CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : CodonNum = 168

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2168N168SN348SnonsynaAtaGt1499149911307-1309
ORF1ab/nsp2168N168NN348NsynaaTaaC47147111307-1309
ORF1ab/nsp2168N168DN348DnonsynAatGat17517511307-1309
ORF1ab/nsp2168N168KN348KnonsynaaTaaG1441040.7222221307-1309
ORF1ab/nsp2168N168KN348KnonsynaaTaaA144400.2777781307-1309
ORF1ab/nsp2168N168TN348TnonsynaAtaCt454511307-1309
ORF1ab/nsp2168N168HN348HnonsynAatCat323211307-1309
ORF1ab/nsp2168N168delN348deldelAAT---232311307-1309
ORF1ab/nsp2168N168IN348InonsynaAtaTt16150.93751307-1309
ORF1ab/nsp2168N168IN348InonsynaATaTA1610.06251307-1309
ORF1ab/nsp2168N168del1N348del1delaaTaa-420.51307-1309
ORF1ab/nsp2168N168del1N348del1delAaTTa-410.251307-1309
ORF1ab/nsp2168N168del1N348del1delAAt-Gt410.251307-1309
ORF1ab/nsp2168N168YN348YnonsynAatTat2211307-1309
ORF1ab/nsp2168N168EN348EnonsynAaTGaA1111307-1309
ORF1ab/nsp2168N168del2N348del2delaATa--1111307-1309
ORF1ab/nsp2168N168QN348QnonsynAaTCaA1111307-1309
ORF1ab/nsp2168N168WN348WnonsynAATTGG1111307-1309

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2168N168SaAtaGt14991499All0.000287
ORF1ab/nsp2168N168SaAtaGt11491149AY.230.080142
ORF1ab/nsp2168N168NaaTaaC471471All0.00009
ORF1ab/nsp2168N168NaaTaaC181181AY.1030.001124
ORF1ab/nsp2168N168DAatGat175175All0.000033
ORF1ab/nsp2168N168KaaTaaG104144All0.00002
ORF1ab/nsp2168N168KaaTaaA40144All0.000008
ORF1ab/nsp2168N168KaaTaaG8489AY.40.000131
ORF1ab/nsp2168N168KaaTaaA589AY.40.000008
ORF1ab/nsp2168N168NaaTaaC6363B.1.1.70.000056
ORF1ab/nsp2168N168TaAtaCt4545All0.000009
ORF1ab/nsp2168N168DAatGat4545AY.30.000448
ORF1ab/nsp2168N168NaaTaaC4444B.1.177.50.054658
ORF1ab/nsp2168N168SaAtaGt3838B.1.1.70.000034
ORF1ab/nsp2168N168NaaTaaC3636B.1.617.20.000136
ORF1ab/nsp2168N168SaAtaGt3535AY.1020.000928
ORF1ab/nsp2168N168DAatGat3434AY.116.10.010589
ORF1ab/nsp2168N168HAatCat3232All0.000006
ORF1ab/nsp2168N168DAatGat3232AY.40.00005
ORF1ab/nsp2168N168SaAtaGt3030AY.630.011605
ORF1ab/nsp2168N168SaAtaGt3030B.1.617.20.000113
ORF1ab/nsp2168N168delAAT---2323All0.000004
ORF1ab/nsp2168N168NaaTaaC2121AY.40.000033
ORF1ab/nsp2168N168SaAtaGt2121AY.40.000033
ORF1ab/nsp2168N168SaAtaGt1919B.1.3510.000565
ORF1ab/nsp2168N168SaAtaGt1818AY.440.00011
ORF1ab/nsp2168N168IaAtaTt1516All0.000003
ORF1ab/nsp2168N168IaATaTA116All0
ORF1ab/nsp2168N168KaaTaaG1316B.1.1.70.000012
ORF1ab/nsp2168N168KaaTaaA316B.1.1.70.000003
ORF1ab/nsp2168N168NaaTaaC1515B.1.1.3410.882353
ORF1ab/nsp2168N168TaAtaCt1414B.1.1.70.000013
ORF1ab/nsp2168N168SaAtaGt1414Q.10.001769
ORF1ab/nsp2168N168DAatGat1313A.23.10.009155
ORF1ab/nsp2168N168SaAtaGt1313AY.470.000404
ORF1ab/nsp2168N168SaAtaGt1212AY.1160.003441
ORF1ab/nsp2168N168KaaTaaA1212B.1.1.2160.010686
