CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = N254N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2254N254NN434NsynaaCaaT4282428211565-1567

Details of the mutation N254N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2254N254NaaCaaT42824282All0.000819
ORF1ab/nsp2254N254NaaCaaT19431943A.2.50.969561
ORF1ab/nsp2254N254NaaCaaT622622A.2.5.20.977987
ORF1ab/nsp2254N254NaaCaaT275275B.1.1.70.000246
ORF1ab/nsp2254N254NaaCaaT208208A.2.5.11
ORF1ab/nsp2254N254NaaCaaT198198B.1.617.20.000746
ORF1ab/nsp2254N254NaaCaaT113113B.1.1600.003524
ORF1ab/nsp2254N254NaaCaaT9696A.2.5.30.989691
ORF1ab/nsp2254N254NaaCaaT5959AY.40.000092
ORF1ab/nsp2254N254NaaCaaT4747AY.200.001827
ORF1ab/nsp2254N254NaaCaaT4747B.1.20.000414
ORF1ab/nsp2254N254NaaCaaT4242AY.980.003318
ORF1ab/nsp2254N254NaaCaaT4141B.10.000376
ORF1ab/nsp2254N254NaaCaaT4040AY.250.000241
ORF1ab/nsp2254N254NaaCaaT3333AY.1020.000875
ORF1ab/nsp2254N254NaaCaaT2727AC.11
ORF1ab/nsp2254N254NaaCaaT2626AY.430.000115
ORF1ab/nsp2254N254NaaCaaT2222B.1.1.5190.000874
ORF1ab/nsp2254N254NaaCaaT1818AY.50.000372
ORF1ab/nsp2254N254NaaCaaT1515AY.1030.000093
ORF1ab/nsp2254N254NaaCaaT1515B.1.5170.006405
ORF1ab/nsp2254N254NaaCaaT1414P.1.140.000669
ORF1ab/nsp2254N254NaaCaaT1313B.1.5260.000306
ORF1ab/nsp2254N254NaaCaaT1111AY.440.000067
ORF1ab/nsp2254N254NaaCaaT1111AY.990.011542
ORF1ab/nsp2254N254NaaCaaT1111B.1.10.0002
ORF1ab/nsp2254N254NaaCaaT1010AY.30.000099
ORF1ab/nsp2254N254NaaCaaT1010AY.390.000247
ORF1ab/nsp2254N254NaaCaaT1010AY.98.10.000484
ORF1ab/nsp2254N254NaaCaaT1010B.1.1770.000132
ORF1ab/nsp2254N254NaaCaaT1010B.1.5990.036496
ORF1ab/nsp2254N254NaaCaaT1010B.1.6210.000885
ORF1ab/nsp2254N254NaaCaaT99B.1.1.4050.75
ORF1ab/nsp2254N254NaaCaaT99B.1.4290.000212
ORF1ab/nsp2254N254NaaCaaT99P.10.000142
ORF1ab/nsp2254N254NaaCaaT88B.1.1.3660.126984
ORF1ab/nsp2254N254NaaCaaT88B.1.214.30.057143
ORF1ab/nsp2254N254NaaCaaT77AY.450.000852
ORF1ab/nsp2254N254NaaCaaT66AY.1070.002796
ORF1ab/nsp2254N254NaaCaaT66AY.290.000095
ORF1ab/nsp2254N254NaaCaaT66AY.4.20.00013
ORF1ab/nsp2254N254NaaCaaT66AY.470.000187
ORF1ab/nsp2254N254NaaCaaT66B.1.4090.004687
ORF1ab/nsp2254N254NaaCaaT66B.1.5820.002944
ORF1ab/nsp2254N254NaaCaaT55AY.1210.000677
