CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 456

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp2	456	K456R	K636R	nonsyn	aAg	aGg	496	496	1	2171-2173
ORF1ab/nsp2	456	K456K	K636K	syn	aaG	aaA	449	449	1	2171-2173
ORF1ab/nsp2	456	K456N	K636N	nonsyn	aaG	aaT	413	406	0.983051	2171-2173
ORF1ab/nsp2	456	K456N	K636N	nonsyn	aaG	aaC	413	7	0.0169492	2171-2173
ORF1ab/nsp2	456	K456T	K636T	nonsyn	aAg	aCg	86	86	1	2171-2173
ORF1ab/nsp2	456	K456E	K636E	nonsyn	Aag	Gag	85	85	1	2171-2173
ORF1ab/nsp2	456	K456del	K636del	del	AAG	---	49	49	1	2171-2173
ORF1ab/nsp2	456	K456X	K636X	nonsyn	Aag	Tag	10	8	0.8	2171-2173
ORF1ab/nsp2	456	K456X	K636X	nonsyn	AaG	TaA	10	2	0.2	2171-2173
ORF1ab/nsp2	456	K456M	K636M	nonsyn	aAg	aTg	6	6	1	2171-2173
ORF1ab/nsp2	456	K456del1	K636del1	del	aaG	aa-	3	2	0.666667	2171-2173
ORF1ab/nsp2	456	K456del1	K636del1	del	Aag	-ag	3	1	0.333333	2171-2173
ORF1ab/nsp2	456	K456Y	K636Y	nonsyn	AaG	TaT	1	1	1	2171-2173
ORF1ab/nsp2	456	K456L	K636L	nonsyn	AAg	TTg	1	1	1	2171-2173
ORF1ab/nsp2	456	K456Q	K636Q	nonsyn	Aag	Cag	1	1	1	2171-2173

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp2	456	K456R	aAg	aGg	496	496	All	0.000095
ORF1ab/nsp2	456	K456K	aaG	aaA	449	449	All	0.000086
ORF1ab/nsp2	456	K456N	aaG	aaT	406	413	All	0.000078
ORF1ab/nsp2	456	K456N	aaG	aaC	7	413	All	0.000001
ORF1ab/nsp2	456	K456N	aaG	aaT	149	149	AY.4	0.000232
ORF1ab/nsp2	456	K456R	aAg	aGg	116	116	B.1.1.7	0.000104
ORF1ab/nsp2	456	K456R	aAg	aGg	90	90	B.1.617.2	0.000339
ORF1ab/nsp2	456	K456T	aAg	aCg	86	86	All	0.000016
ORF1ab/nsp2	456	K456E	Aag	Gag	85	85	All	0.000016
ORF1ab/nsp2	456	K456K	aaG	aaA	83	83	B.1.1.7	0.000074
ORF1ab/nsp2	456	K456N	aaG	aaT	61	64	B.1.1.7	0.000055
ORF1ab/nsp2	456	K456N	aaG	aaC	3	64	B.1.1.7	0.000003
ORF1ab/nsp2	456	K456N	aaG	aaT	56	56	AY.4.2	0.001215
ORF1ab/nsp2	456	K456K	aaG	aaA	55	55	AY.36	0.008152
ORF1ab/nsp2	456	K456del	AAG	---	49	49	All	0.000009
ORF1ab/nsp2	456	K456T	aAg	aCg	40	40	AY.25	0.000241
ORF1ab/nsp2	456	K456R	aAg	aGg	40	40	AY.4.2	0.000868
ORF1ab/nsp2	456	K456R	aAg	aGg	36	36	AY.119	0.001271
ORF1ab/nsp2	456	K456K	aaG	aaA	36	36	C.36.1	0.149378
ORF1ab/nsp2	456	K456R	aAg	aGg	31	31	AY.102	0.000822
ORF1ab/nsp2	456	K456K	aaG	aaA	31	31	B.1.617.2	0.000117
ORF1ab/nsp2	456	K456E	Aag	Gag	25	25	B.1.1.7	0.000022
ORF1ab/nsp2	456	K456N	aaG	aaT	23	23	B.1.628	0.008104
ORF1ab/nsp2	456	K456K	aaG	aaA	22	22	AY.44	0.000134
ORF1ab/nsp2	456	K456R	aAg	aGg	20	20	AY.5	0.000413
ORF1ab/nsp2	456	K456N	aaG	aaT	20	20	B.1.617.2	0.000075
ORF1ab/nsp2	456	K456K	aaG	aaA	18	18	AY.9	0.001217
ORF1ab/nsp2	456	K456K	aaG	aaA	17	17	AY.119	0.0006
ORF1ab/nsp2	456	K456T	aAg	aCg	17	17	B.1.177	0.000224
ORF1ab/nsp2	456	K456T	aAg	aCg	15	15	B.1.177.12	0.002275
ORF1ab/nsp2	456	K456R	aAg	aGg	14	14	AY.4	0.000022
ORF1ab/nsp2	456	K456R	aAg	aGg	14	14	P.1	0.000221
ORF1ab/nsp2	456	K456K	aaG	aaA	12	12	AY.4	0.000019
ORF1ab/nsp2	456	K456R	aAg	aGg	12	12	B.1.438.4	0.255319
ORF1ab/nsp2	456	K456R	aAg	aGg	11	11	AY.59	0.005826
ORF1ab/nsp2	456	K456R	aAg	aGg	11	11	B.1.1	0.0002
ORF1ab/nsp2	456	K456E	Aag	Gag	11	11	B.1.2	0.000097
ORF1ab/nsp2	456	K456X	Aag	Tag	8	10	All	0.000002
ORF1ab/nsp2	456	K456X	AaG	TaA	2	10	All	0
ORF1ab/nsp2	456	K456N	aaG	aaT	10	10	AY.39.1	0.000396
ORF1ab/nsp2	456	K456K	aaG	aaA	10	10	B.1	0.000092
ORF1ab/nsp2	456	K456K	aaG	aaA	9	9	AY.103	0.000056
ORF1ab/nsp2	456	K456K	aaG	aaA	9	9	AY.43	0.00004
ORF1ab/nsp2	456	K456R	aAg	aGg	9	9	AY.58	0.008167
ORF1ab/nsp2	456	K456E	Aag	Gag	9	9	B.1.1.526	0.031915
ORF1ab/nsp2	456	K456R	aAg	aGg	9	9	B.1.351	0.000268
ORF1ab/nsp2	456	K456K	aaG	aaA	8	8	B.1.1.357	1
ORF1ab/nsp2	456	K456K	aaG	aaA	8	8	B.1.177	0.000105
ORF1ab/nsp2	456	K456K	aaG	aaA	8	8	B.1.351	0.000238
ORF1ab/nsp2	456	K456K	aaG	aaA	8	8	B.1.525	0.000905
ORF1ab/nsp2	456	K456K	aaG	aaA	8	8	P.1	0.000126
ORF1ab/nsp2	456	K456E	Aag	Gag	7	7	AY.25	0.000042
ORF1ab/nsp2	456	K456R	aAg	aGg	7	7	B.1.1.232	0.012704
ORF1ab/nsp2	456	K456del	AAG	---	7	7	B.1.1.7	0.000006
ORF1ab/nsp2	456	K456K	aaG	aaA	7	7	B.1.2	0.000062
ORF1ab/nsp2	456	K456R	aAg	aGg	7	7	C.37	0.000812
ORF1ab/nsp2	456	K456M	aAg	aTg	6	6	All	0.000001
ORF1ab/nsp2	456	K456K	aaG	aaA	6	6	AY.13	0.000966
ORF1ab/nsp2	456	K456N	aaG	aaT	6	6	AY.43	0.000027
ORF1ab/nsp2	456	K456N	aaG	aaC	3	6	AY.44	0.000018
ORF1ab/nsp2	456	K456N	aaG	aaT	3	6	AY.44	0.000018
