CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = I101I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2101I101II281IsynatCatT133213100.9834831106-1108
ORF1ab/nsp2101I101II281IsynatCatA1332220.01651651106-1108

Details of the mutation I101I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2101I101IatCatT13101332All0.000251
ORF1ab/nsp2101I101IatCatA221332All0.000004
ORF1ab/nsp2101I101IatCatT440440B.1.1.70.000394
ORF1ab/nsp2101I101IatCatT108109AY.1030.000671
ORF1ab/nsp2101I101IatCatA1109AY.1030.000006
ORF1ab/nsp2101I101IatCatT7878U.11
ORF1ab/nsp2101I101IatCatT6162AY.40.000095
ORF1ab/nsp2101I101IatCatA162AY.40.000002
ORF1ab/nsp2101I101IatCatT4647B.1.617.20.000173
ORF1ab/nsp2101I101IatCatA147B.1.617.20.000004
ORF1ab/nsp2101I101IatCatT3131AY.60.001275
ORF1ab/nsp2101I101IatCatT3030AY.30.000298
ORF1ab/nsp2101I101IatCatT2828AY.98.10.001356
ORF1ab/nsp2101I101IatCatT2525AY.430.000111
ORF1ab/nsp2101I101IatCatT2525B.1.4970.007869
ORF1ab/nsp2101I101IatCatT2525B.1.5250.002829
ORF1ab/nsp2101I101IatCatT1823B.10.000165
ORF1ab/nsp2101I101IatCatA523B.10.000046
ORF1ab/nsp2101I101IatCatT2222B.1.1770.00029
ORF1ab/nsp2101I101IatCatT2121B.1.4290.000494
ORF1ab/nsp2101I101IatCatT1818AY.4.20.00039
ORF1ab/nsp2101I101IatCatT1717AY.250.000102
ORF1ab/nsp2101I101IatCatT1616AY.1020.000424
ORF1ab/nsp2101I101IatCatT1516B.1.10.000272
ORF1ab/nsp2101I101IatCatA116B.1.10.000018
ORF1ab/nsp2101I101IatCatT1515B.1.3690.004278
ORF1ab/nsp2101I101IatCatT1313B.1.5750.003944
ORF1ab/nsp2101I101IatCatT1112AY.440.000067
ORF1ab/nsp2101I101IatCatA112AY.440.000006
ORF1ab/nsp2101I101IatCatT1212AY.840.005249
ORF1ab/nsp2101I101IatCatT1111B.1.1.10.003594
ORF1ab/nsp2101I101IatCatT1111B.1.20.000097
ORF1ab/nsp2101I101IatCatT99P.10.000142
ORF1ab/nsp2101I101IatCatT58AY.50.000103
ORF1ab/nsp2101I101IatCatA38AY.50.000062
ORF1ab/nsp2101I101IatCatT77AY.1200.00026
ORF1ab/nsp2101I101IatCatT77B.1.1.5190.000278
ORF1ab/nsp2101I101IatCatT77B.1.5960.00061
ORF1ab/nsp2101I101IatCatT66AY.1190.000212
ORF1ab/nsp2101I101IatCatT66B.1.3750.004918
ORF1ab/nsp2101I101IatCatT55AY.330.000334
ORF1ab/nsp2101I101IatCatT55AY.390.000124
ORF1ab/nsp2101I101IatCatT55B.1.177.70.000824
ORF1ab/nsp2101I101IatCatT55B.1.2340.00066
ORF1ab/nsp2101I101IatCatT44AY.290.000063
ORF1ab/nsp2101I101IatCatT44AY.4.50.00043
ORF1ab/nsp2101I101IatCatT44AY.99.20.000369
ORF1ab/nsp2101I101IatCatT34B.1.1600.000094
ORF1ab/nsp2101I101IatCatA14B.1.1600.000031
ORF1ab/nsp2101I101IatCatT44B.1.177.330.006579
ORF1ab/nsp2101I101IatCatA44B.1.258.110.001585
ORF1ab/nsp2101I101IatCatT44P.1.170.000647
ORF1ab/nsp2101I101IatCatT33AY.1210.000406
ORF1ab/nsp2101I101IatCatT33AY.340.000291
ORF1ab/nsp2101I101IatCatT33AY.600.002814
ORF1ab/nsp2101I101IatCatT33AY.750.000168
ORF1ab/nsp2101I101IatCatT33AY.9.20.00011
ORF1ab/nsp2101I101IatCatT33B.1.1.3970.006757
ORF1ab/nsp2101I101IatCatT33B.1.177.210.000229
ORF1ab/nsp2101I101IatCatT33B.1.3510.000089
ORF1ab/nsp2101I101IatCatT33B.1.5260.000071
ORF1ab/nsp2101I101IatCatT33C.370.000348
ORF1ab/nsp2101I101IatCatA220.111111
ORF1ab/nsp2101I101IatCatT22A.2.50.000998
ORF1ab/nsp2101I101IatCatT22AY.1000.000092
ORF1ab/nsp2101I101IatCatT22AY.1050.001286
