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CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = G313C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2313G313CG493CnonsynGgtTgt25225211742-1744

Details of the mutation G313C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2313G313CGgtTgt252252All0.000048
ORF1ab/nsp2313G313CGgtTgt3737P.10.000583
ORF1ab/nsp2313G313CGgtTgt3131B.1.1.70.000028
ORF1ab/nsp2313G313CGgtTgt2323AY.420.000925
ORF1ab/nsp2313G313CGgtTgt1515AY.430.000066
ORF1ab/nsp2313G313CGgtTgt1212AY.750.000672
ORF1ab/nsp2313G313CGgtTgt1212AY.9.20.000441
ORF1ab/nsp2313G313CGgtTgt1111B.1.5260.000259
ORF1ab/nsp2313G313CGgtTgt88AY.40.000012
ORF1ab/nsp2313G313CGgtTgt88AY.440.000049
ORF1ab/nsp2313G313CGgtTgt88B.1.177.600.001747
ORF1ab/nsp2313G313CGgtTgt88B.1.20.00007
ORF1ab/nsp2313G313CGgtTgt66AY.250.000036
ORF1ab/nsp2313G313CGgtTgt66B.1.360.000875
ORF1ab/nsp2313G313CGgtTgt66B.1.617.20.000023
ORF1ab/nsp2313G313CGgtTgt55B.10.000046
ORF1ab/nsp2313G313CGgtTgt55B.1.6370.000365
ORF1ab/nsp2313G313CGgtTgt44AY.330.000267
ORF1ab/nsp2313G313CGgtTgt44D.20.0003
ORF1ab/nsp2313G313CGgtTgt33AY.30.00003
ORF1ab/nsp2313G313CGgtTgt33B.1.1770.00004
ORF1ab/nsp2313G313CGgtTgt220.111111
ORF1ab/nsp2313G313CGgtTgt22AY.1030.000012
ORF1ab/nsp2313G313CGgtTgt22AY.1190.000071
ORF1ab/nsp2313G313CGgtTgt22AY.260.000057
ORF1ab/nsp2313G313CGgtTgt22AY.270.000129
ORF1ab/nsp2313G313CGgtTgt22AY.98.10.000097
ORF1ab/nsp2313G313CGgtTgt22B.1.10.000036
ORF1ab/nsp2313G313CGgtTgt22B.1.2060.001631
ORF1ab/nsp2313G313CGgtTgt11AY.23.10.000417
ORF1ab/nsp2313G313CGgtTgt11AY.340.000097
ORF1ab/nsp2313G313CGgtTgt11AY.39.10.00004
ORF1ab/nsp2313G313CGgtTgt11AY.60.000041
ORF1ab/nsp2313G313CGgtTgt11AY.9.10.000084
ORF1ab/nsp2313G313CGgtTgt11AY.980.000079
ORF1ab/nsp2313G313CGgtTgt11AY.99.20.000092
ORF1ab/nsp2313G313CGgtTgt11B.1.1.1940.00495
ORF1ab/nsp2313G313CGgtTgt11B.1.1.330.000421
ORF1ab/nsp2313G313CGgtTgt11B.1.1.3690.000446
ORF1ab/nsp2313G313CGgtTgt11B.1.1.4320.001266
ORF1ab/nsp2313G313CGgtTgt11B.1.177.210.000076
ORF1ab/nsp2313G313CGgtTgt11B.1.2210.000071
ORF1ab/nsp2313G313CGgtTgt11B.1.3690.000285
ORF1ab/nsp2313G313CGgtTgt11B.1.3890.001002
ORF1ab/nsp2313G313CGgtTgt11B.1.4290.000024
ORF1ab/nsp2313G313CGgtTgt11B.1.5760.000907
ORF1ab/nsp2313G313CGgtTgt11B.1.5800.004065
ORF1ab/nsp2313G313CGgtTgt11B.1.9.50.005682
ORF1ab/nsp2313G313CGgtTgt11B.60.00091
ORF1ab/nsp2313G313CGgtTgt11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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