CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = E442G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2442E442GE622GnonsyngAagGa3273260.9969422129-2131
ORF1ab/nsp2442E442GE622GnonsyngAAgGC32710.00305812129-2131

Details of the mutation E442G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2442E442GgAagGa326327All0.000062
ORF1ab/nsp2442E442GgAAgGC1327All0
ORF1ab/nsp2442E442GgAagGa131131B.1.1.70.000117
ORF1ab/nsp2442E442GgAagGa7676B.1.20.000669
ORF1ab/nsp2442E442GgAagGa3131AY.1030.000192
ORF1ab/nsp2442E442GgAagGa2828AY.40.000044
ORF1ab/nsp2442E442GgAagGa88B.1.10.000145
ORF1ab/nsp2442E442GgAagGa77B.10.000064
ORF1ab/nsp2442E442GgAagGa66B.1.617.20.000023
ORF1ab/nsp2442E442GgAagGa33AY.580.002722
ORF1ab/nsp2442E442GgAagGa33AY.7.20.001678
ORF1ab/nsp2442E442GgAagGa22AY.1210.000271
ORF1ab/nsp2442E442GgAagGa12AY.440.000006
ORF1ab/nsp2442E442GgAAgGC12AY.440.000006
ORF1ab/nsp2442E442GgAagGa22AY.980.000158
ORF1ab/nsp2442E442GgAagGa22B.1.1.280.000622
ORF1ab/nsp2442E442GgAagGa22B.1.2430.000139
ORF1ab/nsp2442E442GgAagGa110.055556
ORF1ab/nsp2442E442GgAagGa11AY.1000.000046
ORF1ab/nsp2442E442GgAagGa11AY.1020.000027
ORF1ab/nsp2442E442GgAagGa11AY.20.000356
ORF1ab/nsp2442E442GgAagGa11AY.260.000028
ORF1ab/nsp2442E442GgAagGa11AY.300.000396
ORF1ab/nsp2442E442GgAagGa11AY.430.000004
ORF1ab/nsp2442E442GgAagGa11AY.46.20.000635
ORF1ab/nsp2442E442GgAagGa11AY.46.60.000072
ORF1ab/nsp2442E442GgAagGa11AY.9.10.000084
ORF1ab/nsp2442E442GgAagGa11AY.98.10.000048
ORF1ab/nsp2442E442GgAagGa11B.1.1.3720.000689
ORF1ab/nsp2442E442GgAagGa11B.1.1.5190.00004
ORF1ab/nsp2442E442GgAagGa11B.1.1770.000013
ORF1ab/nsp2442E442GgAagGa11B.1.2580.000067
ORF1ab/nsp2442E442GgAagGa11B.1.258.170.000104
ORF1ab/nsp2442E442GgAagGa11B.1.3510.00003
ORF1ab/nsp2442E442GgAagGa11B.1.36.190.009259
ORF1ab/nsp2442E442GgAagGa11B.1.3890.001002
ORF1ab/nsp2442E442GgAagGa11B.1.3960.000706
ORF1ab/nsp2442E442GgAagGa11B.1.5750.000303
ORF1ab/nsp2442E442GgAagGa11B.1.5950.000261
ORF1ab/nsp2442E442GgAagGa11B.1.5960.000087
ORF1ab/nsp2442E442GgAagGa11B.1.6090.000479

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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