CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = P215L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16215P215LP7013LnonsyncCacTa14622146170.99965821301-21303
ORF1ab/nsp16215P215LP7013LnonsynCCaTTa1462240.0002735621301-21303
ORF1ab/nsp16215P215LP7013LnonsyncCAcTT1462210.000068390121301-21303

Details of the mutation P215L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16215P215LcCacTa1461714622All0.002796
ORF1ab/nsp16215P215LCCaTTa414622All0.000001
ORF1ab/nsp16215P215LcCAcTT114622All0
ORF1ab/nsp16215P215LcCacTa47054705B.1.1.70.004212
ORF1ab/nsp16215P215LcCacTa16711671AY.40.002601
ORF1ab/nsp16215P215LcCacTa15181518AY.3.10.129423
ORF1ab/nsp16215P215LcCacTa13851386AY.590.733581
ORF1ab/nsp16215P215LCCaTTa11386AY.590.00053
ORF1ab/nsp16215P215LcCacTa13521352B.1.20.011905
ORF1ab/nsp16215P215LcCacTa550550AY.1030.003415
ORF1ab/nsp16215P215LcCacTa270270B.1.617.20.001017
ORF1ab/nsp16215P215LcCacTa260260B.1.1.440.626506
ORF1ab/nsp16215P215LcCacTa220220AY.1050.141479
ORF1ab/nsp16215P215LcCacTa212212AY.440.00129
ORF1ab/nsp16215P215LcCacTa177177B.1.5260.00416
ORF1ab/nsp16215P215LcCacTa126126AY.250.000758
ORF1ab/nsp16215P215LcCacTa115115AY.260.003256
ORF1ab/nsp16215P215LcCacTa111111AY.30.001104
ORF1ab/nsp16215P215LcCacTa110110AY.430.000487
ORF1ab/nsp16215P215LcCacTa104104B.1.1770.001369
ORF1ab/nsp16215P215LcCacTa101101AY.890.495098
ORF1ab/nsp16215P215LcCacTa8181AY.200.003148
ORF1ab/nsp16215P215LcCacTa8181B.1.10.001469
ORF1ab/nsp16215P215LcCacTa7474Q.80.012203
ORF1ab/nsp16215P215LcCacTa6265B.1.5960.005403
ORF1ab/nsp16215P215LCCaTTa365B.1.5960.000261
ORF1ab/nsp16215P215LcCacTa6060AY.840.026247
ORF1ab/nsp16215P215LcCacTa4848AY.290.000757
ORF1ab/nsp16215P215LcCacTa4848AY.5.30.016194
ORF1ab/nsp16215P215LcCacTa4546B.10.000412
ORF1ab/nsp16215P215LcCAcTT146B.10.000009
ORF1ab/nsp16215P215LcCacTa4343B.1.3510.001278
ORF1ab/nsp16215P215LcCacTa4343B.1.5780.767857
ORF1ab/nsp16215P215LcCacTa4242AY.29.10.009261
ORF1ab/nsp16215P215LcCacTa4141P.10.000646
ORF1ab/nsp16215P215LcCacTa3939B.1.177.100.034241
ORF1ab/nsp16215P215LcCacTa3737B.1.4290.000871
ORF1ab/nsp16215P215LcCacTa3434AY.1100.003831
ORF1ab/nsp16215P215LcCacTa2929AY.390.000717
ORF1ab/nsp16215P215LcCacTa2626AY.1170.002197
ORF1ab/nsp16215P215LcCacTa2626AY.80.015758
ORF1ab/nsp16215P215LcCacTa2222AY.4.20.000477
ORF1ab/nsp16215P215LcCacTa2121AY.1180.001316
ORF1ab/nsp16215P215LcCacTa2121AY.50.000434
ORF1ab/nsp16215P215LcCacTa2020AY.39.10.000792
ORF1ab/nsp16215P215LcCacTa1818AY.1010.008828
ORF1ab/nsp16215P215LcCacTa1717AY.470.000529
ORF1ab/nsp16215P215LcCacTa1616B.1.6210.001416
ORF1ab/nsp16215P215LcCacTa1515AY.330.001002
ORF1ab/nsp16215P215LcCacTa1515B.1.1490.05137
ORF1ab/nsp16215P215LcCacTa1414AY.1000.000644
ORF1ab/nsp16215P215LcCacTa1414AY.750.000784
