CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = N435K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2435N435KN615KnonsynaaCaaA74650.8783782108-2110
ORF1ab/nsp2435N435KN615KnonsynaaCaaG7490.1216222108-2110

Details of the mutation N435K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2435N435KaaCaaA6574All0.000012
ORF1ab/nsp2435N435KaaCaaG974All0.000002
ORF1ab/nsp2435N435KaaCaaA1010B.10.000092
ORF1ab/nsp2435N435KaaCaaA910B.1.1.70.000008
ORF1ab/nsp2435N435KaaCaaG110B.1.1.70.000001
ORF1ab/nsp2435N435KaaCaaA1010B.1.6370.000731
ORF1ab/nsp2435N435KaaCaaA99B.1.1.5190.000357
ORF1ab/nsp2435N435KaaCaaA55P.10.000079
ORF1ab/nsp2435N435KaaCaaA44AY.40.000006
ORF1ab/nsp2435N435KaaCaaA44B.1.5750.001214
ORF1ab/nsp2435N435KaaCaaA120.055556
ORF1ab/nsp2435N435KaaCaaG120.055556
ORF1ab/nsp2435N435KaaCaaG22AY.1020.000053
ORF1ab/nsp2435N435KaaCaaG22AY.1180.000125
ORF1ab/nsp2435N435KaaCaaA22AY.250.000012
ORF1ab/nsp2435N435KaaCaaA22AY.440.000012
ORF1ab/nsp2435N435KaaCaaA22B.1.10.000036
ORF1ab/nsp2435N435KaaCaaG12B.1.617.20.000004
ORF1ab/nsp2435N435KaaCaaA12B.1.617.20.000004
ORF1ab/nsp2435N435KaaCaaA11AY.1100.000113
ORF1ab/nsp2435N435KaaCaaA11AY.390.000025
ORF1ab/nsp2435N435KaaCaaG11AY.460.000104
ORF1ab/nsp2435N435KaaCaaG11AY.5.40.000277
ORF1ab/nsp2435N435KaaCaaA11AY.99.20.000092
ORF1ab/nsp2435N435KaaCaaA11B.1.1.2280.003049
ORF1ab/nsp2435N435KaaCaaA11B.1.1.520.012195
ORF1ab/nsp2435N435KaaCaaA11B.1.5820.000491

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.