CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 186

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2186V186FV366FnonsynGttTtt36236211361-1363
ORF1ab/nsp2186V186VV366VsyngtTgtA2872070.7212541361-1363
ORF1ab/nsp2186V186VV366VsyngtTgtC287790.2752611361-1363
ORF1ab/nsp2186V186VV366VsyngtTgtG28710.003484321361-1363
ORF1ab/nsp2186V186IV366InonsynGttAtt26126111361-1363
ORF1ab/nsp2186V186AV366AnonsyngTtgCt535311361-1363
ORF1ab/nsp2186V186delV366deldelGTT---484811361-1363
ORF1ab/nsp2186V186LV366LnonsynGttCtt101011361-1363
ORF1ab/nsp2186V186del1V366del1delGtt-tt4411361-1363
ORF1ab/nsp2186V186del2V366del2delgTTg--3311361-1363
ORF1ab/nsp2186V186GV366GnonsyngTtgGt2211361-1363
ORF1ab/nsp2186V186RV366RnonsynGTtCGt2211361-1363
ORF1ab/nsp2186V186PV366PnonsynGTtCCt2211361-1363
ORF1ab/nsp2186V186CV366CnonsynGTtTGt1111361-1363
ORF1ab/nsp2186V186SV366SnonsynGTTAGC1111361-1363

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2186V186FGttTtt362362All0.000069
ORF1ab/nsp2186V186VgtTgtA207287All0.00004
ORF1ab/nsp2186V186VgtTgtC79287All0.000015
ORF1ab/nsp2186V186VgtTgtG1287All0
ORF1ab/nsp2186V186IGttAtt261261All0.00005
ORF1ab/nsp2186V186FGttTtt9191AY.40.000142
ORF1ab/nsp2186V186VgtTgtA6571B.1.1.70.000058
ORF1ab/nsp2186V186VgtTgtC671B.1.1.70.000005
ORF1ab/nsp2186V186FGttTtt5454B.1.1.70.000048
ORF1ab/nsp2186V186AgTtgCt5353All0.00001
ORF1ab/nsp2186V186delGTT---4848All0.000009
ORF1ab/nsp2186V186IGttAtt3434AY.1020.000901
ORF1ab/nsp2186V186IGttAtt3434B.1.617.20.000128
ORF1ab/nsp2186V186FGttTtt3131B.1.3960.021877
ORF1ab/nsp2186V186FGttTtt2828P.10.000441
ORF1ab/nsp2186V186VgtTgtA2225B.1.1770.00029
ORF1ab/nsp2186V186VgtTgtC325B.1.1770.00004
ORF1ab/nsp2186V186IGttAtt2424B.1.1.70.000021
ORF1ab/nsp2186V186VgtTgtC1921B.1.10.000345
ORF1ab/nsp2186V186VgtTgtA221B.1.10.000036
ORF1ab/nsp2186V186VgtTgtA1518AY.1030.000093
ORF1ab/nsp2186V186VgtTgtC318AY.1030.000019
ORF1ab/nsp2186V186FGttTtt1818AY.30.000179
ORF1ab/nsp2186V186FGttTtt1717AY.1030.000106
ORF1ab/nsp2186V186FGttTtt1717AY.440.000103
ORF1ab/nsp2186V186IGttAtt1515AY.30.000149
ORF1ab/nsp2186V186VgtTgtA1015AY.40.000016
ORF1ab/nsp2186V186VgtTgtC515AY.40.000008
ORF1ab/nsp2186V186VgtTgtA1315AY.430.000058
ORF1ab/nsp2186V186VgtTgtC215AY.430.000009
ORF1ab/nsp2186V186IGttAtt1414AY.250.000084
ORF1ab/nsp2186V186AgTtgCt1414B.1.1.70.000013
ORF1ab/nsp2186V186IGttAtt1414B.1.221.10.040698
ORF1ab/nsp2186V186FGttTtt1414C.180.036269
ORF1ab/nsp2186V186IGttAtt1414C.280.56
ORF1ab/nsp2186V186VgtTgtC1313B.1.20.000114
ORF1ab/nsp2186V186VgtTgtA1313B.1.2580.000865
ORF1ab/nsp2186V186VgtTgtA1212AY.290.000189
ORF1ab/nsp2186V186VgtTgtC612AY.30.00006
ORF1ab/nsp2186V186VgtTgtA612AY.30.00006
ORF1ab/nsp2186V186FGttTtt1212B.1.617.20.000045
ORF1ab/nsp2186V186FGttTtt1111AY.290.000174
