CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = K81N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp281K81NK261NnonsynaaGaaT1232691232490.9998381046-1048
ORF1ab/nsp281K81NK261NnonsynaaGaaC123269200.0001622471046-1048

Details of the mutation K81N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp281K81NaaGaaT123249123269All0.023573
ORF1ab/nsp281K81NaaGaaC20123269All0.000004
ORF1ab/nsp281K81NaaGaaT6365863663B.1.617.20.239699
ORF1ab/nsp281K81NaaGaaC563663B.1.617.20.000019
ORF1ab/nsp281K81NaaGaaT3970539710AY.430.175912
ORF1ab/nsp281K81NaaGaaC539710AY.430.000022
ORF1ab/nsp281K81NaaGaaT32253226AY.440.01963
ORF1ab/nsp281K81NaaGaaC13226AY.440.000006
ORF1ab/nsp281K81NaaGaaT30443044AY.120.962073
ORF1ab/nsp281K81NaaGaaT29492950AY.390.072874
ORF1ab/nsp281K81NaaGaaC12950AY.390.000025
ORF1ab/nsp281K81NaaGaaT15311533AY.1020.040593
ORF1ab/nsp281K81NaaGaaC21533AY.1020.000053
ORF1ab/nsp281K81NaaGaaT12021202AY.460.125104
ORF1ab/nsp281K81NaaGaaT652652AY.1110.119414
ORF1ab/nsp281K81NaaGaaT506506AY.1030.003142
ORF1ab/nsp281K81NaaGaaT480480AY.1190.016948
ORF1ab/nsp281K81NaaGaaT403403AY.5.40.111511
ORF1ab/nsp281K81NaaGaaT331331AY.230.023087
ORF1ab/nsp281K81NaaGaaT274274AY.34.10.139725
ORF1ab/nsp281K81NaaGaaT264264AY.1170.022312
ORF1ab/nsp281K81NaaGaaT260260AY.1160.074563
ORF1ab/nsp281K81NaaGaaT235235AY.5.30.079285
ORF1ab/nsp281K81NaaGaaT229229AY.50.004729
ORF1ab/nsp281K81NaaGaaT206206AY.840.090114
ORF1ab/nsp281K81NaaGaaT183183AY.330.01222
ORF1ab/nsp281K81NaaGaaT173174AY.450.021051
ORF1ab/nsp281K81NaaGaaC1174AY.450.000122
ORF1ab/nsp281K81NaaGaaT165165AY.40.000257
ORF1ab/nsp281K81NaaGaaT150150AY.410.044092
ORF1ab/nsp281K81NaaGaaT136136AY.920.039069
ORF1ab/nsp281K81NaaGaaT130130AY.590.068856
ORF1ab/nsp281K81NaaGaaT126126AY.320.067093
ORF1ab/nsp281K81NaaGaaT116116B.1.1.70.000104
ORF1ab/nsp281K81NaaGaaT114114AY.46.60.008232
ORF1ab/nsp281K81NaaGaaT104104AY.990.109129
ORF1ab/nsp281K81NaaGaaT9999AY.630.038298
ORF1ab/nsp281K81NaaGaaT9292AY.1060.03081
ORF1ab/nsp281K81NaaGaaT8888AY.1050.056592
ORF1ab/nsp281K81NaaGaaT8484AY.1130.011961
ORF1ab/nsp281K81NaaGaaT8484AY.1180.005262
ORF1ab/nsp281K81NaaGaaT8484AY.980.006636
ORF1ab/nsp281K81NaaGaaT8181AY.420.003259
ORF1ab/nsp281K81NaaGaaT7777AY.580.069873
ORF1ab/nsp281K81NaaGaaT7676AY.200.002954
ORF1ab/nsp281K81NaaGaaT7474AY.100.039216
ORF1ab/nsp281K81NaaGaaT7474AY.950.056317
ORF1ab/nsp281K81NaaGaaT7070AY.250.000421
ORF1ab/nsp281K81NaaGaaT6767AY.890.328431
ORF1ab/nsp281K81NaaGaaT6262AY.750.003473
ORF1ab/nsp281K81NaaGaaT5656AY.780.086287
ORF1ab/nsp281K81NaaGaaT5656AY.880.049514
ORF1ab/nsp281K81NaaGaaT5555AY.470.001711
ORF1ab/nsp281K81NaaGaaT5454AY.190.061574
ORF1ab/nsp281K81NaaGaaT5353AY.1210.007172
ORF1ab/nsp281K81NaaGaaT5151B.10.000467
ORF1ab/nsp281K81NaaGaaT4848AY.1000.002208
ORF1ab/nsp281K81NaaGaaT4848AY.98.10.002325
