CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = A419V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2419A419VA599VnonsyngCcgTc39321392910.9992372060-2062
ORF1ab/nsp2419A419VA599VnonsyngCCgTT39321290.0007375192060-2062
ORF1ab/nsp2419A419VA599VnonsyngCCgTA3932110.00002543172060-2062

Details of the mutation A419V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2419A419VgCcgTc3929139321All0.007515
ORF1ab/nsp2419A419VgCCgTT2939321All0.000006
ORF1ab/nsp2419A419VgCCgTA139321All0
ORF1ab/nsp2419A419VgCcgTc2365123668AY.200.919199
ORF1ab/nsp2419A419VgCCgTT1723668AY.200.000661
ORF1ab/nsp2419A419VgCcgTc1200212004B.1.1.70.010744
ORF1ab/nsp2419A419VgCCgTT212004B.1.1.70.000002
ORF1ab/nsp2419A419VgCcgTc529532AY.40.000823
ORF1ab/nsp2419A419VgCCgTT3532AY.40.000005
ORF1ab/nsp2419A419VgCcgTc483483B.1.617.20.001819
ORF1ab/nsp2419A419VgCcgTc361361AY.250.002171
ORF1ab/nsp2419A419VgCcgTc227227AY.1130.032322
ORF1ab/nsp2419A419VgCcgTc175177P.30.279107
ORF1ab/nsp2419A419VgCCgTT2177P.30.00319
ORF1ab/nsp2419A419VgCcgTc113115P.10.00178
ORF1ab/nsp2419A419VgCCgTT2115P.10.000032
ORF1ab/nsp2419A419VgCcgTc9292B.1.1600.002869
ORF1ab/nsp2419A419VgCcgTc8686AY.430.000381
ORF1ab/nsp2419A419VgCcgTc7880AY.440.000475
ORF1ab/nsp2419A419VgCCgTT180AY.440.000006
ORF1ab/nsp2419A419VgCCgTA180AY.440.000006
ORF1ab/nsp2419A419VgCcgTc7979B.1.20.000696
ORF1ab/nsp2419A419VgCcgTc7474B.10.000678
ORF1ab/nsp2419A419VgCcgTc6565B.1.1.5190.002581
ORF1ab/nsp2419A419VgCcgTc6262AY.9.20.002277
ORF1ab/nsp2419A419VgCcgTc5959B.1.2430.004105
ORF1ab/nsp2419A419VgCcgTc4849AY.1030.000298
ORF1ab/nsp2419A419VgCCgTT149AY.1030.000006
ORF1ab/nsp2419A419VgCcgTc4949AY.260.001387
ORF1ab/nsp2419A419VgCcgTc4949Q.80.00808
ORF1ab/nsp2419A419VgCcgTc4343B.1.10.00078
ORF1ab/nsp2419A419VgCcgTc3535AY.1190.001236
ORF1ab/nsp2419A419VgCcgTc3434B.1.5260.000799
ORF1ab/nsp2419A419VgCcgTc3131AY.470.000964
ORF1ab/nsp2419A419VgCcgTc3131AY.50.00064
ORF1ab/nsp2419A419VgCcgTc2930C.350.022446
ORF1ab/nsp2419A419VgCCgTT130C.350.000774
ORF1ab/nsp2419A419VgCcgTc2727AY.1170.002282
ORF1ab/nsp2419A419VgCcgTc2727AY.39.10.00107
ORF1ab/nsp2419A419VgCcgTc2727B.1.1770.000356
ORF1ab/nsp2419A419VgCcgTc2525AY.450.003042
ORF1ab/nsp2419A419VgCcgTc2424B.1.3850.255319
ORF1ab/nsp2419A419VgCcgTc2020A.270.033113
ORF1ab/nsp2419A419VgCcgTc2020AY.360.002964
ORF1ab/nsp2419A419VgCcgTc1818AY.240.007759
ORF1ab/nsp2419A419VgCcgTc1818AY.420.000724
ORF1ab/nsp2419A419VgCcgTc1818B.1.4090.014063
ORF1ab/nsp2419A419VgCcgTc1717P.1.140.000813
ORF1ab/nsp2419A419VgCcgTc1616B.1.1.2220.003264
ORF1ab/nsp2419A419VgCcgTc1515AZ.20.012315
ORF1ab/nsp2419A419VgCcgTc1515B.1.177.860.002752
