CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = K112N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2112K112NK292NnonsynaaGaaT248624420.9823011139-1141
ORF1ab/nsp2112K112NK292NnonsynaaGaaC2486440.01769911139-1141

Details of the mutation K112N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2112K112NaaGaaT24422486All0.000467
ORF1ab/nsp2112K112NaaGaaC442486All0.000008
ORF1ab/nsp2112K112NaaGaaT423423AY.380.211183
ORF1ab/nsp2112K112NaaGaaT283285B.1.1.70.000253
ORF1ab/nsp2112K112NaaGaaC2285B.1.1.70.000002
ORF1ab/nsp2112K112NaaGaaT259259AY.40.000403
ORF1ab/nsp2112K112NaaGaaT235235B.1.214.20.140887
ORF1ab/nsp2112K112NaaGaaT9191B.1.20.000801
ORF1ab/nsp2112K112NaaGaaT7087B.1.617.20.000264
ORF1ab/nsp2112K112NaaGaaC1787B.1.617.20.000064
ORF1ab/nsp2112K112NaaGaaT8282B.1.6310.276094
ORF1ab/nsp2112K112NaaGaaT7777B.1.4290.001812
ORF1ab/nsp2112K112NaaGaaT6060AY.390.001483
ORF1ab/nsp2112K112NaaGaaT5759B.10.000522
ORF1ab/nsp2112K112NaaGaaC259B.10.000018
ORF1ab/nsp2112K112NaaGaaT4949AY.30.000487
ORF1ab/nsp2112K112NaaGaaT4646B.1.2511
ORF1ab/nsp2112K112NaaGaaT4242AY.250.000253
ORF1ab/nsp2112K112NaaGaaT3031AY.430.000133
ORF1ab/nsp2112K112NaaGaaC131AY.430.000004
ORF1ab/nsp2112K112NaaGaaT2727P.10.000425
ORF1ab/nsp2112K112NaaGaaT2626AY.98.10.001259
ORF1ab/nsp2112K112NaaGaaT2526B.1.360.003648
ORF1ab/nsp2112K112NaaGaaC126B.1.360.000146
ORF1ab/nsp2112K112NaaGaaT1725AY.1030.000106
ORF1ab/nsp2112K112NaaGaaC825AY.1030.00005
ORF1ab/nsp2112K112NaaGaaT2225B.1.1770.00029
ORF1ab/nsp2112K112NaaGaaC325B.1.1770.00004
ORF1ab/nsp2112K112NaaGaaT2323P.1.140.001099
ORF1ab/nsp2112K112NaaGaaT2122B.1.10.000381
ORF1ab/nsp2112K112NaaGaaC122B.1.10.000018
ORF1ab/nsp2112K112NaaGaaT2121B.1.1.500.014257
ORF1ab/nsp2112K112NaaGaaT1919B.1.1600.000593
ORF1ab/nsp2112K112NaaGaaT1818AY.1200.000669
ORF1ab/nsp2112K112NaaGaaT1818AY.440.00011
ORF1ab/nsp2112K112NaaGaaT1818B.1.3690.005134
ORF1ab/nsp2112K112NaaGaaT1616AY.5.40.004427
ORF1ab/nsp2112K112NaaGaaT1515Q.30.002175
ORF1ab/nsp2112K112NaaGaaT1313AY.39.10.000515
ORF1ab/nsp2112K112NaaGaaT1212AY.3.10.001023
ORF1ab/nsp2112K112NaaGaaT1111AY.160.004176
ORF1ab/nsp2112K112NaaGaaT1111B.1.1.3110.00394
ORF1ab/nsp2112K112NaaGaaT1010B.1.1.3170.004117
ORF1ab/nsp2112K112NaaGaaT1010B.1.2100.021322
ORF1ab/nsp2112K112NaaGaaT1010B.1.5960.000871
ORF1ab/nsp2112K112NaaGaaT99A.2.50.004491
ORF1ab/nsp2112K112NaaGaaT99AY.1020.000239
ORF1ab/nsp2112K112NaaGaaT99AY.460.000937
