CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = T140R

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16140T140RT6938RnonsynaCaaGa84820.9761921076-21078
ORF1ab/nsp16140T140RT6938RnonsynaCAaGG8420.023809521076-21078

Details of the mutation T140R within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16140T140RaCaaGa8284All0.000016
ORF1ab/nsp16140T140RaCAaGG284All0
ORF1ab/nsp16140T140RaCaaGa5757B.1.1.70.000051
ORF1ab/nsp16140T140RaCaaGa99B.1.4290.000212
ORF1ab/nsp16140T140RaCAaGG240.111111
ORF1ab/nsp16140T140RaCaaGa240.111111
ORF1ab/nsp16140T140RaCaaGa22AY.30.00002
ORF1ab/nsp16140T140RaCaaGa22B.1.3110.000549
ORF1ab/nsp16140T140RaCaaGa22C.370.000232
ORF1ab/nsp16140T140RaCaaGa11AY.250.000006
ORF1ab/nsp16140T140RaCaaGa11AY.390.000025
ORF1ab/nsp16140T140RaCaaGa11AY.50.000021
ORF1ab/nsp16140T140RaCaaGa11B.1.1.3680.003086
ORF1ab/nsp16140T140RaCaaGa11B.1.1770.000013
ORF1ab/nsp16140T140RaCaaGa11B.1.2580.000067
ORF1ab/nsp16140T140RaCaaGa11B.1.3510.00003
ORF1ab/nsp16140T140RaCaaGa11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.