ORF1ab/nsp2101I101IatCatT22AY.116.10.000623
ORF1ab/nsp2101I101IatCatT22AY.260.000057
ORF1ab/nsp2101I101IatCatT22AY.370.000632
ORF1ab/nsp2101I101IatCatT22AY.470.000062
ORF1ab/nsp2101I101IatCatT22AY.980.000158
ORF1ab/nsp2101I101IatCatT22B.1.1.2840.000215
ORF1ab/nsp2101I101IatCatT22B.1.1.3690.000892
ORF1ab/nsp2101I101IatCatT22B.1.1.3720.001377
ORF1ab/nsp2101I101IatCatT22B.1.1.390.001019
ORF1ab/nsp2101I101IatCatT22B.1.177.440.001038
ORF1ab/nsp2101I101IatCatT22B.1.2580.000133
ORF1ab/nsp2101I101IatCatT22B.1.36.10.002281
ORF1ab/nsp2101I101IatCatT22B.1.438.10.000215
ORF1ab/nsp2101I101IatCatT22B.1.5170.000854
ORF1ab/nsp2101I101IatCatT22B.1.5950.000522
ORF1ab/nsp2101I101IatCatT22D.20.00015
ORF1ab/nsp2101I101IatCatT22P.1.150.000465
ORF1ab/nsp2101I101IatCatT22P.20.000373
ORF1ab/nsp2101I101IatCatT11A.2.5.30.010309
ORF1ab/nsp2101I101IatCatT11AY.1130.000142
ORF1ab/nsp2101I101IatCatT11AY.120.000316
ORF1ab/nsp2101I101IatCatT11AY.160.00038
ORF1ab/nsp2101I101IatCatT11AY.230.00007
ORF1ab/nsp2101I101IatCatT11AY.240.000431
ORF1ab/nsp2101I101IatCatT11AY.360.000148
ORF1ab/nsp2101I101IatCatT11AY.380.000499
ORF1ab/nsp2101I101IatCatT11AY.450.000122
ORF1ab/nsp2101I101IatCatT11AY.46.40.000165
ORF1ab/nsp2101I101IatCatT11AY.550.000917
ORF1ab/nsp2101I101IatCatT11AY.610.000105
ORF1ab/nsp2101I101IatCatT11AY.690.000187
ORF1ab/nsp2101I101IatCatT11AY.700.000209
ORF1ab/nsp2101I101IatCatT11AY.710.000475
ORF1ab/nsp2101I101IatCatT11AY.9.10.000084
ORF1ab/nsp2101I101IatCatT11AY.900.000684
ORF1ab/nsp2101I101IatCatT11AY.940.000443
ORF1ab/nsp2101I101IatCatT11B.1.1.280.000311
ORF1ab/nsp2101I101IatCatT11B.1.1.3050.003861
ORF1ab/nsp2101I101IatCatT11B.1.1.3110.000358
ORF1ab/nsp2101I101IatCatT11B.1.1.3170.000412
ORF1ab/nsp2101I101IatCatT11B.1.1.330.000421
ORF1ab/nsp2101I101IatCatT11B.1.1.3500.04
ORF1ab/nsp2101I101IatCatT11B.1.1.370.000193
ORF1ab/nsp2101I101IatCatT11B.1.1.500.000679
ORF1ab/nsp2101I101IatCatT11B.1.177.770.000726
ORF1ab/nsp2101I101IatCatT11B.1.177.800.001912
ORF1ab/nsp2101I101IatCatT11B.1.177.860.000183
ORF1ab/nsp2101I101IatCatT11B.1.2210.000071
ORF1ab/nsp2101I101IatCatT11B.1.2430.00007
ORF1ab/nsp2101I101IatCatT11B.1.2800.007143
ORF1ab/nsp2101I101IatCatT11B.1.3260.007576
ORF1ab/nsp2101I101IatCatT11B.1.3490.000715
ORF1ab/nsp2101I101IatCatT11B.1.36.170.000494
ORF1ab/nsp2101I101IatCatT11B.1.36.180.00042
ORF1ab/nsp2101I101IatCatT11B.1.36.240.006173
ORF1ab/nsp2101I101IatCatT11B.1.5270.003704
ORF1ab/nsp2101I101IatCatA11B.1.6090.000479
ORF1ab/nsp2101I101IatCatT11B.1.6370.000073
ORF1ab/nsp2101I101IatCatT11B.1.780.008547
ORF1ab/nsp2101I101IatCatT11B.3.10.001658
ORF1ab/nsp2101I101IatCatA11B.6.60.000889
ORF1ab/nsp2101I101IatCatT11C.180.002591
ORF1ab/nsp2101I101IatCatT11C.360.000911
ORF1ab/nsp2101I101IatCatT11C.36.30.000567
ORF1ab/nsp2101I101IatCatT11C.400.027778
ORF1ab/nsp2101I101IatCatT11L.30.003546
ORF1ab/nsp2101I101IatCatT11P.1.10.000318
ORF1ab/nsp2101I101IatCatT11P.1.120.000484
ORF1ab/nsp2101I101IatCatT11P.1.140.000048
ORF1ab/nsp2101I101IatCatT11Q.80.000165
ORF1ab/nsp2101I101IatCatT11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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