CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = M418I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2418M418IM598InonsynatGatA5735120.8935432057-2059
ORF1ab/nsp2418M418IM598InonsynatGatT573590.1029672057-2059
ORF1ab/nsp2418M418IM598InonsynatGatC57320.00349042057-2059

Details of the mutation M418I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2418M418IatGatA512573All0.000098
ORF1ab/nsp2418M418IatGatT59573All0.000011
ORF1ab/nsp2418M418IatGatC2573All0
ORF1ab/nsp2418M418IatGatA95105B.1.1.70.000085
ORF1ab/nsp2418M418IatGatT10105B.1.1.70.000009
ORF1ab/nsp2418M418IatGatA100100B.1.5960.008714
ORF1ab/nsp2418M418IatGatA4343P.10.000677
ORF1ab/nsp2418M418IatGatA3737B.1.1.370.007136
ORF1ab/nsp2418M418IatGatA2033AY.40.000031
ORF1ab/nsp2418M418IatGatT1333AY.40.00002
ORF1ab/nsp2418M418IatGatA2324B.1.617.20.000087
ORF1ab/nsp2418M418IatGatC124B.1.617.20.000004
ORF1ab/nsp2418M418IatGatA1222B.10.00011
ORF1ab/nsp2418M418IatGatT922B.10.000082
ORF1ab/nsp2418M418IatGatC122B.10.000009
ORF1ab/nsp2418M418IatGatA1820AY.250.000108
ORF1ab/nsp2418M418IatGatT220AY.250.000012
ORF1ab/nsp2418M418IatGatA1919AY.430.000084
ORF1ab/nsp2418M418IatGatA1515AY.1020.000398
ORF1ab/nsp2418M418IatGatA1212AY.1030.000075
ORF1ab/nsp2418M418IatGatA1112B.1.20.000097
ORF1ab/nsp2418M418IatGatT112B.1.20.000009
ORF1ab/nsp2418M418IatGatA1111B.1.1.5190.000437
ORF1ab/nsp2418M418IatGatA910B.1.10.000163
ORF1ab/nsp2418M418IatGatT110B.1.10.000018
ORF1ab/nsp2418M418IatGatA88B.1.6270.016162
ORF1ab/nsp2418M418IatGatA77B.1.3240.011236
ORF1ab/nsp2418M418IatGatA56AY.440.00003
ORF1ab/nsp2418M418IatGatT16AY.440.000006
ORF1ab/nsp2418M418IatGatT55A.20.003309
ORF1ab/nsp2418M418IatGatA55B.1.3990.009671
ORF1ab/nsp2418M418IatGatA55P.1.70.001596
ORF1ab/nsp2418M418IatGatA44AY.1060.00134
ORF1ab/nsp2418M418IatGatA34AY.30.00003
ORF1ab/nsp2418M418IatGatT14AY.30.00001
ORF1ab/nsp2418M418IatGatT33AY.290.000047
ORF1ab/nsp2418M418IatGatA33AY.740.000347
ORF1ab/nsp2418M418IatGatA23B.1.617.10.000258
ORF1ab/nsp2418M418IatGatT13B.1.617.10.000129
ORF1ab/nsp2418M418IatGatA33B.270.046154
ORF1ab/nsp2418M418IatGatA22AY.310.037037
ORF1ab/nsp2418M418IatGatT12AY.4.20.000022
ORF1ab/nsp2418M418IatGatA12AY.4.20.000022
ORF1ab/nsp2418M418IatGatA22AY.50.000041
ORF1ab/nsp2418M418IatGatA22AY.610.00021
ORF1ab/nsp2418M418IatGatT22B.1.1770.000026
ORF1ab/nsp2418M418IatGatA22B.1.2580.000133
ORF1ab/nsp2418M418IatGatT12B.1.3510.00003
ORF1ab/nsp2418M418IatGatA12B.1.3510.00003
ORF1ab/nsp2418M418IatGatA12B.1.360.000146
ORF1ab/nsp2418M418IatGatT12B.1.360.000146
ORF1ab/nsp2418M418IatGatA22B.1.4130.008511
ORF1ab/nsp2418M418IatGatT12B.1.4270.00005
ORF1ab/nsp2418M418IatGatA12B.1.4270.00005
ORF1ab/nsp2418M418IatGatA22B.1.4290.000047
ORF1ab/nsp2418M418IatGatA22P.1.10.000635
ORF1ab/nsp2418M418IatGatA11AY.1000.000046
ORF1ab/nsp2418M418IatGatA11AY.1130.000142
ORF1ab/nsp2418M418IatGatA11AY.1160.000287
ORF1ab/nsp2418M418IatGatA11AY.230.00007
ORF1ab/nsp2418M418IatGatA11AY.330.000067
ORF1ab/nsp2418M418IatGatA11AY.350.000233
ORF1ab/nsp2418M418IatGatA11AY.390.000025
ORF1ab/nsp2418M418IatGatA11AY.46.30.000934
ORF1ab/nsp2418M418IatGatA11AY.46.40.000165
ORF1ab/nsp2418M418IatGatA11AY.530.000288
ORF1ab/nsp2418M418IatGatA11AY.550.000917
ORF1ab/nsp2418M418IatGatT11AY.710.000475
ORF1ab/nsp2418M418IatGatT11AY.80.000606
ORF1ab/nsp2418M418IatGatA11AY.980.000079
ORF1ab/nsp2418M418IatGatA11AY.99.20.000092
ORF1ab/nsp2418M418IatGatT11B.1.1.3050.003861
ORF1ab/nsp2418M418IatGatA11B.1.1280.000635
ORF1ab/nsp2418M418IatGatA11B.1.177.60.000977
ORF1ab/nsp2418M418IatGatT11B.1.177.730.000566
ORF1ab/nsp2418M418IatGatA11B.1.177.860.000183
ORF1ab/nsp2418M418IatGatA11B.1.36.180.00042
ORF1ab/nsp2418M418IatGatA11B.1.36.290.000517
ORF1ab/nsp2418M418IatGatT11B.1.3960.000706
ORF1ab/nsp2418M418IatGatA11B.1.5260.000024
ORF1ab/nsp2418M418IatGatA11B.1.6200.000946
ORF1ab/nsp2418M418IatGatA11B.1.6210.000089
ORF1ab/nsp2418M418IatGatT11B.1.6230.000536
ORF1ab/nsp2418M418IatGatA11P.1.120.000484
ORF1ab/nsp2418M418IatGatA11P.1.60.001946
ORF1ab/nsp2418M418IatGatA11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.