CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = H194Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2194H194YH374YnonsynCacTac744174290.9983871385-1387
ORF1ab/nsp2194H194YH374YnonsynCaCTaT7441120.001612691385-1387

Details of the mutation H194Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2194H194YCacTac74297441All0.001421
ORF1ab/nsp2194H194YCaCTaT127441All0.000002
ORF1ab/nsp2194H194YCacTac16641670AY.40.00259
ORF1ab/nsp2194H194YCaCTaT61670AY.40.000009
ORF1ab/nsp2194H194YCacTac13511351B.1.1.70.001209
ORF1ab/nsp2194H194YCacTac11111111B.1.5090.961905
ORF1ab/nsp2194H194YCacTac228228AY.200.008861
ORF1ab/nsp2194H194YCacTac218218B.1.177.510.995434
ORF1ab/nsp2194H194YCacTac196197B.1.617.20.000738
ORF1ab/nsp2194H194YCaCTaT1197B.1.617.20.000004
ORF1ab/nsp2194H194YCacTac195195B.10.001786
ORF1ab/nsp2194H194YCacTac150154B.1.20.001321
ORF1ab/nsp2194H194YCaCTaT4154B.1.20.000035
ORF1ab/nsp2194H194YCacTac105105AY.1030.000652
ORF1ab/nsp2194H194YCacTac9797AY.440.00059
ORF1ab/nsp2194H194YCacTac9292AY.290.001451
ORF1ab/nsp2194H194YCacTac7475P.10.001166
ORF1ab/nsp2194H194YCaCTaT175P.10.000016
ORF1ab/nsp2194H194YCacTac7171W.40.095946
ORF1ab/nsp2194H194YCacTac6363AY.250.000379
ORF1ab/nsp2194H194YCacTac6363B.1.5690.913043
ORF1ab/nsp2194H194YCacTac6161B.1.1770.000803
ORF1ab/nsp2194H194YCacTac5858AY.350.013517
ORF1ab/nsp2194H194YCacTac5858AY.99.20.005345
ORF1ab/nsp2194H194YCacTac5252AY.430.00023
ORF1ab/nsp2194H194YCacTac5252B.1.10.000943
ORF1ab/nsp2194H194YCacTac4747AY.46.20.02986
ORF1ab/nsp2194H194YCacTac4747B.1.4270.002373
ORF1ab/nsp2194H194YCacTac4545A.2.50.022455
ORF1ab/nsp2194H194YCacTac4444AY.340.004266
ORF1ab/nsp2194H194YCacTac4343B.1.5260.001011
ORF1ab/nsp2194H194YCacTac4242B.1.6370.003069
ORF1ab/nsp2194H194YCacTac3939AY.30.000388
ORF1ab/nsp2194H194YCacTac3636Q.10.004548
ORF1ab/nsp2194H194YCacTac3535AY.98.10.001695
ORF1ab/nsp2194H194YCacTac3131AY.4.20.000672
ORF1ab/nsp2194H194YCacTac2929B.1.2340.003826
ORF1ab/nsp2194H194YCacTac2828B.1.1.370.0054
ORF1ab/nsp2194H194YCacTac2727AY.60.00111
ORF1ab/nsp2194H194YCacTac2727AY.820.036635
ORF1ab/nsp2194H194YCacTac2525B.1.177.200.037936
ORF1ab/nsp2194H194YCacTac2323B.1.258.170.002391
ORF1ab/nsp2194H194YCacTac2222AY.690.004107
ORF1ab/nsp2194H194YCacTac2222AY.9.10.001842
ORF1ab/nsp2194H194YCacTac2222B.1.360.00321
ORF1ab/nsp2194H194YCacTac2121B.1.2210.001492
ORF1ab/nsp2194H194YCacTac2020B.1.3510.000595
