CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = K534K

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2534K534KK714KsynaaGaaA4756475612405-2407

Details of the mutation K534K within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2534K534KaaGaaA47564756All0.00091
ORF1ab/nsp2534K534KaaGaaA15581558B.1.619.10.999359
ORF1ab/nsp2534K534KaaGaaA11161116B.1.6190.972125
ORF1ab/nsp2534K534KaaGaaA706706AY.1200.026248
ORF1ab/nsp2534K534KaaGaaA416416AY.40.000647
ORF1ab/nsp2534K534KaaGaaA190190AY.250.001143
ORF1ab/nsp2534K534KaaGaaA137137B.1.1.70.000123
ORF1ab/nsp2534K534KaaGaaA7171B.1.617.20.000267
ORF1ab/nsp2534K534KaaGaaA5959AY.440.000359
ORF1ab/nsp2534K534KaaGaaA5858B.10.000531
ORF1ab/nsp2534K534KaaGaaA4646B.1.1.2940.058228
ORF1ab/nsp2534K534KaaGaaA3939AY.140.003432
ORF1ab/nsp2534K534KaaGaaA3737AY.1030.00023
ORF1ab/nsp2534K534KaaGaaA3434AY.1020.000901
ORF1ab/nsp2534K534KaaGaaA2323B.1.351.20.006959
ORF1ab/nsp2534K534KaaGaaA1919P.1.120.009197
ORF1ab/nsp2534K534KaaGaaA1616B.1.6120.04244
ORF1ab/nsp2534K534KaaGaaA1515B.1.4290.000353
ORF1ab/nsp2534K534KaaGaaA1212AY.230.000837
ORF1ab/nsp2534K534KaaGaaA1212AY.390.000297
ORF1ab/nsp2534K534KaaGaaA1212B.1.20.000106
ORF1ab/nsp2534K534KaaGaaA1010B.1.258.170.00104
ORF1ab/nsp2534K534KaaGaaA99B.1.10.000163
ORF1ab/nsp2534K534KaaGaaA88AY.680.00219
ORF1ab/nsp2534K534KaaGaaA88P.10.000126
ORF1ab/nsp2534K534KaaGaaA77AY.270.000453
ORF1ab/nsp2534K534KaaGaaA77AY.430.000031
ORF1ab/nsp2534K534KaaGaaA66AY.1190.000212
ORF1ab/nsp2534K534KaaGaaA66AY.420.000241
ORF1ab/nsp2534K534KaaGaaA66C.160.006363
ORF1ab/nsp2534K534KaaGaaA55AY.50.000103
ORF1ab/nsp2534K534KaaGaaA55B.1.5260.000118
ORF1ab/nsp2534K534KaaGaaA44AY.9.10.000335
ORF1ab/nsp2534K534KaaGaaA44B0.000511
ORF1ab/nsp2534K534KaaGaaA44B.1.1600.000125
ORF1ab/nsp2534K534KaaGaaA33AY.710.001425
ORF1ab/nsp2534K534KaaGaaA33AY.980.000237
ORF1ab/nsp2534K534KaaGaaA33B.1.617.10.000387
ORF1ab/nsp2534K534KaaGaaA33B.1.6210.000266
ORF1ab/nsp2534K534KaaGaaA22AY.1130.000285
ORF1ab/nsp2534K534KaaGaaA22AY.120.20.002571
ORF1ab/nsp2534K534KaaGaaA22AY.260.000057
ORF1ab/nsp2534K534KaaGaaA22AY.30.00002
ORF1ab/nsp2534K534KaaGaaA22AY.320.001065
ORF1ab/nsp2534K534KaaGaaA22AY.550.001835
ORF1ab/nsp2534K534KaaGaaA22AY.60.000082
ORF1ab/nsp2534K534KaaGaaA22AY.650.001066
ORF1ab/nsp2534K534KaaGaaA22AY.9.20.000073
