CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = G481S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2481G481SG661SnonsynGgtAgt138721387212246-2248

Details of the mutation G481S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2481G481SGgtAgt1387213872All0.002653
ORF1ab/nsp2481G481SGgtAgt1082910829AY.40.016855
ORF1ab/nsp2481G481SGgtAgt963963B.1.617.20.003626
ORF1ab/nsp2481G481SGgtAgt545545B.1.1.70.000488
ORF1ab/nsp2481G481SGgtAgt439439AY.1020.01164
ORF1ab/nsp2481G481SGgtAgt104104P.10.001638
ORF1ab/nsp2481G481SGgtAgt8282AY.5.30.027665
ORF1ab/nsp2481G481SGgtAgt7575AY.1030.000466
ORF1ab/nsp2481G481SGgtAgt6969AY.440.00042
ORF1ab/nsp2481G481SGgtAgt6868AY.430.000301
ORF1ab/nsp2481G481SGgtAgt4949AY.390.001211
ORF1ab/nsp2481G481SGgtAgt3434AY.420.001368
ORF1ab/nsp2481G481SGgtAgt3232AY.250.000192
ORF1ab/nsp2481G481SGgtAgt3131AY.50.00064
ORF1ab/nsp2481G481SGgtAgt3131B.1.20.000273
ORF1ab/nsp2481G481SGgtAgt3030AY.30.000298
ORF1ab/nsp2481G481SGgtAgt2828A.2.50.013972
ORF1ab/nsp2481G481SGgtAgt2626B.1.351.30.022787
ORF1ab/nsp2481G481SGgtAgt2323B.1.10.000417
ORF1ab/nsp2481G481SGgtAgt1515AY.98.10.000726
ORF1ab/nsp2481G481SGgtAgt1515B.4.21
ORF1ab/nsp2481G481SGgtAgt1515P.1.10.004765
ORF1ab/nsp2481G481SGgtAgt1515P.1.140.000717
ORF1ab/nsp2481G481SGgtAgt1313AY.460.001353
ORF1ab/nsp2481G481SGgtAgt1313B.10.000119
ORF1ab/nsp2481G481SGgtAgt1212AY.100.006359
ORF1ab/nsp2481G481SGgtAgt1212AY.450.00146
ORF1ab/nsp2481G481SGgtAgt1111AY.230.000767
ORF1ab/nsp2481G481SGgtAgt1010B.40.022075
ORF1ab/nsp2481G481SGgtAgt99AY.1200.000335
ORF1ab/nsp2481G481SGgtAgt99B.1.2210.000639
ORF1ab/nsp2481G481SGgtAgt99B.1.438.10.000965
ORF1ab/nsp2481G481SGgtAgt88AY.1000.000368
ORF1ab/nsp2481G481SGgtAgt88AY.260.000226
ORF1ab/nsp2481G481SGgtAgt77AY.1190.000247
ORF1ab/nsp2481G481SGgtAgt77AY.75.10.001262
ORF1ab/nsp2481G481SGgtAgt77P.1.150.001626
ORF1ab/nsp2481G481SGgtAgt66AY.1170.000507
ORF1ab/nsp2481G481SGgtAgt66AY.340.000582
ORF1ab/nsp2481G481SGgtAgt66AY.360.000889
ORF1ab/nsp2481G481SGgtAgt66B.1.1.2220.001224
ORF1ab/nsp2481G481SGgtAgt66B.1.2340.000792
ORF1ab/nsp2481G481SGgtAgt66B.1.5090.005195
ORF1ab/nsp2481G481SGgtAgt55AY.1060.001674
ORF1ab/nsp2481G481SGgtAgt55AY.1130.000712
ORF1ab/nsp2481G481SGgtAgt55AY.4.50.000537
ORF1ab/nsp2481G481SGgtAgt55AY.980.000395
ORF1ab/nsp2481G481SGgtAgt55B.1.1.3060.002192
ORF1ab/nsp2481G481SGgtAgt55B.1.1.3620.02809
ORF1ab/nsp2481G481SGgtAgt55B.1.1770.000066
ORF1ab/nsp2481G481SGgtAgt55B.1.3510.000149
ORF1ab/nsp2481G481SGgtAgt55B.1.5260.000118
ORF1ab/nsp2481G481SGgtAgt55P.1.170.000809
ORF1ab/nsp2481G481SGgtAgt44AY.1160.001147
ORF1ab/nsp2481G481SGgtAgt44AY.116.10.001246
ORF1ab/nsp2481G481SGgtAgt44AY.330.000267
ORF1ab/nsp2481G481SGgtAgt44AY.46.20.002541
ORF1ab/nsp2481G481SGgtAgt33AY.160.001139
ORF1ab/nsp2481G481SGgtAgt33AY.34.10.00153
ORF1ab/nsp2481G481SGgtAgt33AY.410.000882
ORF1ab/nsp2481G481SGgtAgt33AY.470.000093
ORF1ab/nsp2481G481SGgtAgt33AY.9.20.00011
ORF1ab/nsp2481G481SGgtAgt33B.1.1.2140.000166
ORF1ab/nsp2481G481SGgtAgt33B.1.2580.0002
ORF1ab/nsp2481G481SGgtAgt33B.1.351.20.000908
ORF1ab/nsp2481G481SGgtAgt22AY.1080.002205
ORF1ab/nsp2481G481SGgtAgt22AY.1180.000125
ORF1ab/nsp2481G481SGgtAgt22AY.140.000176
