CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = R216H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16216R216HR7014HnonsyncGccAc316531270.98799421304-21306
ORF1ab/nsp16216R216HR7014HnonsyncGCcAT3165380.012006321304-21306

Details of the mutation R216H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16216R216HcGccAc31273165All0.000598
ORF1ab/nsp16216R216HcGCcAT383165All0.000007
ORF1ab/nsp16216R216HcGccAc605640AY.40.000942
ORF1ab/nsp16216R216HcGCcAT35640AY.40.000054
ORF1ab/nsp16216R216HcGccAc357357B.1.1.70.00032
ORF1ab/nsp16216R216HcGccAc297297P.60.933962
ORF1ab/nsp16216R216HcGccAc245245B.1.5670.816667
ORF1ab/nsp16216R216HcGccAc179180B.1.617.20.000674
ORF1ab/nsp16216R216HcGCcAT1180B.1.617.20.000004
ORF1ab/nsp16216R216HcGccAc155155B.1.1.2140.008596
ORF1ab/nsp16216R216HcGccAc153153B.1.4290.0036
ORF1ab/nsp16216R216HcGccAc9191AY.450.011073
ORF1ab/nsp16216R216HcGccAc8989R.10.008011
ORF1ab/nsp16216R216HcGccAc6868AY.3.10.005798
ORF1ab/nsp16216R216HcGccAc6464AY.50.001322
ORF1ab/nsp16216R216HcGccAc5959AY.1030.000366
ORF1ab/nsp16216R216HcGccAc5454AY.440.000329
ORF1ab/nsp16216R216HcGccAc4747B.10.00043
ORF1ab/nsp16216R216HcGccAc4545AY.290.00071
ORF1ab/nsp16216R216HcGccAc3737AY.46.30.034547
ORF1ab/nsp16216R216HcGccAc3535AY.30.000348
ORF1ab/nsp16216R216HcGccAc3535B.1.1770.000461
ORF1ab/nsp16216R216HcGccAc2929AY.46.60.002094
ORF1ab/nsp16216R216HcGccAc2222B.1.258.170.002287
ORF1ab/nsp16216R216HcGccAc2121AY.250.000126
ORF1ab/nsp16216R216HcGccAc1818AY.890.088235
ORF1ab/nsp16216R216HcGccAc1818B.1.1.280.005602
ORF1ab/nsp16216R216HcGccAc1717AY.430.000075
ORF1ab/nsp16216R216HcGccAc1414B.1.10.000254
ORF1ab/nsp16216R216HcGccAc1313B.1.3110.003569
ORF1ab/nsp16216R216HcGccAc1212P.10.000189
ORF1ab/nsp16216R216HcGccAc1111AY.4.20.000239
ORF1ab/nsp16216R216HcGccAc1111AY.750.000616
ORF1ab/nsp16216R216HcGccAc1010AY.98.10.000484
ORF1ab/nsp16216R216HcGccAc1010B.1.4090.007812
ORF1ab/nsp16216R216HcGccAc99B.1.4710.02459
ORF1ab/nsp16216R216HcGccAc88AY.330.000534
ORF1ab/nsp16216R216HcGccAc88AY.60.000329
ORF1ab/nsp16216R216HcGccAc88B.1.1.4170.021622
ORF1ab/nsp16216R216HcGccAc88B.1.6370.000585
ORF1ab/nsp16216R216HcGccAc77AY.1210.000947
ORF1ab/nsp16216R216HcGccAc77AY.200.000272
ORF1ab/nsp16216R216HcGccAc77B.1.1.500.004752
ORF1ab/nsp16216R216HcGccAc66AZ.20.004926
ORF1ab/nsp16216R216HcGccAc66B.1.1.2840.000644
ORF1ab/nsp16216R216HcGccAc66B.1.20.000053
ORF1ab/nsp16216R216HcGccAc56B.1.2580.000333
ORF1ab/nsp16216R216HcGCcAT16B.1.2580.000067
ORF1ab/nsp16216R216HcGccAc66B.1.3510.000178
ORF1ab/nsp16216R216HcGccAc66Q.80.000989
ORF1ab/nsp16216R216HcGccAc55AY.390.000124
ORF1ab/nsp16216R216HcGccAc55AY.470.000156
