CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 308 & Codon = gtA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2308V308VV488VsyngtGgtA36992368290.9955941727-1729

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2308V308VgtGgtA3682936992All0.007044
ORF1ab/nsp2308V308VgtGgtA2305223052AY.9.20.846691
ORF1ab/nsp2308V308VgtGgtA1182011820AY.9.10.989618
ORF1ab/nsp2308V308VgtGgtA506506AY.9.2.11
ORF1ab/nsp2308V308VgtGgtA276287AY.430.001223
ORF1ab/nsp2308V308VgtGgtA261274B.1.1.70.000234
ORF1ab/nsp2308V308VgtGgtA107110B.1.617.20.000403
ORF1ab/nsp2308V308VgtGgtA77100B.10.000705
ORF1ab/nsp2308V308VgtGgtA7083AY.250.000421
ORF1ab/nsp2308V308VgtGgtA5053AY.40.000078
ORF1ab/nsp2308V308VgtGgtA5353B.1.1770.000698
ORF1ab/nsp2308V308VgtGgtA3844AY.440.000231
ORF1ab/nsp2308V308VgtGgtA2727P.1.120.013069
ORF1ab/nsp2308V308VgtGgtA1924B.1.20.000167
ORF1ab/nsp2308V308VgtGgtA2323B.1.1.250.013076
ORF1ab/nsp2308V308VgtGgtA2323B.1.1.3160.021277
ORF1ab/nsp2308V308VgtGgtA2222AY.390.000544
ORF1ab/nsp2308V308VgtGgtA2020AY.750.00112
ORF1ab/nsp2308V308VgtGgtA1318P.10.000205
ORF1ab/nsp2308V308VgtGgtA1416AY.1030.000087
ORF1ab/nsp2308V308VgtGgtA1616AY.90.001082
ORF1ab/nsp2308V308VgtGgtA1415B.1.10.000254
ORF1ab/nsp2308V308VgtGgtA1111B.1.258.170.001144
ORF1ab/nsp2308V308VgtGgtA1010AY.4.20.000217
ORF1ab/nsp2308V308VgtGgtA1010AY.690.001867
ORF1ab/nsp2308V308VgtGgtA610B.1.1.5190.000238
ORF1ab/nsp2308V308VgtGgtA99AY.970.015306
ORF1ab/nsp2308V308VgtGgtA99B.1.2430.000626
ORF1ab/nsp2308V308VgtGgtA69B.1.4290.000141
ORF1ab/nsp2308V308VgtGgtA99Q.40.004093
ORF1ab/nsp2308V308VgtGgtA78AY.1020.000186
ORF1ab/nsp2308V308VgtGgtA88AY.1200.000297
ORF1ab/nsp2308V308VgtGgtA88AY.330.000534
ORF1ab/nsp2308V308VgtGgtA88AY.4.2.10.001192
ORF1ab/nsp2308V308VgtGgtA88B.1.6090.003835
ORF1ab/nsp2308V308VgtGgtA77AY.30.00007
ORF1ab/nsp2308V308VgtGgtA77AY.470.000218
ORF1ab/nsp2308V308VgtGgtA67AY.540.000572
ORF1ab/nsp2308V308VgtGgtA67B.1.2210.000426
ORF1ab/nsp2308V308VgtGgtA67C.370.000696
ORF1ab/nsp2308V308VgtGgtA160.055556
ORF1ab/nsp2308V308VgtGgtA66AY.16.10.00282
ORF1ab/nsp2308V308VgtGgtA66AY.260.00017
ORF1ab/nsp2308V308VgtGgtA56AY.50.000103
ORF1ab/nsp2308V308VgtGgtA66B.1.360.000875
ORF1ab/nsp2308V308VgtGgtA45AY.290.000063
ORF1ab/nsp2308V308VgtGgtA55AY.300.001979
ORF1ab/nsp2308V308VgtGgtA15AY.39.10.00004
ORF1ab/nsp2308V308VgtGgtA55AY.450.000608
ORF1ab/nsp2308V308VgtGgtA55AY.460.00052
ORF1ab/nsp2308V308VgtGgtA55AY.680.001369
ORF1ab/nsp2308V308VgtGgtA55AY.75.10.000902
ORF1ab/nsp2308V308VgtGgtA55B.1.3690.001426
ORF1ab/nsp2308V308VgtGgtA45B.1.5260.000094
ORF1ab/nsp2308V308VgtGgtA24AY.1170.000169
ORF1ab/nsp2308V308VgtGgtA24AY.1190.000071
ORF1ab/nsp2308V308VgtGgtA24AY.200.000078
ORF1ab/nsp2308V308VgtGgtA14AY.3.10.000085
ORF1ab/nsp2308V308VgtGgtA24B.1.1600.000062
ORF1ab/nsp2308V308VgtGgtA44B.1.6190.003484
ORF1ab/nsp2308V308VgtGgtA33AY.100.00159
ORF1ab/nsp2308V308VgtGgtA33AY.230.000209
ORF1ab/nsp2308V308VgtGgtA33AY.340.000291
ORF1ab/nsp2308V308VgtGgtA23AY.420.00008
ORF1ab/nsp2308V308VgtGgtA33AY.700.000626
