CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 63

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp263E63EE243EsyngaAgaG9389381992-994
ORF1ab/nsp263E63KE243KnonsynGaaAaa1661661992-994
ORF1ab/nsp263E63GE243GnonsyngAagGa80801992-994
ORF1ab/nsp263E63AE243AnonsyngAagCa55551992-994
ORF1ab/nsp263E63DE243DnonsyngaAgaC29240.827586992-994
ORF1ab/nsp263E63DE243DnonsyngaAgaT2950.172414992-994
ORF1ab/nsp263E63delE243deldelGAA---27271992-994
ORF1ab/nsp263E63VE243VnonsyngAagTa10101992-994
ORF1ab/nsp263E63QE243QnonsynGaaCaa331992-994
ORF1ab/nsp263E63XE243XnonsynGaaTaa331992-994

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp263E63EgaAgaG938938All0.000179
ORF1ab/nsp263E63EgaAgaG481481B.1.6270.971717
ORF1ab/nsp263E63EgaAgaG292292B.1.6310.983165
ORF1ab/nsp263E63KGaaAaa166166All0.000032
ORF1ab/nsp263E63GgAagGa8080All0.000015
ORF1ab/nsp263E63KGaaAaa6161B.1.1.70.000055
ORF1ab/nsp263E63EgaAgaG5757B.1.1.70.000051
ORF1ab/nsp263E63AgAagCa5555All0.000011
ORF1ab/nsp263E63DgaAgaC2429All0.000005
ORF1ab/nsp263E63DgaAgaT529All0.000001
ORF1ab/nsp263E63delGAA---2727All0.000005
ORF1ab/nsp263E63GgAagGa2222B.1.1.70.00002
ORF1ab/nsp263E63KGaaAaa2020AY.40.000031
ORF1ab/nsp263E63GgAagGa1919AY.250.000114
ORF1ab/nsp263E63AgAagCa1515B.1.617.20.000056
ORF1ab/nsp263E63EgaAgaG1414B.10.000128
ORF1ab/nsp263E63AgAagCa1111B.1.1.70.00001
ORF1ab/nsp263E63VgAagTa1010All0.000002
ORF1ab/nsp263E63EgaAgaG1010B.1.1.370.001929
ORF1ab/nsp263E63DgaAgaC1010B.1.20.000088
ORF1ab/nsp263E63KGaaAaa1010B.1.20.000088
ORF1ab/nsp263E63EgaAgaG99B.1.20.000079
ORF1ab/nsp263E63EgaAgaG99B.1.617.20.000034
ORF1ab/nsp263E63KGaaAaa99B.1.617.20.000034
ORF1ab/nsp263E63KGaaAaa77AY.290.00011
ORF1ab/nsp263E63KGaaAaa77B.1.10.000127
ORF1ab/nsp263E63EgaAgaG66AY.250.000036
ORF1ab/nsp263E63EgaAgaG66B0.000767
ORF1ab/nsp263E63EgaAgaG55AY.430.000022
ORF1ab/nsp263E63delGAA---55B.1.1.330.002104
ORF1ab/nsp263E63delGAA---55B.1.1.70.000004
ORF1ab/nsp263E63GgAagGa55P.10.000079
ORF1ab/nsp263E63KGaaAaa55Q.10.000632
ORF1ab/nsp263E63DgaAgaT34AY.250.000018
ORF1ab/nsp263E63DgaAgaC14AY.250.000006
ORF1ab/nsp263E63KGaaAaa44AY.440.000024
ORF1ab/nsp263E63EgaAgaG44B.1.1.2530.010025
ORF1ab/nsp263E63delGAA---44B.1.1.3480.003185
ORF1ab/nsp263E63KGaaAaa33A.23.10.002113
ORF1ab/nsp263E63QGaaCaa33All0.000001
ORF1ab/nsp263E63XGaaTaa33All0.000001
ORF1ab/nsp263E63KGaaAaa33AY.250.000018
ORF1ab/nsp263E63AgAagCa33AY.290.000047
ORF1ab/nsp263E63KGaaAaa33AY.30.00003
ORF1ab/nsp263E63EgaAgaG33AY.390.000074
ORF1ab/nsp263E63EgaAgaG33AY.40.000005
ORF1ab/nsp263E63GgAagGa33AY.40.000005
ORF1ab/nsp263E63GgAagGa33AY.440.000018
ORF1ab/nsp263E63EgaAgaG33B.1.4290.000071
ORF1ab/nsp263E63EgaAgaG22A.2.50.000998
ORF1ab/nsp263E63GgAagGa22AY.1030.000012
ORF1ab/nsp263E63GgAagGa22AY.120.10.000642
ORF1ab/nsp263E63AgAagCa22AY.250.000012