ORF1ab/nsp16216R216HcGccAc55B.1.1.1740.016892
ORF1ab/nsp16216R216HcGccAc55B.1.1.1890.007564
ORF1ab/nsp16216R216HcGccAc55B.1.3460.006553
ORF1ab/nsp16216R216HcGccAc55B.1.6210.000443
ORF1ab/nsp16216R216HcGccAc44B.1.1.3170.001647
ORF1ab/nsp16216R216HcGccAc44B.1.177.570.001124
ORF1ab/nsp16216R216HcGccAc44B.1.2430.000278
ORF1ab/nsp16216R216HcGccAc44B.1.4280.004082
ORF1ab/nsp16216R216HcGccAc33A.10.000846
ORF1ab/nsp16216R216HcGccAc33AY.1000.000138
ORF1ab/nsp16216R216HcGccAc33AY.1160.00086
ORF1ab/nsp16216R216HcGccAc33AY.230.000209
ORF1ab/nsp16216R216HcGccAc33AY.690.00056
ORF1ab/nsp16216R216HcGccAc33AY.880.002653
ORF1ab/nsp16216R216HcGccAc33B.1.1.2410.006211
ORF1ab/nsp16216R216HcGccAc33B.1.4270.000151
ORF1ab/nsp16216R216HcGccAc33B.1.5260.000071
ORF1ab/nsp16216R216HcGccAc33C.370.000348
ORF1ab/nsp16216R216HcGccAc33P.1.140.000143
ORF1ab/nsp16216R216HcGccAc33Q.20.00184
ORF1ab/nsp16216R216HcGccAc220.111111
ORF1ab/nsp16216R216HcGccAc22A.2.50.000998
ORF1ab/nsp16216R216HcGccAc22AY.1020.000053
ORF1ab/nsp16216R216HcGccAc22AY.1100.000225
ORF1ab/nsp16216R216HcGccAc22AY.1180.000125
ORF1ab/nsp16216R216HcGccAc22AY.1190.000071
ORF1ab/nsp16216R216HcGccAc22AY.1200.000074
ORF1ab/nsp16216R216HcGccAc22AY.260.000057
ORF1ab/nsp16216R216HcGccAc22AY.4.50.000215
ORF1ab/nsp16216R216HcGccAc22AY.410.000588
ORF1ab/nsp16216R216HcGccAc22AY.420.00008
ORF1ab/nsp16216R216HcGccAc22AY.460.000208
ORF1ab/nsp16216R216HcGccAc22AY.46.50.000397
ORF1ab/nsp16216R216HcGccAc22AY.930.000546
ORF1ab/nsp16216R216HcGccAc22B.1.1.3060.000877
ORF1ab/nsp16216R216HcGccAc22B.1.1.3180.000604
ORF1ab/nsp16216R216HcGccAc22B.1.177.120.000303
ORF1ab/nsp16216R216HcGccAc22B.1.2210.000142
ORF1ab/nsp16216R216HcGccAc22B.1.360.000292
ORF1ab/nsp16216R216HcGccAc22B.1.36.290.001035
ORF1ab/nsp16216R216HcGccAc22B.1.36.360.001204
ORF1ab/nsp16216R216HcGccAc22B.1.438.10.000215
ORF1ab/nsp16216R216HcGccAc22B.1.5250.000226
ORF1ab/nsp16216R216HcGccAc22B.1.5770.001375
ORF1ab/nsp16216R216HcGccAc22B.1.5960.000174
ORF1ab/nsp16216R216HcGccAc22B.460.041667
ORF1ab/nsp16216R216HcGccAc22P.1.60.003891
ORF1ab/nsp16216R216HcGccAc22P.1.70.000639
ORF1ab/nsp16216R216HcGccAc11A.2.5.20.001572
ORF1ab/nsp16216R216HcGccAc11AA.80.022222
ORF1ab/nsp16216R216HcGccAc11AU.30.00211
ORF1ab/nsp16216R216HcGccAc11AY.1010.00049
ORF1ab/nsp16216R216HcGccAc11AY.1110.000183
ORF1ab/nsp16216R216HcGccAc11AY.1140.000231
ORF1ab/nsp16216R216HcGccAc11AY.120.10.000321
ORF1ab/nsp16216R216HcGccAc11AY.160.00038
ORF1ab/nsp16216R216HcGccAc11AY.190.00114
ORF1ab/nsp16216R216HcGccAc11AY.240.000431
ORF1ab/nsp16216R216HcGccAc11AY.280.00189
ORF1ab/nsp16216R216HcGccAc11AY.370.000316
ORF1ab/nsp16216R216HcGccAc11AY.39.10.00004
