CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = E442A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2442E442AE622AnonsyngAagCa46946912129-2131

Details of the mutation E442A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2442E442AgAagCa469469All0.00009
ORF1ab/nsp2442E442AgAagCa281281AY.370.088812
ORF1ab/nsp2442E442AgAagCa158158B.1.1.70.000141
ORF1ab/nsp2442E442AgAagCa1212AY.250.000072
ORF1ab/nsp2442E442AgAagCa66B.1.617.20.000023
ORF1ab/nsp2442E442AgAagCa22AY.120.10.000642
ORF1ab/nsp2442E442AgAagCa22P.10.000032
ORF1ab/nsp2442E442AgAagCa22P.1.150.000465
ORF1ab/nsp2442E442AgAagCa11AY.130.000161
ORF1ab/nsp2442E442AgAagCa11AY.30.00001
ORF1ab/nsp2442E442AgAagCa11AY.600.000938
ORF1ab/nsp2442E442AgAagCa11AY.610.000105
ORF1ab/nsp2442E442AgAagCa11B.1.177.650.000665
ORF1ab/nsp2442E442AgAagCa11B.1.5750.000303

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.