ORF1ab/nsp16215P215LcCacTa1414B.1.120.112
ORF1ab/nsp16215P215LcCacTa1313B.1.2430.000905
ORF1ab/nsp16215P215LcCacTa1212AY.1200.000446
ORF1ab/nsp16215P215LcCacTa1212AY.230.000837
ORF1ab/nsp16215P215LcCacTa1212AY.610.001257
ORF1ab/nsp16215P215LcCacTa1111B.1.1.2220.002244
ORF1ab/nsp16215P215LcCacTa1111P.1.140.000526
ORF1ab/nsp16215P215LcCacTa1010AY.1190.000353
ORF1ab/nsp16215P215LcCacTa1010AY.1210.001353
ORF1ab/nsp16215P215LcCacTa1010AY.9.10.000837
ORF1ab/nsp16215P215LcCacTa1010B.1.351.50.005995
ORF1ab/nsp16215P215LcCacTa99AY.116.10.002803
ORF1ab/nsp16215P215LcCacTa99AY.270.000582
ORF1ab/nsp16215P215LcCacTa99AY.980.000711
ORF1ab/nsp16215P215LcCacTa99B.1.2580.000599
ORF1ab/nsp16215P215LcCacTa99B.1.4080.03321
ORF1ab/nsp16215P215LcCacTa99B.1.617.10.001161
ORF1ab/nsp16215P215LcCacTa99C.80.040179
ORF1ab/nsp16215P215LcCacTa99Q.10.001137
ORF1ab/nsp16215P215LcCacTa99R.10.00081
ORF1ab/nsp16215P215LcCacTa88AY.1020.000212
ORF1ab/nsp16215P215LcCacTa88AY.550.007339
ORF1ab/nsp16215P215LcCacTa88AY.790.009685
ORF1ab/nsp16215P215LcCacTa88B.1.6370.000585
ORF1ab/nsp16215P215LcCacTa88C.36.30.004538
ORF1ab/nsp16215P215LcCacTa77AY.1160.002007
ORF1ab/nsp16215P215LcCacTa77B.1.1.4340.00244
ORF1ab/nsp16215P215LcCacTa77P.1.170.001132
ORF1ab/nsp16215P215LcCacTa77Q.20.004294
ORF1ab/nsp16215P215LcCacTa66AY.46.50.00119
ORF1ab/nsp16215P215LcCacTa66AY.98.10.000291
ORF1ab/nsp16215P215LcCacTa66B.1.177.210.000459
ORF1ab/nsp16215P215LcCacTa66B.1.466.20.002347
ORF1ab/nsp16215P215LcCacTa55AY.90.000338
ORF1ab/nsp16215P215LcCacTa55AY.9.20.000184
ORF1ab/nsp16215P215LcCacTa55B.1.177.280.037037
ORF1ab/nsp16215P215LcCacTa55B.1.177.800.00956
ORF1ab/nsp16215P215LcCacTa55Q.70.005556
ORF1ab/nsp16215P215LcCacTa44AU.20.009685
ORF1ab/nsp16215P215LcCacTa44AY.100.00212
ORF1ab/nsp16215P215LcCacTa44AY.1130.00057
ORF1ab/nsp16215P215LcCacTa44AY.300.001583
ORF1ab/nsp16215P215LcCacTa44AY.75.10.000721
ORF1ab/nsp16215P215LcCacTa44AY.950.003044
ORF1ab/nsp16215P215LcCacTa44B.1.1.3180.001207
ORF1ab/nsp16215P215LcCacTa44B.1.177.860.000734
ORF1ab/nsp16215P215LcCacTa44B.1.258.170.000416
ORF1ab/nsp16215P215LcCacTa44B.1.360.000584
ORF1ab/nsp16215P215LcCacTa44B.1.3810.03125
ORF1ab/nsp16215P215LcCacTa44B.1.5680.004444
ORF1ab/nsp16215P215LcCacTa44B.1.5950.001044
ORF1ab/nsp16215P215LcCacTa44C.380.032258
ORF1ab/nsp16215P215LcCacTa33AE.80.001467
ORF1ab/nsp16215P215LcCacTa33AY.130.000483
ORF1ab/nsp16215P215LcCacTa33AY.450.000365
ORF1ab/nsp16215P215LcCacTa33AY.460.000312
ORF1ab/nsp16215P215LcCacTa33AY.520.002443
ORF1ab/nsp16215P215LcCacTa33AY.530.000863
ORF1ab/nsp16215P215LcCacTa33AY.540.000286
ORF1ab/nsp16215P215LcCacTa33AY.850.001282
ORF1ab/nsp16215P215LcCacTa33B.1.1110.003525
ORF1ab/nsp16215P215LcCacTa33B.1.177.570.000843
