CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = A596V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2596A596VA776VnonsyngCtgTt120712050.9983432591-2593
ORF1ab/nsp2596A596VA776VnonsyngCTgTC120720.0016572591-2593

Details of the mutation A596V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2596A596VgCtgTt12051207All0.00023
ORF1ab/nsp2596A596VgCTgTC21207All0
ORF1ab/nsp2596A596VgCtgTt781781AU.10.988608
ORF1ab/nsp2596A596VgCtgTt7878B.1.1.70.00007
ORF1ab/nsp2596A596VgCtgTt7373AY.40.000114
ORF1ab/nsp2596A596VgCtgTt2020B.1.617.20.000075
ORF1ab/nsp2596A596VgCtgTt1616B.10.000147
ORF1ab/nsp2596A596VgCtgTt1212AY.1030.000075
ORF1ab/nsp2596A596VgCtgTt1212B.1.1.700.004093
ORF1ab/nsp2596A596VgCtgTt1212B.1.1770.000158
ORF1ab/nsp2596A596VgCtgTt1111B.1.4290.000259
ORF1ab/nsp2596A596VgCtgTt99B.1.1.3740.021378
ORF1ab/nsp2596A596VgCtgTt99P.10.000142
ORF1ab/nsp2596A596VgCtgTt88AY.250.000048
ORF1ab/nsp2596A596VgCtgTt88B.1.466.20.00313
ORF1ab/nsp2596A596VgCtgTt88B.1.5960.000697
ORF1ab/nsp2596A596VgCtgTt77B.1.20.000062
ORF1ab/nsp2596A596VgCtgTt66AY.260.00017
ORF1ab/nsp2596A596VgCtgTt66AY.430.000027
ORF1ab/nsp2596A596VgCtgTt66B.1.1.5190.000238
ORF1ab/nsp2596A596VgCtgTt66B.1.351.30.005259
ORF1ab/nsp2596A596VgCtgTt66P.1.140.000287
ORF1ab/nsp2596A596VgCtgTt55AY.920.001436
ORF1ab/nsp2596A596VgCTgTC240.111111
ORF1ab/nsp2596A596VgCtgTt240.111111
ORF1ab/nsp2596A596VgCtgTt44AY.1000.000184
ORF1ab/nsp2596A596VgCtgTt44AY.5.10.015038
ORF1ab/nsp2596A596VgCtgTt44AY.590.002119
ORF1ab/nsp2596A596VgCtgTt44B.1.10.000073
ORF1ab/nsp2596A596VgCtgTt44B.1.258.170.000416
ORF1ab/nsp2596A596VgCtgTt33AY.440.000018
ORF1ab/nsp2596A596VgCtgTt33AY.46.60.000217
ORF1ab/nsp2596A596VgCtgTt33AY.750.000168
ORF1ab/nsp2596A596VgCtgTt33AY.910.002191
ORF1ab/nsp2596A596VgCtgTt33B.1.1260.003827
ORF1ab/nsp2596A596VgCtgTt33B.1.2600.010033
ORF1ab/nsp2596A596VgCtgTt33Q.80.000495
ORF1ab/nsp2596A596VgCtgTt22A.2.50.000998
ORF1ab/nsp2596A596VgCtgTt22AY.1020.000053
ORF1ab/nsp2596A596VgCtgTt22AY.450.000243
ORF1ab/nsp2596A596VgCtgTt22AY.540.000191
ORF1ab/nsp2596A596VgCtgTt22AY.99.20.000184
ORF1ab/nsp2596A596VgCtgTt22B.1.1.3850.008929
ORF1ab/nsp2596A596VgCtgTt22B.1.4590.008163
ORF1ab/nsp2596A596VgCtgTt22B.1.5950.000522
ORF1ab/nsp2596A596VgCtgTt22P.1.20.002312
ORF1ab/nsp2596A596VgCtgTt11A0.000387
ORF1ab/nsp2596A596VgCtgTt11A.10.000282
ORF1ab/nsp2596A596VgCtgTt11A.270.001656
ORF1ab/nsp2596A596VgCtgTt11AY.140.000088
ORF1ab/nsp2596A596VgCtgTt11AY.200.000039
ORF1ab/nsp2596A596VgCtgTt11AY.290.000016
ORF1ab/nsp2596A596VgCtgTt11AY.29.10.000221
ORF1ab/nsp2596A596VgCtgTt11AY.30.00001
ORF1ab/nsp2596A596VgCtgTt11AY.300.000396
ORF1ab/nsp2596A596VgCtgTt11AY.460.000104
ORF1ab/nsp2596A596VgCtgTt11AY.46.50.000198
ORF1ab/nsp2596A596VgCtgTt11AY.75.10.00018
ORF1ab/nsp2596A596VgCtgTt11AY.9.20.000037
ORF1ab/nsp2596A596VgCtgTt11AY.9.2.10.001976
ORF1ab/nsp2596A596VgCtgTt11AY.980.000079
ORF1ab/nsp2596A596VgCtgTt11AY.98.10.000048
ORF1ab/nsp2596A596VgCtgTt11B0.000128
ORF1ab/nsp2596A596VgCtgTt11B.1.1.10.000327
ORF1ab/nsp2596A596VgCtgTt11B.1.1.1290.009174
ORF1ab/nsp2596A596VgCtgTt11B.1.1.1860.003436
ORF1ab/nsp2596A596VgCtgTt11B.1.1.2220.000204
ORF1ab/nsp2596A596VgCtgTt11B.1.1.2690.001353
ORF1ab/nsp2596A596VgCtgTt11B.1.1.3170.000412
ORF1ab/nsp2596A596VgCtgTt11B.1.1.3260.001761
ORF1ab/nsp2596A596VgCtgTt11B.1.1.4860.001577
ORF1ab/nsp2596A596VgCtgTt11B.1.1600.000031
ORF1ab/nsp2596A596VgCtgTt11B.1.177.40.000211
ORF1ab/nsp2596A596VgCtgTt11B.1.177.560.000668
ORF1ab/nsp2596A596VgCtgTt11B.1.177.570.000281
ORF1ab/nsp2596A596VgCtgTt11B.1.2220.001692
ORF1ab/nsp2596A596VgCtgTt11B.1.2400.000216
ORF1ab/nsp2596A596VgCtgTt11B.1.3510.00003
ORF1ab/nsp2596A596VgCtgTt11B.1.360.000146
ORF1ab/nsp2596A596VgCtgTt11B.1.36.310.001751
ORF1ab/nsp2596A596VgCtgTt11B.1.36.70.004
ORF1ab/nsp2596A596VgCtgTt11B.1.36.80.001
ORF1ab/nsp2596A596VgCtgTt11B.1.4620.007246
ORF1ab/nsp2596A596VgCtgTt11B.1.5260.000024
ORF1ab/nsp2596A596VgCtgTt11B.1.5740.002151
ORF1ab/nsp2596A596VgCtgTt11B.1.575.10.002439
ORF1ab/nsp2596A596VgCtgTt11B.400.000364
ORF1ab/nsp2596A596VgCtgTt11C.160.00106
ORF1ab/nsp2596A596VgCtgTt11D.20.000075
ORF1ab/nsp2596A596VgCtgTt11P.1.150.000232
ORF1ab/nsp2596A596VgCtgTt11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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