ORF1ab/nsp2534K534KaaGaaA22B.1.1.330.000842
ORF1ab/nsp2534K534KaaGaaA22B.1.1770.000026
ORF1ab/nsp2534K534KaaGaaA22B.1.177.120.000303
ORF1ab/nsp2534K534KaaGaaA22B.1.177.600.000437
ORF1ab/nsp2534K534KaaGaaA22B.1.3510.000059
ORF1ab/nsp2534K534KaaGaaA22B.1.36.180.00084
ORF1ab/nsp2534K534KaaGaaA22B.1.36.80.002
ORF1ab/nsp2534K534KaaGaaA22P.1.150.000465
ORF1ab/nsp2534K534KaaGaaA22P.1.20.002312
ORF1ab/nsp2534K534KaaGaaA22R.10.00018
ORF1ab/nsp2534K534KaaGaaA11A.210.00277
ORF1ab/nsp2534K534KaaGaaA11AY.16.10.00047
ORF1ab/nsp2534K534KaaGaaA11AY.190.00114
ORF1ab/nsp2534K534KaaGaaA11AY.200.000039
ORF1ab/nsp2534K534KaaGaaA11AY.330.000067
ORF1ab/nsp2534K534KaaGaaA11AY.350.000233
ORF1ab/nsp2534K534KaaGaaA11AY.360.000148
ORF1ab/nsp2534K534KaaGaaA11AY.39.10.00004
ORF1ab/nsp2534K534KaaGaaA11AY.5.30.000337
ORF1ab/nsp2534K534KaaGaaA11AY.540.000095
ORF1ab/nsp2534K534KaaGaaA11AY.690.000187
ORF1ab/nsp2534K534KaaGaaA11AY.750.000056
ORF1ab/nsp2534K534KaaGaaA11AY.790.001211
ORF1ab/nsp2534K534KaaGaaA11AY.840.000437
ORF1ab/nsp2534K534KaaGaaA11AY.98.10.000048
ORF1ab/nsp2534K534KaaGaaA11AZ.10.000867
ORF1ab/nsp2534K534KaaGaaA11B.1.1.1610.003534
ORF1ab/nsp2534K534KaaGaaA11B.1.1.2840.000107
ORF1ab/nsp2534K534KaaGaaA11B.1.1.3060.000438
ORF1ab/nsp2534K534KaaGaaA11B.1.1.3180.000302
ORF1ab/nsp2534K534KaaGaaA11B.1.1.3510.002793
ORF1ab/nsp2534K534KaaGaaA11B.1.1.4480.002033
ORF1ab/nsp2534K534KaaGaaA11B.1.1.5190.00004
ORF1ab/nsp2534K534KaaGaaA11B.1.1280.000635
ORF1ab/nsp2534K534KaaGaaA11B.1.1470.000756
ORF1ab/nsp2534K534KaaGaaA11B.1.1590.012195
ORF1ab/nsp2534K534KaaGaaA11B.1.160.90.007194
ORF1ab/nsp2534K534KaaGaaA11B.1.177.440.000519
ORF1ab/nsp2534K534KaaGaaA11B.1.177.730.000566
ORF1ab/nsp2534K534KaaGaaA11B.1.177.820.000477
ORF1ab/nsp2534K534KaaGaaA11B.1.2430.00007
ORF1ab/nsp2534K534KaaGaaA11B.1.2580.000067
ORF1ab/nsp2534K534KaaGaaA11B.1.3050.002151
ORF1ab/nsp2534K534KaaGaaA11B.1.360.000146
ORF1ab/nsp2534K534KaaGaaA11B.1.36.290.000517
ORF1ab/nsp2534K534KaaGaaA11B.1.4740.001901
ORF1ab/nsp2534K534KaaGaaA11B.1.4970.000315
ORF1ab/nsp2534K534KaaGaaA11B.1.5510.00129
ORF1ab/nsp2534K534KaaGaaA11B.1.5610.000397
ORF1ab/nsp2534K534KaaGaaA11B.1.5960.000087
ORF1ab/nsp2534K534KaaGaaA11Q.70.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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