CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 45

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp2	45	K45K	K225K	syn	aaG	aaA	782	782	1	938-940
ORF1ab/nsp2	45	K45R	K225R	nonsyn	aAg	aGg	546	545	0.998168	938-940
ORF1ab/nsp2	45	K45R	K225R	nonsyn	aAG	aGA	546	1	0.0018315	938-940
ORF1ab/nsp2	45	K45N	K225N	nonsyn	aaG	aaT	153	149	0.973856	938-940
ORF1ab/nsp2	45	K45N	K225N	nonsyn	aaG	aaC	153	4	0.0261438	938-940
ORF1ab/nsp2	45	K45T	K225T	nonsyn	aAg	aCg	42	42	1	938-940
ORF1ab/nsp2	45	K45del	K225del	del	AAG	---	35	35	1	938-940
ORF1ab/nsp2	45	K45E	K225E	nonsyn	Aag	Gag	35	34	0.971429	938-940
ORF1ab/nsp2	45	K45E	K225E	nonsyn	AaG	GaA	35	1	0.0285714	938-940
ORF1ab/nsp2	45	K45M	K225M	nonsyn	aAg	aTg	25	25	1	938-940
ORF1ab/nsp2	45	K45Q	K225Q	nonsyn	Aag	Cag	10	9	0.9	938-940
ORF1ab/nsp2	45	K45Q	K225Q	nonsyn	AaG	CaA	10	1	0.1	938-940
ORF1ab/nsp2	45	K45X	K225X	nonsyn	Aag	Tag	6	4	0.666667	938-940
ORF1ab/nsp2	45	K45X	K225X	nonsyn	AaG	TaA	6	2	0.333333	938-940
ORF1ab/nsp2	45	K45G	K225G	nonsyn	AAG	GGA	2	1	0.5	938-940
ORF1ab/nsp2	45	K45G	K225G	nonsyn	AAg	GGg	2	1	0.5	938-940
ORF1ab/nsp2	45	K45L	K225L	nonsyn	AAg	CTg	1	1	1	938-940
ORF1ab/nsp2	45	K45A	K225A	nonsyn	AAG	GCA	1	1	1	938-940

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp2	45	K45K	aaG	aaA	782	782	All	0.00015
ORF1ab/nsp2	45	K45R	aAg	aGg	545	546	All	0.000104
ORF1ab/nsp2	45	K45R	aAG	aGA	1	546	All	0
ORF1ab/nsp2	45	K45K	aaG	aaA	201	201	S.1	0.99505
ORF1ab/nsp2	45	K45R	aAg	aGg	190	190	B.1.1.7	0.00017
ORF1ab/nsp2	45	K45N	aaG	aaT	149	153	All	0.000028
ORF1ab/nsp2	45	K45N	aaG	aaC	4	153	All	0.000001
ORF1ab/nsp2	45	K45K	aaG	aaA	144	144	B.1.1.217	0.523636
ORF1ab/nsp2	45	K45K	aaG	aaA	103	103	B.1.1.348	0.082006
ORF1ab/nsp2	45	K45K	aaG	aaA	65	65	AY.92	0.018673
ORF1ab/nsp2	45	K45K	aaG	aaA	59	59	B.1.36.35	0.153646
ORF1ab/nsp2	45	K45N	aaG	aaT	56	56	AY.44	0.000341
ORF1ab/nsp2	45	K45R	aAg	aGg	52	52	AY.4	0.000081
ORF1ab/nsp2	45	K45T	aAg	aCg	42	42	All	0.000008
ORF1ab/nsp2	45	K45R	aAg	aGg	37	37	B.1.2	0.000326
ORF1ab/nsp2	45	K45del	AAG	---	35	35	All	0.000007
ORF1ab/nsp2	45	K45E	Aag	Gag	34	35	All	0.000007
ORF1ab/nsp2	45	K45E	AaG	GaA	1	35	All	0
ORF1ab/nsp2	45	K45N	aaG	aaT	28	28	B.1.1.7	0.000025
ORF1ab/nsp2	45	K45M	aAg	aTg	25	25	All	0.000005
ORF1ab/nsp2	45	K45R	aAg	aGg	25	25	AY.103	0.000155
ORF1ab/nsp2	45	K45R	aAg	aGg	21	21	B.1.596	0.00183
ORF1ab/nsp2	45	K45M	aAg	aTg	18	18	B.1.1.7	0.000016
ORF1ab/nsp2	45	K45R	aAg	aGg	17	17	B.1	0.000156
ORF1ab/nsp2	45	K45R	aAg	aGg	16	16	AY.4.2	0.000347
ORF1ab/nsp2	45	K45R	aAg	aGg	16	16	AY.43	0.000071
ORF1ab/nsp2	45	K45E	Aag	Gag	16	16	AY.98.1	0.000775
ORF1ab/nsp2	45	K45R	aAg	aGg	16	16	B.1.351	0.000476
ORF1ab/nsp2	45	K45R	aAg	aGg	16	16	B.1.617.2	0.00006
ORF1ab/nsp2	45	K45K	aaG	aaA	15	15	B.1	0.000137
ORF1ab/nsp2	45	K45K	aaG	aaA	14	14	B.1.396	0.00988
ORF1ab/nsp2	45	K45K	aaG	aaA	14	14	B.1.617.2	0.000053
ORF1ab/nsp2	45	K45K	aaG	aaA	13	13	AY.26	0.000368
ORF1ab/nsp2	45	K45T	aAg	aCg	11	11	AY.120.1	0.003531
ORF1ab/nsp2	45	K45K	aaG	aaA	11	11	AY.34	0.001067
ORF1ab/nsp2	45	K45K	aaG	aaA	11	11	B.1.1	0.0002
ORF1ab/nsp2	45	K45K	aaG	aaA	11	11	B.1.1.7	0.00001
ORF1ab/nsp2	45	K45Q	Aag	Cag	9	10	All	0.000002
ORF1ab/nsp2	45	K45Q	AaG	CaA	1	10	All	0
ORF1ab/nsp2	45	K45K	aaG	aaA	10	10	AY.4	0.000016
ORF1ab/nsp2	45	K45K	aaG	aaA	10	10	AY.43	0.000044
ORF1ab/nsp2	45	K45R	aAg	aGg	10	10	B.1.526	0.000235
ORF1ab/nsp2	45	K45N	aaG	aaT	9	10	B.1.617.2	0.000034
ORF1ab/nsp2	45	K45N	aaG	aaC	1	10	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45R	aAg	aGg	9	9	A.23.1	0.006338
ORF1ab/nsp2	45	K45R	aAg	aGg	9	9	B.1.1.141	0.018109
ORF1ab/nsp2	45	K45K	aaG	aaA	8	8	AY.102	0.000212
ORF1ab/nsp2	45	K45T	aAg	aCg	8	8	AY.4	0.000012
ORF1ab/nsp2	45	K45K	aaG	aaA	8	8	AY.44	0.000049
ORF1ab/nsp2	45	K45N	aaG	aaT	8	8	B.1.2	0.00007
ORF1ab/nsp2	45	K45K	aaG	aaA	7	7	AY.100	0.000322
ORF1ab/nsp2	45	K45R	aAg	aGg	7	7	AY.20	0.000272
ORF1ab/nsp2	45	K45N	aaG	aaT	7	7	AY.25	0.000042
ORF1ab/nsp2	45	K45R	aAg	aGg	7	7	B.1.221	0.000497