ORF1ab/nsp2194H194YCacTac1919AY.750.001064
ORF1ab/nsp2194H194YCacTac1919B.1.6210.001682
ORF1ab/nsp2194H194YCacTac1818AY.470.00056
ORF1ab/nsp2194H194YCacTac1818B.1.351.20.005446
ORF1ab/nsp2194H194YCacTac1717B.1.1600.00053
ORF1ab/nsp2194H194YCacTac1616AY.540.001526
ORF1ab/nsp2194H194YCacTac1616B.1.6190.013937
ORF1ab/nsp2194H194YCacTac1515B.1.4290.000353
ORF1ab/nsp2194H194YCacTac1414AY.1020.000371
ORF1ab/nsp2194H194YCacTac1414AY.420.000563
ORF1ab/nsp2194H194YCacTac1414B.1.1.5190.000556
ORF1ab/nsp2194H194YCacTac1414B.1.5960.00122
ORF1ab/nsp2194H194YCacTac1414C.370.001625
ORF1ab/nsp2194H194YCacTac1212B.1.1.700.004093
ORF1ab/nsp2194H194YCacTac1212B.1.177.770.008715
ORF1ab/nsp2194H194YCacTac1111AY.390.000272
ORF1ab/nsp2194H194YCacTac1111AY.980.000869
ORF1ab/nsp2194H194YCacTac1010AY.50.000206
ORF1ab/nsp2194H194YCacTac1010AY.9.20.000367
ORF1ab/nsp2194H194YCacTac1010B.1.1.2220.00204
ORF1ab/nsp2194H194YCacTac1010B.1.5740.021505
ORF1ab/nsp2194H194YCacTac1010C.160.010604
ORF1ab/nsp2194H194YCacTac1010P.1.140.000478
ORF1ab/nsp2194H194YCacTac99AM.21
ORF1ab/nsp2194H194YCacTac99AY.1000.000414
ORF1ab/nsp2194H194YCacTac99B.1.177.70.001484
ORF1ab/nsp2194H194YCacTac99B.1.2430.000626
ORF1ab/nsp2194H194YCacTac88AY.10.003166
ORF1ab/nsp2194H194YCacTac88AY.450.000973
ORF1ab/nsp2194H194YCacTac88B.1.1.1860.027491
ORF1ab/nsp2194H194YCacTac88B.1.1.3560.068376
ORF1ab/nsp2194H194YCacTac88B.1.3110.002197
ORF1ab/nsp2194H194YCacTac88P.20.001493
ORF1ab/nsp2194H194YCacTac77AY.260.000198
ORF1ab/nsp2194H194YCacTac77AY.610.000733
ORF1ab/nsp2194H194YCacTac77AY.850.00299
ORF1ab/nsp2194H194YCacTac66AY.1070.002796
ORF1ab/nsp2194H194YCacTac66AY.1210.000812
ORF1ab/nsp2194H194YCacTac66AY.140.000528
ORF1ab/nsp2194H194YCacTac66AY.23.10.002504
ORF1ab/nsp2194H194YCacTac66B.1.1.250.003411
ORF1ab/nsp2194H194YCacTac66B.1.5520.090909
ORF1ab/nsp2194H194YCacTac66B.1.5800.02439
ORF1ab/nsp2194H194YCacTac66B.1.596.10.056075
ORF1ab/nsp2194H194YCacTac66B.1.5990.021898
ORF1ab/nsp2194H194YCacTac55AY.1190.000177
ORF1ab/nsp2194H194YCacTac55AY.16.10.00235
ORF1ab/nsp2194H194YCacTac55AY.230.000349
ORF1ab/nsp2194H194YCacTac55AY.3.10.000426
ORF1ab/nsp2194H194YCacTac55AY.330.000334
ORF1ab/nsp2194H194YCacTac55AY.460.00052
ORF1ab/nsp2194H194YCacTac55AY.720.006803
ORF1ab/nsp2194H194YCacTac55AY.90.000338
ORF1ab/nsp2194H194YCacTac55B.1.1.2140.000277
ORF1ab/nsp2194H194YCacTac55B.1.1.2940.006329
