P624P

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2624P624PP804PsynccTccC3913780.9667522675-2677
ORF1ab/nsp2624P624PP804PsynccTccG39170.01790282675-2677
ORF1ab/nsp2624P624PP804PsynccTccA39160.01534532675-2677

Details of the mutation P624P within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2624P624PccTccC378391All0.000072
ORF1ab/nsp2624P624PccTccG7391All0.000001
ORF1ab/nsp2624P624PccTccA6391All0.000001
ORF1ab/nsp2624P624PccTccC329329B.10.003013
ORF1ab/nsp2624P624PccTccC1011B.1.1.70.000009
ORF1ab/nsp2624P624PccTccG111B.1.1.70.000001
ORF1ab/nsp2624P624PccTccC88B.1.3360.019512
ORF1ab/nsp2624P624PccTccC44AY.440.000024
ORF1ab/nsp2624P624PccTccC23AY.40.000003
ORF1ab/nsp2624P624PccTccG13AY.40.000002
ORF1ab/nsp2624P624PccTccG22AY.290.000032
ORF1ab/nsp2624P624PccTccC22B.1.1430.042553
ORF1ab/nsp2624P624PccTccC22B.1.20.000018
ORF1ab/nsp2624P624PccTccC22B.1.351.20.000605
ORF1ab/nsp2624P624PccTccC22B.1.3880.181818
ORF1ab/nsp2624P624PccTccC22B.1.617.20.000008
ORF1ab/nsp2624P624PccTccA22B.1.6370.000146
ORF1ab/nsp2624P624PccTccA22D.20.00015
ORF1ab/nsp2624P624PccTccC11AY.1110.000183
ORF1ab/nsp2624P624PccTccG11AY.1200.000037
ORF1ab/nsp2624P624PccTccC11AY.200.000039
ORF1ab/nsp2624P624PccTccC11AY.250.000006
ORF1ab/nsp2624P624PccTccC11AY.260.000028
ORF1ab/nsp2624P624PccTccC11AY.390.000025
ORF1ab/nsp2624P624PccTccC11AY.470.000031
ORF1ab/nsp2624P624PccTccC11AY.50.000021
ORF1ab/nsp2624P624PccTccC11AY.920.000287
ORF1ab/nsp2624P624PccTccC11B0.000128
ORF1ab/nsp2624P624PccTccG11B.1.1.250.000569
ORF1ab/nsp2624P624PccTccA11B.1.1.3060.000438
ORF1ab/nsp2624P624PccTccG11B.1.177.530.002392
ORF1ab/nsp2624P624PccTccC11B.1.3490.000715
ORF1ab/nsp2624P624PccTccC11B.1.36.360.000602
ORF1ab/nsp2624P624PccTccC11B.1.4170.028571
ORF1ab/nsp2624P624PccTccC11B.1.4330.003195
ORF1ab/nsp2624P624PccTccC11B.1.4700.001404
ORF1ab/nsp2624P624PccTccC11B.60.00091
ORF1ab/nsp2624P624PccTccA11C.360.000911

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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