ORF1ab/nsp263E63EgaAgaG22AY.30.00002
ORF1ab/nsp263E63DgaAgaC22AY.3.10.000171
ORF1ab/nsp263E63AgAagCa22AY.40.000003
ORF1ab/nsp263E63DgaAgaC22AY.40.000003
ORF1ab/nsp263E63GgAagGa22AY.4.20.000043
ORF1ab/nsp263E63AgAagCa22AY.70.000392
ORF1ab/nsp263E63DgaAgaC22AY.780.003082
ORF1ab/nsp263E63XGaaTaa22B.10.000018
ORF1ab/nsp263E63EgaAgaG22B.1.1.5190.000079
ORF1ab/nsp263E63GgAagGa22B.1.1.5190.000079
ORF1ab/nsp263E63DgaAgaC22B.1.1.70.000002
ORF1ab/nsp263E63KGaaAaa22B.1.2210.000142
ORF1ab/nsp263E63KGaaAaa22B.1.2430.000139
ORF1ab/nsp263E63AgAagCa22B.1.258.140.001961
ORF1ab/nsp263E63EgaAgaG22B.1.3510.000059
ORF1ab/nsp263E63EgaAgaG22B.1.4000.000858
ORF1ab/nsp263E63KGaaAaa22B.1.5260.000047
ORF1ab/nsp263E63VgAagTa22B.1.617.20.000008
ORF1ab/nsp263E63GgAagGa22B.1.617.20.000008
ORF1ab/nsp263E63DgaAgaC12B.1.617.20.000004
ORF1ab/nsp263E63DgaAgaT12B.1.617.20.000004
ORF1ab/nsp263E63AgAagCa22B.1.6210.000177
ORF1ab/nsp263E63delGAA---22N.40.008511
ORF1ab/nsp263E63delGAA---22N.60.014184
ORF1ab/nsp263E63delGAA---22P.20.000373
ORF1ab/nsp263E63GgAagGa110.055556
ORF1ab/nsp263E63GgAagGa11A.23.10.000704
ORF1ab/nsp263E63KGaaAaa11AD.20.000219
ORF1ab/nsp263E63EgaAgaG11AU.30.00211
ORF1ab/nsp263E63EgaAgaG11AY.1000.000046
ORF1ab/nsp263E63KGaaAaa11AY.1020.000027
ORF1ab/nsp263E63KGaaAaa11AY.1030.000006
ORF1ab/nsp263E63AgAagCa11AY.1030.000006
ORF1ab/nsp263E63EgaAgaG11AY.1030.000006
ORF1ab/nsp263E63delGAA---11AY.1110.000183
ORF1ab/nsp263E63GgAagGa11AY.1180.000063
ORF1ab/nsp263E63KGaaAaa11AY.120.000316
ORF1ab/nsp263E63VgAagTa11AY.200.000039
ORF1ab/nsp263E63EgaAgaG11AY.230.00007
ORF1ab/nsp263E63KGaaAaa11AY.230.00007
ORF1ab/nsp263E63VgAagTa11AY.250.000006
ORF1ab/nsp263E63GgAagGa11AY.260.000028
ORF1ab/nsp263E63EgaAgaG11AY.270.000065
ORF1ab/nsp263E63GgAagGa11AY.30.00001
ORF1ab/nsp263E63AgAagCa11AY.360.000148
ORF1ab/nsp263E63AgAagCa11AY.390.000025
ORF1ab/nsp263E63KGaaAaa11AY.390.000025
ORF1ab/nsp263E63GgAagGa11AY.390.000025
ORF1ab/nsp263E63EgaAgaG11AY.39.10.00004
ORF1ab/nsp263E63AgAagCa11AY.39.10.00004
ORF1ab/nsp263E63delGAA---11AY.40.000002
ORF1ab/nsp263E63QGaaCaa11AY.40.000002
ORF1ab/nsp263E63EgaAgaG11AY.4.50.000107
ORF1ab/nsp263E63GgAagGa11AY.420.00004
ORF1ab/nsp263E63DgaAgaC11AY.420.00004
ORF1ab/nsp263E63KGaaAaa11AY.420.00004
ORF1ab/nsp263E63VgAagTa11AY.430.000004
ORF1ab/nsp263E63KGaaAaa11AY.430.000004
ORF1ab/nsp263E63EgaAgaG11AY.440.000006
ORF1ab/nsp263E63AgAagCa11AY.440.000006
ORF1ab/nsp263E63KGaaAaa11AY.460.000104
ORF1ab/nsp263E63EgaAgaG11AY.460.000104
ORF1ab/nsp263E63AgAagCa11AY.470.000031
ORF1ab/nsp263E63GgAagGa11AY.50.000021
ORF1ab/nsp263E63KGaaAaa11AY.50.000021
ORF1ab/nsp263E63AgAagCa11AY.610.000105
ORF1ab/nsp263E63EgaAgaG11AY.610.000105
ORF1ab/nsp263E63DgaAgaC11AY.610.000105
ORF1ab/nsp263E63DgaAgaC11AY.650.000533
ORF1ab/nsp263E63AgAagCa11AY.670.000464