ORF1ab/nsp2194H194YCacTac55B.1.2580.000333
ORF1ab/nsp2194H194YCacTac55Q.70.005556
ORF1ab/nsp2194H194YCacTac44AY.1130.00057
ORF1ab/nsp2194H194YCacTac44AY.5.30.00135
ORF1ab/nsp2194H194YCacTac44B0.000511
ORF1ab/nsp2194H194YCacTac44B.1.1.2550.012121
ORF1ab/nsp2194H194YCacTac44B.1.1.280.001245
ORF1ab/nsp2194H194YCacTac44B.1.1.4320.005063
ORF1ab/nsp2194H194YCacTac44B.1.5750.001214
ORF1ab/nsp2194H194YCacTac44B.1.617.10.000516
ORF1ab/nsp2194H194YCacTac44B.1.6280.001409
ORF1ab/nsp2194H194YCacTac44M.30.307692
ORF1ab/nsp2194H194YCacTac44Q.80.00066
ORF1ab/nsp2194H194YCacTac33A.10.000846
ORF1ab/nsp2194H194YCacTac33AY.1010.001471
ORF1ab/nsp2194H194YCacTac33AY.46.60.000217
ORF1ab/nsp2194H194YCacTac33AY.480.001395
ORF1ab/nsp2194H194YCacTac33AY.550.002752
ORF1ab/nsp2194H194YCacTac33B.1.1.10.00098
ORF1ab/nsp2194H194YCacTac33B.1.1.2840.000322
ORF1ab/nsp2194H194YCacTac33B.1.177.440.001557
ORF1ab/nsp2194H194YCacTac33B.1.177.570.000843
ORF1ab/nsp2194H194YCacTac33B.1.36.290.001552
ORF1ab/nsp2194H194YCacTac33B.1.3980.008929
ORF1ab/nsp2194H194YCacTac33B.1.4000.001287
ORF1ab/nsp2194H194YCacTac33B.1.438.10.000322
ORF1ab/nsp2194H194YCacTac33B.1.4620.021739
ORF1ab/nsp2194H194YCacTac33B.1.466.20.001174
ORF1ab/nsp2194H194YCacTac33P.1.150.000697
ORF1ab/nsp2194H194YCacTac33P.1.160.001122
ORF1ab/nsp2194H194YCacTac22AY.1160.000574
ORF1ab/nsp2194H194YCacTac22AY.1170.000169
ORF1ab/nsp2194H194YCacTac22AY.1180.000125
ORF1ab/nsp2194H194YCacTac22AY.1200.000074
ORF1ab/nsp2194H194YCacTac22AY.300.000791
ORF1ab/nsp2194H194YCacTac22AY.380.000999
ORF1ab/nsp2194H194YCacTac22AY.590.001059
ORF1ab/nsp2194H194YCacTac22AY.640.00119
ORF1ab/nsp2194H194YCacTac22AY.70.000392
ORF1ab/nsp2194H194YCacTac22AY.7.10.000225
ORF1ab/nsp2194H194YCacTac22AY.700.000417
ORF1ab/nsp2194H194YCacTac22AY.960.004149
ORF1ab/nsp2194H194YCacTac22B.1.1.1110.029412
ORF1ab/nsp2194H194YCacTac22B.1.1.3180.000604
ORF1ab/nsp2194H194YCacTac22B.1.1.330.000842
ORF1ab/nsp2194H194YCacTac22B.1.1.3720.001377
ORF1ab/nsp2194H194YCacTac22B.1.160.260.004843
ORF1ab/nsp2194H194YCacTac22B.1.177.350.001382
ORF1ab/nsp2194H194YCacTac22B.1.1990.008264
ORF1ab/nsp2194H194YCacTac22B.1.36.310.003503
ORF1ab/nsp2194H194YCacTac22B.1.3670.001585
ORF1ab/nsp2194H194YCacTac22B.1.3890.002004
ORF1ab/nsp2194H194YCacTac22B.1.3960.001411
ORF1ab/nsp2194H194YCacTac22B.1.5250.000226
ORF1ab/nsp2194H194YCacTac22B.1.5610.000794
ORF1ab/nsp2194H194YCacTac22B.1.5950.000522
