CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = T140I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16140T140IT6938InonsynaCaaTa14906149050.99993321076-21078
ORF1ab/nsp16140T140IT6938InonsynaCAaTC1490610.000067087121076-21078

Details of the mutation T140I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16140T140IaCaaTa1490514906All0.002851
ORF1ab/nsp16140T140IaCAaTC114906All0
ORF1ab/nsp16140T140IaCaaTa82948294B.1.1.70.007425
ORF1ab/nsp16140T140IaCaaTa10791079AY.360.159923
ORF1ab/nsp16140T140IaCaaTa578578B.1.1.700.197135
ORF1ab/nsp16140T140IaCaaTa418418B.1.1.5190.016599
ORF1ab/nsp16140T140IaCaaTa414414B.1.617.20.001559
ORF1ab/nsp16140T140IaCaaTa325325AY.40.000506
ORF1ab/nsp16140T140IaCaaTa292292B.1.20.002571
ORF1ab/nsp16140T140IaCaaTa252252P.10.00397
ORF1ab/nsp16140T140IaCaaTa140140AY.440.000852
ORF1ab/nsp16140T140IaCaaTa140140B.1.1770.001843
ORF1ab/nsp16140T140IaCaaTa130130AY.430.000576
ORF1ab/nsp16140T140IaCaaTa120120B.1.6210.010622
ORF1ab/nsp16140T140IaCaaTa117117AY.250.000704
ORF1ab/nsp16140T140IaCaaTa112112B.1.1600.003493
ORF1ab/nsp16140T140IaCaaTa101101AY.4.20.002191
ORF1ab/nsp16140T140IaCaaTa9192B.10.000834
ORF1ab/nsp16140T140IaCAaTC192B.10.000009
ORF1ab/nsp16140T140IaCaaTa9090AY.1020.002386
ORF1ab/nsp16140T140IaCaaTa8787AY.1030.00054
ORF1ab/nsp16140T140IaCaaTa8585B.1.4290.002
ORF1ab/nsp16140T140IaCaaTa8282AY.30.000816
ORF1ab/nsp16140T140IaCaaTa7676AY.260.002152
ORF1ab/nsp16140T140IaCaaTa7474B.1.3510.0022
ORF1ab/nsp16140T140IaCaaTa6868B.1.5260.001598
ORF1ab/nsp16140T140IaCaaTa6767AY.1210.009066
ORF1ab/nsp16140T140IaCaaTa6767C.370.007776
ORF1ab/nsp16140T140IaCaaTa6262P.1.140.002964
ORF1ab/nsp16140T140IaCaaTa5959B.1.10.00107
ORF1ab/nsp16140T140IaCaaTa5858AY.1000.002668
ORF1ab/nsp16140T140IaCaaTa5858Q.30.008412
ORF1ab/nsp16140T140IaCaaTa5151B.1.5250.005771
ORF1ab/nsp16140T140IaCaaTa4949AY.390.001211
ORF1ab/nsp16140T140IaCaaTa4848B.1.4270.002424
ORF1ab/nsp16140T140IaCaaTa4141B.1.6161
ORF1ab/nsp16140T140IaCaaTa4040B.1.1.1740.135135
ORF1ab/nsp16140T140IaCaaTa3838AY.1190.001342
ORF1ab/nsp16140T140IaCaaTa3434Q.10.004295
ORF1ab/nsp16140T140IaCaaTa3232AY.50.000661
ORF1ab/nsp16140T140IaCaaTa2828Q.80.004617
ORF1ab/nsp16140T140IaCaaTa2626P.1.120.012585
ORF1ab/nsp16140T140IaCaaTa2626P.1.150.006041
ORF1ab/nsp16140T140IaCaaTa2525AY.470.000778
ORF1ab/nsp16140T140IaCaaTa2424AY.610.002515
ORF1ab/nsp16140T140IaCaaTa2323B.1.2210.001634
ORF1ab/nsp16140T140IaCaaTa2222AY.330.001469
ORF1ab/nsp16140T140IaCaaTa2222B.1.1.390.011213