ORF1ab/nsp2112K112NaaGaaT99AY.980.000711
ORF1ab/nsp2112K112NaaGaaT99B.1.258.170.000936
ORF1ab/nsp2112K112NaaGaaT88AY.200.000311
ORF1ab/nsp2112K112NaaGaaT88AY.470.000249
ORF1ab/nsp2112K112NaaGaaT88B.1.36.290.004139
ORF1ab/nsp2112K112NaaGaaT67B.1.3510.000178
ORF1ab/nsp2112K112NaaGaaC17B.1.3510.00003
ORF1ab/nsp2112K112NaaGaaT77B.1.4050.08642
ORF1ab/nsp2112K112NaaGaaT66AY.420.000241
ORF1ab/nsp2112K112NaaGaaT66AY.50.000124
ORF1ab/nsp2112K112NaaGaaT55AY.230.000349
ORF1ab/nsp2112K112NaaGaaT45AY.350.000932
ORF1ab/nsp2112K112NaaGaaC15AY.350.000233
ORF1ab/nsp2112K112NaaGaaT55B.1.5260.000118
ORF1ab/nsp2112K112NaaGaaT44AY.1190.000141
ORF1ab/nsp2112K112NaaGaaT44AY.260.000113
ORF1ab/nsp2112K112NaaGaaT44AY.290.000063
ORF1ab/nsp2112K112NaaGaaT44AY.610.000419
ORF1ab/nsp2112K112NaaGaaT44B.1.1.1890.006051
ORF1ab/nsp2112K112NaaGaaT44B.1.1.3620.022472
ORF1ab/nsp2112K112NaaGaaT44B.1.1.5190.000159
ORF1ab/nsp2112K112NaaGaaT44B.1.2580.000266
ORF1ab/nsp2112K112NaaGaaT44B.1.258.110.001585
ORF1ab/nsp2112K112NaaGaaT44B.1.3660.019512
ORF1ab/nsp2112K112NaaGaaT44B.1.621.10.002023
ORF1ab/nsp2112K112NaaGaaT44P.1.120.001936
ORF1ab/nsp2112K112NaaGaaT33AY.1180.000188
ORF1ab/nsp2112K112NaaGaaT33AY.330.0002
ORF1ab/nsp2112K112NaaGaaT33AY.650.001599
ORF1ab/nsp2112K112NaaGaaT23AY.740.000231
ORF1ab/nsp2112K112NaaGaaC13AY.740.000116
ORF1ab/nsp2112K112NaaGaaT33B.1.1.280.000934
ORF1ab/nsp2112K112NaaGaaT33B.1.1.5140.115385
ORF1ab/nsp2112K112NaaGaaT33C.370.000348
ORF1ab/nsp2112K112NaaGaaT33P.1.70.000958
ORF1ab/nsp2112K112NaaGaaC220.111111
ORF1ab/nsp2112K112NaaGaaT22AY.1000.000092
ORF1ab/nsp2112K112NaaGaaT22AY.46.40.000329
ORF1ab/nsp2112K112NaaGaaT22AY.550.001835
ORF1ab/nsp2112K112NaaGaaT22AY.560.00321
ORF1ab/nsp2112K112NaaGaaT22AY.570.001312
ORF1ab/nsp2112K112NaaGaaT22AY.60.000082
ORF1ab/nsp2112K112NaaGaaT22AY.710.00095
ORF1ab/nsp2112K112NaaGaaT22AY.750.000112
ORF1ab/nsp2112K112NaaGaaT22AY.75.10.000361
ORF1ab/nsp2112K112NaaGaaT22AY.880.001768
ORF1ab/nsp2112K112NaaGaaT22B.1.1.100.00223
ORF1ab/nsp2112K112NaaGaaT22B.1.1.2220.000408
ORF1ab/nsp2112K112NaaGaaT22B.1.1.3060.000877
ORF1ab/nsp2112K112NaaGaaT22B.1.1.3760.011905
ORF1ab/nsp2112K112NaaGaaT22B.1.1.570.022989
ORF1ab/nsp2112K112NaaGaaT22B.1.2140.007326
ORF1ab/nsp2112K112NaaGaaT22B.1.2430.000139
ORF1ab/nsp2112K112NaaGaaT22B.1.36.380.003284
ORF1ab/nsp2112K112NaaGaaT22B.1.3620.003082
ORF1ab/nsp2112K112NaaGaaT22B.1.466.20.000782