ORF1ab/nsp263E63KGaaAaa11AY.7.10.000113
ORF1ab/nsp263E63VgAagTa11AY.710.000475
ORF1ab/nsp263E63AgAagCa11AY.800.001129
ORF1ab/nsp263E63AgAagCa11AY.850.000427
ORF1ab/nsp263E63KGaaAaa11AY.90.000068
ORF1ab/nsp263E63GgAagGa11AY.90.000068
ORF1ab/nsp263E63EgaAgaG11AY.910.00073
ORF1ab/nsp263E63GgAagGa11AY.980.000079
ORF1ab/nsp263E63AgAagCa11B.10.000009
ORF1ab/nsp263E63KGaaAaa11B.10.000009
ORF1ab/nsp263E63DgaAgaT11B.10.000009
ORF1ab/nsp263E63GgAagGa11B.1.10.000018
ORF1ab/nsp263E63EgaAgaG11B.1.10.000018
ORF1ab/nsp263E63AgAagCa11B.1.10.000018
ORF1ab/nsp263E63EgaAgaG11B.1.1.10.000327
ORF1ab/nsp263E63EgaAgaG11B.1.1.1530.001095
ORF1ab/nsp263E63KGaaAaa11B.1.1.1980.001468
ORF1ab/nsp263E63KGaaAaa11B.1.1.2910.000742
ORF1ab/nsp263E63EgaAgaG11B.1.1.3110.000358
ORF1ab/nsp263E63GgAagGa11B.1.1.3690.000446
ORF1ab/nsp263E63VgAagTa11B.1.1.70.000001
ORF1ab/nsp263E63KGaaAaa11B.1.1600.000031
ORF1ab/nsp263E63GgAagGa11B.1.1600.000031
ORF1ab/nsp263E63EgaAgaG11B.1.1600.000031
ORF1ab/nsp263E63VgAagTa11B.1.1770.000013
ORF1ab/nsp263E63AgAagCa11B.1.1770.000013
ORF1ab/nsp263E63KGaaAaa11B.1.1770.000013
ORF1ab/nsp263E63AgAagCa11B.1.177.230.003236
ORF1ab/nsp263E63KGaaAaa11B.1.177.280.007407
ORF1ab/nsp263E63EgaAgaG11B.1.177.440.000519
ORF1ab/nsp263E63EgaAgaG11B.1.177.600.000218
ORF1ab/nsp263E63EgaAgaG11B.1.177.730.000566
ORF1ab/nsp263E63KGaaAaa11B.1.177.810.000189
ORF1ab/nsp263E63QGaaCaa11B.1.20.000009
ORF1ab/nsp263E63VgAagTa11B.1.20.000009
ORF1ab/nsp263E63EgaAgaG11B.1.2340.000132
ORF1ab/nsp263E63DgaAgaC11B.1.2400.000216
ORF1ab/nsp263E63GgAagGa11B.1.2400.000216
ORF1ab/nsp263E63GgAagGa11B.1.2410.000812
ORF1ab/nsp263E63KGaaAaa11B.1.258.140.00098
ORF1ab/nsp263E63EgaAgaG11B.1.258.170.000104
ORF1ab/nsp263E63XGaaTaa11B.1.351.20.000303
ORF1ab/nsp263E63KGaaAaa11B.1.36.290.000517
ORF1ab/nsp263E63EgaAgaG11B.1.4270.00005
ORF1ab/nsp263E63AgAagCa11B.1.4290.000024
ORF1ab/nsp263E63KGaaAaa11B.1.4290.000024
ORF1ab/nsp263E63delGAA---11B.1.4290.000024
ORF1ab/nsp263E63KGaaAaa11B.1.466.20.000391
ORF1ab/nsp263E63VgAagTa11B.1.5950.000261
ORF1ab/nsp263E63KGaaAaa11B.1.5960.000087
ORF1ab/nsp263E63delGAA---11B.1.617.20.000004
ORF1ab/nsp263E63delGAA---11B.1.617.30.002985
ORF1ab/nsp263E63EgaAgaG11B.1.6280.000352
ORF1ab/nsp263E63EgaAgaG11B.1.6340.003425
ORF1ab/nsp263E63EgaAgaG11B.30.000831
ORF1ab/nsp263E63delGAA---11B.340.013699
ORF1ab/nsp263E63delGAA---11C.350.000774
ORF1ab/nsp263E63KGaaAaa11N.30.005814
ORF1ab/nsp263E63KGaaAaa11P.10.000016
ORF1ab/nsp263E63GgAagGa11P.1.140.000048
ORF1ab/nsp263E63KGaaAaa11P.1.70.000319
ORF1ab/nsp263E63GgAagGa11Q.10.000126
ORF1ab/nsp263E63EgaAgaG11Q.10.000126
ORF1ab/nsp263E63KGaaAaa11Q.80.000165
ORF1ab/nsp263E63AgAagCa11Q.80.000165
ORF1ab/nsp263E63GgAagGa11R.10.00009
ORF1ab/nsp263E63QGaaCaa11Z.10.00289

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.