ORF1ab/nsp2	456	K456N	aaG	aaT	6	6	B.1	0.000055
ORF1ab/nsp2	456	K456K	aaG	aaA	6	6	B.1.1.458	0.25
ORF1ab/nsp2	456	K456K	aaG	aaA	6	6	B.1.177.7	0.000989
ORF1ab/nsp2	456	K456N	aaG	aaT	5	5	AY.102	0.000133
ORF1ab/nsp2	456	K456N	aaG	aaT	5	5	AY.121	0.000677
ORF1ab/nsp2	456	K456K	aaG	aaA	5	5	AY.25	0.00003
ORF1ab/nsp2	456	K456T	aAg	aCg	5	5	AY.4	0.000008
ORF1ab/nsp2	456	K456E	Aag	Gag	5	5	AY.4	0.000008
ORF1ab/nsp2	456	K456E	Aag	Gag	5	5	AY.55	0.004587
ORF1ab/nsp2	456	K456del	AAG	---	5	5	B.1	0.000046
ORF1ab/nsp2	456	K456N	aaG	aaT	5	5	B.1.2	0.000044
ORF1ab/nsp2	456	K456R	aAg	aGg	5	5	B.1.2	0.000044
ORF1ab/nsp2	456	K456K	aaG	aaA	5	5	B.1.526	0.000118
ORF1ab/nsp2	456	K456N	aaG	aaT	5	5	P.1	0.000079
ORF1ab/nsp2	456	K456R	aAg	aGg	4	4	AY.25	0.000024
ORF1ab/nsp2	456	K456R	aAg	aGg	4	4	AY.43	0.000018
ORF1ab/nsp2	456	K456R	aAg	aGg	4	4	B.1	0.000037
ORF1ab/nsp2	456	K456X	Aag	Tag	3	4	B.1	0.000027
ORF1ab/nsp2	456	K456X	AaG	TaA	1	4	B.1	0.000009
ORF1ab/nsp2	456	K456K	aaG	aaA	4	4	B.1.241	0.003247
ORF1ab/nsp2	456	K456del	AAG	---	4	4	B.1.617.2	0.000015
ORF1ab/nsp2	456	K456T	aAg	aCg	4	4	B.1.617.2	0.000015
ORF1ab/nsp2	456	K456N	aaG	aaT	4	4	P.1.7	0.001277
ORF1ab/nsp2	456	K456del1	aaG	aa-	2	3	All	0
ORF1ab/nsp2	456	K456del1	Aag	-ag	1	3	All	0
ORF1ab/nsp2	456	K456K	aaG	aaA	3	3	AY.100	0.000138
ORF1ab/nsp2	456	K456N	aaG	aaT	3	3	AY.3	0.00003
ORF1ab/nsp2	456	K456N	aaG	aaT	3	3	AY.39	0.000074
ORF1ab/nsp2	456	K456N	aaG	aaT	3	3	AY.75.1	0.000541
ORF1ab/nsp2	456	K456T	aAg	aCg	3	3	B.1	0.000027
ORF1ab/nsp2	456	K456K	aaG	aaA	3	3	B.1.1	0.000054
ORF1ab/nsp2	456	K456del	AAG	---	3	3	B.1.1.33	0.001263
ORF1ab/nsp2	456	K456X	Aag	Tag	3	3	B.1.1.7	0.000003
ORF1ab/nsp2	456	K456N	aaG	aaT	2	3	B.1.525	0.000226
ORF1ab/nsp2	456	K456N	aaG	aaC	1	3	B.1.525	0.000113
ORF1ab/nsp2	456	K456K	aaG	aaA	3	3	B.1.596	0.000261
ORF1ab/nsp2	456	K456K	aaG	aaA	3	3	N.3	0.017442
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2		0.111111
ORF1ab/nsp2	456	K456X	AaG	TaA	1	2		0.055556
ORF1ab/nsp2	456	K456X	Aag	Tag	1	2		0.055556
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.103	0.000012
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	AY.103	0.000012
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.120.1	0.000642
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.29	0.000032
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.3	0.00002
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.39	0.000049
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.39.2	0.003082
ORF1ab/nsp2	456	K456del	AAG	---	2	2	AY.4	0.000003
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	AY.4.4	0.000818
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.4.4	0.000818
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	AY.42	0.00008
ORF1ab/nsp2	456	K456del	AAG	---	2	2	AY.43	0.000009
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.44	0.000012
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.46	0.000208
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.47	0.000062
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.5	0.000041
ORF1ab/nsp2	456	K456E	Aag	Gag	2	2	AY.53	0.000575
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	AY.6	0.000082
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	AY.61	0.00021
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.63	0.000774
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	AY.75	0.000112
ORF1ab/nsp2	456	K456M	aAg	aTg	2	2	AY.88	0.001768
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	AY.99	0.002099
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	B.1.1	0.000036
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.1.214	0.000111
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.1.312	0.003824
ORF1ab/nsp2	456	K456del	AAG	---	2	2	B.1.1.348	0.001592
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.1.398	0.006452
ORF1ab/nsp2	456	K456M	aAg	aTg	2	2	B.1.1.7	0.000002
ORF1ab/nsp2	456	K456E	Aag	Gag	2	2	B.1.177	0.000026
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	B.1.189	0.008584
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	B.1.234	0.000264
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.243	0.000139
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.404	0.002604