ORF1ab/nsp2	45	K45X	Aag	Tag	4	6	All	0.000001
ORF1ab/nsp2	45	K45X	AaG	TaA	2	6	All	0
ORF1ab/nsp2	45	K45K	aaG	aaA	6	6	AY.109	0.004438
ORF1ab/nsp2	45	K45K	aaG	aaA	6	6	P.1	0.000095
ORF1ab/nsp2	45	K45R	aAg	aGg	6	6	P.1	0.000095
ORF1ab/nsp2	45	K45R	aAg	aGg	5	5	AY.25	0.00003
ORF1ab/nsp2	45	K45Q	Aag	Cag	5	5	AY.25	0.00003
ORF1ab/nsp2	45	K45K	aaG	aaA	5	5	AY.3	0.00005
ORF1ab/nsp2	45	K45N	aaG	aaT	5	5	AY.4	0.000008
ORF1ab/nsp2	45	K45N	aaG	aaT	5	5	B.1	0.000046
ORF1ab/nsp2	45	K45R	aAg	aGg	5	5	B.1.1.220	0.009294
ORF1ab/nsp2	45	K45del	AAG	---	5	5	B.1.1.33	0.002104
ORF1ab/nsp2	45	K45T	aAg	aCg	5	5	B.1.1.7	0.000004
ORF1ab/nsp2	45	K45del	AAG	---	5	5	B.1.1.7	0.000004
ORF1ab/nsp2	45	K45X	Aag	Tag	2	4		0.111111
ORF1ab/nsp2	45	K45X	AaG	TaA	2	4		0.111111
ORF1ab/nsp2	45	K45T	aAg	aCg	4	4	AY.102	0.000106
ORF1ab/nsp2	45	K45T	aAg	aCg	4	4	B.1.1.176	0.001757
ORF1ab/nsp2	45	K45del	AAG	---	4	4	B.1.1.348	0.003185
ORF1ab/nsp2	45	K45K	aaG	aaA	4	4	B.1.1.519	0.000159
ORF1ab/nsp2	45	K45K	aaG	aaA	4	4	B.1.2	0.000035
ORF1ab/nsp2	45	K45N	aaG	aaT	4	4	B.1.466.2	0.001565
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3		0.166667
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	AY.20	0.000117
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	AY.33	0.0002
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	AY.5	0.000062
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	AY.99	0.003148
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	AY.99.2	0.000276
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	B.1.1.216	0.002671
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	B.1.1.269	0.00406
ORF1ab/nsp2	45	K45E	Aag	Gag	3	3	B.1.1.7	0.000003
ORF1ab/nsp2	45	K45N	aaG	aaT	3	3	B.1.177.55	0.006993
ORF1ab/nsp2	45	K45E	Aag	Gag	3	3	B.1.189	0.012876
ORF1ab/nsp2	45	K45T	aAg	aCg	3	3	B.1.2	0.000026
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	B.1.221	0.000213
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	B.1.324	0.004815
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	B.1.605	0.017857
ORF1ab/nsp2	45	K45K	aaG	aaA	3	3	B.1.637	0.000219
ORF1ab/nsp2	45	K45R	aAg	aGg	3	3	C.37	0.000348
ORF1ab/nsp2	45	K45Q	Aag	Cag	1	2		0.055556
ORF1ab/nsp2	45	K45Q	AaG	CaA	1	2		0.055556
ORF1ab/nsp2	45	K45E	Aag	Gag	1	2		0.055556
ORF1ab/nsp2	45	K45R	aAG	aGA	1	2		0.055556
ORF1ab/nsp2	45	K45R	aAg	aGg	1	2		0.055556
ORF1ab/nsp2	45	K45E	AaG	GaA	1	2		0.055556
ORF1ab/nsp2	45	K45G	AAg	GGg	1	2		0.055556
ORF1ab/nsp2	45	K45G	AAG	GGA	1	2		0.055556
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	A	0.000774
ORF1ab/nsp2	45	K45G	AAG	GGA	1	2	All	0
ORF1ab/nsp2	45	K45G	AAg	GGg	1	2	All	0
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	AY.102	0.000053
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.103	0.000012
ORF1ab/nsp2	45	K45M	aAg	aTg	2	2	AY.119	0.000071
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.119	0.000071
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.13	0.000322
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	AY.13	0.000322
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.25	0.000012
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	AY.3	0.00002
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	AY.35	0.000466
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.39	0.000049
ORF1ab/nsp2	45	K45N	aaG	aaT	2	2	AY.39	0.000049
ORF1ab/nsp2	45	K45E	Aag	Gag	2	2	AY.4	0.000003
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	AY.4.5	0.000215
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	AY.4.5	0.000215
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	B.1.1.222	0.000408
ORF1ab/nsp2	45	K45N	aaG	aaT	2	2	B.1.1.298	0.001724
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	B.1.1.318	0.000604
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	B.1.1.350	0.08
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	B.1.177	0.000026
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	B.1.177	0.000026
