CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 575

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2575E575KE755KnonsynGaaAaa2434243412528-2530
ORF1ab/nsp2575E575EE755EsyngaAgaG52452412528-2530
ORF1ab/nsp2575E575DE755DnonsyngaAgaT90480.5333332528-2530
ORF1ab/nsp2575E575DE755DnonsyngaAgaC90420.4666672528-2530
ORF1ab/nsp2575E575delE755deldelGAA---656512528-2530
ORF1ab/nsp2575E575GE755GnonsyngAagGa51490.9607842528-2530
ORF1ab/nsp2575E575GE755GnonsyngAAgGG5120.03921572528-2530
ORF1ab/nsp2575E575VE755VnonsyngAagTa414112528-2530
ORF1ab/nsp2575E575AE755AnonsyngAagCa232312528-2530
ORF1ab/nsp2575E575XE755XnonsynGaaTaa1160.5454552528-2530
ORF1ab/nsp2575E575XE755XnonsynGaATaG1140.3636362528-2530
ORF1ab/nsp2575E575XE755XnonsynGAaTGa1110.09090912528-2530
ORF1ab/nsp2575E575QE755QnonsynGaaCaa6612528-2530
ORF1ab/nsp2575E575del1E755del1delgAag-a1112528-2530
ORF1ab/nsp2575E575RE755RnonsynGAACGT1112528-2530

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2575E575KGaaAaa24342434All0.000466
ORF1ab/nsp2575E575KGaaAaa19341934B.1.2790.993323
ORF1ab/nsp2575E575EgaAgaG524524All0.0001
ORF1ab/nsp2575E575EgaAgaG178178B.1.617.20.00067
ORF1ab/nsp2575E575EgaAgaG175175B.1.1.70.000157
ORF1ab/nsp2575E575DgaAgaT4890All0.000009
ORF1ab/nsp2575E575DgaAgaC4290All0.000008
ORF1ab/nsp2575E575KGaaAaa6868B.60.061874
ORF1ab/nsp2575E575delGAA---6565All0.000012
ORF1ab/nsp2575E575EgaAgaG6161AY.1020.001617
ORF1ab/nsp2575E575KGaaAaa5656B.1.1770.000737
ORF1ab/nsp2575E575GgAagGa4951All0.000009
ORF1ab/nsp2575E575GgAAgGG251All0
ORF1ab/nsp2575E575KGaaAaa5050B.1.1.70.000045
ORF1ab/nsp2575E575KGaaAaa4646AY.250.000277
ORF1ab/nsp2575E575VgAagTa4141All0.000008
ORF1ab/nsp2575E575KGaaAaa4141B.1.617.10.005288
ORF1ab/nsp2575E575KGaaAaa2828AY.40.000044
ORF1ab/nsp2575E575AgAagCa2323All0.000004
ORF1ab/nsp2575E575EgaAgaG2121AY.390.000519
ORF1ab/nsp2575E575VgAagTa1919AY.4.50.002042
ORF1ab/nsp2575E575KGaaAaa1818B.10.000165
ORF1ab/nsp2575E575KGaaAaa1818B.1.1.2260.104651
ORF1ab/nsp2575E575delGAA---1515B.1.1.70.000013
ORF1ab/nsp2575E575AgAagCa1414AY.470.000435
ORF1ab/nsp2575E575KGaaAaa1414B.1.3800.092715
ORF1ab/nsp2575E575DgaAgaT1213B.1.4270.000606
ORF1ab/nsp2575E575DgaAgaC113B.1.4270.00005
ORF1ab/nsp2575E575KGaaAaa1212B0.001534
ORF1ab/nsp2575E575XGaaTaa611All0.000001
ORF1ab/nsp2575E575XGaATaG411All0.000001
ORF1ab/nsp2575E575XGAaTGa111All0
