CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = H225Q

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16225H225QH7023QnonsyncaTcaG20140.721331-21333
ORF1ab/nsp16225H225QH7023QnonsyncaTcaA2060.321331-21333

Details of the mutation H225Q within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16225H225QcaTcaG1420All0.000003
ORF1ab/nsp16225H225QcaTcaA620All0.000001
ORF1ab/nsp16225H225QcaTcaG45B.10.000037
ORF1ab/nsp16225H225QcaTcaA15B.10.000009
ORF1ab/nsp16225H225QcaTcaG12AY.260.000028
ORF1ab/nsp16225H225QcaTcaA12AY.260.000028
ORF1ab/nsp16225H225QcaTcaG22B.1.1.70.000002
ORF1ab/nsp16225H225QcaTcaG22B.1.20.000018
ORF1ab/nsp16225H225QcaTcaG22D.20.00015
ORF1ab/nsp16225H225QcaTcaG11AY.1030.000006
ORF1ab/nsp16225H225QcaTcaA11B.1.1.2740.005051
ORF1ab/nsp16225H225QcaTcaA11B.1.1600.000031
ORF1ab/nsp16225H225QcaTcaA11B.1.2210.000071
ORF1ab/nsp16225H225QcaTcaA11B.1.4290.000024
ORF1ab/nsp16225H225QcaTcaG11B.1.6060.006024
ORF1ab/nsp16225H225QcaTcaG11B.1.617.20.000004

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.