CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 467

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2467E467KE647KnonsynGaaAaa2052040.9951222204-2206
ORF1ab/nsp2467E467KE647KnonsynGaAAaG20510.004878052204-2206
ORF1ab/nsp2467E467GE647GnonsyngAagGa1281260.9843752204-2206
ORF1ab/nsp2467E467GE647GnonsyngAAgGT12810.00781252204-2206
ORF1ab/nsp2467E467GE647GnonsyngAAgGG12810.00781252204-2206
ORF1ab/nsp2467E467DE647DnonsyngaAgaC95770.8105262204-2206
ORF1ab/nsp2467E467DE647DnonsyngaAgaT95180.1894742204-2206
ORF1ab/nsp2467E467EE647EsyngaAgaG565612204-2206
ORF1ab/nsp2467E467delE647deldelGAA---424212204-2206
ORF1ab/nsp2467E467AE647AnonsyngAagCa353512204-2206
ORF1ab/nsp2467E467XE647XnonsynGaaTaa1290.752204-2206
ORF1ab/nsp2467E467XE647XnonsynGAaTGa1230.252204-2206
ORF1ab/nsp2467E467del1E647del1delgAag-a4412204-2206
ORF1ab/nsp2467E467RE647RnonsynGAaAGa430.752204-2206
ORF1ab/nsp2467E467RE647RnonsynGAAAGG410.252204-2206
ORF1ab/nsp2467E467QE647QnonsynGaaCaa2212204-2206
ORF1ab/nsp2467E467VE647VnonsyngAagTa2212204-2206
ORF1ab/nsp2467E467CE647CnonsynGAATGT1112204-2206
ORF1ab/nsp2467E467YE647YnonsynGaATaT1112204-2206
ORF1ab/nsp2467E467SE647SnonsynGAAAGT1112204-2206
ORF1ab/nsp2467E467NE647NnonsynGaAAaT1112204-2206
ORF1ab/nsp2467E467del2E647del2delgAAg--1112204-2206

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2467E467KGaaAaa204205All0.000039
ORF1ab/nsp2467E467KGaAAaG1205All0
ORF1ab/nsp2467E467GgAagGa126128All0.000024
ORF1ab/nsp2467E467GgAAgGT1128All0
ORF1ab/nsp2467E467GgAAgGG1128All0
ORF1ab/nsp2467E467KGaaAaa122122B.1.1.70.000109
ORF1ab/nsp2467E467DgaAgaC7795All0.000015
ORF1ab/nsp2467E467DgaAgaT1895All0.000003
ORF1ab/nsp2467E467EgaAgaG5656All0.000011
ORF1ab/nsp2467E467delGAA---4242All0.000008
ORF1ab/nsp2467E467AgAagCa3535All0.000007
ORF1ab/nsp2467E467GgAagGa1919B.10.000174
ORF1ab/nsp2467E467DgaAgaC1717AY.40.000026
ORF1ab/nsp2467E467DgaAgaC1616AY.1000.000736
ORF1ab/nsp2467E467GgAagGa1616B.1.1.70.000014
ORF1ab/nsp2467E467DgaAgaT1116B.1.1.70.00001
ORF1ab/nsp2467E467DgaAgaC516B.1.1.70.000004
ORF1ab/nsp2467E467KGaaAaa1616B.1.617.20.00006
ORF1ab/nsp2467E467EgaAgaG1515B.1.1.70.000013
ORF1ab/nsp2467E467GgAagGa1414AY.9.10.001172
ORF1ab/nsp2467E467AgAagCa1414B.1.1.70.000013
ORF1ab/nsp2467E467XGaaTaa912All0.000002
ORF1ab/nsp2467E467XGAaTGa312All0.000001