ORF1ab/nsp2254N254NaaCaaT55AY.920.001436
ORF1ab/nsp2254N254NaaCaaT55AZ.20.004105
ORF1ab/nsp2254N254NaaCaaT55B.1.3510.000149
ORF1ab/nsp2254N254NaaCaaT55B.1.36.290.002587
ORF1ab/nsp2254N254NaaCaaT55B.1.5950.001305
ORF1ab/nsp2254N254NaaCaaT44AY.39.10.000158
ORF1ab/nsp2254N254NaaCaaT44AY.9.10.000335
ORF1ab/nsp2254N254NaaCaaT44B.1.2430.000278
ORF1ab/nsp2254N254NaaCaaT44C.370.000464
ORF1ab/nsp2254N254NaaCaaT44D.20.0003
ORF1ab/nsp2254N254NaaCaaT44Z.10.011561
ORF1ab/nsp2254N254NaaCaaT33A.60.015385
ORF1ab/nsp2254N254NaaCaaT33AY.190.003421
ORF1ab/nsp2254N254NaaCaaT33AY.230.000209
ORF1ab/nsp2254N254NaaCaaT33AY.23.10.001252
ORF1ab/nsp2254N254NaaCaaT33AY.60.000123
ORF1ab/nsp2254N254NaaCaaT33B0.000383
ORF1ab/nsp2254N254NaaCaaT33B.1.1.3220.026316
ORF1ab/nsp2254N254NaaCaaT33B.1.4700.004213
ORF1ab/nsp2254N254NaaCaaT33B.1.5750.00091
ORF1ab/nsp2254N254NaaCaaT33B.1.596.10.028037
ORF1ab/nsp2254N254NaaCaaT22AY.1170.000169
ORF1ab/nsp2254N254NaaCaaT22AY.1180.000125
ORF1ab/nsp2254N254NaaCaaT22AY.160.000759
ORF1ab/nsp2254N254NaaCaaT22AY.260.000057
ORF1ab/nsp2254N254NaaCaaT22AY.4.50.000215
ORF1ab/nsp2254N254NaaCaaT22AY.420.00008
ORF1ab/nsp2254N254NaaCaaT22AY.46.40.000329
ORF1ab/nsp2254N254NaaCaaT22AY.650.001066
ORF1ab/nsp2254N254NaaCaaT22AY.750.000112
ORF1ab/nsp2254N254NaaCaaT22AY.90.000135
ORF1ab/nsp2254N254NaaCaaT22AY.950.001522
ORF1ab/nsp2254N254NaaCaaT22AY.99.20.000184
ORF1ab/nsp2254N254NaaCaaT22B.1.1.2840.000215
ORF1ab/nsp2254N254NaaCaaT22B.1.1.370.000386
ORF1ab/nsp2254N254NaaCaaT22B.1.1570.00597
ORF1ab/nsp2254N254NaaCaaT22B.1.177.320.002699
ORF1ab/nsp2254N254NaaCaaT22B.1.2390.002442
ORF1ab/nsp2254N254NaaCaaT22B.1.2580.000133
ORF1ab/nsp2254N254NaaCaaT22B.1.351.20.000605
ORF1ab/nsp2254N254NaaCaaT22B.1.3960.001411
ORF1ab/nsp2254N254NaaCaaT22B.1.4730.038462
ORF1ab/nsp2254N254NaaCaaT22B.1.5600.009259
ORF1ab/nsp2254N254NaaCaaT22Q.80.00033
ORF1ab/nsp2254N254NaaCaaT11A0.000387
ORF1ab/nsp2254N254NaaCaaT11A.10.000282
ORF1ab/nsp2254N254NaaCaaT11A.20.000662
ORF1ab/nsp2254N254NaaCaaT11A.2.40.003367
ORF1ab/nsp2254N254NaaCaaT11AE.80.000489
ORF1ab/nsp2254N254NaaCaaT11AY.1000.000046
ORF1ab/nsp2254N254NaaCaaT11AY.1110.000183
ORF1ab/nsp2254N254NaaCaaT11AY.1130.000142
ORF1ab/nsp2254N254NaaCaaT11AY.120.000316