ORF1ab/nsp2	45	K45E	Aag	Gag	2	2	B.1.2	0.000018
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	B.1.36	0.000292
ORF1ab/nsp2	45	K45K	aaG	aaA	2	2	B.1.526	0.000047
ORF1ab/nsp2	45	K45M	aAg	aTg	2	2	B.1.617.2	0.000008
ORF1ab/nsp2	45	K45del	AAG	---	2	2	B.1.617.2	0.000008
ORF1ab/nsp2	45	K45N	aaG	aaT	2	2	D.2	0.00015
ORF1ab/nsp2	45	K45del	AAG	---	2	2	N.4	0.008511
ORF1ab/nsp2	45	K45del	AAG	---	2	2	N.6	0.014184
ORF1ab/nsp2	45	K45R	aAg	aGg	2	2	P.1.7	0.000639
ORF1ab/nsp2	45	K45del	AAG	---	2	2	P.2	0.000373
ORF1ab/nsp2	45	K45del	AAG	---	2	2	R.1	0.00018
ORF1ab/nsp2	45	K45del	AAG	---	1	1	A.2.2	0.001689
ORF1ab/nsp2	45	K45L	AAg	CTg	1	1	All	0
ORF1ab/nsp2	45	K45A	AAG	GCA	1	1	All	0
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.101	0.00049
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	AY.102	0.000027
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	AY.103	0.000006
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.106	0.000335
ORF1ab/nsp2	45	K45del	AAG	---	1	1	AY.111	0.000183
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	AY.116	0.000287
ORF1ab/nsp2	45	K45N	aaG	aaC	1	1	AY.117	0.000085
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.117	0.000085
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.119	0.000035
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.119	0.000035
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.120	0.000037
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.16	0.00038
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.16.1	0.00047
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.20	0.000039
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	AY.24	0.000431
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	AY.24	0.000431
ORF1ab/nsp2	45	K45del	AAG	---	1	1	AY.25	0.000006
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.26	0.000028
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.29	0.000016
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.29	0.000016
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	AY.29.1	0.000221
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.3	0.00001
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.3.1	0.000085
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.31	0.018519
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.36	0.000148
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	AY.36	0.000148
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.39	0.000025
ORF1ab/nsp2	45	K45del	AAG	---	1	1	AY.4	0.000002
ORF1ab/nsp2	45	K45M	aAg	aTg	1	1	AY.4	0.000002
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	AY.4.2	0.000022
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	AY.4.2	0.000022
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	AY.40	0.000964
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.43	0.000004
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	AY.44	0.000006
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.47	0.000031
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.5.4	0.000277
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.52	0.000814
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.54	0.000095
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	AY.65	0.000533
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	AY.65	0.000533
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.72	0.001361
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.74	0.000116
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.75	0.000056
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.9.1	0.000084
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	AY.99	0.001049
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	AY.99.2	0.000092
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B	0.000128
ORF1ab/nsp2	45	K45X	Aag	Tag	1	1	B.1	0.000009
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1	0.000009
