CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = L567F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2567L567FL747FnonsynCttTtt7147130.9985992504-2506
ORF1ab/nsp2567L567FL747FnonsynCtTTtC71410.001400562504-2506

Details of the mutation L567F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2567L567FCttTtt713714All0.000136
ORF1ab/nsp2567L567FCtTTtC1714All0
ORF1ab/nsp2567L567FCttTtt133133AY.30.001323
ORF1ab/nsp2567L567FCttTtt115115B.1.1.70.000103
ORF1ab/nsp2567L567FCttTtt108108AY.440.000657
ORF1ab/nsp2567L567FCttTtt7575AY.46.60.005416
ORF1ab/nsp2567L567FCttTtt4040AY.40.000062
ORF1ab/nsp2567L567FCttTtt2425B.1.20.000211
ORF1ab/nsp2567L567FCtTTtC125B.1.20.000009
ORF1ab/nsp2567L567FCttTtt1818B.1.4290.000424
ORF1ab/nsp2567L567FCttTtt1818B.1.617.20.000068
ORF1ab/nsp2567L567FCttTtt1010B.1.4990.010504
ORF1ab/nsp2567L567FCttTtt1010P.10.000158
ORF1ab/nsp2567L567FCttTtt1010P.1.100.002695
ORF1ab/nsp2567L567FCttTtt99AY.250.000054
ORF1ab/nsp2567L567FCttTtt99AY.430.00004
ORF1ab/nsp2567L567FCttTtt88B.10.000073
ORF1ab/nsp2567L567FCttTtt88B.1.1770.000105
ORF1ab/nsp2567L567FCttTtt77AY.7.10.000789
ORF1ab/nsp2567L567FCttTtt66AY.9.10.000502
ORF1ab/nsp2567L567FCttTtt66B.1.466.20.002347
ORF1ab/nsp2567L567FCttTtt66B.1.499.10.666667
ORF1ab/nsp2567L567FCttTtt55B.1.10.000091
ORF1ab/nsp2567L567FCttTtt55B.1.1.1890.007564
ORF1ab/nsp2567L567FCttTtt44AY.1000.000184
ORF1ab/nsp2567L567FCttTtt44B.1.5260.000094
ORF1ab/nsp2567L567FCttTtt44P.1.150.000929
ORF1ab/nsp2567L567FCttTtt33AY.1190.000106
ORF1ab/nsp2567L567FCttTtt33AY.540.000286
ORF1ab/nsp2567L567FCttTtt33AY.920.000862
ORF1ab/nsp2567L567FCttTtt33B.1.2400.000647
ORF1ab/nsp2567L567FCttTtt22AY.1030.000012
ORF1ab/nsp2567L567FCttTtt22AY.160.000759
ORF1ab/nsp2567L567FCttTtt22AY.200.000078
ORF1ab/nsp2567L567FCttTtt22B.1.1.280.000622
ORF1ab/nsp2567L567FCttTtt22B.1.1.5190.000079
ORF1ab/nsp2567L567FCttTtt22B.1.2580.000133
ORF1ab/nsp2567L567FCttTtt22B.1.3510.000059
ORF1ab/nsp2567L567FCttTtt22B.1.360.000292
ORF1ab/nsp2567L567FCttTtt22B.6.60.001778
ORF1ab/nsp2567L567FCttTtt11A0.000387
ORF1ab/nsp2567L567FCttTtt11AU.30.00211
ORF1ab/nsp2567L567FCttTtt11AY.10.000396
ORF1ab/nsp2567L567FCttTtt11AY.1010.00049
ORF1ab/nsp2567L567FCttTtt11AY.1020.000027
ORF1ab/nsp2567L567FCttTtt11AY.1170.000085
ORF1ab/nsp2567L567FCttTtt11AY.1210.000135
ORF1ab/nsp2567L567FCttTtt11AY.260.000028
ORF1ab/nsp2567L567FCttTtt11AY.330.000067
ORF1ab/nsp2567L567FCttTtt11AY.39.10.00004
ORF1ab/nsp2567L567FCttTtt11AY.4.20.000022
ORF1ab/nsp2567L567FCttTtt11AY.420.00004
ORF1ab/nsp2567L567FCttTtt11AY.450.000122
ORF1ab/nsp2567L567FCttTtt11AY.46.50.000198
ORF1ab/nsp2567L567FCttTtt11AY.470.000031
ORF1ab/nsp2567L567FCttTtt11AY.580.000907
ORF1ab/nsp2567L567FCttTtt11AY.60.000041
ORF1ab/nsp2567L567FCttTtt11AY.610.000105
ORF1ab/nsp2567L567FCttTtt11AY.680.000274
ORF1ab/nsp2567L567FCttTtt11AY.750.000056
ORF1ab/nsp2567L567FCttTtt11B.1.1.2140.000055
ORF1ab/nsp2567L567FCttTtt11B.1.1.390.00051
ORF1ab/nsp2567L567FCttTtt11B.1.1.430.014925
ORF1ab/nsp2567L567FCttTtt11B.1.1.630.000386
ORF1ab/nsp2567L567FCttTtt11B.1.1470.000756
ORF1ab/nsp2567L567FCttTtt11B.1.1600.000031
ORF1ab/nsp2567L567FCttTtt11B.1.160.300.002976
ORF1ab/nsp2567L567FCttTtt11B.1.177.650.000665
ORF1ab/nsp2567L567FCttTtt11B.1.1990.004132
ORF1ab/nsp2567L567FCttTtt11B.1.2210.000071
ORF1ab/nsp2567L567FCttTtt11B.1.3670.000792
ORF1ab/nsp2567L567FCttTtt11B.1.4270.00005
ORF1ab/nsp2567L567FCttTtt11B.1.4710.002732
ORF1ab/nsp2567L567FCttTtt11B.1.5330.009615
ORF1ab/nsp2567L567FCttTtt11B.1.617.10.000129
ORF1ab/nsp2567L567FCttTtt11B.1.6210.000089
ORF1ab/nsp2567L567FCttTtt11C.370.000116
ORF1ab/nsp2567L567FCttTtt11D.20.000075
ORF1ab/nsp2567L567FCttTtt11L.30.003546
ORF1ab/nsp2567L567FCttTtt11P.1.140.000048
ORF1ab/nsp2567L567FCttTtt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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