ORF1ab/nsp2575E575DgaAgaT1111B.1.5260.000259
ORF1ab/nsp2575E575KGaaAaa1111P.10.000173
ORF1ab/nsp2575E575EgaAgaG1010AY.430.000044
ORF1ab/nsp2575E575GgAagGa1010B.1.1.70.000009
ORF1ab/nsp2575E575DgaAgaC710B.1.1.70.000006
ORF1ab/nsp2575E575DgaAgaT310B.1.1.70.000003
ORF1ab/nsp2575E575KGaaAaa1010B.1.20.000088
ORF1ab/nsp2575E575KGaaAaa1010B.1.617.20.000038
ORF1ab/nsp2575E575KGaaAaa99A0.003483
ORF1ab/nsp2575E575EgaAgaG99AY.1170.000761
ORF1ab/nsp2575E575DgaAgaT79AY.40.000011
ORF1ab/nsp2575E575DgaAgaC29AY.40.000003
ORF1ab/nsp2575E575VgAagTa99B.1.1.70.000008
ORF1ab/nsp2575E575KGaaAaa99B.1.4290.000212
ORF1ab/nsp2575E575KGaaAaa88B.1.1570.023881
ORF1ab/nsp2575E575DgaAgaC77AY.30.00007
ORF1ab/nsp2575E575GgAagGa77B.1.1.2410.014493
ORF1ab/nsp2575E575KGaaAaa77P.20.001306
ORF1ab/nsp2575E575delGAA---660.333333
ORF1ab/nsp2575E575QGaaCaa66All0.000001
ORF1ab/nsp2575E575EgaAgaG66AY.1160.001721
ORF1ab/nsp2575E575KGaaAaa66AY.440.000037
ORF1ab/nsp2575E575VgAagTa66B.1.1.5190.000238
ORF1ab/nsp2575E575DgaAgaC66B.1.177.120.00091
ORF1ab/nsp2575E575DgaAgaC66B.1.5640.002555
ORF1ab/nsp2575E575KGaaAaa55AY.1030.000031
ORF1ab/nsp2575E575EgaAgaG55AY.250.00003
ORF1ab/nsp2575E575GgAagGa55AY.4.20.000108
ORF1ab/nsp2575E575delGAA---55B.10.000046
ORF1ab/nsp2575E575KGaaAaa55B.1.2400.001078
ORF1ab/nsp2575E575DgaAgaT45B.1.617.20.000015
ORF1ab/nsp2575E575DgaAgaC15B.1.617.20.000004
ORF1ab/nsp2575E575EgaAgaG44AY.1030.000025
ORF1ab/nsp2575E575EgaAgaG44AY.620.001743
ORF1ab/nsp2575E575GgAagGa34B.10.000027
ORF1ab/nsp2575E575GgAAgGG14B.10.000009
ORF1ab/nsp2575E575EgaAgaG44P.1.140.000191
ORF1ab/nsp2575E575KGaaAaa33AY.1000.000138
ORF1ab/nsp2575E575EgaAgaG33AY.1190.000106
ORF1ab/nsp2575E575KGaaAaa33AY.200.000117
ORF1ab/nsp2575E575EgaAgaG33AY.40.000005
ORF1ab/nsp2575E575DgaAgaC23AY.430.000009
ORF1ab/nsp2575E575DgaAgaT13AY.430.000004
ORF1ab/nsp2575E575GgAagGa33AY.440.000018
ORF1ab/nsp2575E575EgaAgaG33AY.440.000018
ORF1ab/nsp2575E575EgaAgaG33AY.450.000365
ORF1ab/nsp2575E575EgaAgaG33B.10.000027
ORF1ab/nsp2575E575delGAA---33B.1.1.330.001263
ORF1ab/nsp2575E575DgaAgaT33B.1.1770.00004
ORF1ab/nsp2575E575KGaaAaa33B.1.2210.000213
ORF1ab/nsp2575E575EgaAgaG33B.1.2210.000213
ORF1ab/nsp2575E575KGaaAaa33B.1.5070.033708
ORF1ab/nsp2575E575GgAagGa33B.1.6210.000266
ORF1ab/nsp2575E575KGaaAaa22AY.230.000139
ORF1ab/nsp2575E575EgaAgaG22AY.30.00002
ORF1ab/nsp2575E575KGaaAaa22AY.39.10.000079
