CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = D133Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16133D133YD6931YnonsynGacTac2727121055-21057

Details of the mutation D133Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16133D133YGacTac2727All0.000005
ORF1ab/nsp16133D133YGacTac44AY.40.000006
ORF1ab/nsp16133D133YGacTac44B.10.000037
ORF1ab/nsp16133D133YGacTac33AY.430.000013
ORF1ab/nsp16133D133YGacTac33B.1.1.70.000003
ORF1ab/nsp16133D133YGacTac22B.1.20.000018
ORF1ab/nsp16133D133YGacTac11A0.000387
ORF1ab/nsp16133D133YGacTac11AY.520.000814
ORF1ab/nsp16133D133YGacTac11B0.000128
ORF1ab/nsp16133D133YGacTac11B.1.1.1890.001513
ORF1ab/nsp16133D133YGacTac11B.1.2430.00007
ORF1ab/nsp16133D133YGacTac11B.1.3010.005917
ORF1ab/nsp16133D133YGacTac11B.1.6120.002653
ORF1ab/nsp16133D133YGacTac11B.1.6230.000536
ORF1ab/nsp16133D133YGacTac11B.1.6370.000073
ORF1ab/nsp16133D133YGacTac11C.300.001727
ORF1ab/nsp16133D133YGacTac11D.20.000075

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.