CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = P597P

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2597P597PP777PsynccAccG503543690.8677262594-2596
ORF1ab/nsp2597P597PP777PsynccAccC50356330.125722594-2596
ORF1ab/nsp2597P597PP777PsynccAccT5035330.006554122594-2596

Details of the mutation P597P within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2597P597PccAccG43695035All0.000836
ORF1ab/nsp2597P597PccAccC6335035All0.000121
ORF1ab/nsp2597P597PccAccT335035All0.000006
ORF1ab/nsp2597P597PccAccG38743874P.1.150.900093
ORF1ab/nsp2597P597PccAccC610644B.1.1.70.000546
ORF1ab/nsp2597P597PccAccT22644B.1.1.70.00002
ORF1ab/nsp2597P597PccAccG12644B.1.1.70.000011
ORF1ab/nsp2597P597PccAccG7071P.10.001103
ORF1ab/nsp2597P597PccAccC171P.10.000016
ORF1ab/nsp2597P597PccAccG4851AY.430.000213
ORF1ab/nsp2597P597PccAccC251AY.430.000009
ORF1ab/nsp2597P597PccAccT151AY.430.000004
ORF1ab/nsp2597P597PccAccG4851B.1.617.20.000181
ORF1ab/nsp2597P597PccAccT351B.1.617.20.000011
ORF1ab/nsp2597P597PccAccG4646AY.60.001892
ORF1ab/nsp2597P597PccAccG3940AY.330.002604
ORF1ab/nsp2597P597PccAccT140AY.330.000067
ORF1ab/nsp2597P597PccAccG2527AY.1030.000155
ORF1ab/nsp2597P597PccAccC227AY.1030.000012
ORF1ab/nsp2597P597PccAccG1925AY.440.000116
ORF1ab/nsp2597P597PccAccC425AY.440.000024
ORF1ab/nsp2597P597PccAccT225AY.440.000012
ORF1ab/nsp2597P597PccAccG1819B.10.000165
ORF1ab/nsp2597P597PccAccC119B.10.000009
ORF1ab/nsp2597P597PccAccG1717C.370.001973
ORF1ab/nsp2597P597PccAccG1212AY.250.000072
ORF1ab/nsp2597P597PccAccG711AY.40.000011
ORF1ab/nsp2597P597PccAccC411AY.40.000006
ORF1ab/nsp2597P597PccAccG1011B.1.10.000181
ORF1ab/nsp2597P597PccAccC111B.1.10.000018
ORF1ab/nsp2597P597PccAccG99AE.30.290323
ORF1ab/nsp2597P597PccAccG99AY.1020.000239
ORF1ab/nsp2597P597PccAccG77AY.1000.000322
ORF1ab/nsp2597P597PccAccG46AY.390.000099
ORF1ab/nsp2597P597PccAccC26AY.390.000049
ORF1ab/nsp2597P597PccAccG55AY.1190.000177
ORF1ab/nsp2597P597PccAccC45AY.260.000113
ORF1ab/nsp2597P597PccAccG15AY.260.000028
ORF1ab/nsp2597P597PccAccG55AY.9.20.000184
ORF1ab/nsp2597P597PccAccG55AY.98.10.000242
ORF1ab/nsp2597P597PccAccG55B.1.1770.000066
ORF1ab/nsp2597P597PccAccG55P.1.160.001871
ORF1ab/nsp2597P597PccAccG44B.1.1.4340.001394
ORF1ab/nsp2597P597PccAccG44B.1.2410.003247
ORF1ab/nsp2597P597PccAccG33AY.540.000286
ORF1ab/nsp2597P597PccAccG33B.1.1.4480.006098
ORF1ab/nsp2597P597PccAccG33B.1.1.5190.000119
ORF1ab/nsp2597P597PccAccG33B.1.20.000026
ORF1ab/nsp2597P597PccAccG33B.1.2430.000209
ORF1ab/nsp2597P597PccAccG33B.1.2580.0002
ORF1ab/nsp2597P597PccAccC23B.1.3510.000059
ORF1ab/nsp2597P597PccAccG13B.1.3510.00003
ORF1ab/nsp2597P597PccAccG12AY.1200.000037
ORF1ab/nsp2597P597PccAccT12AY.1200.000037
ORF1ab/nsp2597P597PccAccG22AY.200.000078
ORF1ab/nsp2597P597PccAccG22AY.30.00002
ORF1ab/nsp2597P597PccAccG22AY.4.50.000215
ORF1ab/nsp2597P597PccAccG22AY.620.000871
ORF1ab/nsp2597P597PccAccG22AY.99.20.000184
ORF1ab/nsp2597P597PccAccG22B.1.36.70.008
ORF1ab/nsp2597P597PccAccG22C.350.001548
ORF1ab/nsp2597P597PccAccG11AD.20.000219
ORF1ab/nsp2597P597PccAccG11AY.1050.000643
ORF1ab/nsp2597P597PccAccG11AY.1160.000287
ORF1ab/nsp2597P597PccAccG11AY.140.000088
ORF1ab/nsp2597P597PccAccG11AY.290.000016
ORF1ab/nsp2597P597PccAccG11AY.3.10.000085
ORF1ab/nsp2597P597PccAccG11AY.39.10.00004
ORF1ab/nsp2597P597PccAccG11AY.4.20.000022
ORF1ab/nsp2597P597PccAccG11AY.4.2.10.000149
ORF1ab/nsp2597P597PccAccG11AY.420.00004
ORF1ab/nsp2597P597PccAccG11AY.450.000122
ORF1ab/nsp2597P597PccAccG11AY.470.000031
ORF1ab/nsp2597P597PccAccG11AY.550.000917
ORF1ab/nsp2597P597PccAccG11AY.750.000056
ORF1ab/nsp2597P597PccAccG11B.1.1.10.000327
ORF1ab/nsp2597P597PccAccT11B.1.1.100.001115
ORF1ab/nsp2597P597PccAccG11B.1.1.3060.000438
ORF1ab/nsp2597P597PccAccG11B.1.1.3980.003226
ORF1ab/nsp2597P597PccAccG11B.1.177.810.000189
ORF1ab/nsp2597P597PccAccG11B.1.2210.000071
ORF1ab/nsp2597P597PccAccT11B.1.3490.000715
ORF1ab/nsp2597P597PccAccG11B.1.3890.001002
ORF1ab/nsp2597P597PccAccG11B.1.3980.002976
ORF1ab/nsp2597P597PccAccT11B.1.4970.000315
ORF1ab/nsp2597P597PccAccG11B.1.5260.000024
ORF1ab/nsp2597P597PccAccG11C.37.10.002618
ORF1ab/nsp2597P597PccAccG11D.20.000075
ORF1ab/nsp2597P597PccAccG11N.50.001767
ORF1ab/nsp2597P597PccAccG11P.1.130.000898
ORF1ab/nsp2597P597PccAccG11Q.70.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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