ORF1ab/nsp16140T140IaCaaTa2121B.1.6230.011266
ORF1ab/nsp16140T140IaCaaTa1919AY.750.001064
ORF1ab/nsp16140T140IaCaaTa1919B.1.5960.001656
ORF1ab/nsp16140T140IaCaaTa1717AY.1200.000632
ORF1ab/nsp16140T140IaCaaTa1717B.1.177.810.003218
ORF1ab/nsp16140T140IaCaaTa1616AY.4.50.00172
ORF1ab/nsp16140T140IaCaaTa1616AY.730.010645
ORF1ab/nsp16140T140IaCaaTa1515AY.98.10.000726
ORF1ab/nsp16140T140IaCaaTa1515B.1.1.2970.033557
ORF1ab/nsp16140T140IaCaaTa1414AY.290.000221
ORF1ab/nsp16140T140IaCaaTa1414AY.460.001457
ORF1ab/nsp16140T140IaCaaTa1313AY.230.000907
ORF1ab/nsp16140T140IaCaaTa1313AY.9.20.000477
ORF1ab/nsp16140T140IaCaaTa1313B.1.4990.013655
ORF1ab/nsp16140T140IaCaaTa1313P.20.002426
ORF1ab/nsp16140T140IaCaaTa1212AY.39.10.000475
ORF1ab/nsp16140T140IaCaaTa1212AY.60.000494
ORF1ab/nsp16140T140IaCaaTa1212B.1.2430.000835
ORF1ab/nsp16140T140IaCaaTa1212B.1.6370.000877
ORF1ab/nsp16140T140IaCaaTa1212P.1.70.003831
ORF1ab/nsp16140T140IaCaaTa1111AY.1170.00093
ORF1ab/nsp16140T140IaCaaTa1010AY.200.000389
ORF1ab/nsp16140T140IaCaaTa1010AY.380.004993
ORF1ab/nsp16140T140IaCaaTa1010AY.99.20.000922
ORF1ab/nsp16140T140IaCaaTa99AY.1180.000564
ORF1ab/nsp16140T140IaCaaTa99AY.370.002845
ORF1ab/nsp16140T140IaCaaTa99B.1.1.2840.000967
ORF1ab/nsp16140T140IaCaaTa99B.1.1.330.003788
ORF1ab/nsp16140T140IaCaaTa99B.1.3620.013867
ORF1ab/nsp16140T140IaCaaTa88AY.420.000322
ORF1ab/nsp16140T140IaCaaTa88AY.450.000973
ORF1ab/nsp16140T140IaCaaTa88B.1.617.10.001032
ORF1ab/nsp16140T140IaCaaTa88C.230.046512
ORF1ab/nsp16140T140IaCaaTa88P.1.170.001294
ORF1ab/nsp16140T140IaCaaTa77AY.680.001916
ORF1ab/nsp16140T140IaCaaTa77B.1.1.2140.000388
ORF1ab/nsp16140T140IaCaaTa77B.1.2580.000466
ORF1ab/nsp16140T140IaCaaTa77B.1.258.170.000728
ORF1ab/nsp16140T140IaCaaTa66AY.75.10.001082
ORF1ab/nsp16140T140IaCaaTa66B.1.177.210.000459
ORF1ab/nsp16140T140IaCaaTa66B.1.177.70.000989
ORF1ab/nsp16140T140IaCaaTa66B.1.466.20.002347
ORF1ab/nsp16140T140IaCaaTa66C.36.30.003403
ORF1ab/nsp16140T140IaCaaTa55AY.340.000485
ORF1ab/nsp16140T140IaCaaTa55AY.540.000477
ORF1ab/nsp16140T140IaCaaTa55AY.590.002648
ORF1ab/nsp16140T140IaCaaTa55AY.920.001436
ORF1ab/nsp16140T140IaCaaTa55B.1.1.2070.00591
ORF1ab/nsp16140T140IaCaaTa55B.1.1.280.001556
ORF1ab/nsp16140T140IaCaaTa55B.1.2180.025773
ORF1ab/nsp16140T140IaCaaTa55B.1.3240.008026
ORF1ab/nsp16140T140IaCaaTa55B.1.6200.00473
ORF1ab/nsp16140T140IaCaaTa44AY.1110.000733
ORF1ab/nsp16140T140IaCaaTa44AY.140.000352
ORF1ab/nsp16140T140IaCaaTa44AY.160.001519
ORF1ab/nsp16140T140IaCaaTa44AY.16.10.00188
