CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = I251M

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2251I251MI431MnonsynatAatG4138413811556-1558

Details of the mutation I251M within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2251I251MatAatG41384138All0.000791
ORF1ab/nsp2251I251MatAatG12521252B.1.617.20.004714
ORF1ab/nsp2251I251MatAatG590590AY.400.568949
ORF1ab/nsp2251I251MatAatG323323AY.40.000503
ORF1ab/nsp2251I251MatAatG287287B.1.1770.003779
ORF1ab/nsp2251I251MatAatG275275B.1.1.70.000246
ORF1ab/nsp2251I251MatAatG256256AY.460.026644
ORF1ab/nsp2251I251MatAatG8888B.1.1.2220.017952
ORF1ab/nsp2251I251MatAatG6868B.1.177.40.014352
ORF1ab/nsp2251I251MatAatG5959B.1.10.00107
ORF1ab/nsp2251I251MatAatG5555B.1.4380.359477
ORF1ab/nsp2251I251MatAatG5353AY.620.023094
ORF1ab/nsp2251I251MatAatG4848AY.600.045028
ORF1ab/nsp2251I251MatAatG4747B.10.00043
ORF1ab/nsp2251I251MatAatG4646AY.290.000726
ORF1ab/nsp2251I251MatAatG3333P.1.150.007667
ORF1ab/nsp2251I251MatAatG3232P.10.000504
ORF1ab/nsp2251I251MatAatG2929B.1.1.330.012205
ORF1ab/nsp2251I251MatAatG2929B.1.1.4351
ORF1ab/nsp2251I251MatAatG2929P.20.005412
ORF1ab/nsp2251I251MatAatG2525B.1.20.00022
ORF1ab/nsp2251I251MatAatG2424AY.16.10.011278
ORF1ab/nsp2251I251MatAatG2222B.1.2410.017857
ORF1ab/nsp2251I251MatAatG2121AY.590.011123
ORF1ab/nsp2251I251MatAatG1919B.1.177.341
ORF1ab/nsp2251I251MatAatG1717AY.1030.000106
ORF1ab/nsp2251I251MatAatG1616AY.5.20.039409
ORF1ab/nsp2251I251MatAatG1515B.1.1.3480.011943
ORF1ab/nsp2251I251MatAatG1313AY.260.000368
ORF1ab/nsp2251I251MatAatG1313AY.30.000129
ORF1ab/nsp2251I251MatAatG1313C.370.001509
ORF1ab/nsp2251I251MatAatG1212AY.390.000297
ORF1ab/nsp2251I251MatAatG1212B.1.4270.000606
ORF1ab/nsp2251I251MatAatG1111AY.250.000066
ORF1ab/nsp2251I251MatAatG1010AY.440.000061
ORF1ab/nsp2251I251MatAatG99AY.1020.000239
ORF1ab/nsp2251I251MatAatG99AY.470.00028
ORF1ab/nsp2251I251MatAatG99B.1.2580.000599
ORF1ab/nsp2251I251MatAatG88AY.610.000838
ORF1ab/nsp2251I251MatAatG77AY.540.000667
ORF1ab/nsp2251I251MatAatG77AY.860.005809
ORF1ab/nsp2251I251MatAatG77B.1.258.170.000728
ORF1ab/nsp2251I251MatAatG77B.6.80.057851
ORF1ab/nsp2251I251MatAatG66AY.750.000336
ORF1ab/nsp2251I251MatAatG66B.1.1.2840.000644
ORF1ab/nsp2251I251MatAatG66B.1.5260.000141
ORF1ab/nsp2251I251MatAatG55AY.430.000022
ORF1ab/nsp2251I251MatAatG55AY.450.000608
ORF1ab/nsp2251I251MatAatG55AY.650.002665
ORF1ab/nsp2251I251MatAatG55B.1.1.2140.000277