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	B.1.409	0.001563
ORF1ab/nsp2	456	K456del	AAG	---	2	2	B.1.424	0.016129
ORF1ab/nsp2	456	K456del	AAG	---	2	2	B.1.429	0.000047
ORF1ab/nsp2	456	K456N	aaG	aaT	2	2	B.1.429	0.000047
ORF1ab/nsp2	456	K456E	Aag	Gag	2	2	B.1.438.1	0.000215
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	B.1.466.2	0.000782
ORF1ab/nsp2	456	K456R	aAg	aGg	2	2	B.1.526	0.000047
ORF1ab/nsp2	456	K456E	Aag	Gag	2	2	B.1.617.2	0.000008
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	C.36	0.001821
ORF1ab/nsp2	456	K456del	AAG	---	2	2	N.6	0.014184
ORF1ab/nsp2	456	K456del	AAG	---	2	2	P.1	0.000032
ORF1ab/nsp2	456	K456K	aaG	aaA	2	2	P.1.15	0.000465
ORF1ab/nsp2	456	K456del	AAG	---	2	2	P.2	0.000373
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1		0.055556
ORF1ab/nsp2	456	K456del	AAG	---	1	1	A	0.000387
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	A.2.4	0.003367
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	A.6	0.005128
ORF1ab/nsp2	456	K456Q	Aag	Cag	1	1	All	0
ORF1ab/nsp2	456	K456L	AAg	TTg	1	1	All	0
ORF1ab/nsp2	456	K456Y	AaG	TaT	1	1	All	0
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.1	0.000396
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.10	0.00053
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.100	0.000046
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.102	0.000027
ORF1ab/nsp2	456	K456M	aAg	aTg	1	1	AY.103	0.000006
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.111	0.000183
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.113	0.000142
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.113	0.000142
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.117	0.000085
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	AY.117	0.000085
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.120	0.000037
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.120.2	0.001285
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.14	0.000088
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.16	0.00038
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.20	0.000039
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.20	0.000039
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.23	0.00007
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.26	0.000028
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	AY.26	0.000028
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.27	0.000065
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.28	0.00189
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.29	0.000016
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.29	0.000016
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	AY.36	0.000148
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.39	0.000025
ORF1ab/nsp2	456	K456M	aAg	aTg	1	1	AY.4	0.000002
ORF1ab/nsp2	456	K456X	Aag	Tag	1	1	AY.4	0.000002
ORF1ab/nsp2	456	K456L	AAg	TTg	1	1	AY.4	0.000002
ORF1ab/nsp2	456	K456del	AAG	---	1	1	AY.4.5	0.000107
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	AY.42	0.00004
ORF1ab/nsp2	456	K456T	aAg	aCg	1	1	AY.44	0.000006
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.45	0.000122
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.45	0.000122
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.46.2	0.000635
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.47	0.000031
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.54	0.000095
ORF1ab/nsp2	456	K456del	AAG	---	1	1	AY.54	0.000095
ORF1ab/nsp2	456	K456del	AAG	---	1	1	AY.6	0.000041
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.61	0.000105
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.70	0.000209
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.74	0.000116
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.75	0.000056
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.88	0.000884
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AY.93	0.000273
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	AY.95	0.000761
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.98	0.000079
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.99	0.001049
ORF1ab/nsp2	456	K456del	AAG	---	1	1	AY.99	0.001049
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	AY.99.2	0.000092