ORF1ab/nsp16140T140IaCaaTa44AY.740.000463
ORF1ab/nsp16140T140IaCaaTa44B.1.1.630.001543
ORF1ab/nsp16140T140IaCaaTa44B.1.177.600.000874
ORF1ab/nsp16140T140IaCaaTa44B.1.2220.006768
ORF1ab/nsp16140T140IaCaaTa44B.1.3490.002859
ORF1ab/nsp16140T140IaCaaTa44B.1.36.310.007005
ORF1ab/nsp16140T140IaCaaTa44B.1.5610.001588
ORF1ab/nsp16140T140IaCaaTa44B.1.5950.001044
ORF1ab/nsp16140T140IaCaaTa44Q.40.001819
ORF1ab/nsp16140T140IaCaaTa44R.10.00036
ORF1ab/nsp16140T140IaCaaTa33A.2.50.001497
ORF1ab/nsp16140T140IaCaaTa33AE.80.001467
ORF1ab/nsp16140T140IaCaaTa33AU.30.006329
ORF1ab/nsp16140T140IaCaaTa33AY.1060.001005
ORF1ab/nsp16140T140IaCaaTa33AY.1140.000693
ORF1ab/nsp16140T140IaCaaTa33AY.270.000194
ORF1ab/nsp16140T140IaCaaTa33AY.46.40.000494
ORF1ab/nsp16140T140IaCaaTa33AY.480.001395
ORF1ab/nsp16140T140IaCaaTa33AY.5.30.001012
ORF1ab/nsp16140T140IaCaaTa33AY.5.40.00083
ORF1ab/nsp16140T140IaCaaTa33AY.530.000863
ORF1ab/nsp16140T140IaCaaTa33AY.650.001599
ORF1ab/nsp16140T140IaCaaTa33B.1.1.2220.000612
ORF1ab/nsp16140T140IaCaaTa33B.1.1.3180.000905
ORF1ab/nsp16140T140IaCaaTa33B.1.1.370.000579
ORF1ab/nsp16140T140IaCaaTa33B.1.1990.012397
ORF1ab/nsp16140T140IaCaaTa33B.1.2340.000396
ORF1ab/nsp16140T140IaCaaTa33B.1.36.290.001552
ORF1ab/nsp16140T140IaCaaTa33B.1.36.80.003
ORF1ab/nsp16140T140IaCaaTa33B.1.438.10.000322
ORF1ab/nsp16140T140IaCaaTa33B.1.564.10.004732
ORF1ab/nsp16140T140IaCaaTa33B.1.5750.00091
ORF1ab/nsp16140T140IaCaaTa33B.1.5990.010949
ORF1ab/nsp16140T140IaCaaTa33B.1.60.051724
ORF1ab/nsp16140T140IaCaaTa33B.1.6090.001438
ORF1ab/nsp16140T140IaCaaTa33B.60.00273
ORF1ab/nsp16140T140IaCaaTa22A.20.001324
ORF1ab/nsp16140T140IaCaaTa22A.2.5.30.020619
ORF1ab/nsp16140T140IaCaaTa22AD.20.000438
ORF1ab/nsp16140T140IaCaaTa22AP.10.003003
ORF1ab/nsp16140T140IaCaaTa22AY.1050.001286
ORF1ab/nsp16140T140IaCaaTa22AY.1160.000574
ORF1ab/nsp16140T140IaCaaTa22AY.120.000632
ORF1ab/nsp16140T140IaCaaTa22AY.130.000322
ORF1ab/nsp16140T140IaCaaTa22AY.29.10.000441
ORF1ab/nsp16140T140IaCaaTa22AY.34.10.00102
ORF1ab/nsp16140T140IaCaaTa22AY.400.001929
ORF1ab/nsp16140T140IaCaaTa22AY.46.60.000144
ORF1ab/nsp16140T140IaCaaTa22AY.520.001629
ORF1ab/nsp16140T140IaCaaTa22AY.550.001835
ORF1ab/nsp16140T140IaCaaTa22AY.620.000871
ORF1ab/nsp16140T140IaCaaTa22AY.670.000929
ORF1ab/nsp16140T140IaCaaTa22AY.770.002255
ORF1ab/nsp16140T140IaCaaTa22AY.780.003082
ORF1ab/nsp16140T140IaCaaTa22AY.80.001212
ORF1ab/nsp16140T140IaCaaTa22AY.850.000854
ORF1ab/nsp16140T140IaCaaTa22AY.870.001665
ORF1ab/nsp16140T140IaCaaTa22AY.90.000135