ORF1ab/nsp2168N168NaaTaaC1212P.10.000189
ORF1ab/nsp2168N168DAatGat1111B.1.1.70.00001
ORF1ab/nsp2168N168SaAtaGt1010AY.430.000044
ORF1ab/nsp2168N168SaAtaGt99AY.240.003879
ORF1ab/nsp2168N168HAatCat99B.1.1.70.000008
ORF1ab/nsp2168N168NaaTaaC99B.1.1770.000119
ORF1ab/nsp2168N168TaAtaCt88AY.1180.000501
ORF1ab/nsp2168N168NaaTaaC88AY.120.10.002568
ORF1ab/nsp2168N168NaaTaaC88AY.440.000049
ORF1ab/nsp2168N168SaAtaGt77AY.390.000173
ORF1ab/nsp2168N168KaaTaaA47B.10.000037
ORF1ab/nsp2168N168KaaTaaG37B.10.000027
ORF1ab/nsp2168N168SaAtaGt66AY.30.00006
ORF1ab/nsp2168N168HAatCat66AY.360.000889
ORF1ab/nsp2168N168NaaTaaC66AY.420.000241
ORF1ab/nsp2168N168NaaTaaC66AY.430.000027
ORF1ab/nsp2168N168SaAtaGt66AY.610.000629
ORF1ab/nsp2168N168NaaTaaC66B.1.10.000109
ORF1ab/nsp2168N168DAatGat66L.30.021277
ORF1ab/nsp2168N168SaAtaGt55AY.1060.001674
ORF1ab/nsp2168N168SaAtaGt55AY.190.005701
ORF1ab/nsp2168N168TaAtaCt55AY.40.000008
ORF1ab/nsp2168N168DAatGat55B.10.000046
ORF1ab/nsp2168N168NaaTaaC55B.10.000046
ORF1ab/nsp2168N168KaaTaaA55B.1.10.000091
ORF1ab/nsp2168N168delAAT---55B.1.1.330.002104
ORF1ab/nsp2168N168DAatGat55B.1.1770.000066
ORF1ab/nsp2168N168del1aaTaa-24All0
ORF1ab/nsp2168N168del1AaTTa-14All0
ORF1ab/nsp2168N168del1AAt-Gt14All0
ORF1ab/nsp2168N168DAatGat44AY.250.000024
ORF1ab/nsp2168N168NaaTaaC44AY.250.000024
ORF1ab/nsp2168N168SaAtaGt44AY.360.000593
ORF1ab/nsp2168N168SaAtaGt44AY.460.000416
ORF1ab/nsp2168N168SaAtaGt44AY.60.000165
ORF1ab/nsp2168N168SaAtaGt33AY.1030.000019
ORF1ab/nsp2168N168TaAtaCt33AY.250.000018
ORF1ab/nsp2168N168NaaTaaC33AY.30.00003
ORF1ab/nsp2168N168DAatGat33AY.3.10.000256
ORF1ab/nsp2168N168SaAtaGt33AY.4.30.002525
ORF1ab/nsp2168N168IaAtaTt33AY.440.000018
ORF1ab/nsp2168N168DAatGat33AY.50.000062
ORF1ab/nsp2168N168HAatCat33AY.9.20.00011
ORF1ab/nsp2168N168SaAtaGt33B.10.000027
ORF1ab/nsp2168N168delAAT---33B.1.1.3480.002389
ORF1ab/nsp2168N168SaAtaGt33B.1.1.500.002037
ORF1ab/nsp2168N168delAAT---33B.1.1.70.000003
ORF1ab/nsp2168N168NaaTaaC33B.1.4290.000071
ORF1ab/nsp2168N168SaAtaGt33B.1.5260.000071
ORF1ab/nsp2168N168TaAtaCt33B.1.6090.001438
ORF1ab/nsp2168N168NaaTaaC33B.1.617.10.000387
ORF1ab/nsp2168N168DAatGat33B.1.617.20.000011
ORF1ab/nsp2168N168KaaTaaG23B.1.617.20.000008
ORF1ab/nsp2168N168KaaTaaA13B.1.617.20.000004
ORF1ab/nsp2168N168KaaTaaA220.111111
ORF1ab/nsp2168N168YAatTat22All0
ORF1ab/nsp2168N168NaaTaaC22AY.1020.000053
ORF1ab/nsp2168N168HAatCat22AY.1030.000012
ORF1ab/nsp2168N168KaaTaaA22AY.1030.000012
ORF1ab/nsp2168N168SaAtaGt22AY.250.000012
ORF1ab/nsp2168N168SaAtaGt22AY.330.000134
ORF1ab/nsp2168N168NaaTaaC22AY.390.000049
ORF1ab/nsp2168N168HAatCat22AY.40.000003
ORF1ab/nsp2168N168TaAtaCt22AY.440.000012
ORF1ab/nsp2168N168TaAtaCt22AY.450.000243
ORF1ab/nsp2168N168SaAtaGt22AY.450.000243