ORF1ab/nsp2575E575AgAagCa22AY.40.000003
ORF1ab/nsp2575E575GgAagGa22AY.40.000003
ORF1ab/nsp2575E575EgaAgaG22AY.46.20.001271
ORF1ab/nsp2575E575DgaAgaC22AY.46.40.000329
ORF1ab/nsp2575E575EgaAgaG22AY.46.40.000329
ORF1ab/nsp2575E575EgaAgaG22AY.770.002255
ORF1ab/nsp2575E575EgaAgaG22B.1.10.000036
ORF1ab/nsp2575E575KGaaAaa22B.1.10.000036
ORF1ab/nsp2575E575delGAA---22B.1.10.000036
ORF1ab/nsp2575E575delGAA---22B.1.1.3480.001592
ORF1ab/nsp2575E575KGaaAaa22B.1.1.5190.000079
ORF1ab/nsp2575E575AgAagCa22B.1.1.70.000002
ORF1ab/nsp2575E575DgaAgaC22B.1.20.000018
ORF1ab/nsp2575E575delGAA---22B.1.20.000018
ORF1ab/nsp2575E575KGaaAaa22B.1.2580.000133
ORF1ab/nsp2575E575delGAA---22B.1.4240.016129
ORF1ab/nsp2575E575delGAA---22B.1.4290.000047
ORF1ab/nsp2575E575GgAagGa22B.1.4290.000047
ORF1ab/nsp2575E575KGaaAaa22B.1.4700.002809
ORF1ab/nsp2575E575KGaaAaa22B.1.5050.008772
ORF1ab/nsp2575E575KGaaAaa22B.1.5260.000047
ORF1ab/nsp2575E575KGaaAaa22B.1.5950.000522
ORF1ab/nsp2575E575KGaaAaa22B.1.617.30.00597
ORF1ab/nsp2575E575DgaAgaC22B.1.6210.000177
ORF1ab/nsp2575E575delGAA---22N.60.014184
ORF1ab/nsp2575E575delGAA---22P.10.000032
ORF1ab/nsp2575E575GgAagGa11A.20.000662
ORF1ab/nsp2575E575EgaAgaG11A.2.40.003367
ORF1ab/nsp2575E575VgAagTa11A.2.50.000499
ORF1ab/nsp2575E575KGaaAaa11A.2.5.10.004808
ORF1ab/nsp2575E575del1gAag-a11All0
ORF1ab/nsp2575E575RGAACGT11All0
ORF1ab/nsp2575E575KGaaAaa11AU.30.00211
ORF1ab/nsp2575E575RGAACGT11AY.1010.00049
ORF1ab/nsp2575E575XGaATaG11AY.1010.00049
ORF1ab/nsp2575E575KGaaAaa11AY.1020.000027
ORF1ab/nsp2575E575DgaAgaT11AY.1020.000027
ORF1ab/nsp2575E575GgAagGa11AY.1030.000006
ORF1ab/nsp2575E575KGaaAaa11AY.1060.000335
ORF1ab/nsp2575E575delGAA---11AY.1080.001103
ORF1ab/nsp2575E575GgAagGa11AY.1100.000113
ORF1ab/nsp2575E575delGAA---11AY.1110.000183
ORF1ab/nsp2575E575VgAagTa11AY.1130.000142
ORF1ab/nsp2575E575GgAagGa11AY.1130.000142
ORF1ab/nsp2575E575QGaaCaa11AY.1190.000035
ORF1ab/nsp2575E575KGaaAaa11AY.1190.000035
ORF1ab/nsp2575E575EgaAgaG11AY.1200.000037
ORF1ab/nsp2575E575GgAagGa11AY.1210.000135
ORF1ab/nsp2575E575KGaaAaa11AY.130.000161
ORF1ab/nsp2575E575QGaaCaa11AY.130.000161
ORF1ab/nsp2575E575delGAA---11AY.190.00114
ORF1ab/nsp2575E575DgaAgaT11AY.230.00007
ORF1ab/nsp2575E575delGAA---11AY.240.000431
ORF1ab/nsp2575E575delGAA---11AY.250.000006
ORF1ab/nsp2575E575DgaAgaT11AY.250.000006
