CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = K219R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2219K219RK399RnonsynaAgaGg185318500.9983811460-1462
ORF1ab/nsp2219K219RK399RnonsynaAGaGA185320.001079331460-1462
ORF1ab/nsp2219K219RK399RnonsynAAgCGg185310.0005396651460-1462

Details of the mutation K219R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2219K219RaAgaGg18501853All0.000354
ORF1ab/nsp2219K219RaAGaGA21853All0
ORF1ab/nsp2219K219RAAgCGg11853All0
ORF1ab/nsp2219K219RaAgaGg13001302B.1.1.70.001164
ORF1ab/nsp2219K219RAAgCGg11302B.1.1.70.000001
ORF1ab/nsp2219K219RaAGaGA11302B.1.1.70.000001
ORF1ab/nsp2219K219RaAgaGg8585B.1.617.20.00032
ORF1ab/nsp2219K219RaAgaGg5454B.1.1.2960.981818
ORF1ab/nsp2219K219RaAgaGg5353B.1.10.000961
ORF1ab/nsp2219K219RaAgaGg4242AY.40.000065
ORF1ab/nsp2219K219RaAgaGg3838B.1.6210.003364
ORF1ab/nsp2219K219RaAgaGg2828AY.250.000168
ORF1ab/nsp2219K219RaAgaGg2828AY.430.000124
ORF1ab/nsp2219K219RaAgaGg2525AY.440.000152
ORF1ab/nsp2219K219RaAgaGg1617B.1.20.000141
ORF1ab/nsp2219K219RaAGaGA117B.1.20.000009
ORF1ab/nsp2219K219RaAgaGg1515B.10.000137
ORF1ab/nsp2219K219RaAgaGg1313AY.4.20.000282
ORF1ab/nsp2219K219RaAgaGg1313B.1.4290.000306
ORF1ab/nsp2219K219RaAgaGg1212AY.30.000119
ORF1ab/nsp2219K219RaAgaGg1212AY.390.000297
ORF1ab/nsp2219K219RaAgaGg1010B.1.5260.000235
ORF1ab/nsp2219K219RaAgaGg66B.1.1770.000079
ORF1ab/nsp2219K219RaAgaGg55AY.50.000103
ORF1ab/nsp2219K219RaAgaGg55B.1.1.2320.009074
ORF1ab/nsp2219K219RaAgaGg44AY.1030.000025
ORF1ab/nsp2219K219RaAgaGg44AY.1200.000149
ORF1ab/nsp2219K219RaAgaGg44AY.920.001149
ORF1ab/nsp2219K219RaAgaGg44P.10.000063
ORF1ab/nsp2219K219RaAgaGg33AY.9.20.00011
ORF1ab/nsp2219K219RaAgaGg33C.360.002732
ORF1ab/nsp2219K219RaAgaGg33C.370.000348
ORF1ab/nsp2219K219RaAgaGg22AY.1020.000053
ORF1ab/nsp2219K219RaAgaGg22AY.1190.000071
ORF1ab/nsp2219K219RaAgaGg22AY.120.000632
ORF1ab/nsp2219K219RaAgaGg22AY.160.000759
ORF1ab/nsp2219K219RaAgaGg22AY.200.000078
ORF1ab/nsp2219K219RaAgaGg22AY.260.000057
ORF1ab/nsp2219K219RaAgaGg22AY.370.000632
ORF1ab/nsp2219K219RaAgaGg22AY.46.40.000329
ORF1ab/nsp2219K219RaAgaGg22B.1.1600.000062
ORF1ab/nsp2219K219RaAgaGg22B.1.177.500.00939
ORF1ab/nsp2219K219RaAgaGg22B.1.2580.000133
ORF1ab/nsp2219K219RaAgaGg22B.1.3510.000059
ORF1ab/nsp2219K219RaAgaGg22B.1.4270.000101
ORF1ab/nsp2219K219RaAgaGg22B.1.6230.001073
ORF1ab/nsp2219K219RaAgaGg22B.1.6370.000146
ORF1ab/nsp2219K219RaAgaGg22D.20.00015
ORF1ab/nsp2219K219RaAgaGg11A.20.000662
ORF1ab/nsp2219K219RaAgaGg11AT.10.005128
ORF1ab/nsp2219K219RaAgaGg11AY.1000.000046
ORF1ab/nsp2219K219RaAgaGg11AY.1110.000183
ORF1ab/nsp2219K219RaAgaGg11AY.140.000088
ORF1ab/nsp2219K219RaAgaGg11AY.230.00007
ORF1ab/nsp2219K219RaAgaGg11AY.3.10.000085
ORF1ab/nsp2219K219RaAgaGg11AY.320.000532
ORF1ab/nsp2219K219RaAgaGg11AY.740.000116
ORF1ab/nsp2219K219RaAgaGg11AY.90.000068
ORF1ab/nsp2219K219RaAgaGg11AY.990.001049
ORF1ab/nsp2219K219RaAgaGg11B.1.1.1390.022727
ORF1ab/nsp2219K219RaAgaGg11B.1.1.2160.00089
ORF1ab/nsp2219K219RaAgaGg11B.1.1.280.000311
ORF1ab/nsp2219K219RaAgaGg11B.1.1.3180.000302
ORF1ab/nsp2219K219RaAgaGg11B.1.1.3290.003846
ORF1ab/nsp2219K219RaAgaGg11B.1.1.4090.002833
ORF1ab/nsp2219K219RaAgaGg11B.1.110.30.000718
ORF1ab/nsp2219K219RaAgaGg11B.1.1110.001175
ORF1ab/nsp2219K219RaAgaGg11B.1.177.210.000076
ORF1ab/nsp2219K219RaAgaGg11B.1.177.650.000665
ORF1ab/nsp2219K219RaAgaGg11B.1.177.70.000165
ORF1ab/nsp2219K219RaAgaGg11B.1.2210.000071
ORF1ab/nsp2219K219RaAgaGg11B.1.2370.004975
ORF1ab/nsp2219K219RaAgaGg11B.1.351.30.000876
ORF1ab/nsp2219K219RaAgaGg11B.1.3670.000792
ORF1ab/nsp2219K219RaAgaGg11B.1.3990.001934
ORF1ab/nsp2219K219RaAgaGg11B.1.617.10.000129
ORF1ab/nsp2219K219RaAgaGg11D.50.004975
ORF1ab/nsp2219K219RaAgaGg11P.1.140.000048
ORF1ab/nsp2219K219RaAgaGg11P.1.170.000162
ORF1ab/nsp2219K219RaAgaGg11P.1.70.000319
ORF1ab/nsp2219K219RaAgaGg11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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