ORF1ab/nsp16140T140IaCaaTa22AY.900.001369
ORF1ab/nsp16140T140IaCaaTa22B0.000256
ORF1ab/nsp16140T140IaCaaTa22B.1.1.2200.003717
ORF1ab/nsp16140T140IaCaaTa22B.1.1.2910.001485
ORF1ab/nsp16140T140IaCaaTa22B.1.1.2940.002532
ORF1ab/nsp16140T140IaCaaTa22B.1.1.3110.000716
ORF1ab/nsp16140T140IaCaaTa22B.1.1.3170.000823
ORF1ab/nsp16140T140IaCaaTa22B.1.1.4320.002532
ORF1ab/nsp16140T140IaCaaTa22B.1.1.4340.000697
ORF1ab/nsp16140T140IaCaaTa22B.1.1.870.133333
ORF1ab/nsp16140T140IaCaaTa22B.1.177.150.001262
ORF1ab/nsp16140T140IaCaaTa22B.1.177.860.000367
ORF1ab/nsp16140T140IaCaaTa22B.1.177.870.001456
ORF1ab/nsp16140T140IaCaaTa22B.1.2360.004107
ORF1ab/nsp16140T140IaCaaTa22B.1.2650.002541
ORF1ab/nsp16140T140IaCaaTa22B.1.3200.002491
ORF1ab/nsp16140T140IaCaaTa22B.1.351.20.000605
ORF1ab/nsp16140T140IaCaaTa22B.1.3770.009132
ORF1ab/nsp16140T140IaCaaTa22B.1.4000.000858
ORF1ab/nsp16140T140IaCaaTa22B.1.4700.002809
ORF1ab/nsp16140T140IaCaaTa22B.1.5090.001732
ORF1ab/nsp16140T140IaCaaTa22B.1.6120.005305
ORF1ab/nsp16140T140IaCaaTa22B.4.70.020202
ORF1ab/nsp16140T140IaCaaTa22D.20.00015
ORF1ab/nsp16140T140IaCaaTa22N.30.011628
ORF1ab/nsp16140T140IaCaaTa22N.50.003534
ORF1ab/nsp16140T140IaCaaTa22P.1.130.001797
ORF1ab/nsp16140T140IaCaaTa22Q.20.001227
ORF1ab/nsp16140T140IaCaaTa11A0.000387
ORF1ab/nsp16140T140IaCaaTa11A.2.40.003367
ORF1ab/nsp16140T140IaCaaTa11AL.10.012987
ORF1ab/nsp16140T140IaCaaTa11AY.100.00053
ORF1ab/nsp16140T140IaCaaTa11AY.1100.000113
ORF1ab/nsp16140T140IaCaaTa11AY.116.10.000311
ORF1ab/nsp16140T140IaCaaTa11AY.20.000356
ORF1ab/nsp16140T140IaCaaTa11AY.23.10.000417
ORF1ab/nsp16140T140IaCaaTa11AY.240.000431
ORF1ab/nsp16140T140IaCaaTa11AY.300.000396
ORF1ab/nsp16140T140IaCaaTa11AY.4.10.000737
ORF1ab/nsp16140T140IaCaaTa11AY.4.30.000842
ORF1ab/nsp16140T140IaCaaTa11AY.510.000909
ORF1ab/nsp16140T140IaCaaTa11AY.690.000187
ORF1ab/nsp16140T140IaCaaTa11AY.7.10.000113
ORF1ab/nsp16140T140IaCaaTa11AY.820.001357
ORF1ab/nsp16140T140IaCaaTa11AY.830.001724
ORF1ab/nsp16140T140IaCaaTa11AY.840.000437
ORF1ab/nsp16140T140IaCaaTa11AY.860.00083
ORF1ab/nsp16140T140IaCaaTa11AY.910.00073
ORF1ab/nsp16140T140IaCaaTa11AY.930.000273
ORF1ab/nsp16140T140IaCaaTa11AY.980.000079
ORF1ab/nsp16140T140IaCaaTa11B.1.1.1330.008475
ORF1ab/nsp16140T140IaCaaTa11B.1.1.1760.000439
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2290.005747
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2310.003096
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2650.003155
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2790.001121