ORF1ab/nsp2575E575KGaaAaa11AY.260.000028
ORF1ab/nsp2575E575delGAA---11AY.290.000016
ORF1ab/nsp2575E575KGaaAaa11AY.290.000016
ORF1ab/nsp2575E575GgAagGa11AY.290.000016
ORF1ab/nsp2575E575EgaAgaG11AY.290.000016
ORF1ab/nsp2575E575delGAA---11AY.30.00001
ORF1ab/nsp2575E575KGaaAaa11AY.30.00001
ORF1ab/nsp2575E575KGaaAaa11AY.300.000396
ORF1ab/nsp2575E575DgaAgaC11AY.330.000067
ORF1ab/nsp2575E575EgaAgaG11AY.360.000148
ORF1ab/nsp2575E575VgAagTa11AY.40.000002
ORF1ab/nsp2575E575delGAA---11AY.40.000002
ORF1ab/nsp2575E575KGaaAaa11AY.4.10.000737
ORF1ab/nsp2575E575KGaaAaa11AY.4.20.000022
ORF1ab/nsp2575E575EgaAgaG11AY.4.40.000409
ORF1ab/nsp2575E575delGAA---11AY.4.50.000107
ORF1ab/nsp2575E575delGAA---11AY.420.00004
ORF1ab/nsp2575E575XGaaTaa11AY.430.000004
ORF1ab/nsp2575E575GgAagGa11AY.430.000004
ORF1ab/nsp2575E575XGaaTaa11AY.440.000006
ORF1ab/nsp2575E575VgAagTa11AY.450.000122
ORF1ab/nsp2575E575EgaAgaG11AY.5.40.000277
ORF1ab/nsp2575E575KGaaAaa11AY.530.000288
ORF1ab/nsp2575E575DgaAgaC11AY.550.000917
ORF1ab/nsp2575E575XGaATaG11AY.550.000917
ORF1ab/nsp2575E575delGAA---11AY.60.000041
ORF1ab/nsp2575E575KGaaAaa11AY.610.000105
ORF1ab/nsp2575E575XGaATaG11AY.610.000105
ORF1ab/nsp2575E575EgaAgaG11AY.680.000274
ORF1ab/nsp2575E575XGAaTGa11AY.710.000475
ORF1ab/nsp2575E575KGaaAaa11AY.710.000475
ORF1ab/nsp2575E575GgAagGa11AY.750.000056
ORF1ab/nsp2575E575DgaAgaT11AY.800.001129
ORF1ab/nsp2575E575KGaaAaa11AY.920.000287
ORF1ab/nsp2575E575KGaaAaa11AY.980.000079
ORF1ab/nsp2575E575VgAagTa11AY.98.10.000048
ORF1ab/nsp2575E575EgaAgaG11AY.99.20.000092
ORF1ab/nsp2575E575DgaAgaT11AY.99.20.000092
ORF1ab/nsp2575E575EgaAgaG11B0.000128
ORF1ab/nsp2575E575XGaaTaa11B.10.000009
ORF1ab/nsp2575E575QGaaCaa11B.10.000009
ORF1ab/nsp2575E575AgAagCa11B.10.000009
ORF1ab/nsp2575E575XGaaTaa11B.1.10.000018
ORF1ab/nsp2575E575GgAagGa11B.1.10.000018
ORF1ab/nsp2575E575KGaaAaa11B.1.1.1530.001095
ORF1ab/nsp2575E575KGaaAaa11B.1.1.1700.001247
ORF1ab/nsp2575E575delGAA---11B.1.1.2070.001182
ORF1ab/nsp2575E575KGaaAaa11B.1.1.250.000569
ORF1ab/nsp2575E575GgAagGa11B.1.1.2910.000742
ORF1ab/nsp2575E575EgaAgaG11B.1.1.3090.005848
ORF1ab/nsp2575E575VgAagTa11B.1.1.3180.000302
ORF1ab/nsp2575E575KGaaAaa11B.1.1.3260.001761
ORF1ab/nsp2575E575delGAA---11B.1.1.4160.000905
ORF1ab/nsp2575E575AgAagCa11B.1.1.4420.018519
ORF1ab/nsp2575E575delGAA---11B.1.1.4480.002033
ORF1ab/nsp2575E575DgaAgaC11B.1.1.4480.002033