ORF1ab/nsp2194H194YCacTac22B.1.6090.000959
ORF1ab/nsp2194H194YCacTac22B.1.6230.001073
ORF1ab/nsp2194H194YCacTac22B.6.60.001778
ORF1ab/nsp2194H194YCacTac22P.1.10.000635
ORF1ab/nsp2194H194YCacTac22P.1.100.000539
ORF1ab/nsp2194H194YCacTac11A.210.00277
ORF1ab/nsp2194H194YCacTac11A.270.001656
ORF1ab/nsp2194H194YCacTac11AT.10.005128
ORF1ab/nsp2194H194YCacTac11AY.1050.000643
ORF1ab/nsp2194H194YCacTac11AY.1100.000113
ORF1ab/nsp2194H194YCacTac11AY.1140.000231
ORF1ab/nsp2194H194YCacTac11AY.190.00114
ORF1ab/nsp2194H194YCacTac11AY.270.000065
ORF1ab/nsp2194H194YCacTac11AY.29.10.000221
ORF1ab/nsp2194H194YCacTac11AY.320.000532
ORF1ab/nsp2194H194YCacTac11AY.370.000316
ORF1ab/nsp2194H194YCacTac11AY.39.10.00004
ORF1ab/nsp2194H194YCacTac11AY.4.10.000737
ORF1ab/nsp2194H194YCacTac11AY.4.2.10.000149
ORF1ab/nsp2194H194YCacTac11AY.4.50.000107
ORF1ab/nsp2194H194YCacTac11AY.46.40.000165
ORF1ab/nsp2194H194YCacTac11AY.510.000909
ORF1ab/nsp2194H194YCacTac11AY.530.000288
ORF1ab/nsp2194H194YCacTac11AY.580.000907
ORF1ab/nsp2194H194YCacTac11AY.7.20.000559
ORF1ab/nsp2194H194YCacTac11AY.710.000475
ORF1ab/nsp2194H194YCacTac11AY.740.000116
ORF1ab/nsp2194H194YCacTac11AY.80.000606
ORF1ab/nsp2194H194YCacTac11AY.830.001724
ORF1ab/nsp2194H194YCacTac11AY.900.000684
ORF1ab/nsp2194H194YCacTac11AY.910.00073
ORF1ab/nsp2194H194YCacTac11AY.930.000273
ORF1ab/nsp2194H194YCacTac11AY.940.000443
ORF1ab/nsp2194H194YCacTac11AY.950.000761
ORF1ab/nsp2194H194YCacTac11AZ.40.003356
ORF1ab/nsp2194H194YCacTac11B.1.1.1090.04
ORF1ab/nsp2194H194YCacTac11B.1.1.120.007463
ORF1ab/nsp2194H194YCacTac11B.1.1.1570.000913
ORF1ab/nsp2194H194YCacTac11B.1.1.1700.001247
ORF1ab/nsp2194H194YCacTac11B.1.1.2210.010101
ORF1ab/nsp2194H194YCacTac11B.1.1.2250.007194
ORF1ab/nsp2194H194YCacTac11B.1.1.3160.000925
ORF1ab/nsp2194H194YCacTac11B.1.1.3170.000412
ORF1ab/nsp2194H194YCacTac11B.1.1.3260.001761
ORF1ab/nsp2194H194YCacTac11B.1.1.3440.010753
ORF1ab/nsp2194H194YCacTac11B.1.1.3670.055556
ORF1ab/nsp2194H194YCacTac11B.1.1.3680.003086
ORF1ab/nsp2194H194YCacTac11B.1.1.4130.006897
ORF1ab/nsp2194H194YCacTac11B.1.1.4160.000905
ORF1ab/nsp2194H194YCacTac11B.1.1.4340.000349
ORF1ab/nsp2194H194YCacTac11B.1.1.440.00241
ORF1ab/nsp2194H194YCacTac11B.1.1.4420.018519
ORF1ab/nsp2194H194YCacTac11B.1.1.4530.008475
ORF1ab/nsp2194H194YCacTac11B.1.1.4860.001577
ORF1ab/nsp2194H194YCacTac11B.1.1.5210.005348
ORF1ab/nsp2194H194YCacTac11B.1.1.5230.001563