ORF1ab/nsp2251I251MatAatG55B.1.5960.000436
ORF1ab/nsp2251I251MatAatG44AY.270.000259
ORF1ab/nsp2251I251MatAatG44AY.330.000267
ORF1ab/nsp2251I251MatAatG44AY.9.20.000147
ORF1ab/nsp2251I251MatAatG44AY.98.10.000194
ORF1ab/nsp2251I251MatAatG44B.1.1.2320.00726
ORF1ab/nsp2251I251MatAatG44B.1.1.3180.001207
ORF1ab/nsp2251I251MatAatG44B.1.1.3880.181818
ORF1ab/nsp2251I251MatAatG44B.1.1.4340.001394
ORF1ab/nsp2251I251MatAatG44B.1.1.700.001364
ORF1ab/nsp2251I251MatAatG33AY.1000.000138
ORF1ab/nsp2251I251MatAatG33AY.1210.000406
ORF1ab/nsp2251I251MatAatG33AY.140.000264
ORF1ab/nsp2251I251MatAatG33AY.230.000209
ORF1ab/nsp2251I251MatAatG33AY.4.40.001227
ORF1ab/nsp2251I251MatAatG33AY.75.10.000541
ORF1ab/nsp2251I251MatAatG33AY.990.003148
ORF1ab/nsp2251I251MatAatG33B.1.1.3260.005282
ORF1ab/nsp2251I251MatAatG33B.1.1.4320.003797
ORF1ab/nsp2251I251MatAatG33B.1.1.530.041096
ORF1ab/nsp2251I251MatAatG33B.1.1600.000094
ORF1ab/nsp2251I251MatAatG33B.1.177.820.001432
ORF1ab/nsp2251I251MatAatG33B.1.360.000438
ORF1ab/nsp2251I251MatAatG33B.1.6210.000266
ORF1ab/nsp2251I251MatAatG22A.270.003311
ORF1ab/nsp2251I251MatAatG22AY.1170.000169
ORF1ab/nsp2251I251MatAatG22AY.1190.000071
ORF1ab/nsp2251I251MatAatG22AY.700.000417
ORF1ab/nsp2251I251MatAatG22AY.9.10.000167
ORF1ab/nsp2251I251MatAatG22AY.910.001461
ORF1ab/nsp2251I251MatAatG22B.1.1.2160.001781
ORF1ab/nsp2251I251MatAatG22B.1.1.280.000622
ORF1ab/nsp2251I251MatAatG22B.1.1.3980.006452
ORF1ab/nsp2251I251MatAatG22B.1.1.5190.000079
ORF1ab/nsp2251I251MatAatG22B.1.1.630.000772
ORF1ab/nsp2251I251MatAatG22B.1.1110.00235
ORF1ab/nsp2251I251MatAatG22B.1.177.30.015267
ORF1ab/nsp2251I251MatAatG22B.1.177.860.000367
ORF1ab/nsp2251I251MatAatG22B.1.3770.009132
ORF1ab/nsp2251I251MatAatG22B.1.4280.002041
ORF1ab/nsp2251I251MatAatG22B.1.4290.000047
ORF1ab/nsp2251I251MatAatG22B.1.4590.008163
ORF1ab/nsp2251I251MatAatG22B.1.4700.002809
ORF1ab/nsp2251I251MatAatG22B.1.780.017094
ORF1ab/nsp2251I251MatAatG22B.60.00182
ORF1ab/nsp2251I251MatAatG22P.1.140.000096
ORF1ab/nsp2251I251MatAatG22P.1.170.000324
ORF1ab/nsp2251I251MatAatG11A.2.50.000499
ORF1ab/nsp2251I251MatAatG11AY.100.00053
ORF1ab/nsp2251I251MatAatG11AY.1080.001103
ORF1ab/nsp2251I251MatAatG11AY.1180.000063
ORF1ab/nsp2251I251MatAatG11AY.1200.000037
ORF1ab/nsp2251I251MatAatG11AY.120.10.000321
ORF1ab/nsp2251I251MatAatG11AY.160.00038
ORF1ab/nsp2251I251MatAatG11AY.240.000431
ORF1ab/nsp2251I251MatAatG11AY.370.000316
ORF1ab/nsp2251I251MatAatG11AY.4.20.000022