ORF1ab/nsp2308V308VgtGgtA33AY.98.10.000145
ORF1ab/nsp2308V308VgtGgtA33B.1.1.1570.00274
ORF1ab/nsp2308V308VgtGgtA33B.1.1.1590.014019
ORF1ab/nsp2308V308VgtGgtA33B.1.1.2260.017442
ORF1ab/nsp2308V308VgtGgtA33B.1.1.3330.003229
ORF1ab/nsp2308V308VgtGgtA33B.1.3510.000089
ORF1ab/nsp2308V308VgtGgtA22A.10.000564
ORF1ab/nsp2308V308VgtGgtA22AY.1000.000092
ORF1ab/nsp2308V308VgtGgtA22AY.1180.000125
ORF1ab/nsp2308V308VgtGgtA22AY.320.001065
ORF1ab/nsp2308V308VgtGgtA12AY.4.40.000409
ORF1ab/nsp2308V308VgtGgtA22AY.610.00021
ORF1ab/nsp2308V308VgtGgtA22AY.650.001066
ORF1ab/nsp2308V308VgtGgtA22AY.710.00095
ORF1ab/nsp2308V308VgtGgtA22AY.930.000546
ORF1ab/nsp2308V308VgtGgtA22B.1.177.60.001953
ORF1ab/nsp2308V308VgtGgtA22B.1.177.630.005405
ORF1ab/nsp2308V308VgtGgtA22B.1.2580.000133
ORF1ab/nsp2308V308VgtGgtA22B.1.30.005236
ORF1ab/nsp2308V308VgtGgtA22B.1.350.016949
ORF1ab/nsp2308V308VgtGgtA22B.1.3750.001639
ORF1ab/nsp2308V308VgtGgtA22B.1.3990.003868
ORF1ab/nsp2308V308VgtGgtA22B.1.4270.000101
ORF1ab/nsp2308V308VgtGgtA12B.1.617.10.000129
ORF1ab/nsp2308V308VgtGgtA22B.1.9.50.011364
ORF1ab/nsp2308V308VgtGgtA12P.1.70.000319
ORF1ab/nsp2308V308VgtGgtA11AA.10.007246
ORF1ab/nsp2308V308VgtGgtA11AY.10.000396
ORF1ab/nsp2308V308VgtGgtA11AY.1100.000113
ORF1ab/nsp2308V308VgtGgtA11AY.1160.000287
ORF1ab/nsp2308V308VgtGgtA11AY.116.10.000311
ORF1ab/nsp2308V308VgtGgtA11AY.120.000316
ORF1ab/nsp2308V308VgtGgtA11AY.120.2.10.000498
ORF1ab/nsp2308V308VgtGgtA11AY.1210.000135
ORF1ab/nsp2308V308VgtGgtA11AY.130.000161
ORF1ab/nsp2308V308VgtGgtA11AY.140.000088
ORF1ab/nsp2308V308VgtGgtA11AY.150.002222
ORF1ab/nsp2308V308VgtGgtA11AY.4.50.000107
ORF1ab/nsp2308V308VgtGgtA11AY.46.10.001027
ORF1ab/nsp2308V308VgtGgtA11AY.520.000814
ORF1ab/nsp2308V308VgtGgtA11AY.550.000917
ORF1ab/nsp2308V308VgtGgtA11AY.590.00053
ORF1ab/nsp2308V308VgtGgtA11AY.7.10.000113
ORF1ab/nsp2308V308VgtGgtA11AY.840.000437
ORF1ab/nsp2308V308VgtGgtA11AY.960.002075
ORF1ab/nsp2308V308VgtGgtA11B.1.1.1640.005155
ORF1ab/nsp2308V308VgtGgtA11B.1.1.2070.001182
ORF1ab/nsp2308V308VgtGgtA11B.1.1.2160.00089
ORF1ab/nsp2308V308VgtGgtA11B.1.1.2200.001859
ORF1ab/nsp2308V308VgtGgtA11B.1.1.2220.000204
ORF1ab/nsp2308V308VgtGgtA11B.1.1.2570.009709
ORF1ab/nsp2308V308VgtGgtA11B.1.1.4640.001473
ORF1ab/nsp2308V308VgtGgtA11B.1.1.630.000386
ORF1ab/nsp2308V308VgtGgtA11B.1.177.820.000477
ORF1ab/nsp2308V308VgtGgtA11B.1.2130.014925
ORF1ab/nsp2308V308VgtGgtA11B.1.351.20.000303
ORF1ab/nsp2308V308VgtGgtA11B.1.3560.001727
ORF1ab/nsp2308V308VgtGgtA11B.1.36.290.000517
ORF1ab/nsp2308V308VgtGgtA11B.1.4040.001302
ORF1ab/nsp2308V308VgtGgtA11B.1.4480.002625
ORF1ab/nsp2308V308VgtGgtA11B.1.5090.000866
ORF1ab/nsp2308V308VgtGgtA11B.1.5730.006098
ORF1ab/nsp2308V308VgtGgtA11B.1.5820.000491
ORF1ab/nsp2308V308VgtGgtA11B.1.5950.000261
ORF1ab/nsp2308V308VgtGgtA11B.1.5960.000087
ORF1ab/nsp2308V308VgtGgtA11B.1.6370.000073
ORF1ab/nsp2308V308VgtGgtA11N.70.029412
ORF1ab/nsp2308V308VgtGgtA11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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