ORF1ab/nsp2186V186IGttAtt1111AY.40.000017
ORF1ab/nsp2186V186LGttCtt1010All0.000002
ORF1ab/nsp2186V186FGttTtt1010B.10.000092
ORF1ab/nsp2186V186IGttAtt88AY.440.000049
ORF1ab/nsp2186V186delGTT---88B.1.1.70.000007
ORF1ab/nsp2186V186AgTtgCt77AY.40.000011
ORF1ab/nsp2186V186VgtTgtA77AY.920.002011
ORF1ab/nsp2186V186IGttAtt77B.1.10.000127
ORF1ab/nsp2186V186FGttTtt77R.10.00063
ORF1ab/nsp2186V186IGttAtt66B.1.1770.000079
ORF1ab/nsp2186V186VgtTgtA46B.1.617.20.000015
ORF1ab/nsp2186V186VgtTgtC16B.1.617.20.000004
ORF1ab/nsp2186V186VgtTgtG16B.1.617.20.000004
ORF1ab/nsp2186V186VgtTgtA55AY.1190.000177
ORF1ab/nsp2186V186IGttAtt55AY.1190.000177
ORF1ab/nsp2186V186VgtTgtA55AY.3.10.000426
ORF1ab/nsp2186V186AgTtgCt55AY.350.001165
ORF1ab/nsp2186V186IGttAtt55AY.390.000124
ORF1ab/nsp2186V186AgTtgCt55AY.4.50.000537
ORF1ab/nsp2186V186VgtTgtA55AY.440.00003
ORF1ab/nsp2186V186VgtTgtA55AY.750.00028
ORF1ab/nsp2186V186IGttAtt55AY.9.20.000184
ORF1ab/nsp2186V186delGTT---55B.1.1.330.002104
ORF1ab/nsp2186V186FGttTtt55D.20.000375
ORF1ab/nsp2186V186del1Gtt-tt44All0.000001
ORF1ab/nsp2186V186IGttAtt44AY.1200.000149
ORF1ab/nsp2186V186VgtTgtC44AY.46.40.000658
ORF1ab/nsp2186V186FGttTtt44B.1.10.000073
ORF1ab/nsp2186V186FGttTtt44B.1.20.000035
ORF1ab/nsp2186V186IGttAtt44B.1.20.000035
ORF1ab/nsp2186V186del2gTTg--33All0.000001
ORF1ab/nsp2186V186IGttAtt33AY.1030.000019
ORF1ab/nsp2186V186AgTtgCt33AY.4.20.000065
ORF1ab/nsp2186V186VgtTgtC33AY.4.20.000065
ORF1ab/nsp2186V186IGttAtt33AY.430.000013
ORF1ab/nsp2186V186VgtTgtC33AY.850.001282
ORF1ab/nsp2186V186VgtTgtC23AY.98.10.000097
ORF1ab/nsp2186V186VgtTgtA13AY.98.10.000048
ORF1ab/nsp2186V186VgtTgtA33B.10.000027
ORF1ab/nsp2186V186IGttAtt33B.10.000027
ORF1ab/nsp2186V186IGttAtt33B.1.1.1700.003741
ORF1ab/nsp2186V186delGTT---33B.1.1.3480.002389
ORF1ab/nsp2186V186IGttAtt33B.1.1.5190.000119
ORF1ab/nsp2186V186FGttTtt33B.1.36.220.003623
ORF1ab/nsp2186V186VgtTgtC33B.1.36.290.001552
ORF1ab/nsp2186V186delGTT---33B.1.617.20.000011
ORF1ab/nsp2186V186IGttAtt33B.1.6190.002613
ORF1ab/nsp2186V186IGttAtt33C.370.000348
ORF1ab/nsp2186V186IGttAtt33P.10.000047
ORF1ab/nsp2186V186PGTtCCt220.111111
ORF1ab/nsp2186V186LGttCtt220.111111
ORF1ab/nsp2186V186RGTtCGt220.111111
ORF1ab/nsp2186V186GgTtgGt22All0
ORF1ab/nsp2186V186RGTtCGt22All0
ORF1ab/nsp2186V186PGTtCCt22All0
ORF1ab/nsp2186V186FGttTtt22AY.250.000012
ORF1ab/nsp2186V186VgtTgtC12AY.250.000006
ORF1ab/nsp2186V186VgtTgtA12AY.250.000006
ORF1ab/nsp2186V186FGttTtt22AY.390.000049
ORF1ab/nsp2186V186VgtTgtA22AY.390.000049
ORF1ab/nsp2186V186IGttAtt22AY.450.000243
ORF1ab/nsp2186V186FGttTtt22AY.460.000208
ORF1ab/nsp2186V186VgtTgtA22AY.470.000062
ORF1ab/nsp2186V186IGttAtt22AY.470.000062
ORF1ab/nsp2186V186FGttTtt22AY.550.001835
ORF1ab/nsp2186V186IGttAtt22AY.740.000231