ORF1ab/nsp2467E467KGaaAaa1010AY.46.50.001984
ORF1ab/nsp2467E467DgaAgaC1010B.1.617.20.000038
ORF1ab/nsp2467E467GgAagGa99P.10.000142
ORF1ab/nsp2467E467delGAA---88B.1.1.70.000007
ORF1ab/nsp2467E467DgaAgaC88B.1.6141
ORF1ab/nsp2467E467GgAagGa77AY.390.000173
ORF1ab/nsp2467E467EgaAgaG77AY.40.000011
ORF1ab/nsp2467E467GgAagGa77B.1.1700.030172
ORF1ab/nsp2467E467KGaaAaa66AY.1030.000037
ORF1ab/nsp2467E467AgAagCa66AY.250.000036
ORF1ab/nsp2467E467KGaaAaa66AY.40.000009
ORF1ab/nsp2467E467DgaAgaC66AY.440.000037
ORF1ab/nsp2467E467delGAA---66B.10.000055
ORF1ab/nsp2467E467AgAagCa66B.1.3750.004918
ORF1ab/nsp2467E467GgAagGa66B.1.4270.000303
ORF1ab/nsp2467E467GgAagGa350.166667
ORF1ab/nsp2467E467GgAAgGG150.055556
ORF1ab/nsp2467E467GgAAgGT150.055556
ORF1ab/nsp2467E467KGaaAaa55B.10.000046
ORF1ab/nsp2467E467GgAagGa55B.1.2340.00066
ORF1ab/nsp2467E467KGaaAaa55B.1.5260.000118
ORF1ab/nsp2467E467KGaaAaa340.166667
ORF1ab/nsp2467E467RGAaAGa340.166667
ORF1ab/nsp2467E467XGAaTGa240.111111
ORF1ab/nsp2467E467XGaaTaa240.111111
ORF1ab/nsp2467E467KGaAAaG140.055556
ORF1ab/nsp2467E467RGAAAGG140.055556
ORF1ab/nsp2467E467del1gAag-a44All0.000001
ORF1ab/nsp2467E467RGAaAGa34All0.000001
ORF1ab/nsp2467E467RGAAAGG14All0
ORF1ab/nsp2467E467GgAagGa44B.1.177.520.00703
ORF1ab/nsp2467E467GgAagGa33AY.1030.000019
ORF1ab/nsp2467E467EgaAgaG33AY.1030.000019
ORF1ab/nsp2467E467EgaAgaG33AY.250.000018
ORF1ab/nsp2467E467KGaaAaa33AY.250.000018
ORF1ab/nsp2467E467DgaAgaC33AY.30.00003
ORF1ab/nsp2467E467EgaAgaG33AY.440.000018
ORF1ab/nsp2467E467DgaAgaC33AY.75.10.000541
ORF1ab/nsp2467E467GgAagGa33B.1.10.000054
ORF1ab/nsp2467E467KGaaAaa33B.1.10.000054
ORF1ab/nsp2467E467delGAA---33B.1.1.330.001263
ORF1ab/nsp2467E467EgaAgaG33B.1.36.290.001552
ORF1ab/nsp2467E467KGaaAaa33P.10.000047
ORF1ab/nsp2467E467VgAagTa22All0
ORF1ab/nsp2467E467QGaaCaa22All0
ORF1ab/nsp2467E467AgAagCa22AY.1030.000012
ORF1ab/nsp2467E467DgaAgaC22AY.250.000012
ORF1ab/nsp2467E467GgAagGa22AY.250.000012
ORF1ab/nsp2467E467EgaAgaG22AY.290.000032
ORF1ab/nsp2467E467EgaAgaG22AY.30.00002
ORF1ab/nsp2467E467KGaaAaa22AY.390.000049
ORF1ab/nsp2467E467delGAA---22AY.40.000003
ORF1ab/nsp2467E467GgAagGa22AY.40.000003
ORF1ab/nsp2467E467KGaaAaa22AY.4.2.10.000298
ORF1ab/nsp2467E467GgAagGa22AY.430.000009
ORF1ab/nsp2467E467KGaaAaa22AY.430.000009
