CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = G262S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2262G262SG442SnonsynGgtAgt160015990.9993751589-1591
ORF1ab/nsp2262G262SG442SnonsynGgTAgC160010.0006251589-1591

Details of the mutation G262S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2262G262SGgtAgt15991600All0.000306
ORF1ab/nsp2262G262SGgTAgC11600All0
ORF1ab/nsp2262G262SGgtAgt221221AY.40.000344
ORF1ab/nsp2262G262SGgtAgt180180B.1.1.70.000161
ORF1ab/nsp2262G262SGgtAgt170170B.1.10.003084
ORF1ab/nsp2262G262SGgtAgt145145AY.250.000872
ORF1ab/nsp2262G262SGgtAgt144144B.1.2520.953642
ORF1ab/nsp2262G262SGgtAgt6768B.1.617.20.000252
ORF1ab/nsp2262G262SGgTAgC168B.1.617.20.000004
ORF1ab/nsp2262G262SGgtAgt3838AY.740.004395
ORF1ab/nsp2262G262SGgtAgt3838B.10.000348
ORF1ab/nsp2262G262SGgtAgt3434B.1.1.4490.772727
ORF1ab/nsp2262G262SGgtAgt3131AY.46.40.0051
ORF1ab/nsp2262G262SGgtAgt2828AY.1190.000989
ORF1ab/nsp2262G262SGgtAgt2424AY.30.000239
ORF1ab/nsp2262G262SGgtAgt2424B.1.258.170.002495
ORF1ab/nsp2262G262SGgtAgt2121B.1.1770.000277
ORF1ab/nsp2262G262SGgtAgt2020B.1.1.4340.006971
ORF1ab/nsp2262G262SGgtAgt1919AY.430.000084
ORF1ab/nsp2262G262SGgtAgt1818B.1.1.2140.000998
ORF1ab/nsp2262G262SGgtAgt1818B.1.3510.000535
ORF1ab/nsp2262G262SGgtAgt1717AY.9.20.000624
ORF1ab/nsp2262G262SGgtAgt1717B.1.2340.002243
ORF1ab/nsp2262G262SGgtAgt1616AY.230.001116
ORF1ab/nsp2262G262SGgtAgt1616B.1.1.3480.012739
ORF1ab/nsp2262G262SGgtAgt1313AY.1030.000081
ORF1ab/nsp2262G262SGgtAgt1313AY.120.10.004173
ORF1ab/nsp2262G262SGgtAgt1212AY.440.000073
ORF1ab/nsp2262G262SGgtAgt1111B.1.5260.000259
ORF1ab/nsp2262G262SGgtAgt1010AY.91.10.04065
ORF1ab/nsp2262G262SGgtAgt1010B.1.5610.00397
ORF1ab/nsp2262G262SGgtAgt99B.1.1.370.001736
ORF1ab/nsp2262G262SGgtAgt99B.1.20.000079
ORF1ab/nsp2262G262SGgtAgt99B.1.6190.00784
ORF1ab/nsp2262G262SGgtAgt99P.1.40.008789
ORF1ab/nsp2262G262SGgtAgt88B.1.1600.00025
ORF1ab/nsp2262G262SGgtAgt88P.20.001493
ORF1ab/nsp2262G262SGgtAgt77B.1.2430.000487
ORF1ab/nsp2262G262SGgtAgt66AY.390.000148
ORF1ab/nsp2262G262SGgtAgt66AY.750.000336
ORF1ab/nsp2262G262SGgtAgt66B.1.6210.000531
ORF1ab/nsp2262G262SGgtAgt55AY.1170.000423
ORF1ab/nsp2262G262SGgtAgt55AY.200.000194
ORF1ab/nsp2262G262SGgtAgt55AY.300.001979
ORF1ab/nsp2262G262SGgtAgt55B.1.4290.000118
ORF1ab/nsp2262G262SGgtAgt55B.150.087719
ORF1ab/nsp2262G262SGgtAgt440.222222
ORF1ab/nsp2262G262SGgtAgt44AY.260.000113
ORF1ab/nsp2262G262SGgtAgt44AY.290.000063
ORF1ab/nsp2262G262SGgtAgt44AY.460.000416
ORF1ab/nsp2262G262SGgtAgt44AY.90.00027
ORF1ab/nsp2262G262SGgtAgt44P.10.000063
ORF1ab/nsp2262G262SGgtAgt33AY.1020.00008
ORF1ab/nsp2262G262SGgtAgt33AY.1200.000112
ORF1ab/nsp2262G262SGgtAgt33AY.160.001139
ORF1ab/nsp2262G262SGgtAgt33AY.330.0002
ORF1ab/nsp2262G262SGgtAgt33AY.60.000123