ORF1ab/nsp2186V186delGTT---22B.10.000018
ORF1ab/nsp2186V186FGttTtt22B.1.1.2140.000111
ORF1ab/nsp2186V186AgTtgCt22B.1.1.3260.003521
ORF1ab/nsp2186V186LGttCtt22B.1.1.70.000002
ORF1ab/nsp2186V186FGttTtt22B.1.1600.000062
ORF1ab/nsp2186V186IGttAtt22B.1.2340.000264
ORF1ab/nsp2186V186IGttAtt22B.1.3690.00057
ORF1ab/nsp2186V186FGttTtt22B.1.6210.000177
ORF1ab/nsp2186V186FGttTtt22C.160.002121
ORF1ab/nsp2186V186delGTT---22N.60.014184
ORF1ab/nsp2186V186VgtTgtA12P.10.000016
ORF1ab/nsp2186V186VgtTgtC12P.10.000016
ORF1ab/nsp2186V186delGTT---22P.20.000373
ORF1ab/nsp2186V186AgTtgCt11A.2.20.001689
ORF1ab/nsp2186V186AgTtgCt11A.23.10.000704
ORF1ab/nsp2186V186CGTtTGt11All0
ORF1ab/nsp2186V186SGTTAGC11All0
ORF1ab/nsp2186V186IGttAtt11AY.1000.000046
ORF1ab/nsp2186V186AgTtgCt11AY.1030.000006
ORF1ab/nsp2186V186VgtTgtA11AY.1110.000183
ORF1ab/nsp2186V186VgtTgtC11AY.1130.000142
ORF1ab/nsp2186V186AgTtgCt11AY.1130.000142
ORF1ab/nsp2186V186IGttAtt11AY.1130.000142
ORF1ab/nsp2186V186VgtTgtA11AY.1180.000063
ORF1ab/nsp2186V186SGTTAGC11AY.1190.000035
ORF1ab/nsp2186V186delGTT---11AY.1200.000037
ORF1ab/nsp2186V186CGTtTGt11AY.120.10.000321
ORF1ab/nsp2186V186VgtTgtA11AY.130.000161
ORF1ab/nsp2186V186FGttTtt11AY.140.000088
ORF1ab/nsp2186V186delGTT---11AY.190.00114
ORF1ab/nsp2186V186IGttAtt11AY.200.000039
ORF1ab/nsp2186V186FGttTtt11AY.200.000039
ORF1ab/nsp2186V186delGTT---11AY.260.000028
ORF1ab/nsp2186V186IGttAtt11AY.290.000016
ORF1ab/nsp2186V186delGTT---11AY.350.000233
ORF1ab/nsp2186V186IGttAtt11AY.360.000148
ORF1ab/nsp2186V186GgTtgGt11AY.40.000002
ORF1ab/nsp2186V186delGTT---11AY.40.000002
ORF1ab/nsp2186V186IGttAtt11AY.4.20.000022
ORF1ab/nsp2186V186IGttAtt11AY.420.00004
ORF1ab/nsp2186V186FGttTtt11AY.420.00004
ORF1ab/nsp2186V186FGttTtt11AY.430.000004
ORF1ab/nsp2186V186delGTT---11AY.430.000004
ORF1ab/nsp2186V186AgTtgCt11AY.440.000006
ORF1ab/nsp2186V186FGttTtt11AY.450.000122
ORF1ab/nsp2186V186delGTT---11AY.460.000104
ORF1ab/nsp2186V186IGttAtt11AY.530.000288
ORF1ab/nsp2186V186IGttAtt11AY.610.000105
ORF1ab/nsp2186V186AgTtgCt11AY.690.000187
ORF1ab/nsp2186V186IGttAtt11AY.690.000187
ORF1ab/nsp2186V186VgtTgtC11AY.7.10.000113
ORF1ab/nsp2186V186IGttAtt11AY.750.000056
ORF1ab/nsp2186V186delGTT---11AY.750.000056
ORF1ab/nsp2186V186delGTT---11AY.75.10.00018
ORF1ab/nsp2186V186IGttAtt11AY.90.000068
ORF1ab/nsp2186V186FGttTtt11AY.90.000068
ORF1ab/nsp2186V186AgTtgCt11AY.9.20.000037
ORF1ab/nsp2186V186FGttTtt11AY.98.10.000048
ORF1ab/nsp2186V186IGttAtt11AY.99.20.000092
ORF1ab/nsp2186V186FGttTtt11B0.000128
ORF1ab/nsp2186V186del2gTTg--11B0.000128
ORF1ab/nsp2186V186del1Gtt-tt11B.10.000009
ORF1ab/nsp2186V186delGTT---11B.1.10.000018
ORF1ab/nsp2186V186VgtTgtA11B.1.1.3060.000438
ORF1ab/nsp2186V186delGTT---11B.1.1.3150.008475
ORF1ab/nsp2186V186VgtTgtA11B.1.1.330.000421