ORF1ab/nsp2168N168KaaTaaA12AY.50.000021
ORF1ab/nsp2168N168KaaTaaG12AY.50.000021
ORF1ab/nsp2168N168NaaTaaC22AY.650.001066
ORF1ab/nsp2168N168SaAtaGt22AY.750.000112
ORF1ab/nsp2168N168IaAtaTt22B.10.000018
ORF1ab/nsp2168N168NaaTaaC22B.1.1.3120.003824
ORF1ab/nsp2168N168NaaTaaC22B.1.1.3170.000823
ORF1ab/nsp2168N168YAatTat22B.1.1.70.000002
ORF1ab/nsp2168N168NaaTaaC22B.1.177.440.001038
ORF1ab/nsp2168N168NaaTaaC22B.1.20.000018
ORF1ab/nsp2168N168SaAtaGt22B.1.20.000018
ORF1ab/nsp2168N168DAatGat22B.1.4290.000047
ORF1ab/nsp2168N168NaaTaaC22B.1.5160.003914
ORF1ab/nsp2168N168SaAtaGt22B.1.5170.000854
ORF1ab/nsp2168N168NaaTaaC22B.1.5750.000607
ORF1ab/nsp2168N168IaAtaTt22B.1.617.20.000008
ORF1ab/nsp2168N168HAatCat22B.1.617.20.000008
ORF1ab/nsp2168N168NaaTaaC22B.1.6280.000705
ORF1ab/nsp2168N168delAAT---22N.60.014184
ORF1ab/nsp2168N168SaAtaGt22P.10.000032
ORF1ab/nsp2168N168DAatGat22P.10.000032
ORF1ab/nsp2168N168SaAtaGt22P.1.150.000465
ORF1ab/nsp2168N168delAAT---22P.20.000373
ORF1ab/nsp2168N168WAATTGG11All0
ORF1ab/nsp2168N168QAaTCaA11All0
ORF1ab/nsp2168N168del2aATa--11All0
ORF1ab/nsp2168N168EAaTGaA11All0
ORF1ab/nsp2168N168delAAT---11AY.1000.000046
ORF1ab/nsp2168N168TaAtaCt11AY.1020.000027
ORF1ab/nsp2168N168DAatGat11AY.1080.001103
ORF1ab/nsp2168N168SaAtaGt11AY.116.10.000311
ORF1ab/nsp2168N168HAatCat11AY.1170.000085
ORF1ab/nsp2168N168del1AAt-Gt11AY.1200.000037
ORF1ab/nsp2168N168delAAT---11AY.120.10.000321
ORF1ab/nsp2168N168NaaTaaC11AY.1210.000135
ORF1ab/nsp2168N168HAatCat11AY.16.10.00047
ORF1ab/nsp2168N168NaaTaaC11AY.20.000356
ORF1ab/nsp2168N168NaaTaaC11AY.200.000039
ORF1ab/nsp2168N168NaaTaaC11AY.230.00007
ORF1ab/nsp2168N168NaaTaaC11AY.270.000065
ORF1ab/nsp2168N168del2aATa--11AY.290.000016
ORF1ab/nsp2168N168NaaTaaC11AY.290.000016
ORF1ab/nsp2168N168IaAtaTt11AY.30.00001
ORF1ab/nsp2168N168TaAtaCt11AY.30.00001
ORF1ab/nsp2168N168HAatCat11AY.30.00001
ORF1ab/nsp2168N168SaAtaGt11AY.3.10.000085
ORF1ab/nsp2168N168DAatGat11AY.390.000025
ORF1ab/nsp2168N168del1aaTaa-11AY.39.10.00004
ORF1ab/nsp2168N168delAAT---11AY.40.000002
ORF1ab/nsp2168N168SaAtaGt11AY.4.20.000022
ORF1ab/nsp2168N168QAaTCaA11AY.400.000964
ORF1ab/nsp2168N168KaaTaaA11AY.430.000004
ORF1ab/nsp2168N168delAAT---11AY.430.000004
ORF1ab/nsp2168N168HAatCat11AY.440.000006
ORF1ab/nsp2168N168delAAT---11AY.440.000006
ORF1ab/nsp2168N168KaaTaaG11AY.440.000006
ORF1ab/nsp2168N168del1AaTTa-11AY.440.000006
ORF1ab/nsp2168N168NaaTaaC11AY.460.000104
ORF1ab/nsp2168N168SaAtaGt11AY.46.10.001027
ORF1ab/nsp2168N168SaAtaGt11AY.46.60.000072
ORF1ab/nsp2168N168NaaTaaC11AY.470.000031
ORF1ab/nsp2168N168SaAtaGt11AY.50.000021
ORF1ab/nsp2168N168SaAtaGt11AY.5.20.002463
ORF1ab/nsp2168N168TaAtaCt11AY.720.001361
ORF1ab/nsp2168N168delAAT---11AY.750.000056
