CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = N143H

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16143N143HN6941HnonsynAaTCaC3033020.996721085-21087
ORF1ab/nsp16143N143HN6941HnonsynAatCat30310.0033003321085-21087

Details of the mutation N143H within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16143N143HAaTCaC302303All0.000058
ORF1ab/nsp16143N143HAatCat1303All0
ORF1ab/nsp16143N143HAaTCaC9696AY.1030.000596
ORF1ab/nsp16143N143HAaTCaC3838AY.1200.001413
ORF1ab/nsp16143N143HAaTCaC3838AY.40.000059
ORF1ab/nsp16143N143HAaTCaC3435B.1.1.70.00003
ORF1ab/nsp16143N143HAatCat135B.1.1.70.000001
ORF1ab/nsp16143N143HAaTCaC2424B.1.177.40.005065
ORF1ab/nsp16143N143HAaTCaC2323AY.9.20.000845
ORF1ab/nsp16143N143HAaTCaC1111B.1.617.20.000041
ORF1ab/nsp16143N143HAaTCaC99B.1.1.440.021687
ORF1ab/nsp16143N143HAaTCaC66AY.430.000027
ORF1ab/nsp16143N143HAaTCaC55B.1.1770.000066
ORF1ab/nsp16143N143HAaTCaC22AY.3.10.000171
ORF1ab/nsp16143N143HAaTCaC22AY.460.000208
ORF1ab/nsp16143N143HAaTCaC22B.1.1600.000062
ORF1ab/nsp16143N143HAaTCaC22B.4.80.142857
ORF1ab/nsp16143N143HAaTCaC11A.23.10.000704
ORF1ab/nsp16143N143HAaTCaC11AY.260.000028
ORF1ab/nsp16143N143HAaTCaC11AY.30.00001
ORF1ab/nsp16143N143HAaTCaC11AY.440.000006
ORF1ab/nsp16143N143HAaTCaC11AY.50.000021
ORF1ab/nsp16143N143HAaTCaC11AY.60.000041
ORF1ab/nsp16143N143HAaTCaC11B.10.000009
ORF1ab/nsp16143N143HAaTCaC11B.1.1.1640.005155
ORF1ab/nsp16143N143HAaTCaC11B.1.1.3110.000358
ORF1ab/nsp16143N143HAaTCaC11B.1.177.190.001431

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.