ORF1ab/nsp2419A419VgCcgTc1515Q.10.001895
ORF1ab/nsp2419A419VgCcgTc1414AY.920.004022
ORF1ab/nsp2419A419VgCcgTc1313AY.290.000205
ORF1ab/nsp2419A419VgCcgTc1313B.1.4290.000306
ORF1ab/nsp2419A419VgCcgTc1313B.1.5960.001133
ORF1ab/nsp2419A419VgCcgTc1313B.1.6210.001151
ORF1ab/nsp2419A419VgCcgTc1212AY.1040.02381
ORF1ab/nsp2419A419VgCcgTc1212AY.540.001144
ORF1ab/nsp2419A419VgCcgTc1010B.1.2210.00071
ORF1ab/nsp2419A419VgCcgTc1010C.370.001161
ORF1ab/nsp2419A419VgCcgTc99AY.230.000628
ORF1ab/nsp2419A419VgCcgTc88B.1.3510.000238
ORF1ab/nsp2419A419VgCcgTc77AY.380.003495
ORF1ab/nsp2419A419VgCcgTc77AY.46.60.000505
ORF1ab/nsp2419A419VgCcgTc77B0.000895
ORF1ab/nsp2419A419VgCcgTc77B.1.360.001021
ORF1ab/nsp2419A419VgCcgTc77B.1.36.290.003621
ORF1ab/nsp2419A419VgCcgTc77B.1.4270.000353
ORF1ab/nsp2419A419VgCcgTc77B.1.466.20.002739
ORF1ab/nsp2419A419VgCcgTc77B.1.619.10.00449
ORF1ab/nsp2419A419VgCcgTc77B.1.6370.000512
ORF1ab/nsp2419A419VgCcgTc66B.1.1.3170.00247
ORF1ab/nsp2419A419VgCcgTc66L.30.021277
ORF1ab/nsp2419A419VgCcgTc66P.1.40.005859
ORF1ab/nsp2419A419VgCcgTc66P.20.00112
ORF1ab/nsp2419A419VgCcgTc55A.10.001409
ORF1ab/nsp2419A419VgCcgTc55AD.20.001095
ORF1ab/nsp2419A419VgCcgTc55AY.4.20.000108
ORF1ab/nsp2419A419VgCcgTc55AY.460.00052
ORF1ab/nsp2419A419VgCcgTc55B.1.1.2140.000277
ORF1ab/nsp2419A419VgCcgTc55B.1.1.3220.04386
ORF1ab/nsp2419A419VgCcgTc55B.60.00455
ORF1ab/nsp2419A419VgCcgTc55Q.40.002274
ORF1ab/nsp2419A419VgCcgTc44A.2.50.001996
ORF1ab/nsp2419A419VgCcgTc44AY.1200.000149
ORF1ab/nsp2419A419VgCcgTc44AY.330.000267
ORF1ab/nsp2419A419VgCcgTc44AY.410.001176
ORF1ab/nsp2419A419VgCcgTc44AY.750.000224
ORF1ab/nsp2419A419VgCcgTc44AY.99.20.000369
ORF1ab/nsp2419A419VgCcgTc44B.1.1.3540.017544
ORF1ab/nsp2419A419VgCcgTc44B.1.177.450.001525
ORF1ab/nsp2419A419VgCcgTc44B.1.2580.000266
ORF1ab/nsp2419A419VgCcgTc44B.1.3890.004008
ORF1ab/nsp2419A419VgCcgTc33AY.1000.000138
ORF1ab/nsp2419A419VgCcgTc33AY.1020.00008
ORF1ab/nsp2419A419VgCcgTc33AY.1180.000188
ORF1ab/nsp2419A419VgCcgTc33AY.120.2.10.001495
ORF1ab/nsp2419A419VgCcgTc33AY.30.00003
ORF1ab/nsp2419A419VgCcgTc33AY.390.000074
ORF1ab/nsp2419A419VgCcgTc33AY.700.000626
ORF1ab/nsp2419A419VgCcgTc33B.1.1.1890.004539
ORF1ab/nsp2419A419VgCcgTc33B.1.1110.003525
ORF1ab/nsp2419A419VgCcgTc33B.1.177.570.000843
ORF1ab/nsp2419A419VgCcgTc33B.1.177.600.000655
ORF1ab/nsp2419A419VgCcgTc33B.1.2340.000396
ORF1ab/nsp2419A419VgCcgTc33B.1.2400.000647
ORF1ab/nsp2419A419VgCcgTc33B.1.36.180.001261
ORF1ab/nsp2419A419VgCcgTc33B.1.3690.000856
ORF1ab/nsp2419A419VgCcgTc33B.1.438.10.000322
ORF1ab/nsp2419A419VgCcgTc33B.1.4970.000944
ORF1ab/nsp2419A419VgCcgTc33B.1.5250.000339
ORF1ab/nsp2419A419VgCcgTc33D.20.000225