ORF1ab/nsp16216R216HcGccAc11AY.46.40.000165
ORF1ab/nsp16216R216HcGccAc11AY.580.000907
ORF1ab/nsp16216R216HcGccAc11AY.610.000105
ORF1ab/nsp16216R216HcGccAc11AY.640.000595
ORF1ab/nsp16216R216HcGccAc11AY.710.000475
ORF1ab/nsp16216R216HcGccAc11AY.740.000116
ORF1ab/nsp16216R216HcGccAc11AY.790.001211
ORF1ab/nsp16216R216HcGccAc11AY.860.00083
ORF1ab/nsp16216R216HcGccAc11AY.90.000068
ORF1ab/nsp16216R216HcGccAc11AY.9.10.000084
ORF1ab/nsp16216R216HcGccAc11AY.910.00073
ORF1ab/nsp16216R216HcGccAc11AY.920.000287
ORF1ab/nsp16216R216HcGccAc11AY.980.000079
ORF1ab/nsp16216R216HcGccAc11B0.000128
ORF1ab/nsp16216R216HcGccAc11B.1.1.10.000327
ORF1ab/nsp16216R216HcGccAc11B.1.1.1110.014706
ORF1ab/nsp16216R216HcGccAc11B.1.1.1980.001468
ORF1ab/nsp16216R216HcGccAc11B.1.1.2220.000204
ORF1ab/nsp16216R216HcGccAc11B.1.1.2940.001266
ORF1ab/nsp16216R216HcGccAc11B.1.1.3260.001761
ORF1ab/nsp16216R216HcGccAc11B.1.1.3720.000689
ORF1ab/nsp16216R216HcGccAc11B.1.1.3840.02381
ORF1ab/nsp16216R216HcGccAc11B.1.1.390.00051
ORF1ab/nsp16216R216HcGccAc11B.1.1.4200.001006
ORF1ab/nsp16216R216HcGccAc11B.1.1.4320.001266
ORF1ab/nsp16216R216HcGCcAT11B.1.1.5190.00004
ORF1ab/nsp16216R216HcGccAc11B.1.1.700.000341
ORF1ab/nsp16216R216HcGccAc11B.1.1.740.00431
ORF1ab/nsp16216R216HcGccAc11B.1.1040.00369
ORF1ab/nsp16216R216HcGccAc11B.1.1600.000031
ORF1ab/nsp16216R216HcGccAc11B.1.177.160.000664
ORF1ab/nsp16216R216HcGccAc11B.1.177.190.001431
ORF1ab/nsp16216R216HcGccAc11B.1.177.20.004545
ORF1ab/nsp16216R216HcGccAc11B.1.177.600.000218
ORF1ab/nsp16216R216HcGccAc11B.1.177.70.000165
ORF1ab/nsp16216R216HcGccAc11B.1.177.730.000566
ORF1ab/nsp16216R216HcGccAc11B.1.177.820.000477
ORF1ab/nsp16216R216HcGccAc11B.1.177.860.000183
ORF1ab/nsp16216R216HcGccAc11B.1.2470.014925
ORF1ab/nsp16216R216HcGccAc11B.1.258.110.000396
ORF1ab/nsp16216R216HcGccAc11B.1.2790.000514
ORF1ab/nsp16216R216HcGccAc11B.1.3500.002933
ORF1ab/nsp16216R216HcGccAc11B.1.36.180.00042
ORF1ab/nsp16216R216HcGccAc11B.1.36.390.002217
ORF1ab/nsp16216R216HcGccAc11B.1.3690.000285
ORF1ab/nsp16216R216HcGccAc11B.1.3810.007812
ORF1ab/nsp16216R216HcGccAc11B.1.3970.004854
ORF1ab/nsp16216R216HcGccAc11B.1.5510.00129
ORF1ab/nsp16216R216HcGccAc11B.1.5640.000426
ORF1ab/nsp16216R216HcGccAc11B.1.5820.000491
ORF1ab/nsp16216R216HcGccAc11B.1.5880.00091
ORF1ab/nsp16216R216HcGccAc11B.1.5950.000261
ORF1ab/nsp16216R216HcGccAc11B.1.621.10.000506
ORF1ab/nsp16216R216HcGccAc11B.1.6230.000536
ORF1ab/nsp16216R216HcGccAc11B.1.80.001972
ORF1ab/nsp16216R216HcGccAc11B.6.60.000889
ORF1ab/nsp16216R216HcGccAc11C.36.30.000567
ORF1ab/nsp16216R216HcGccAc11P.1.17.10.000875
ORF1ab/nsp16216R216HcGccAc11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.