ORF1ab/nsp2168N168TaAtaCt11AY.75.10.00018
ORF1ab/nsp2168N168DAatGat11AY.790.001211
ORF1ab/nsp2168N168IaATaTA11AY.850.000427
ORF1ab/nsp2168N168HAatCat11AY.910.00073
ORF1ab/nsp2168N168SaAtaGt11AY.920.000287
ORF1ab/nsp2168N168SaAtaGt11AY.940.000443
ORF1ab/nsp2168N168SaAtaGt11AY.980.000079
ORF1ab/nsp2168N168HAatCat11AY.980.000079
ORF1ab/nsp2168N168KaaTaaA11B0.000128
ORF1ab/nsp2168N168SaAtaGt11B0.000128
ORF1ab/nsp2168N168EAaTGaA11B.10.000009
ORF1ab/nsp2168N168DAatGat11B.1.10.000018
ORF1ab/nsp2168N168IaAtaTt11B.1.10.000018
ORF1ab/nsp2168N168SaAtaGt11B.1.10.000018
ORF1ab/nsp2168N168NaaTaaC11B.1.1.2650.003155
ORF1ab/nsp2168N168SaAtaGt11B.1.1.280.000311
ORF1ab/nsp2168N168TaAtaCt11B.1.1.280.000311
ORF1ab/nsp2168N168SaAtaGt11B.1.1.2840.000107
ORF1ab/nsp2168N168DAatGat11B.1.1.3170.000412
ORF1ab/nsp2168N168NaaTaaC11B.1.1.3180.000302
ORF1ab/nsp2168N168NaaTaaC11B.1.1.3290.003846
ORF1ab/nsp2168N168SaAtaGt11B.1.1.5190.00004
ORF1ab/nsp2168N168NaaTaaC11B.1.1.5190.00004
ORF1ab/nsp2168N168DAatGat11B.1.1.5190.00004
ORF1ab/nsp2168N168NaaTaaC11B.1.1.5220.017241
ORF1ab/nsp2168N168NaaTaaC11B.1.1.630.000386
ORF1ab/nsp2168N168WAATTGG11B.1.1.70.000001
ORF1ab/nsp2168N168IaAtaTt11B.1.1.70.000001
ORF1ab/nsp2168N168TaAtaCt11B.1.160.160.000929
ORF1ab/nsp2168N168SaAtaGt11B.1.1770.000013
ORF1ab/nsp2168N168SaAtaGt11B.1.177.100.000878
ORF1ab/nsp2168N168SaAtaGt11B.1.177.230.003236
ORF1ab/nsp2168N168KaaTaaA11B.1.177.40.000211
ORF1ab/nsp2168N168SaAtaGt11B.1.177.600.000218
ORF1ab/nsp2168N168IaAtaTt11B.1.20.000009
ORF1ab/nsp2168N168del1aaTaa-11B.1.20.000009
ORF1ab/nsp2168N168TaAtaCt11B.1.258.170.000104
ORF1ab/nsp2168N168SaAtaGt11B.1.3200.001245
ORF1ab/nsp2168N168DAatGat11B.1.3370.005587
ORF1ab/nsp2168N168SaAtaGt11B.1.351.20.000303
ORF1ab/nsp2168N168NaaTaaC11B.1.3690.000285
ORF1ab/nsp2168N168SaAtaGt11B.1.4270.00005
ORF1ab/nsp2168N168delAAT---11B.1.4290.000024
ORF1ab/nsp2168N168SaAtaGt11B.1.438.10.000107
ORF1ab/nsp2168N168SaAtaGt11B.1.466.20.000391
ORF1ab/nsp2168N168TaAtaCt11B.1.5260.000024
ORF1ab/nsp2168N168IaAtaTt11B.1.5650.00081
ORF1ab/nsp2168N168NaaTaaC11B.1.5960.000087
ORF1ab/nsp2168N168IaAtaTt11B.1.5960.000087
ORF1ab/nsp2168N168HAatCat11B.1.6060.006024
ORF1ab/nsp2168N168KaaTaaA11B.1.6090.000479
ORF1ab/nsp2168N168NaaTaaC11B.1.6210.000089
ORF1ab/nsp2168N168IaAtaTt11B.1.621.10.000506
ORF1ab/nsp2168N168SaAtaGt11B.1.6370.000073
ORF1ab/nsp2168N168SaAtaGt11B.4.10.018868
ORF1ab/nsp2168N168KaaTaaA11B.400.000364
ORF1ab/nsp2168N168delAAT---11C.360.000911
ORF1ab/nsp2168N168NaaTaaC11D.20.000075
ORF1ab/nsp2168N168IaAtaTt11D.20.000075
ORF1ab/nsp2168N168SaAtaGt11D.20.000075
ORF1ab/nsp2168N168HAatCat11P.10.000016
ORF1ab/nsp2168N168SaAtaGt11P.1.140.000048
ORF1ab/nsp2168N168SaAtaGt11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.