ORF1ab/nsp281K81NaaGaaT4343AY.1080.047409
ORF1ab/nsp281K81NaaGaaT4343AY.1200.001599
ORF1ab/nsp281K81NaaGaaT4343AY.560.069021
ORF1ab/nsp281K81NaaGaaT4343B.1.1.2140.002385
ORF1ab/nsp281K81NaaGaaT4141AY.46.10.042094
ORF1ab/nsp281K81NaaGaaT4141AY.670.019034
ORF1ab/nsp281K81NaaGaaT3838AY.530.010926
ORF1ab/nsp281K81NaaGaaT3535AY.770.039459
ORF1ab/nsp281K81NaaGaaT3535AY.910.025566
ORF1ab/nsp281K81NaaGaaT3434AY.140.002992
ORF1ab/nsp281K81NaaGaaT3434AY.640.020238
ORF1ab/nsp281K81NaaGaaT3030AY.680.008212
ORF1ab/nsp281K81NaaGaaT2727AY.1140.00624
ORF1ab/nsp281K81NaaGaaT2727AY.4.50.002902
ORF1ab/nsp281K81NaaGaaT2525AY.870.020816
ORF1ab/nsp281K81NaaGaaT2323AY.520.01873
ORF1ab/nsp281K81NaaGaaT2020AY.46.20.012706
ORF1ab/nsp281K81NaaGaaT2020AY.740.002313
ORF1ab/nsp281K81NaaGaaT1919AY.600.017824
ORF1ab/nsp281K81NaaGaaT1818AY.1090.013314
ORF1ab/nsp281K81NaaGaaT1818AY.110.024096
ORF1ab/nsp281K81NaaGaaT1717AY.39.10.000673
ORF1ab/nsp281K81NaaGaaT1717AY.4.30.01431
ORF1ab/nsp281K81NaaGaaT1717AY.480.007907
ORF1ab/nsp281K81NaaGaaT1515AY.340.001454
ORF1ab/nsp281K81NaaGaaT1515AY.80.009091
ORF1ab/nsp281K81NaaGaaT1515AY.9.20.000551
ORF1ab/nsp281K81NaaGaaT1414AY.350.003263
ORF1ab/nsp281K81NaaGaaT1414AY.820.018996
ORF1ab/nsp281K81NaaGaaT1414B0.001789
ORF1ab/nsp281K81NaaGaaT1313AY.1010.006376
ORF1ab/nsp281K81NaaGaaT1313AY.75.10.002344
ORF1ab/nsp281K81NaaGaaT1212AY.960.024896
ORF1ab/nsp281K81NaaGaaT1212B.1.3510.000357
ORF1ab/nsp281K81NaaGaaT1111AY.30.000109
ORF1ab/nsp281K81NaaGaaT1111B.1.10.0002
ORF1ab/nsp281K81NaaGaaT1010AY.10.003957
ORF1ab/nsp281K81NaaGaaT1010AY.400.009643
ORF1ab/nsp281K81NaaGaaT1010AY.540.000953
ORF1ab/nsp281K81NaaGaaT1010AY.690.001867
ORF1ab/nsp281K81NaaGaaT1010AY.99.10.015528
ORF1ab/nsp281K81NaaGaaT1010AY.99.20.000922
ORF1ab/nsp281K81NaaGaaT88AY.210.01518
ORF1ab/nsp281K81NaaGaaT88AY.620.003486
ORF1ab/nsp281K81NaaGaaT88AY.860.006639
ORF1ab/nsp281K81NaaGaaT88B.1.4040.010417
ORF1ab/nsp281K81NaaGaaT77AY.1100.000789
ORF1ab/nsp281K81NaaGaaT77AY.370.002212
ORF1ab/nsp281K81NaaGaaT77AY.39.1.10.005072
ORF1ab/nsp281K81NaaGaaT77AY.4.40.002864
ORF1ab/nsp281K81NaaGaaT77N.30.040698
ORF1ab/nsp281K81NaaGaaT66AY.4.2.10.000894
ORF1ab/nsp281K81NaaGaaT66AY.610.000629
ORF1ab/nsp281K81NaaGaaT66AY.850.002563
ORF1ab/nsp281K81NaaGaaT66C.36.30.003403
ORF1ab/nsp281K81NaaGaaT55AY.130.000805
ORF1ab/nsp281K81NaaGaaT55AY.160.001898
ORF1ab/nsp281K81NaaGaaT55AY.90.000338
ORF1ab/nsp281K81NaaGaaT55B.1.177.570.001405
ORF1ab/nsp281K81NaaGaaC55B.1.6210.000443
ORF1ab/nsp281K81NaaGaaT55P.10.000079
ORF1ab/nsp281K81NaaGaaT44AY.4.20.000087
ORF1ab/nsp281K81NaaGaaT44AY.570.002625
ORF1ab/nsp281K81NaaGaaT44AY.70.000784
ORF1ab/nsp281K81NaaGaaT44AY.700.000834
ORF1ab/nsp281K81NaaGaaT44B.1.20.000035
ORF1ab/nsp281K81NaaGaaT33AY.120.10.000963
ORF1ab/nsp281K81NaaGaaT33AY.260.000085
