CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = M117V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2117M117VM297VnonsynAtgGtg10097100950.9998021154-1156
ORF1ab/nsp2117M117VM297VnonsynAtGGtT1009710.00009903931154-1156
ORF1ab/nsp2117M117VM297VnonsynAtGGtC1009710.00009903931154-1156

Details of the mutation M117V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2117M117VAtgGtg1009510097All0.001931
ORF1ab/nsp2117M117VAtGGtC110097All0
ORF1ab/nsp2117M117VAtGGtT110097All0
ORF1ab/nsp2117M117VAtgGtg93099309B.1.438.10.998498
ORF1ab/nsp2117M117VAtgGtg150150B.1.4380.980392
ORF1ab/nsp2117M117VAtgGtg9494AY.40.000146
ORF1ab/nsp2117M117VAtgGtg6666AY.160.025057
ORF1ab/nsp2117M117VAtgGtg6464B.10.000586
ORF1ab/nsp2117M117VAtgGtg5252B.1.438.21
ORF1ab/nsp2117M117VAtgGtg4747B.1.438.41
ORF1ab/nsp2117M117VAtgGtg3030B.1.1770.000395
ORF1ab/nsp2117M117VAtgGtg2929AY.410.008524
ORF1ab/nsp2117M117VAtgGtg2424B.1.617.20.00009
ORF1ab/nsp2117M117VAtgGtg2020B.1.1.70.000018
ORF1ab/nsp2117M117VAtgGtg1818P.10.000284
ORF1ab/nsp2117M117VAtgGtg1313B.1.438.31
ORF1ab/nsp2117M117VAtgGtg1212AY.1030.000075
ORF1ab/nsp2117M117VAtgGtg1011AY.430.000044
ORF1ab/nsp2117M117VAtGGtC111AY.430.000004
ORF1ab/nsp2117M117VAtgGtg1111AY.440.000067
ORF1ab/nsp2117M117VAtgGtg1010B.1.20.000088
ORF1ab/nsp2117M117VAtgGtg1010B.1.2430.000696
ORF1ab/nsp2117M117VAtgGtg99B.1.4290.000212
ORF1ab/nsp2117M117VAtgGtg88AY.30.00008
ORF1ab/nsp2117M117VAtgGtg77AY.1180.000439
ORF1ab/nsp2117M117VAtgGtg55AY.1020.000133
ORF1ab/nsp2117M117VAtgGtg55AY.200.000194
ORF1ab/nsp2117M117VAtgGtg55AY.290.000079
ORF1ab/nsp2117M117VAtgGtg55B.1.3110.001373
ORF1ab/nsp2117M117VAtgGtg44AY.260.000113
ORF1ab/nsp2117M117VAtgGtg44B.1.2210.000284
ORF1ab/nsp2117M117VAtgGtg44B.1.4270.000202
ORF1ab/nsp2117M117VAtgGtg33AY.250.000018
ORF1ab/nsp2117M117VAtgGtg33AY.390.000074
ORF1ab/nsp2117M117VAtgGtg33B.1.1.630.001157
ORF1ab/nsp2117M117VAtgGtg33B.1.2340.000396
ORF1ab/nsp2117M117VAtgGtg33B.1.4680.017143
ORF1ab/nsp2117M117VAtgGtg33B.1.5250.000339
ORF1ab/nsp2117M117VAtgGtg33C.370.000348
ORF1ab/nsp2117M117VAtgGtg22AY.1190.000071
ORF1ab/nsp2117M117VAtgGtg22AY.340.000194
ORF1ab/nsp2117M117VAtgGtg22AY.4.40.000818
ORF1ab/nsp2117M117VAtgGtg22AY.710.00095
ORF1ab/nsp2117M117VAtgGtg22AY.98.10.000097
ORF1ab/nsp2117M117VAtGGtT12B.1.10.000018
ORF1ab/nsp2117M117VAtgGtg12B.1.10.000018
ORF1ab/nsp2117M117VAtgGtg22B.1.1600.000062
ORF1ab/nsp2117M117VAtgGtg22B.1.3670.001585
ORF1ab/nsp2117M117VAtgGtg22B.1.466.20.000782
ORF1ab/nsp2117M117VAtgGtg22B.1.5960.000174
ORF1ab/nsp2117M117VAtgGtg22B.1.6370.000146
ORF1ab/nsp2117M117VAtgGtg11A0.000387
ORF1ab/nsp2117M117VAtgGtg11A.280.002646
ORF1ab/nsp2117M117VAtgGtg11AY.140.000088
ORF1ab/nsp2117M117VAtgGtg11AY.4.50.000107
ORF1ab/nsp2117M117VAtgGtg11AY.460.000104
ORF1ab/nsp2117M117VAtgGtg11AY.470.000031
ORF1ab/nsp2117M117VAtgGtg11AY.610.000105
ORF1ab/nsp2117M117VAtgGtg11AY.690.000187
ORF1ab/nsp2117M117VAtgGtg11AY.750.000056
ORF1ab/nsp2117M117VAtgGtg11AY.90.000068
ORF1ab/nsp2117M117VAtgGtg11AY.9.10.000084
ORF1ab/nsp2117M117VAtgGtg11AY.980.000079
ORF1ab/nsp2117M117VAtgGtg11B.1.1.1940.00495
ORF1ab/nsp2117M117VAtgGtg11B.1.1.3650.005587
ORF1ab/nsp2117M117VAtgGtg11B.1.1.3670.055556
ORF1ab/nsp2117M117VAtgGtg11B.1.1.4200.001006
ORF1ab/nsp2117M117VAtgGtg11B.1.1.5190.00004
ORF1ab/nsp2117M117VAtgGtg11B.1.177.730.000566
ORF1ab/nsp2117M117VAtgGtg11B.1.2270.047619
ORF1ab/nsp2117M117VAtgGtg11B.1.3510.00003
ORF1ab/nsp2117M117VAtgGtg11B.1.351.20.000303
ORF1ab/nsp2117M117VAtgGtg11B.1.3960.000706
ORF1ab/nsp2117M117VAtgGtg11B.1.4390.005917
ORF1ab/nsp2117M117VAtgGtg11B.1.5130.013889
ORF1ab/nsp2117M117VAtgGtg11B.1.5260.000024
ORF1ab/nsp2117M117VAtgGtg11B.1.5610.000397
ORF1ab/nsp2117M117VAtgGtg11B.1.6180.004032
ORF1ab/nsp2117M117VAtgGtg11P.1.140.000048

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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