ORF1ab/nsp2194H194YCacTac11B.1.1.80.003584
ORF1ab/nsp2194H194YCacTac11B.1.1080.005814
ORF1ab/nsp2194H194YCacTac11B.1.1110.001175
ORF1ab/nsp2194H194YCacTac11B.1.1280.000635
ORF1ab/nsp2194H194YCacTac11B.1.160.320.004292
ORF1ab/nsp2194H194YCacTac11B.1.1690.014925
ORF1ab/nsp2194H194YCacTac11B.1.177.520.001757
ORF1ab/nsp2194H194YCacTac11B.1.177.530.002392
ORF1ab/nsp2194H194YCacTac11B.1.177.540.000606
ORF1ab/nsp2194H194YCacTac11B.1.177.600.000218
ORF1ab/nsp2194H194YCacTac11B.1.177.730.000566
ORF1ab/nsp2194H194YCacTac11B.1.177.750.001041
ORF1ab/nsp2194H194YCacTac11B.1.177.820.000477
ORF1ab/nsp2194H194YCacTac11B.1.177.830.001481
ORF1ab/nsp2194H194YCacTac11B.1.177.860.000183
ORF1ab/nsp2194H194YCacTac11B.1.2060.000816
ORF1ab/nsp2194H194YCacTac11B.1.214.40.009091
ORF1ab/nsp2194H194YCacTac11B.1.2320.000537
ORF1ab/nsp2194H194YCacTac11B.1.2400.000216
ORF1ab/nsp2194H194YCacTac11B.1.258.110.000396
ORF1ab/nsp2194H194YCacTac11B.1.258.140.00098
ORF1ab/nsp2194H194YCacTac11B.1.258.30.001675
ORF1ab/nsp2194H194YCacTac11B.1.3500.002933
ORF1ab/nsp2194H194YCacTac11B.1.36.10.00114
ORF1ab/nsp2194H194YCacTac11B.1.36.100.004785
ORF1ab/nsp2194H194YCacTac11B.1.36.180.00042
ORF1ab/nsp2194H194YCacTac11B.1.36.360.000602
ORF1ab/nsp2194H194YCacTac11B.1.3950.007042
ORF1ab/nsp2194H194YCacTac11B.1.3970.004854
ORF1ab/nsp2194H194YCacTac11B.1.4020.009804
ORF1ab/nsp2194H194YCacTac11B.1.4090.000781
ORF1ab/nsp2194H194YCacTac11B.1.4160.001269
ORF1ab/nsp2194H194YCacTac11B.1.4220.000812
ORF1ab/nsp2194H194YCacTac11B.1.4700.001404
ORF1ab/nsp2194H194YCacTac11B.1.4710.002732
ORF1ab/nsp2194H194YCacTac11B.1.4990.00105
ORF1ab/nsp2194H194YCacTac11B.1.5030.002488
ORF1ab/nsp2194H194YCacTac11B.1.5170.000427
ORF1ab/nsp2194H194YCacTac11B.1.5400.009709
ORF1ab/nsp2194H194YCacTac11B.1.5820.000491
ORF1ab/nsp2194H194YCacTac11B.1.6250.002353
ORF1ab/nsp2194H194YCacTac11B.1.9.40.006135
ORF1ab/nsp2194H194YCacTac11B.50.038462
ORF1ab/nsp2194H194YCacTac11B.6.10.026316
ORF1ab/nsp2194H194YCacTac11B.6.30.026316
ORF1ab/nsp2194H194YCacTac11C.10.002392
ORF1ab/nsp2194H194YCacTac11D.20.000075
ORF1ab/nsp2194H194YCacTac11N.30.005814
ORF1ab/nsp2194H194YCacTac11N.40.004255
ORF1ab/nsp2194H194YCacTac11P.1.170.000162
ORF1ab/nsp2194H194YCacTac11P.1.20.001156
ORF1ab/nsp2194H194YCacTac11P.1.70.000319
ORF1ab/nsp2194H194YCacTac11P.40.003802
ORF1ab/nsp2194H194YCacTac11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.