ORF1ab/nsp281K81NaaGaaT33AY.29.10.000662
ORF1ab/nsp281K81NaaGaaT33AY.490.009585
ORF1ab/nsp281K81NaaGaaT33AY.720.004082
ORF1ab/nsp281K81NaaGaaT33AY.9.10.000251
ORF1ab/nsp281K81NaaGaaT33AY.930.000819
ORF1ab/nsp281K81NaaGaaT33AY.940.001328
ORF1ab/nsp281K81NaaGaaT33B.1.2580.0002
ORF1ab/nsp281K81NaaGaaT33P.1.20.003468
ORF1ab/nsp281K81NaaGaaT22AY.1070.000932
ORF1ab/nsp281K81NaaGaaT22AY.500.001599
ORF1ab/nsp281K81NaaGaaT22AY.60.000082
ORF1ab/nsp281K81NaaGaaT22AY.900.001369
ORF1ab/nsp281K81NaaGaaT22AY.970.003401
ORF1ab/nsp281K81NaaGaaT22B.1.1.2160.001781
ORF1ab/nsp281K81NaaGaaT22B.1.1.3360.033333
ORF1ab/nsp281K81NaaGaaT22B.1.1.4480.004065
ORF1ab/nsp281K81NaaGaaT22B.1.4710.005464
ORF1ab/nsp281K81NaaGaaT22B.1.5950.000522
ORF1ab/nsp281K81NaaGaaT22B.1.5960.000174
ORF1ab/nsp281K81NaaGaaT22P.1.80.009569
ORF1ab/nsp281K81NaaGaaT11A.2.50.000499
ORF1ab/nsp281K81NaaGaaT11AY.1040.001984
ORF1ab/nsp281K81NaaGaaT11AY.16.10.00047
ORF1ab/nsp281K81NaaGaaT11AY.170.008197
ORF1ab/nsp281K81NaaGaaT11AY.220.002092
ORF1ab/nsp281K81NaaGaaT11AY.290.000016
ORF1ab/nsp281K81NaaGaaT11AY.360.000148
ORF1ab/nsp281K81NaaGaaT11AY.380.000499
ORF1ab/nsp281K81NaaGaaT11AY.46.40.000165
ORF1ab/nsp281K81NaaGaaT11AY.550.000917
ORF1ab/nsp281K81NaaGaaT11AY.660.00107
ORF1ab/nsp281K81NaaGaaT11AY.7.10.000113
ORF1ab/nsp281K81NaaGaaT11AY.7.20.000559
ORF1ab/nsp281K81NaaGaaT11AY.730.000665
ORF1ab/nsp281K81NaaGaaT11AY.830.001724
ORF1ab/nsp281K81NaaGaaT11B.1.1.2220.000204
ORF1ab/nsp281K81NaaGaaT11B.1.1.250.000569
ORF1ab/nsp281K81NaaGaaT11B.1.1.3170.000412
ORF1ab/nsp281K81NaaGaaT11B.1.1.3640.066667
ORF1ab/nsp281K81NaaGaaT11B.1.1.4320.001266
ORF1ab/nsp281K81NaaGaaT11B.1.1.5070.008696
ORF1ab/nsp281K81NaaGaaT11B.1.1.5190.00004
ORF1ab/nsp281K81NaaGaaT11B.1.1.5230.001563
ORF1ab/nsp281K81NaaGaaT11B.1.1390.000733
ORF1ab/nsp281K81NaaGaaT11B.1.1420.002899
ORF1ab/nsp281K81NaaGaaT11B.1.1770.000013
ORF1ab/nsp281K81NaaGaaT11B.1.177.150.000631
ORF1ab/nsp281K81NaaGaaT11B.1.177.600.000218
ORF1ab/nsp281K81NaaGaaT11B.1.177.730.000566
ORF1ab/nsp281K81NaaGaaT11B.1.2430.00007
ORF1ab/nsp281K81NaaGaaT11B.1.258.140.00098
ORF1ab/nsp281K81NaaGaaT11B.1.258.40.003448
ORF1ab/nsp281K81NaaGaaT11B.1.36.180.00042
ORF1ab/nsp281K81NaaGaaT11B.1.3620.001541
ORF1ab/nsp281K81NaaGaaT11B.1.3890.001002
ORF1ab/nsp281K81NaaGaaT11B.1.4090.000781
ORF1ab/nsp281K81NaaGaaT11B.1.4160.001269
ORF1ab/nsp281K81NaaGaaT11B.1.4290.000024
ORF1ab/nsp281K81NaaGaaT11B.1.5250.000113
ORF1ab/nsp281K81NaaGaaT11B.1.5260.000024
ORF1ab/nsp281K81NaaGaaT11B.1.5990.00365
ORF1ab/nsp281K81NaaGaaT11B.1.6230.000536
ORF1ab/nsp281K81NaaGaaT11B.1.6370.000073
ORF1ab/nsp281K81NaaGaaT11B.550.00295
ORF1ab/nsp281K81NaaGaaT11B.60.00091
ORF1ab/nsp281K81NaaGaaT11C.370.000116
ORF1ab/nsp281K81NaaGaaT11P.1.140.000048
ORF1ab/nsp281K81NaaGaaT11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.