ORF1ab/nsp2262G262SGgtAgt33B.1.1.330.001263
ORF1ab/nsp2262G262SGgtAgt33B.1.2210.000213
ORF1ab/nsp2262G262SGgtAgt33Q.30.000435
ORF1ab/nsp2262G262SGgtAgt22AD.20.000438
ORF1ab/nsp2262G262SGgtAgt22AY.1040.003968
ORF1ab/nsp2262G262SGgtAgt22AY.320.001065
ORF1ab/nsp2262G262SGgtAgt22AY.420.00008
ORF1ab/nsp2262G262SGgtAgt22AY.50.000041
ORF1ab/nsp2262G262SGgtAgt22AY.610.00021
ORF1ab/nsp2262G262SGgtAgt22B.1.1.2200.003717
ORF1ab/nsp2262G262SGgtAgt22B.1.1.250.001137
ORF1ab/nsp2262G262SGgtAgt22B.1.1.2750.022472
ORF1ab/nsp2262G262SGgtAgt22B.1.1.5140.076923
ORF1ab/nsp2262G262SGgtAgt22B.1.1.530.027397
ORF1ab/nsp2262G262SGgtAgt22B.1.36.180.00084
ORF1ab/nsp2262G262SGgtAgt22B.1.617.10.000258
ORF1ab/nsp2262G262SGgtAgt22P.1.140.000096
ORF1ab/nsp2262G262SGgtAgt22R.10.00018
ORF1ab/nsp2262G262SGgtAgt11AE.80.000489
ORF1ab/nsp2262G262SGgtAgt11AY.1050.000643
ORF1ab/nsp2262G262SGgtAgt11AY.1060.000335
ORF1ab/nsp2262G262SGgtAgt11AY.120.000316
ORF1ab/nsp2262G262SGgtAgt11AY.240.000431
ORF1ab/nsp2262G262SGgtAgt11AY.340.000097
ORF1ab/nsp2262G262SGgtAgt11AY.350.000233
ORF1ab/nsp2262G262SGgtAgt11AY.360.000148
ORF1ab/nsp2262G262SGgtAgt11AY.470.000031
ORF1ab/nsp2262G262SGgtAgt11AY.540.000095
ORF1ab/nsp2262G262SGgtAgt11AY.7.20.000559
ORF1ab/nsp2262G262SGgtAgt11AY.980.000079
ORF1ab/nsp2262G262SGgtAgt11AY.98.10.000048
ORF1ab/nsp2262G262SGgtAgt11B.1.1.10.000327
ORF1ab/nsp2262G262SGgtAgt11B.1.1.1340.011364
ORF1ab/nsp2262G262SGgtAgt11B.1.1.2770.000759
ORF1ab/nsp2262G262SGgtAgt11B.1.1.3060.000438
ORF1ab/nsp2262G262SGgtAgt11B.1.1.3330.001076
ORF1ab/nsp2262G262SGgtAgt11B.1.1.3510.002793
ORF1ab/nsp2262G262SGgtAgt11B.1.1.3710.010417
ORF1ab/nsp2262G262SGgtAgt11B.1.1.3880.045455
ORF1ab/nsp2262G262SGgtAgt11B.1.1.4090.002833
ORF1ab/nsp2262G262SGgtAgt11B.1.1.4190.007407
ORF1ab/nsp2262G262SGgtAgt11B.1.1.440.00241
ORF1ab/nsp2262G262SGgtAgt11B.1.1.500.000679
ORF1ab/nsp2262G262SGgtAgt11B.1.1.5190.00004
ORF1ab/nsp2262G262SGgtAgt11B.1.160.310.008065
ORF1ab/nsp2262G262SGgtAgt11B.1.177.520.001757
ORF1ab/nsp2262G262SGgtAgt11B.1.177.770.000726
ORF1ab/nsp2262G262SGgtAgt11B.1.2320.000537
ORF1ab/nsp2262G262SGgtAgt11B.1.258.90.005
ORF1ab/nsp2262G262SGgtAgt11B.1.351.50.0006
ORF1ab/nsp2262G262SGgtAgt11B.1.360.000146
ORF1ab/nsp2262G262SGgtAgt11B.1.4270.00005
ORF1ab/nsp2262G262SGgtAgt11B.1.5170.000427
ORF1ab/nsp2262G262SGgtAgt11B.1.5870.001898
ORF1ab/nsp2262G262SGgtAgt11B.1.5950.000261
ORF1ab/nsp2262G262SGgtAgt11B.1.6370.000073
ORF1ab/nsp2262G262SGgtAgt11B.400.000364
ORF1ab/nsp2262G262SGgtAgt11C.370.000116
ORF1ab/nsp2262G262SGgtAgt11N.90.005952
ORF1ab/nsp2262G262SGgtAgt11P.1.70.000319
ORF1ab/nsp2262G262SGgtAgt11P.30.001595
ORF1ab/nsp2262G262SGgtAgt11P.70.004367

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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