CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = L567L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2567L567LL747LsynctTctC3192490.7805642504-2506
ORF1ab/nsp2567L567LL747LsynctTctG319570.1786832504-2506
ORF1ab/nsp2567L567LL747LsynctTctA319130.04075242504-2506

Details of the mutation L567L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2567L567LctTctC249319All0.000048
ORF1ab/nsp2567L567LctTctG57319All0.000011
ORF1ab/nsp2567L567LctTctA13319All0.000002
ORF1ab/nsp2567L567LctTctC5050AY.39.10.001981
ORF1ab/nsp2567L567LctTctC4750B.1.1.70.000042
ORF1ab/nsp2567L567LctTctA350B.1.1.70.000003
ORF1ab/nsp2567L567LctTctG2432B.1.617.20.00009
ORF1ab/nsp2567L567LctTctC732B.1.617.20.000026
ORF1ab/nsp2567L567LctTctA132B.1.617.20.000004
ORF1ab/nsp2567L567LctTctC2021P.10.000315
ORF1ab/nsp2567L567LctTctG121P.10.000016
ORF1ab/nsp2567L567LctTctC1618AY.40.000025
ORF1ab/nsp2567L567LctTctG218AY.40.000003
ORF1ab/nsp2567L567LctTctC1315B.1.10.000236
ORF1ab/nsp2567L567LctTctG215B.1.10.000036
ORF1ab/nsp2567L567LctTctG1414AY.630.005416
ORF1ab/nsp2567L567LctTctC1111B.1.20.000097
ORF1ab/nsp2567L567LctTctC1111B.1.36.170.005435
ORF1ab/nsp2567L567LctTctC77AY.250.000042
ORF1ab/nsp2567L567LctTctG46AY.440.000024
ORF1ab/nsp2567L567LctTctC26AY.440.000012
ORF1ab/nsp2567L567LctTctC56B.1.1770.000066
ORF1ab/nsp2567L567LctTctG16B.1.1770.000013
ORF1ab/nsp2567L567LctTctC25B.1.3510.000059
ORF1ab/nsp2567L567LctTctG25B.1.3510.000059
ORF1ab/nsp2567L567LctTctA15B.1.3510.00003
ORF1ab/nsp2567L567LctTctC44AY.4.50.00043
ORF1ab/nsp2567L567LctTctC34AY.430.000013
ORF1ab/nsp2567L567LctTctG14AY.430.000004
ORF1ab/nsp2567L567LctTctC44B.1.1.540.012085
ORF1ab/nsp2567L567LctTctC44B.1.1600.000125
ORF1ab/nsp2567L567LctTctC33AY.1200.000112
ORF1ab/nsp2567L567LctTctG23AY.30.00002
ORF1ab/nsp2567L567LctTctC13AY.30.00001
ORF1ab/nsp2567L567LctTctC23B.10.000018
ORF1ab/nsp2567L567LctTctA13B.10.000009
ORF1ab/nsp2567L567LctTctC33B.1.160.280.008772
ORF1ab/nsp2567L567LctTctA22AY.1030.000012
ORF1ab/nsp2567L567LctTctC22AY.260.000057
ORF1ab/nsp2567L567LctTctC22AY.390.000049
ORF1ab/nsp2567L567LctTctA22AY.46.40.000329
ORF1ab/nsp2567L567LctTctC22AY.470.000062
ORF1ab/nsp2567L567LctTctC22AY.600.001876
ORF1ab/nsp2567L567LctTctA22B.1.1.3370.007194
ORF1ab/nsp2567L567LctTctC22B.1.4290.000047
ORF1ab/nsp2567L567LctTctC11A.2.20.001689
ORF1ab/nsp2567L567LctTctA11AS.10.009524
ORF1ab/nsp2567L567LctTctG11AY.1140.000231
ORF1ab/nsp2567L567LctTctC11AY.130.000161
ORF1ab/nsp2567L567LctTctC11AY.160.00038
ORF1ab/nsp2567L567LctTctC11AY.420.00004
ORF1ab/nsp2567L567LctTctG11AY.700.000209
ORF1ab/nsp2567L567LctTctC11AY.840.000437
ORF1ab/nsp2567L567LctTctC11AY.980.000079
ORF1ab/nsp2567L567LctTctC11AY.99.20.000092
ORF1ab/nsp2567L567LctTctC11B.1.1.10.000327
ORF1ab/nsp2567L567LctTctG11B.1.1.1940.00495
ORF1ab/nsp2567L567LctTctC11B.1.1.3720.000689
ORF1ab/nsp2567L567LctTctC11B.1.1.4170.002703
ORF1ab/nsp2567L567LctTctC11B.1.1.5190.00004
ORF1ab/nsp2567L567LctTctG11B.1.1100.004525
ORF1ab/nsp2567L567LctTctC11B.1.1700.00431
ORF1ab/nsp2567L567LctTctC11B.1.177.100.000878
ORF1ab/nsp2567L567LctTctC11B.1.177.400.005155
ORF1ab/nsp2567L567LctTctC11B.1.2340.000132
ORF1ab/nsp2567L567LctTctC11B.1.2410.000812
ORF1ab/nsp2567L567LctTctC11B.1.3110.000275
ORF1ab/nsp2567L567LctTctC11B.1.4270.00005
ORF1ab/nsp2567L567LctTctC11B.1.5770.000687
ORF1ab/nsp2567L567LctTctC11B.1.5820.000491
ORF1ab/nsp2567L567LctTctC11B.1.617.10.000129
ORF1ab/nsp2567L567LctTctC11B.30.000831
ORF1ab/nsp2567L567LctTctC11C.370.000116
ORF1ab/nsp2567L567LctTctC11P.1.160.000374

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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