ORF1ab/nsp16215P215LcCacTa33B.1.177.790.007026
ORF1ab/nsp16215P215LcCacTa33B.1.2210.000213
ORF1ab/nsp16215P215LcCacTa33B.1.3690.000856
ORF1ab/nsp16215P215LcCacTa33B.1.5250.000339
ORF1ab/nsp16215P215LcCacTa33B.1.5750.00091
ORF1ab/nsp16215P215LcCacTa33B.1.5770.002062
ORF1ab/nsp16215P215LcCacTa33D.20.000225
ORF1ab/nsp16215P215LcCacTa33P.1.150.000697
ORF1ab/nsp16215P215LcCacTa22AY.1060.00067
ORF1ab/nsp16215P215LcCacTa22AY.160.000759
ORF1ab/nsp16215P215LcCacTa22AY.360.000296
ORF1ab/nsp16215P215LcCacTa22AY.4.2.10.000298
ORF1ab/nsp16215P215LcCacTa22AY.400.001929
ORF1ab/nsp16215P215LcCacTa22AY.46.20.001271
ORF1ab/nsp16215P215LcCacTa22AY.46.60.000144
ORF1ab/nsp16215P215LcCacTa22AY.760.009662
ORF1ab/nsp16215P215LcCacTa22AY.930.000546
ORF1ab/nsp16215P215LcCacTa22AY.99.20.000184
ORF1ab/nsp16215P215LcCacTa22B.1.1.2690.002706
ORF1ab/nsp16215P215LcCacTa22B.1.1.2970.004474
ORF1ab/nsp16215P215LcCacTa22B.1.1.3060.000877
ORF1ab/nsp16215P215LcCacTa22B.1.1.3350.025974
ORF1ab/nsp16215P215LcCacTa22B.1.1.5190.000079
ORF1ab/nsp16215P215LcCacTa22B.1.177.830.002963
ORF1ab/nsp16215P215LcCacTa22B.1.2340.000264
ORF1ab/nsp16215P215LcCacTa22B.1.2410.001623
ORF1ab/nsp16215P215LcCacTa22B.1.258.240.021505
ORF1ab/nsp16215P215LcCacTa22B.1.2890.005319
ORF1ab/nsp16215P215LcCacTa22B.1.36.290.001035
ORF1ab/nsp16215P215LcCacTa22B.1.3990.003868
ORF1ab/nsp16215P215LcCacTa22B.1.4270.000101
ORF1ab/nsp16215P215LcCacTa22B.1.4970.00063
ORF1ab/nsp16215P215LcCacTa22B.1.5160.003914
ORF1ab/nsp16215P215LcCacTa22B.1.6160.04878
ORF1ab/nsp16215P215LcCacTa22B.1.621.10.001012
ORF1ab/nsp16215P215LcCacTa22C.20.032258
ORF1ab/nsp16215P215LcCacTa22N.50.003534
ORF1ab/nsp16215P215LcCacTa22P.20.000373
ORF1ab/nsp16215P215LcCacTa11A.2.50.000499
ORF1ab/nsp16215P215LcCacTa11A.210.00277
ORF1ab/nsp16215P215LcCacTa11AD.20.000219
ORF1ab/nsp16215P215LcCacTa11AY.1040.001984
ORF1ab/nsp16215P215LcCacTa11AY.1110.000183
ORF1ab/nsp16215P215LcCacTa11AY.1140.000231
ORF1ab/nsp16215P215LcCacTa11AY.1150.005208
ORF1ab/nsp16215P215LcCacTa11AY.140.000088
ORF1ab/nsp16215P215LcCacTa11AY.170.008197
ORF1ab/nsp16215P215LcCacTa11AY.350.000233
ORF1ab/nsp16215P215LcCacTa11AY.370.000316
ORF1ab/nsp16215P215LcCacTa11AY.380.000499
ORF1ab/nsp16215P215LcCacTa11AY.39.1.10.000725
ORF1ab/nsp16215P215LcCacTa11AY.4.40.000409
ORF1ab/nsp16215P215LcCacTa11AY.4.50.000107
ORF1ab/nsp16215P215LcCacTa11AY.46.40.000165
ORF1ab/nsp16215P215LcCacTa11AY.480.000465
ORF1ab/nsp16215P215LcCacTa11AY.5.40.000277
ORF1ab/nsp16215P215LcCacTa11AY.500.000799
ORF1ab/nsp16215P215LcCacTa11AY.580.000907
ORF1ab/nsp16215P215LcCacTa11AY.60.000041
ORF1ab/nsp16215P215LcCacTa11AY.620.000436
ORF1ab/nsp16215P215LcCacTa11AY.640.000595
ORF1ab/nsp16215P215LcCacTa11AY.740.000116
ORF1ab/nsp16215P215LcCacTa11AY.770.001127