ORF1ab/nsp2575E575EgaAgaG11B.1.1.500.000679
ORF1ab/nsp2575E575EgaAgaG11B.1.1.5190.00004
ORF1ab/nsp2575E575del1gAag-a11B.1.1.70.000001
ORF1ab/nsp2575E575QGaaCaa11B.1.1.70.000001
ORF1ab/nsp2575E575XGaaTaa11B.1.1.70.000001
ORF1ab/nsp2575E575GgAAgGG11B.1.1570.002985
ORF1ab/nsp2575E575KGaaAaa11B.1.1600.000031
ORF1ab/nsp2575E575GgAagGa11B.1.1770.000013
ORF1ab/nsp2575E575KGaaAaa11B.1.177.100.000878
ORF1ab/nsp2575E575QGaaCaa11B.1.177.560.000668
ORF1ab/nsp2575E575KGaaAaa11B.1.177.600.000218
ORF1ab/nsp2575E575DgaAgaT11B.1.177.600.000218
ORF1ab/nsp2575E575delGAA---11B.1.177.830.001481
ORF1ab/nsp2575E575GgAagGa11B.1.20.000009
ORF1ab/nsp2575E575EgaAgaG11B.1.20.000009
ORF1ab/nsp2575E575KGaaAaa11B.1.2100.002132
ORF1ab/nsp2575E575KGaaAaa11B.1.2340.000132
ORF1ab/nsp2575E575EgaAgaG11B.1.2430.00007
ORF1ab/nsp2575E575AgAagCa11B.1.2480.029412
ORF1ab/nsp2575E575EgaAgaG11B.1.3510.00003
ORF1ab/nsp2575E575EgaAgaG11B.1.351.20.000303
ORF1ab/nsp2575E575KGaaAaa11B.1.360.000146
ORF1ab/nsp2575E575KGaaAaa11B.1.36.100.004785
ORF1ab/nsp2575E575KGaaAaa11B.1.36.170.000494
ORF1ab/nsp2575E575delGAA---11B.1.36.180.00042
ORF1ab/nsp2575E575DgaAgaC11B.1.36.220.001208
ORF1ab/nsp2575E575KGaaAaa11B.1.36.270.000763
ORF1ab/nsp2575E575delGAA---11B.1.36.380.001642
ORF1ab/nsp2575E575GgAagGa11B.1.3750.00082
ORF1ab/nsp2575E575AgAagCa11B.1.4520.013699
ORF1ab/nsp2575E575KGaaAaa11B.1.5200.021739
ORF1ab/nsp2575E575AgAagCa11B.1.5250.000113
ORF1ab/nsp2575E575delGAA---11B.1.5610.000397
ORF1ab/nsp2575E575XGaaTaa11B.1.5820.000491
ORF1ab/nsp2575E575KGaaAaa11B.1.5960.000087
ORF1ab/nsp2575E575XGaATaG11B.1.617.20.000004
ORF1ab/nsp2575E575delGAA---11B.1.617.20.000004
ORF1ab/nsp2575E575GgAagGa11B.1.617.20.000004
ORF1ab/nsp2575E575VgAagTa11B.1.617.20.000004
ORF1ab/nsp2575E575QGaaCaa11B.1.617.20.000004
ORF1ab/nsp2575E575delGAA---11B.1.617.30.002985
ORF1ab/nsp2575E575KGaaAaa11B.1.6190.000871
ORF1ab/nsp2575E575EgaAgaG11B.1.619.10.000641
ORF1ab/nsp2575E575delGAA---11B.1.6210.000089
ORF1ab/nsp2575E575KGaaAaa11B.1.9.50.005682
ORF1ab/nsp2575E575KGaaAaa11B.4.10.018868
ORF1ab/nsp2575E575delGAA---11B.570.015152
ORF1ab/nsp2575E575KGaaAaa11C.10.002392
ORF1ab/nsp2575E575DgaAgaT11P.10.000016
ORF1ab/nsp2575E575EgaAgaG11P.1.150.000232
ORF1ab/nsp2575E575KGaaAaa11P.1.150.000232
ORF1ab/nsp2575E575EgaAgaG11P.1.60.001946

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.