ORF1ab/nsp2419A419VgCcgTc33P.1.150.000697
ORF1ab/nsp2419A419VgCcgTc22A.2.5.20.003145
ORF1ab/nsp2419A419VgCcgTc22AY.1100.000225
ORF1ab/nsp2419A419VgCcgTc22AY.1110.000366
ORF1ab/nsp2419A419VgCcgTc22AY.1210.000271
ORF1ab/nsp2419A419VgCcgTc22AY.4.50.000215
ORF1ab/nsp2419A419VgCcgTc22AY.530.000575
ORF1ab/nsp2419A419VgCcgTc22AY.690.000373
ORF1ab/nsp2419A419VgCcgTc22AY.930.000546
ORF1ab/nsp2419A419VgCcgTc22AY.980.000158
ORF1ab/nsp2419A419VgCcgTc22AY.98.10.000097
ORF1ab/nsp2419A419VgCcgTc22B.1.1.2160.001781
ORF1ab/nsp2419A419VgCcgTc22B.1.1.280.000622
ORF1ab/nsp2419A419VgCcgTc22B.1.1.330.000842
ORF1ab/nsp2419A419VgCcgTc22B.1.1.370.000386
ORF1ab/nsp2419A419VgCcgTc22B.1.1.830.00542
ORF1ab/nsp2419A419VgCcgTc22B.1.177.440.001038
ORF1ab/nsp2419A419VgCcgTc22B.1.177.760.004988
ORF1ab/nsp2419A419VgCcgTc22B.1.214.20.001199
ORF1ab/nsp2419A419VgCcgTc22B.1.258.70.003824
ORF1ab/nsp2419A419VgCcgTc22B.1.351.20.000605
ORF1ab/nsp2419A419VgCcgTc22B.1.36.10.002281
ORF1ab/nsp2419A419VgCcgTc22B.1.3750.001639
ORF1ab/nsp2419A419VgCcgTc22B.1.4130.008511
ORF1ab/nsp2419A419VgCcgTc22B.1.4560.006536
ORF1ab/nsp2419A419VgCcgTc22B.1.5510.002581
ORF1ab/nsp2419A419VgCcgTc22B.1.5950.000522
ORF1ab/nsp2419A419VgCcgTc22B.1.6200.001892
ORF1ab/nsp2419A419VgCcgTc22P.1.100.000539
ORF1ab/nsp2419A419VgCcgTc22P.1.120.000968
ORF1ab/nsp2419A419VgCcgTc22P.1.70.000639
ORF1ab/nsp2419A419VgCcgTc22R.10.00018
ORF1ab/nsp2419A419VgCcgTc11A.20.000662
ORF1ab/nsp2419A419VgCcgTc11A.23.10.000704
ORF1ab/nsp2419A419VgCcgTc11AU.10.001266
ORF1ab/nsp2419A419VgCcgTc11AY.120.000316
ORF1ab/nsp2419A419VgCcgTc11AY.120.10.000321
ORF1ab/nsp2419A419VgCcgTc11AY.140.000088
ORF1ab/nsp2419A419VgCcgTc11AY.23.10.000417
ORF1ab/nsp2419A419VgCcgTc11AY.270.000065
ORF1ab/nsp2419A419VgCcgTc11AY.300.000396
ORF1ab/nsp2419A419VgCcgTc11AY.340.000097
ORF1ab/nsp2419A419VgCcgTc11AY.4.30.000842
ORF1ab/nsp2419A419VgCcgTc11AY.400.000964
ORF1ab/nsp2419A419VgCcgTc11AY.46.20.000635
ORF1ab/nsp2419A419VgCcgTc11AY.5.30.000337
ORF1ab/nsp2419A419VgCcgTc11AY.5.40.000277
ORF1ab/nsp2419A419VgCcgTc11AY.510.000909
ORF1ab/nsp2419A419VgCcgTc11AY.580.000907
ORF1ab/nsp2419A419VgCcgTc11AY.590.00053
ORF1ab/nsp2419A419VgCcgTc11AY.610.000105
ORF1ab/nsp2419A419VgCcgTc11AY.680.000274
ORF1ab/nsp2419A419VgCcgTc11AY.7.10.000113
ORF1ab/nsp2419A419VgCcgTc11AY.710.000475
ORF1ab/nsp2419A419VgCcgTc11AY.75.10.00018
ORF1ab/nsp2419A419VgCcgTc11AY.820.001357
ORF1ab/nsp2419A419VgCcgTc11AY.830.001724
ORF1ab/nsp2419A419VgCcgTc11AY.9.10.000084
ORF1ab/nsp2419A419VgCcgTc11AY.950.000761
ORF1ab/nsp2419A419VgCcgTc11B.1.1.10.000327
ORF1ab/nsp2419A419VgCcgTc11B.1.1.1340.011364
ORF1ab/nsp2419A419VgCcgTc11B.1.1.1410.002012