ORF1ab/nsp2254N254NaaCaaT11AY.120.2.10.000498
ORF1ab/nsp2254N254NaaCaaT11AY.140.000088
ORF1ab/nsp2254N254NaaCaaT11AY.16.10.00047
ORF1ab/nsp2254N254NaaCaaT11AY.330.000067
ORF1ab/nsp2254N254NaaCaaT11AY.340.000097
ORF1ab/nsp2254N254NaaCaaT11AY.34.10.00051
ORF1ab/nsp2254N254NaaCaaT11AY.4.40.000409
ORF1ab/nsp2254N254NaaCaaT11AY.46.20.000635
ORF1ab/nsp2254N254NaaCaaT11AY.46.60.000072
ORF1ab/nsp2254N254NaaCaaT11AY.5.40.000277
ORF1ab/nsp2254N254NaaCaaT11AY.70.000196
ORF1ab/nsp2254N254NaaCaaT11AY.7.10.000113
ORF1ab/nsp2254N254NaaCaaT11AY.710.000475
ORF1ab/nsp2254N254NaaCaaT11AY.740.000116
ORF1ab/nsp2254N254NaaCaaT11AY.9.20.000037
ORF1ab/nsp2254N254NaaCaaT11AY.910.00073
ORF1ab/nsp2254N254NaaCaaT11AY.970.001701
ORF1ab/nsp2254N254NaaCaaT11B.1.1.1530.001095
ORF1ab/nsp2254N254NaaCaaT11B.1.1.1770.019231
ORF1ab/nsp2254N254NaaCaaT11B.1.1.2200.001859
ORF1ab/nsp2254N254NaaCaaT11B.1.1.2300.009174
ORF1ab/nsp2254N254NaaCaaT11B.1.1.250.000569
ORF1ab/nsp2254N254NaaCaaT11B.1.1.280.000311
ORF1ab/nsp2254N254NaaCaaT11B.1.1.3290.003846
ORF1ab/nsp2254N254NaaCaaT11B.1.1.330.000421
ORF1ab/nsp2254N254NaaCaaT11B.1.1.3630.005988
ORF1ab/nsp2254N254NaaCaaT11B.1.1100.004525
ORF1ab/nsp2254N254NaaCaaT11B.1.160.160.000929
ORF1ab/nsp2254N254NaaCaaT11B.1.160.330.004425
ORF1ab/nsp2254N254NaaCaaT11B.1.177.810.000189
ORF1ab/nsp2254N254NaaCaaT11B.1.177.830.001481
ORF1ab/nsp2254N254NaaCaaT11B.1.177.870.000728
ORF1ab/nsp2254N254NaaCaaT11B.1.177.90.001332
ORF1ab/nsp2254N254NaaCaaT11B.1.214.20.0006
ORF1ab/nsp2254N254NaaCaaT11B.1.2340.000132
ORF1ab/nsp2254N254NaaCaaT11B.1.2400.000216
ORF1ab/nsp2254N254NaaCaaT11B.1.360.000146
ORF1ab/nsp2254N254NaaCaaT11B.1.3670.000792
ORF1ab/nsp2254N254NaaCaaT11B.1.4270.00005
ORF1ab/nsp2254N254NaaCaaT11B.1.5250.000113
ORF1ab/nsp2254N254NaaCaaT11B.1.5610.000397
ORF1ab/nsp2254N254NaaCaaT11B.1.5700.002941
ORF1ab/nsp2254N254NaaCaaT11B.1.617.10.000129
ORF1ab/nsp2254N254NaaCaaT11B.1.621.10.000506
ORF1ab/nsp2254N254NaaCaaT11B.1.6320.006711
ORF1ab/nsp2254N254NaaCaaT11B.1.6370.000073
ORF1ab/nsp2254N254NaaCaaT11B.1.930.000934
ORF1ab/nsp2254N254NaaCaaT11B.300.014706
ORF1ab/nsp2254N254NaaCaaT11P.1.170.000162
ORF1ab/nsp2254N254NaaCaaT11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.