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2800.003086
ORF1ab/nsp16140T140IaCaaTa11B.1.1.2980.000862
ORF1ab/nsp16140T140IaCaaTa11B.1.1.3040.002809
ORF1ab/nsp16140T140IaCaaTa11B.1.1.3260.001761
ORF1ab/nsp16140T140IaCaaTa11B.1.1.3690.000446
ORF1ab/nsp16140T140IaCaaTa11B.1.1.4330.001425
ORF1ab/nsp16140T140IaCaaTa11B.1.1.4420.018519
ORF1ab/nsp16140T140IaCaaTa11B.1.1.5250.005464
ORF1ab/nsp16140T140IaCaaTa11B.1.1.540.003021
ORF1ab/nsp16140T140IaCaaTa11B.1.1.80.003584
ORF1ab/nsp16140T140IaCaaTa11B.1.160.200.008929
ORF1ab/nsp16140T140IaCaaTa11B.1.160.280.002924
ORF1ab/nsp16140T140IaCaaTa11B.1.177.120.000152
ORF1ab/nsp16140T140IaCaaTa11B.1.177.170.000821
ORF1ab/nsp16140T140IaCaaTa11B.1.177.350.000691
ORF1ab/nsp16140T140IaCaaTa11B.1.177.40.000211
ORF1ab/nsp16140T140IaCaaTa11B.1.177.510.004566
ORF1ab/nsp16140T140IaCaaTa11B.1.177.570.000281
ORF1ab/nsp16140T140IaCaaTa11B.1.177.770.000726
ORF1ab/nsp16140T140IaCaaTa11B.1.220.001318
ORF1ab/nsp16140T140IaCaaTa11B.1.2390.001221
ORF1ab/nsp16140T140IaCaaTa11B.1.243.10.022222
ORF1ab/nsp16140T140IaCaaTa11B.1.3110.000275
ORF1ab/nsp16140T140IaCaaTa11B.1.3130.006579
ORF1ab/nsp16140T140IaCaaTa11B.1.3460.001311
ORF1ab/nsp16140T140IaCaaTa11B.1.360.000146
ORF1ab/nsp16140T140IaCaaTa11B.1.36.180.00042
ORF1ab/nsp16140T140IaCaaTa11B.1.36.210.00216
ORF1ab/nsp16140T140IaCaaTa11B.1.3690.000285
ORF1ab/nsp16140T140IaCaaTa11B.1.4530.003236
ORF1ab/nsp16140T140IaCaaTa11B.1.4560.003268
ORF1ab/nsp16140T140IaCaaTa11B.1.4710.002732
ORF1ab/nsp16140T140IaCaaTa11B.1.4980.020408
ORF1ab/nsp16140T140IaCaaTa11B.1.5030.002488
ORF1ab/nsp16140T140IaCaaTa11B.1.5300.007143
ORF1ab/nsp16140T140IaCaaTa11B.1.5400.009709
ORF1ab/nsp16140T140IaCaaTa11B.1.5600.00463
ORF1ab/nsp16140T140IaCaaTa11B.1.5640.000426
ORF1ab/nsp16140T140IaCaaTa11B.1.5760.000907
ORF1ab/nsp16140T140IaCaaTa11B.1.5810.009434
ORF1ab/nsp16140T140IaCaaTa11B.1.5890.007576
ORF1ab/nsp16140T140IaCaaTa11B.1.6180.004032
ORF1ab/nsp16140T140IaCaaTa11B.1.6270.00202
ORF1ab/nsp16140T140IaCaaTa11B.1.6280.000352
ORF1ab/nsp16140T140IaCaaTa11B.1.930.000934
ORF1ab/nsp16140T140IaCaaTa11B.270.015385
ORF1ab/nsp16140T140IaCaaTa11B.30.000831
ORF1ab/nsp16140T140IaCaaTa11C.10.002392
ORF1ab/nsp16140T140IaCaaTa11C.270.018519
ORF1ab/nsp16140T140IaCaaTa11C.310.017857
ORF1ab/nsp16140T140IaCaaTa11C.360.000911
ORF1ab/nsp16140T140IaCaaTa11P.1.10.000318
ORF1ab/nsp16140T140IaCaaTa11P.1.160.000374
ORF1ab/nsp16140T140IaCaaTa11P.70.004367

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.