ORF1ab/nsp2251I251MatAatG11AY.420.00004
ORF1ab/nsp2251I251MatAatG11AY.46.20.000635
ORF1ab/nsp2251I251MatAatG11AY.46.30.000934
ORF1ab/nsp2251I251MatAatG11AY.46.60.000072
ORF1ab/nsp2251I251MatAatG11AY.490.003195
ORF1ab/nsp2251I251MatAatG11AY.500.000799
ORF1ab/nsp2251I251MatAatG11AY.580.000907
ORF1ab/nsp2251I251MatAatG11AY.640.000595
ORF1ab/nsp2251I251MatAatG11AY.670.000464
ORF1ab/nsp2251I251MatAatG11AY.7.10.000113
ORF1ab/nsp2251I251MatAatG11AY.770.001127
ORF1ab/nsp2251I251MatAatG11AY.830.001724
ORF1ab/nsp2251I251MatAatG11AY.870.000833
ORF1ab/nsp2251I251MatAatG11AY.90.000068
ORF1ab/nsp2251I251MatAatG11AY.920.000287
ORF1ab/nsp2251I251MatAatG11AY.980.000079
ORF1ab/nsp2251I251MatAatG11AY.99.20.000092
ORF1ab/nsp2251I251MatAatG11B.1.1.10.000327
ORF1ab/nsp2251I251MatAatG11B.1.1.3060.000438
ORF1ab/nsp2251I251MatAatG11B.1.1.3170.000412
ORF1ab/nsp2251I251MatAatG11B.1.1.3710.010417
ORF1ab/nsp2251I251MatAatG11B.1.1.4000.05
ORF1ab/nsp2251I251MatAatG11B.1.1.4140.142857
ORF1ab/nsp2251I251MatAatG11B.1.1.4200.001006
ORF1ab/nsp2251I251MatAatG11B.1.1.830.00271
ORF1ab/nsp2251I251MatAatG11B.1.160.150.00495
ORF1ab/nsp2251I251MatAatG11B.1.177.160.000664
ORF1ab/nsp2251I251MatAatG11B.1.177.350.000691
ORF1ab/nsp2251I251MatAatG11B.1.177.430.001477
ORF1ab/nsp2251I251MatAatG11B.1.177.570.000281
ORF1ab/nsp2251I251MatAatG11B.1.177.630.002703
ORF1ab/nsp2251I251MatAatG11B.1.2190.009434
ORF1ab/nsp2251I251MatAatG11B.1.2210.000071
ORF1ab/nsp2251I251MatAatG11B.1.2430.00007
ORF1ab/nsp2251I251MatAatG11B.1.30.002618
ORF1ab/nsp2251I251MatAatG11B.1.3110.000275
ORF1ab/nsp2251I251MatAatG11B.1.3510.00003
ORF1ab/nsp2251I251MatAatG11B.1.351.30.000876
ORF1ab/nsp2251I251MatAatG11B.1.36.180.00042
ORF1ab/nsp2251I251MatAatG11B.1.36.280.005747
ORF1ab/nsp2251I251MatAatG11B.1.466.20.000391
ORF1ab/nsp2251I251MatAatG11B.1.4970.000315
ORF1ab/nsp2251I251MatAatG11B.1.5250.000113
ORF1ab/nsp2251I251MatAatG11B.1.5760.000907
ORF1ab/nsp2251I251MatAatG11B.1.6250.002353
ORF1ab/nsp2251I251MatAatG11B.1.6330.041667
ORF1ab/nsp2251I251MatAatG11B.1.6370.000073
ORF1ab/nsp2251I251MatAatG11B.400.000364
ORF1ab/nsp2251I251MatAatG11B.6.60.000889
ORF1ab/nsp2251I251MatAatG11C.30.10.006711
ORF1ab/nsp2251I251MatAatG11P.1.120.000484
ORF1ab/nsp2251I251MatAatG11P.1.130.000898
ORF1ab/nsp2251I251MatAatG11P.1.40.000977
ORF1ab/nsp2251I251MatAatG11Q.10.000126
ORF1ab/nsp2251I251MatAatG11Q.80.000165
ORF1ab/nsp2251I251MatAatG11W.30.005263

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.