ORF1ab/nsp2467E467AgAagCa22AY.440.000012
ORF1ab/nsp2467E467delGAA---22B.1.1.3480.001592
ORF1ab/nsp2467E467EgaAgaG22B.1.1.5190.000079
ORF1ab/nsp2467E467QGaaCaa22B.1.1.70.000002
ORF1ab/nsp2467E467DgaAgaC22B.1.1770.000026
ORF1ab/nsp2467E467GgAagGa22B.1.1770.000026
ORF1ab/nsp2467E467EgaAgaG22B.1.20.000018
ORF1ab/nsp2467E467GgAagGa22B.1.20.000018
ORF1ab/nsp2467E467GgAagGa22B.1.2210.000142
ORF1ab/nsp2467E467XGaaTaa12B.1.2210.000071
ORF1ab/nsp2467E467XGAaTGa12B.1.2210.000071
ORF1ab/nsp2467E467delGAA---22B.1.4240.016129
ORF1ab/nsp2467E467KGaaAaa22B.1.4270.000101
ORF1ab/nsp2467E467delGAA---22B.1.4290.000047
ORF1ab/nsp2467E467GgAagGa22B.1.5260.000047
ORF1ab/nsp2467E467GgAagGa22B.1.5410.00885
ORF1ab/nsp2467E467EgaAgaG22B.1.617.20.000008
ORF1ab/nsp2467E467delGAA---22B.1.617.20.000008
ORF1ab/nsp2467E467GgAagGa22B.1.617.20.000008
ORF1ab/nsp2467E467delGAA---22N.60.014184
ORF1ab/nsp2467E467delGAA---22P.20.000373
ORF1ab/nsp2467E467DgaAgaT110.055556
ORF1ab/nsp2467E467EgaAgaG110.055556
ORF1ab/nsp2467E467CGAATGT110.055556
ORF1ab/nsp2467E467YGaATaT110.055556
ORF1ab/nsp2467E467NGaAAaT110.055556
ORF1ab/nsp2467E467SGAAAGT110.055556
ORF1ab/nsp2467E467KGaaAaa11A0.000387
ORF1ab/nsp2467E467delGAA---11A0.000387
ORF1ab/nsp2467E467del2gAAg--11All0
ORF1ab/nsp2467E467SGAAAGT11All0
ORF1ab/nsp2467E467CGAATGT11All0
ORF1ab/nsp2467E467NGaAAaT11All0
ORF1ab/nsp2467E467YGaATaT11All0
ORF1ab/nsp2467E467EgaAgaG11AY.1080.001103
ORF1ab/nsp2467E467KGaaAaa11AY.1170.000085
ORF1ab/nsp2467E467DgaAgaC11AY.130.000161
ORF1ab/nsp2467E467del1gAag-a11AY.160.00038
ORF1ab/nsp2467E467GgAagGa11AY.230.00007
ORF1ab/nsp2467E467VgAagTa11AY.250.000006
ORF1ab/nsp2467E467KGaaAaa11AY.260.000028
ORF1ab/nsp2467E467GgAagGa11AY.30.00001
ORF1ab/nsp2467E467XGaaTaa11AY.30.00001
ORF1ab/nsp2467E467del1gAag-a11AY.30.00001
ORF1ab/nsp2467E467AgAagCa11AY.3.10.000085
ORF1ab/nsp2467E467DgaAgaT11AY.340.000097
ORF1ab/nsp2467E467DgaAgaC11AY.390.000025
ORF1ab/nsp2467E467KGaaAaa11AY.39.10.00004
ORF1ab/nsp2467E467XGaaTaa11AY.40.000002
ORF1ab/nsp2467E467AgAagCa11AY.40.000002
ORF1ab/nsp2467E467GgAagGa11AY.4.20.000022
ORF1ab/nsp2467E467EgaAgaG11AY.4.2.10.000149
ORF1ab/nsp2467E467EgaAgaG11AY.430.000004
ORF1ab/nsp2467E467delGAA---11AY.430.000004
ORF1ab/nsp2467E467KGaaAaa11AY.440.000006
ORF1ab/nsp2467E467DgaAgaT11AY.470.000031
