CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = E201D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2201E201DE381DnonsyngaGgaT124712370.9919811406-1408
ORF1ab/nsp2201E201DE381DnonsyngaGgaC1247100.008019251406-1408

Details of the mutation E201D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2201E201DgaGgaT12371247All0.000237
ORF1ab/nsp2201E201DgaGgaC101247All0.000002
ORF1ab/nsp2201E201DgaGgaT581581B.1.160.170.988095
ORF1ab/nsp2201E201DgaGgaT117118B.1.1.70.000105
ORF1ab/nsp2201E201DgaGgaC1118B.1.1.70.000001
ORF1ab/nsp2201E201DgaGgaT9696AY.430.000425
ORF1ab/nsp2201E201DgaGgaT6565B.1.617.20.000245
ORF1ab/nsp2201E201DgaGgaT6263AY.40.000096
ORF1ab/nsp2201E201DgaGgaC163AY.40.000002
ORF1ab/nsp2201E201DgaGgaT4444AY.250.000265
ORF1ab/nsp2201E201DgaGgaT1919AY.30.000189
ORF1ab/nsp2201E201DgaGgaT1818B.1.5960.001568
ORF1ab/nsp2201E201DgaGgaT1717AY.1030.000106
ORF1ab/nsp2201E201DgaGgaT1117AY.440.000067
ORF1ab/nsp2201E201DgaGgaC617AY.440.000037
ORF1ab/nsp2201E201DgaGgaT1414AY.4.20.000304
ORF1ab/nsp2201E201DgaGgaT1414P.10.000221
ORF1ab/nsp2201E201DgaGgaT1111AY.460.001145
ORF1ab/nsp2201E201DgaGgaT1010B.1.1600.000312
ORF1ab/nsp2201E201DgaGgaT99AY.1190.000318
ORF1ab/nsp2201E201DgaGgaT99AY.390.000222
ORF1ab/nsp2201E201DgaGgaT88AY.320.00426
ORF1ab/nsp2201E201DgaGgaT88AY.50.000165
ORF1ab/nsp2201E201DgaGgaT77AY.1020.000186
ORF1ab/nsp2201E201DgaGgaT77AY.98.10.000339
ORF1ab/nsp2201E201DgaGgaT66A.280.015873
ORF1ab/nsp2201E201DgaGgaT66B.1.5580.027397
ORF1ab/nsp2201E201DgaGgaT55B.10.000046
ORF1ab/nsp2201E201DgaGgaT44AY.230.000279
ORF1ab/nsp2201E201DgaGgaT44B.1.1280.002541
ORF1ab/nsp2201E201DgaGgaT44B.1.5070.044944
ORF1ab/nsp2201E201DgaGgaT44P.1.170.000647
ORF1ab/nsp2201E201DgaGgaT33AY.200.000117
ORF1ab/nsp2201E201DgaGgaT33AY.270.000194
ORF1ab/nsp2201E201DgaGgaT33AY.4.50.000322
ORF1ab/nsp2201E201DgaGgaT33AY.750.000168
ORF1ab/nsp2201E201DgaGgaT33B.1.1.5190.000119
ORF1ab/nsp2201E201DgaGgaT33B.1.20.000026
ORF1ab/nsp2201E201DgaGgaT33B.1.5260.000071
ORF1ab/nsp2201E201DgaGgaT22AY.260.000057
ORF1ab/nsp2201E201DgaGgaT22AY.290.000032
ORF1ab/nsp2201E201DgaGgaT22AY.3.10.000171
ORF1ab/nsp2201E201DgaGgaT22AY.330.000134
ORF1ab/nsp2201E201DgaGgaT22AY.610.00021
ORF1ab/nsp2201E201DgaGgaT22AY.730.001331
ORF1ab/nsp2201E201DgaGgaT22B.1.10.000036
ORF1ab/nsp2201E201DgaGgaT22B.1.1.3540.008772
ORF1ab/nsp2201E201DgaGgaT12B.1.3510.00003
ORF1ab/nsp2201E201DgaGgaC12B.1.3510.00003
ORF1ab/nsp2201E201DgaGgaT22B.1.36.190.018519
ORF1ab/nsp2201E201DgaGgaT22B.1.617.10.000258
ORF1ab/nsp2201E201DgaGgaT22P.1.150.000465
ORF1ab/nsp2201E201DgaGgaT11AY.1000.000046
ORF1ab/nsp2201E201DgaGgaT11AY.1200.000037
ORF1ab/nsp2201E201DgaGgaT11AY.130.000161
ORF1ab/nsp2201E201DgaGgaT11AY.34.10.00051
ORF1ab/nsp2201E201DgaGgaT11AY.360.000148
ORF1ab/nsp2201E201DgaGgaT11AY.46.60.000072
ORF1ab/nsp2201E201DgaGgaT11AY.470.000031
ORF1ab/nsp2201E201DgaGgaT11AY.580.000907
ORF1ab/nsp2201E201DgaGgaT11AY.680.000274
ORF1ab/nsp2201E201DgaGgaT11AY.70.000196
ORF1ab/nsp2201E201DgaGgaT11AY.840.000437
ORF1ab/nsp2201E201DgaGgaT11AY.90.000068
ORF1ab/nsp2201E201DgaGgaT11AY.910.00073
ORF1ab/nsp2201E201DgaGgaT11AY.980.000079
ORF1ab/nsp2201E201DgaGgaT11B.1.1.280.000311
ORF1ab/nsp2201E201DgaGgaT11B.1.1.3050.003861
ORF1ab/nsp2201E201DgaGgaT11B.1.1.390.00051
ORF1ab/nsp2201E201DgaGgaT11B.1.160.150.00495
ORF1ab/nsp2201E201DgaGgaT11B.1.1770.000013
ORF1ab/nsp2201E201DgaGgaT11B.1.177.100.000878
ORF1ab/nsp2201E201DgaGgaT11B.1.177.120.000152
ORF1ab/nsp2201E201DgaGgaT11B.1.177.200.001517
ORF1ab/nsp2201E201DgaGgaT11B.1.177.540.000606
ORF1ab/nsp2201E201DgaGgaT11B.1.214.20.0006
ORF1ab/nsp2201E201DgaGgaT11B.1.2210.000071
ORF1ab/nsp2201E201DgaGgaC11B.1.2430.00007
ORF1ab/nsp2201E201DgaGgaT11B.1.351.30.000876
ORF1ab/nsp2201E201DgaGgaT11B.1.3620.001541
ORF1ab/nsp2201E201DgaGgaT11B.1.3990.001934
ORF1ab/nsp2201E201DgaGgaT11C.350.000774
ORF1ab/nsp2201E201DgaGgaT11C.370.000116
ORF1ab/nsp2201E201DgaGgaT11D.20.000075
ORF1ab/nsp2201E201DgaGgaT11P.20.000187
ORF1ab/nsp2201E201DgaGgaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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