ORF1ab/nsp2419A419VgCcgTc11B.1.1.1610.003534
ORF1ab/nsp2419A419VgCcgTc11B.1.1.1740.003378
ORF1ab/nsp2419A419VgCcgTc11B.1.1.1760.000439
ORF1ab/nsp2419A419VgCcgTc11B.1.1.2070.001182
ORF1ab/nsp2419A419VgCcgTc11B.1.1.2200.001859
ORF1ab/nsp2419A419VgCcgTc11B.1.1.2730.006757
ORF1ab/nsp2419A419VgCcgTc11B.1.1.2800.003086
ORF1ab/nsp2419A419VgCcgTc11B.1.1.3040.002809
ORF1ab/nsp2419A419VgCcgTc11B.1.1.3110.000358
ORF1ab/nsp2419A419VgCcgTc11B.1.1.3160.000925
ORF1ab/nsp2419A419VgCcgTc11B.1.1.3690.000446
ORF1ab/nsp2419A419VgCcgTc11B.1.1.3730.02381
ORF1ab/nsp2419A419VgCcgTc11B.1.1.4200.001006
ORF1ab/nsp2419A419VgCcgTc11B.1.1.4340.000349
ORF1ab/nsp2419A419VgCcgTc11B.1.1.450.014085
ORF1ab/nsp2419A419VgCcgTc11B.1.1.4500.034483
ORF1ab/nsp2419A419VgCcgTc11B.1.1.700.000341
ORF1ab/nsp2419A419VgCcgTc11B.1.110.30.000718
ORF1ab/nsp2419A419VgCcgTc11B.1.177.150.000631
ORF1ab/nsp2419A419VgCcgTc11B.1.177.210.000076
ORF1ab/nsp2419A419VgCcgTc11B.1.177.330.001645
ORF1ab/nsp2419A419VgCcgTc11B.1.177.340.052632
ORF1ab/nsp2419A419VgCcgTc11B.1.177.530.002392
ORF1ab/nsp2419A419VgCcgTc11B.1.177.540.000606
ORF1ab/nsp2419A419VgCcgTc11B.1.177.560.000668
ORF1ab/nsp2419A419VgCcgTc11B.1.177.580.001332
ORF1ab/nsp2419A419VgCcgTc11B.1.177.60.000977
ORF1ab/nsp2419A419VgCcgTc11B.1.177.730.000566
ORF1ab/nsp2419A419VgCcgTc11B.1.177.820.000477
ORF1ab/nsp2419A419VgCcgTc11B.1.1890.004292
ORF1ab/nsp2419A419VgCcgTc11B.1.221.10.002907
ORF1ab/nsp2419A419VgCcgTc11B.1.258.110.000396
ORF1ab/nsp2419A419VgCcgTc11B.1.258.140.00098
ORF1ab/nsp2419A419VgCcgTc11B.1.258.170.000104
ORF1ab/nsp2419A419VgCcgTc11B.1.30.002618
ORF1ab/nsp2419A419VgCcgTc11B.1.3500.002933
ORF1ab/nsp2419A419VgCcgTc11B.1.3670.000792
ORF1ab/nsp2419A419VgCcgTc11B.1.3970.004854
ORF1ab/nsp2419A419VgCcgTc11B.1.4000.000429
ORF1ab/nsp2419A419VgCcgTc11B.1.416.10.001563
ORF1ab/nsp2419A419VgCcgTc11B.1.4260.001009
ORF1ab/nsp2419A419VgCcgTc11B.1.428.30.012821
ORF1ab/nsp2419A419VgCcgTc11B.1.4450.011765
ORF1ab/nsp2419A419VgCcgTc11B.1.4660.023256
ORF1ab/nsp2419A419VgCcgTc11B.1.4700.001404
ORF1ab/nsp2419A419VgCcgTc11B.1.5230.002451
ORF1ab/nsp2419A419VgCcgTc11B.1.5400.009709
ORF1ab/nsp2419A419VgCcgTc11B.1.5410.004425
ORF1ab/nsp2419A419VgCcgTc11B.1.5600.00463
ORF1ab/nsp2419A419VgCcgTc11B.1.5640.000426
ORF1ab/nsp2419A419VgCcgTc11B.1.5650.00081
ORF1ab/nsp2419A419VgCcgTc11B.1.5680.001111
ORF1ab/nsp2419A419VgCcgTc11B.1.5760.000907
ORF1ab/nsp2419A419VgCcgTc11B.1.5970.00463
ORF1ab/nsp2419A419VgCcgTc11B.1.617.10.000129
ORF1ab/nsp2419A419VgCcgTc11B.1.617.30.002985
ORF1ab/nsp2419A419VgCcgTc11B.230.002924
ORF1ab/nsp2419A419VgCcgTc11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.