ORF1ab/nsp2112K112NaaGaaT22B.1.5950.000522
ORF1ab/nsp2112K112NaaGaaT22C.36.30.001134
ORF1ab/nsp2112K112NaaGaaT22D.20.00015
ORF1ab/nsp2112K112NaaGaaT22R.10.00018
ORF1ab/nsp2112K112NaaGaaT11A0.000387
ORF1ab/nsp2112K112NaaGaaC11A.20.000662
ORF1ab/nsp2112K112NaaGaaT11A.2.20.001689
ORF1ab/nsp2112K112NaaGaaT11AD.20.000219
ORF1ab/nsp2112K112NaaGaaT11AY.100.00053
ORF1ab/nsp2112K112NaaGaaT11AY.1060.000335
ORF1ab/nsp2112K112NaaGaaT11AY.1130.000142
ORF1ab/nsp2112K112NaaGaaT11AY.1160.000287
ORF1ab/nsp2112K112NaaGaaT11AY.120.20.001285
ORF1ab/nsp2112K112NaaGaaT11AY.1210.000135
ORF1ab/nsp2112K112NaaGaaT11AY.16.10.00047
ORF1ab/nsp2112K112NaaGaaC11AY.300.000396
ORF1ab/nsp2112K112NaaGaaT11AY.340.000097
ORF1ab/nsp2112K112NaaGaaT11AY.4.20.000022
ORF1ab/nsp2112K112NaaGaaT11AY.4.50.000107
ORF1ab/nsp2112K112NaaGaaT11AY.410.000294
ORF1ab/nsp2112K112NaaGaaT11AY.450.000122
ORF1ab/nsp2112K112NaaGaaT11AY.46.60.000072
ORF1ab/nsp2112K112NaaGaaT11AY.7.10.000113
ORF1ab/nsp2112K112NaaGaaT11AY.850.000427
ORF1ab/nsp2112K112NaaGaaT11AY.910.00073
ORF1ab/nsp2112K112NaaGaaT11B0.000128
ORF1ab/nsp2112K112NaaGaaT11B.1.1.2140.000055
ORF1ab/nsp2112K112NaaGaaT11B.1.1.2260.005814
ORF1ab/nsp2112K112NaaGaaT11B.1.1.2280.003049
ORF1ab/nsp2112K112NaaGaaT11B.1.1.2630.001558
ORF1ab/nsp2112K112NaaGaaT11B.1.1.2940.001266
ORF1ab/nsp2112K112NaaGaaT11B.1.1.3590.027778
ORF1ab/nsp2112K112NaaGaaT11B.1.1.540.003021
ORF1ab/nsp2112K112NaaGaaC11B.1.1.710.006061
ORF1ab/nsp2112K112NaaGaaT11B.1.177.320.00135
ORF1ab/nsp2112K112NaaGaaC11B.1.177.70.000165
ORF1ab/nsp2112K112NaaGaaT11B.1.177.860.000183
ORF1ab/nsp2112K112NaaGaaT11B.1.1790.003759
ORF1ab/nsp2112K112NaaGaaT11B.1.2340.000132
ORF1ab/nsp2112K112NaaGaaT11B.1.258.210.007752
ORF1ab/nsp2112K112NaaGaaT11B.1.2600.003344
ORF1ab/nsp2112K112NaaGaaT11B.1.36.220.001208
ORF1ab/nsp2112K112NaaGaaT11B.1.3610.001289
ORF1ab/nsp2112K112NaaGaaT11B.1.3890.001002
ORF1ab/nsp2112K112NaaGaaT11B.1.4700.001404
ORF1ab/nsp2112K112NaaGaaT11B.1.5210.004975
ORF1ab/nsp2112K112NaaGaaT11B.1.5330.009615
ORF1ab/nsp2112K112NaaGaaT11B.1.5640.000426
ORF1ab/nsp2112K112NaaGaaT11B.1.6270.00202
ORF1ab/nsp2112K112NaaGaaT11B.1.6370.000073
ORF1ab/nsp2112K112NaaGaaT11C.10.002392
ORF1ab/nsp2112K112NaaGaaT11P.1.170.000162
ORF1ab/nsp2112K112NaaGaaT11P.1.90.004808
ORF1ab/nsp2112K112NaaGaaT11P.20.000187
ORF1ab/nsp2112K112NaaGaaT11P.30.001595
ORF1ab/nsp2112K112NaaGaaT11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.