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	AZ.2	0.000821
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1	0.000009
ORF1ab/nsp2	456	K456Y	AaG	TaT	1	1	B.1	0.000009
ORF1ab/nsp2	456	K456del1	aaG	aa-	1	1	B.1.1	0.000018
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.1	0.000018
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.1.153	0.001095
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.1.225	0.007194
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.1.294	0.001266
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.1.307	0.002532
ORF1ab/nsp2	456	K456Q	Aag	Cag	1	1	B.1.1.311	0.000358
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.1.369	0.000446
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.1.372	0.000689
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.1.409	0.002833
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.1.416	0.000905
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.1.433	0.001425
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.1.434	0.000349
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.1.519	0.00004
ORF1ab/nsp2	456	K456del1	Aag	-ag	1	1	B.1.1.7	0.000001
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.110	0.004525
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.128	0.000635
ORF1ab/nsp2	456	K456T	aAg	aCg	1	1	B.1.160	0.000031
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.160	0.000031
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.177.12	0.000152
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.177.16	0.000664
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.177.17	0.000821
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.177.50	0.004695
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.177.7	0.000165
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.179	0.003759
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.2	0.000009
ORF1ab/nsp2	456	K456del1	aaG	aa-	1	1	B.1.2	0.000009
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.221	0.000071
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.222	0.001692
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.234	0.000132
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.240	0.000216
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.243	0.00007
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.349	0.000715
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.351	0.00003
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.356	0.001727
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.407	0.035714
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.411	0.003704
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.429	0.000024
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.459	0.004082
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.526	0.000024
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.549	0.007194
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.561	0.000397
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.561	0.000397
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.596	0.000087
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.609	0.000479
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	B.1.621	0.000089
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	B.1.621	0.000089
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.1.621	0.000089
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	B.1.621	0.000089
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.621.1	0.000506
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	B.1.637	0.000073
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.34	0.013699
ORF1ab/nsp2	456	K456del	AAG	---	1	1	B.57	0.015152
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	C.37.1	0.002618
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	D.2	0.000075
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	D.2	0.000075
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	P.1	0.000016
ORF1ab/nsp2	456	K456K	aaG	aaA	1	1	P.2	0.000187
ORF1ab/nsp2	456	K456E	Aag	Gag	1	1	Q.8	0.000165
ORF1ab/nsp2	456	K456R	aAg	aGg	1	1	Q.8	0.000165
ORF1ab/nsp2	456	K456N	aaG	aaT	1	1	Q.8	0.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.