ORF1ab/nsp2186V186delGTT---11B.1.1.3370.003597
ORF1ab/nsp2186V186FGttTtt11B.1.1.4090.002833
ORF1ab/nsp2186V186delGTT---11B.1.1.4480.002033
ORF1ab/nsp2186V186LGttCtt11B.1.1.460.004367
ORF1ab/nsp2186V186del1Gtt-tt11B.1.1.70.000001
ORF1ab/nsp2186V186del2gTTg--11B.1.1.70.000001
ORF1ab/nsp2186V186del1Gtt-tt11B.1.1040.00369
ORF1ab/nsp2186V186delGTT---11B.1.1400.018868
ORF1ab/nsp2186V186IGttAtt11B.1.1600.000031
ORF1ab/nsp2186V186delGTT---11B.1.177.510.004566
ORF1ab/nsp2186V186delGTT---11B.1.177.730.000566
ORF1ab/nsp2186V186FGttTtt11B.1.177.750.001041
ORF1ab/nsp2186V186FGttTtt11B.1.177.820.000477
ORF1ab/nsp2186V186del1Gtt-tt11B.1.20.000009
ORF1ab/nsp2186V186AgTtgCt11B.1.20.000009
ORF1ab/nsp2186V186AgTtgCt11B.1.2210.000071
ORF1ab/nsp2186V186FGttTtt11B.1.2210.000071
ORF1ab/nsp2186V186delGTT---11B.1.2420.018868
ORF1ab/nsp2186V186FGttTtt11B.1.2430.00007
ORF1ab/nsp2186V186delGTT---11B.1.2580.000067
ORF1ab/nsp2186V186FGttTtt11B.1.2580.000067
ORF1ab/nsp2186V186FGttTtt11B.1.2640.012346
ORF1ab/nsp2186V186AgTtgCt11B.1.2980.002114
ORF1ab/nsp2186V186IGttAtt11B.1.351.20.000303
ORF1ab/nsp2186V186IGttAtt11B.1.36.280.005747
ORF1ab/nsp2186V186IGttAtt11B.1.362.20.004717
ORF1ab/nsp2186V186IGttAtt11B.1.4090.000781
ORF1ab/nsp2186V186FGttTtt11B.1.4270.00005
ORF1ab/nsp2186V186VgtTgtA11B.1.4270.00005
ORF1ab/nsp2186V186delGTT---11B.1.4290.000024
ORF1ab/nsp2186V186IGttAtt11B.1.4290.000024
ORF1ab/nsp2186V186FGttTtt11B.1.4290.000024
ORF1ab/nsp2186V186AgTtgCt11B.1.4800.002488
ORF1ab/nsp2186V186AgTtgCt11B.1.5200.021739
ORF1ab/nsp2186V186delGTT---11B.1.5610.000397
ORF1ab/nsp2186V186LGttCtt11B.1.5710.009709
ORF1ab/nsp2186V186AgTtgCt11B.1.5760.000907
ORF1ab/nsp2186V186delGTT---11B.1.5960.000087
ORF1ab/nsp2186V186IGttAtt11B.1.5960.000087
ORF1ab/nsp2186V186VgtTgtA11B.1.6090.000479
ORF1ab/nsp2186V186FGttTtt11B.1.6120.002653
ORF1ab/nsp2186V186del2gTTg--11B.1.617.20.000004
ORF1ab/nsp2186V186AgTtgCt11B.1.617.20.000004
ORF1ab/nsp2186V186VgtTgtC11B.1.6210.000089
ORF1ab/nsp2186V186delGTT---11B.1.6210.000089
ORF1ab/nsp2186V186VgtTgtC11B.1.6370.000073
ORF1ab/nsp2186V186delGTT---11C.360.000911
ORF1ab/nsp2186V186AgTtgCt11C.370.000116
ORF1ab/nsp2186V186VgtTgtA11D.20.000075
ORF1ab/nsp2186V186GgTtgGt11D.20.000075
ORF1ab/nsp2186V186LGttCtt11P.10.000016
ORF1ab/nsp2186V186AgTtgCt11P.10.000016
ORF1ab/nsp2186V186LGttCtt11P.1.120.000484
ORF1ab/nsp2186V186FGttTtt11P.1.140.000048
ORF1ab/nsp2186V186IGttAtt11P.1.140.000048
ORF1ab/nsp2186V186AgTtgCt11P.1.150.000232
ORF1ab/nsp2186V186IGttAtt11P.1.150.000232
ORF1ab/nsp2186V186LGttCtt11P.1.170.000162
ORF1ab/nsp2186V186IGttAtt11P.1.70.000319
ORF1ab/nsp2186V186LGttCtt11P.20.000187
ORF1ab/nsp2186V186FGttTtt11Q.20.000613

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.