ORF1ab/nsp16215P215LcCacTa11AY.870.000833
ORF1ab/nsp16215P215LcCacTa11AY.920.000287
ORF1ab/nsp16215P215LcCacTa11B0.000128
ORF1ab/nsp16215P215LcCacTa11B.1.1.10.000327
ORF1ab/nsp16215P215LcCacTa11B.1.1.1410.002012
ORF1ab/nsp16215P215LcCacTa11B.1.1.1570.000913
ORF1ab/nsp16215P215LcCacTa11B.1.1.1890.001513
ORF1ab/nsp16215P215LcCacTa11B.1.1.2140.000055
ORF1ab/nsp16215P215LcCacTa11B.1.1.2160.00089
ORF1ab/nsp16215P215LcCacTa11B.1.1.2200.001859
ORF1ab/nsp16215P215LcCacTa11B.1.1.2910.000742
ORF1ab/nsp16215P215LcCacTa11B.1.1.330.000421
ORF1ab/nsp16215P215LcCacTa11B.1.1.3330.001076
ORF1ab/nsp16215P215LcCacTa11B.1.1.4070.041667
ORF1ab/nsp16215P215LcCacTa11B.1.1.500.000679
ORF1ab/nsp16215P215LcCacTa11B.1.1.610.008772
ORF1ab/nsp16215P215LcCacTa11B.1.1.740.00431
ORF1ab/nsp16215P215LcCacTa11B.1.1030.019231
ORF1ab/nsp16215P215LcCacTa11B.1.1060.03125
ORF1ab/nsp16215P215LcCacTa11B.1.110.30.000718
ORF1ab/nsp16215P215LcCacTa11B.1.177.320.00135
ORF1ab/nsp16215P215LcCacTa11B.1.177.350.000691
ORF1ab/nsp16215P215LcCacTa11B.1.177.590.016129
ORF1ab/nsp16215P215LcCacTa11B.1.177.750.001041
ORF1ab/nsp16215P215LcCacTa11B.1.177.80.000752
ORF1ab/nsp16215P215LcCacTa11B.1.2400.000216
ORF1ab/nsp16215P215LcCacTa11B.1.2480.029412
ORF1ab/nsp16215P215LcCacTa11B.1.258.30.001675
ORF1ab/nsp16215P215LcCacTa11B.1.258.60.019608
ORF1ab/nsp16215P215LcCacTa11B.1.2930.0125
ORF1ab/nsp16215P215LcCacTa11B.1.3200.001245
ORF1ab/nsp16215P215LcCacTa11B.1.36.180.00042
ORF1ab/nsp16215P215LcCacTa11B.1.36.380.001642
ORF1ab/nsp16215P215LcCacTa11B.1.36.390.002217
ORF1ab/nsp16215P215LcCacTa11B.1.3670.000792
ORF1ab/nsp16215P215LcCacTa11B.1.3980.002976
ORF1ab/nsp16215P215LcCacTa11B.1.4280.00102
ORF1ab/nsp16215P215LcCacTa11B.1.438.10.000107
ORF1ab/nsp16215P215LcCacTa11B.1.4530.003236
ORF1ab/nsp16215P215LcCacTa11B.1.4690.00361
ORF1ab/nsp16215P215LcCacTa11B.1.4740.001901
ORF1ab/nsp16215P215LcCacTa11B.1.5170.000427
ORF1ab/nsp16215P215LcCacTa11B.1.5390.017544
ORF1ab/nsp16215P215LcCacTa11B.1.5410.004425
ORF1ab/nsp16215P215LcCacTa11B.1.5610.000397
ORF1ab/nsp16215P215LcCacTa11B.1.564.10.001577
ORF1ab/nsp16215P215LcCacTa11B.1.5880.00091
ORF1ab/nsp16215P215LcCacTa11B.1.5900.004545
ORF1ab/nsp16215P215LcCacTa11B.1.5970.00463
ORF1ab/nsp16215P215LcCacTa11B.1.6000.005848
ORF1ab/nsp16215P215LcCacTa11B.1.6230.000536
ORF1ab/nsp16215P215LcCacTa11B.1.6250.002353
ORF1ab/nsp16215P215LcCacTa11B.1.6320.006711
ORF1ab/nsp16215P215LcCacTa11B.1.910.002075
ORF1ab/nsp16215P215LcCacTa11B.1.930.000934
ORF1ab/nsp16215P215LcCacTa11D.50.004975
ORF1ab/nsp16215P215LcCacTa11P.1.10.000318
ORF1ab/nsp16215P215LcCacTa11P.1.100.000269
ORF1ab/nsp16215P215LcCacTa11Q.30.000145
ORF1ab/nsp16215P215LcCacTa11Q.50.016949

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.