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.1	0.000018
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.1	0.000018
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	B.1.1	0.000018
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.1.25	0.000569
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.1.25	0.000569
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.1.28	0.000311
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.1.28	0.000311
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.1.306	0.000438
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1.1.312	0.001912
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.1.365	0.005587
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1.1.420	0.001006
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.1.442	0.018519
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.1.519	0.00004
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.110.3	0.000718
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.160	0.000031
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	B.1.177	0.000013
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.177.16	0.000664
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.177.4	0.000211
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.177.4	0.000211
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.177.75	0.001041
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1.177.83	0.001481
ORF1ab/nsp2	45	K45Q	Aag	Cag	1	1	B.1.203	0.0625
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.234	0.000132
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.234	0.000132
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.237	0.004975
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.258	0.000067
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.260	0.003344
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.313	0.006579
ORF1ab/nsp2	45	K45N	aaG	aaC	1	1	B.1.351	0.00003
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.351	0.00003
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.36	0.000146
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.36.18	0.00042
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.391	0.001127
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.427	0.00005
ORF1ab/nsp2	45	K45X	Aag	Tag	1	1	B.1.427	0.00005
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.429	0.000024
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1.429	0.000024
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.438.1	0.000107
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.558	0.004566
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.576	0.000907
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.577	0.000687
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.582	0.000491
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	B.1.596	0.000087
ORF1ab/nsp2	45	K45Q	Aag	Cag	1	1	B.1.617.1	0.000129
ORF1ab/nsp2	45	K45L	AAg	CTg	1	1	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45E	Aag	Gag	1	1	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45Q	Aag	Cag	1	1	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45A	AAG	GCA	1	1	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45T	aAg	aCg	1	1	B.1.617.2	0.000004
ORF1ab/nsp2	45	K45del	AAG	---	1	1	B.1.617.3	0.002985
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.1.625	0.002353
ORF1ab/nsp2	45	K45K	aaG	aaA	1	1	B.1.628	0.000352
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	B.6.6	0.000889
ORF1ab/nsp2	45	K45del	AAG	---	1	1	C.35	0.000774
ORF1ab/nsp2	45	K45M	aAg	aTg	1	1	D.2	0.000075
ORF1ab/nsp2	45	K45N	aaG	aaC	1	1	P.1	0.000016
ORF1ab/nsp2	45	K45M	aAg	aTg	1	1	P.1	0.000016
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	P.2	0.000187
ORF1ab/nsp2	45	K45N	aaG	aaT	1	1	Q.1	0.000126
ORF1ab/nsp2	45	K45R	aAg	aGg	1	1	R.1	0.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.