ORF1ab/nsp2481G481SGgtAgt22AY.190.002281
ORF1ab/nsp2481G481SGgtAgt22AY.350.000466
ORF1ab/nsp2481G481SGgtAgt22AY.4.20.000043
ORF1ab/nsp2481G481SGgtAgt22AY.4.30.001684
ORF1ab/nsp2481G481SGgtAgt22AY.400.001929
ORF1ab/nsp2481G481SGgtAgt22AY.46.60.000144
ORF1ab/nsp2481G481SGgtAgt22AY.5.40.000553
ORF1ab/nsp2481G481SGgtAgt22AY.590.001059
ORF1ab/nsp2481G481SGgtAgt22AY.740.000231
ORF1ab/nsp2481G481SGgtAgt22B.1.1.3480.001592
ORF1ab/nsp2481G481SGgtAgt22B.1.360.000292
ORF1ab/nsp2481G481SGgtAgt22B.1.5950.000522
ORF1ab/nsp2481G481SGgtAgt22B.1.6230.001073
ORF1ab/nsp2481G481SGgtAgt22Q.10.000253
ORF1ab/nsp2481G481SGgtAgt11A.23.10.000704
ORF1ab/nsp2481G481SGgtAgt11AY.1010.00049
ORF1ab/nsp2481G481SGgtAgt11AY.1070.000466
ORF1ab/nsp2481G481SGgtAgt11AY.1100.000113
ORF1ab/nsp2481G481SGgtAgt11AY.1210.000135
ORF1ab/nsp2481G481SGgtAgt11AY.16.10.00047
ORF1ab/nsp2481G481SGgtAgt11AY.270.000065
ORF1ab/nsp2481G481SGgtAgt11AY.290.000016
ORF1ab/nsp2481G481SGgtAgt11AY.320.000532
ORF1ab/nsp2481G481SGgtAgt11AY.39.10.00004
ORF1ab/nsp2481G481SGgtAgt11AY.39.1.10.000725
ORF1ab/nsp2481G481SGgtAgt11AY.4.2.10.000149
ORF1ab/nsp2481G481SGgtAgt11AY.4.40.000409
ORF1ab/nsp2481G481SGgtAgt11AY.46.40.000165
ORF1ab/nsp2481G481SGgtAgt11AY.480.000465
ORF1ab/nsp2481G481SGgtAgt11AY.510.000909
ORF1ab/nsp2481G481SGgtAgt11AY.570.000656
ORF1ab/nsp2481G481SGgtAgt11AY.580.000907
ORF1ab/nsp2481G481SGgtAgt11AY.610.000105
ORF1ab/nsp2481G481SGgtAgt11AY.670.000464
ORF1ab/nsp2481G481SGgtAgt11AY.70.000196
ORF1ab/nsp2481G481SGgtAgt11AY.710.000475
ORF1ab/nsp2481G481SGgtAgt11AY.720.001361
ORF1ab/nsp2481G481SGgtAgt11AY.730.000665
ORF1ab/nsp2481G481SGgtAgt11AY.770.001127
ORF1ab/nsp2481G481SGgtAgt11AY.840.000437
ORF1ab/nsp2481G481SGgtAgt11AY.910.00073
ORF1ab/nsp2481G481SGgtAgt11AY.930.000273
ORF1ab/nsp2481G481SGgtAgt11AY.990.001049
ORF1ab/nsp2481G481SGgtAgt11B.1.1.1210.002427
ORF1ab/nsp2481G481SGgtAgt11B.1.1.3080.011765
ORF1ab/nsp2481G481SGgtAgt11B.1.1.3160.000925
ORF1ab/nsp2481G481SGgtAgt11B.1.1.3170.000412
ORF1ab/nsp2481G481SGgtAgt11B.1.1.5170.006803
ORF1ab/nsp2481G481SGgtAgt11B.1.1420.002899
ORF1ab/nsp2481G481SGgtAgt11B.1.177.110.001698
ORF1ab/nsp2481G481SGgtAgt11B.1.177.120.000152
ORF1ab/nsp2481G481SGgtAgt11B.1.177.450.000381
ORF1ab/nsp2481G481SGgtAgt11B.1.177.510.004566
ORF1ab/nsp2481G481SGgtAgt11B.1.177.790.002342
ORF1ab/nsp2481G481SGgtAgt11B.1.177.810.000189
ORF1ab/nsp2481G481SGgtAgt11B.1.2430.00007
ORF1ab/nsp2481G481SGgtAgt11B.1.258.170.000104
ORF1ab/nsp2481G481SGgtAgt11B.1.30.002618
ORF1ab/nsp2481G481SGgtAgt11B.1.36.390.002217
ORF1ab/nsp2481G481SGgtAgt11B.1.3690.000285
ORF1ab/nsp2481G481SGgtAgt11B.1.3830.009009
ORF1ab/nsp2481G481SGgtAgt11B.1.4080.00369
ORF1ab/nsp2481G481SGgtAgt11B.1.4220.000812
ORF1ab/nsp2481G481SGgtAgt11B.1.4240.008065
ORF1ab/nsp2481G481SGgtAgt11B.1.4270.00005
ORF1ab/nsp2481G481SGgtAgt11B.1.4330.003195
ORF1ab/nsp2481G481SGgtAgt11B.1.4620.007246
ORF1ab/nsp2481G481SGgtAgt11B.1.5760.000907
ORF1ab/nsp2481G481SGgtAgt11B.1.617.10.000129
ORF1ab/nsp2481G481SGgtAgt11B.1.6210.000089
ORF1ab/nsp2481G481SGgtAgt11B.1.6280.000352
ORF1ab/nsp2481G481SGgtAgt11B.400.000364
ORF1ab/nsp2481G481SGgtAgt11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.