CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 435 & Codon = aGc

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2435N435SN615SnonsynaAcaGc979712108-2110

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2435N435SaAcaGc9797All0.000019
ORF1ab/nsp2435N435SaAcaGc1818B.1.1.70.000016
ORF1ab/nsp2435N435SaAcaGc1313B.1.351.50.007794
ORF1ab/nsp2435N435SaAcaGc1010B.1.1.2910.007424
ORF1ab/nsp2435N435SaAcaGc77AY.40.000011
ORF1ab/nsp2435N435SaAcaGc55AY.430.000022
ORF1ab/nsp2435N435SaAcaGc44AY.1030.000025
ORF1ab/nsp2435N435SaAcaGc44B.1.617.20.000015
ORF1ab/nsp2435N435SaAcaGc33AY.470.000093
ORF1ab/nsp2435N435SaAcaGc33B.10.000027
ORF1ab/nsp2435N435SaAcaGc22AY.230.000139
ORF1ab/nsp2435N435SaAcaGc22AY.30.00002
ORF1ab/nsp2435N435SaAcaGc22AY.420.00008
ORF1ab/nsp2435N435SaAcaGc22B.1.20.000018
ORF1ab/nsp2435N435SaAcaGc22B.1.5960.000174
ORF1ab/nsp2435N435SaAcaGc11AY.1200.000037
ORF1ab/nsp2435N435SaAcaGc11AY.250.000006
ORF1ab/nsp2435N435SaAcaGc11AY.270.000065
ORF1ab/nsp2435N435SaAcaGc11AY.330.000067
ORF1ab/nsp2435N435SaAcaGc11AY.440.000006
ORF1ab/nsp2435N435SaAcaGc11AY.46.40.000165
ORF1ab/nsp2435N435SaAcaGc11AY.580.000907
ORF1ab/nsp2435N435SaAcaGc11AY.610.000105
ORF1ab/nsp2435N435SaAcaGc11AY.9.20.000037
ORF1ab/nsp2435N435SaAcaGc11B.1.1.1610.003534
ORF1ab/nsp2435N435SaAcaGc11B.1.1.3040.002809
ORF1ab/nsp2435N435SaAcaGc11B.1.1.3060.000438
ORF1ab/nsp2435N435SaAcaGc11B.1.2650.001271
ORF1ab/nsp2435N435SaAcaGc11B.1.5260.000024
ORF1ab/nsp2435N435SaAcaGc11B.3.10.001658
ORF1ab/nsp2435N435SaAcaGc11C.370.000116
ORF1ab/nsp2435N435SaAcaGc11D.20.000075
ORF1ab/nsp2435N435SaAcaGc11L.20.011364
ORF1ab/nsp2435N435SaAcaGc11P.10.000016
ORF1ab/nsp2435N435SaAcaGc11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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