CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = M418T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2418M418TM598TnonsynaTgaCg117311720.9991472057-2059
ORF1ab/nsp2418M418TM598TnonsynaTGaCA117310.0008525152057-2059

Details of the mutation M418T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2418M418TaTgaCg11721173All0.000224
ORF1ab/nsp2418M418TaTGaCA11173All0
ORF1ab/nsp2418M418TaTgaCg898898AY.40.001398
ORF1ab/nsp2418M418TaTgaCg9090AY.440.000548
ORF1ab/nsp2418M418TaTgaCg7777B.1.617.20.00029
ORF1ab/nsp2418M418TaTgaCg1111AY.250.000066
ORF1ab/nsp2418M418TaTgaCg1010AY.1030.000062
ORF1ab/nsp2418M418TaTgaCg1010B.1.1.70.000009
ORF1ab/nsp2418M418TaTgaCg1010B.1.258.170.00104
ORF1ab/nsp2418M418TaTgaCg88AY.260.000226
ORF1ab/nsp2418M418TaTgaCg77B.1.20.000062
ORF1ab/nsp2418M418TaTgaCg33B.1.10.000054
ORF1ab/nsp2418M418TaTgaCg33B.1.4270.000151
ORF1ab/nsp2418M418TaTgaCg33P.1.140.000143
ORF1ab/nsp2418M418TaTgaCg22AY.1200.000074
ORF1ab/nsp2418M418TaTgaCg22AY.290.000032
ORF1ab/nsp2418M418TaTgaCg22AY.330.000134
ORF1ab/nsp2418M418TaTgaCg22AY.390.000049
ORF1ab/nsp2418M418TaTgaCg22AY.39.10.000079
ORF1ab/nsp2418M418TaTgaCg22AY.430.000009
ORF1ab/nsp2418M418TaTgaCg22AY.60.000082
ORF1ab/nsp2418M418TaTgaCg22B.1.1600.000062
ORF1ab/nsp2418M418TaTgaCg22B.1.177.40.000422
ORF1ab/nsp2418M418TaTgaCg22B.1.4290.000047
ORF1ab/nsp2418M418TaTgaCg11AY.1090.00074
ORF1ab/nsp2418M418TaTgaCg11AY.1170.000085
ORF1ab/nsp2418M418TaTgaCg11AY.120.2.10.000498
ORF1ab/nsp2418M418TaTgaCg11AY.1210.000135
ORF1ab/nsp2418M418TaTgaCg11AY.230.00007
ORF1ab/nsp2418M418TaTgaCg11AY.4.20.000022
ORF1ab/nsp2418M418TaTgaCg11AY.420.00004
ORF1ab/nsp2418M418TaTGaCA11AY.790.001211
ORF1ab/nsp2418M418TaTgaCg11AY.9.20.000037
ORF1ab/nsp2418M418TaTgaCg11B.1.1.4110.014706
ORF1ab/nsp2418M418TaTgaCg11B.1.1770.000013
ORF1ab/nsp2418M418TaTgaCg11B.1.177.560.000668
ORF1ab/nsp2418M418TaTgaCg11B.1.2340.000132
ORF1ab/nsp2418M418TaTgaCg11B.1.3200.001245
ORF1ab/nsp2418M418TaTgaCg11B.1.36.380.001642
ORF1ab/nsp2418M418TaTgaCg11B.1.5260.000024
ORF1ab/nsp2418M418TaTgaCg11B.1.5960.000087
ORF1ab/nsp2418M418TaTgaCg11B.1.5970.00463
ORF1ab/nsp2418M418TaTgaCg11B.1.6050.005952
ORF1ab/nsp2418M418TaTgaCg11B.1.6370.000073
ORF1ab/nsp2418M418TaTgaCg11D.20.000075
ORF1ab/nsp2418M418TaTgaCg11P.10.000016
ORF1ab/nsp2418M418TaTgaCg11P.1.100.000269

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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