ORF1ab/nsp2467E467GgAagGa11AY.50.000021
ORF1ab/nsp2467E467KGaaAaa11AY.5.40.000277
ORF1ab/nsp2467E467DgaAgaC11AY.520.000814
ORF1ab/nsp2467E467DgaAgaT11AY.60.000041
ORF1ab/nsp2467E467delGAA---11AY.60.000041
ORF1ab/nsp2467E467EgaAgaG11AY.740.000116
ORF1ab/nsp2467E467XGaaTaa11AY.750.000056
ORF1ab/nsp2467E467KGaaAaa11AY.850.000427
ORF1ab/nsp2467E467DgaAgaC11AY.940.000443
ORF1ab/nsp2467E467KGaaAaa11AY.98.10.000048
ORF1ab/nsp2467E467delGAA---11AY.990.001049
ORF1ab/nsp2467E467GgAagGa11B0.000128
ORF1ab/nsp2467E467EgaAgaG11B.10.000009
ORF1ab/nsp2467E467XGaaTaa11B.10.000009
ORF1ab/nsp2467E467AgAagCa11B.1.10.000018
ORF1ab/nsp2467E467del1gAag-a11B.1.10.000018
ORF1ab/nsp2467E467EgaAgaG11B.1.1.3510.002793
ORF1ab/nsp2467E467XGaaTaa11B.1.1.3760.005952
ORF1ab/nsp2467E467delGAA---11B.1.1.4160.000905
ORF1ab/nsp2467E467GgAagGa11B.1.1.630.000386
ORF1ab/nsp2467E467GgAagGa11B.1.110.30.000718
ORF1ab/nsp2467E467GgAagGa11B.1.1110.001175
ORF1ab/nsp2467E467AgAagCa11B.1.1660.008475
ORF1ab/nsp2467E467delGAA---11B.1.1790.003759
ORF1ab/nsp2467E467del2gAAg--11B.1.20.000009
ORF1ab/nsp2467E467DgaAgaT11B.1.20.000009
ORF1ab/nsp2467E467DgaAgaT11B.1.2340.000132
ORF1ab/nsp2467E467KGaaAaa11B.1.2430.00007
ORF1ab/nsp2467E467EgaAgaG11B.1.2430.00007
ORF1ab/nsp2467E467VgAagTa11B.1.258.110.000396
ORF1ab/nsp2467E467XGaaTaa11B.1.3510.00003
ORF1ab/nsp2467E467EgaAgaG11B.1.3510.00003
ORF1ab/nsp2467E467GgAagGa11B.1.36.290.000517
ORF1ab/nsp2467E467EgaAgaG11B.1.3690.000285
ORF1ab/nsp2467E467DgaAgaC11B.1.4290.000024
ORF1ab/nsp2467E467KGaaAaa11B.1.4290.000024
ORF1ab/nsp2467E467delGAA---11B.1.4340.052632
ORF1ab/nsp2467E467delGAA---11B.1.5610.000397
ORF1ab/nsp2467E467KGaaAaa11B.1.5800.004065
ORF1ab/nsp2467E467GgAagGa11B.1.6090.000479
ORF1ab/nsp2467E467AgAagCa11B.1.617.20.000004
ORF1ab/nsp2467E467del1gAag-a11B.1.6370.000073
ORF1ab/nsp2467E467KGaaAaa11B.4.50.011905
ORF1ab/nsp2467E467delGAA---11B.570.015152
ORF1ab/nsp2467E467GgAagGa11D.20.000075
ORF1ab/nsp2467E467DgaAgaT11P.10.000016
ORF1ab/nsp2467E467EgaAgaG11P.10.000016
ORF1ab/nsp2467E467delGAA---11P.10.000016
ORF1ab/nsp2467E467KGaaAaa11P.1.100.000269
ORF1ab/nsp2467E467EgaAgaG11P.1.140.000048
ORF1ab/nsp2467E467delGAA---11P.1.150.000232
ORF1ab/nsp2467E467GgAagGa11Q.70.001111
ORF1ab/nsp2467E467KGaaAaa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.