CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = A188S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16188A188SA6986SnonsynGcaTca563456330.99982221220-21222
ORF1ab/nsp16188A188SA6986SnonsynGcATcC563410.00017749421220-21222

Details of the mutation A188S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16188A188SGcaTca56335634All0.001077
ORF1ab/nsp16188A188SGcATcC15634All0
ORF1ab/nsp16188A188SGcaTca23282328AY.40.003623
ORF1ab/nsp16188A188SGcaTca609609B.1.1.70.000545
ORF1ab/nsp16188A188SGcaTca327327AW.10.996951
ORF1ab/nsp16188A188SGcaTca300300AY.440.001826
ORF1ab/nsp16188A188SGcaTca266266B.1.617.20.001002
ORF1ab/nsp16188A188SGcaTca193193AY.430.000855
ORF1ab/nsp16188A188SGcaTca127127B.1.1770.001672
ORF1ab/nsp16188A188SGcaTca9393B.1.20.000819
ORF1ab/nsp16188A188SGcaTca8686AY.980.006794
ORF1ab/nsp16188A188SGcaTca8181AY.1030.000503
ORF1ab/nsp16188A188SGcaTca7777AY.50.00159
ORF1ab/nsp16188A188SGcaTca7171B.1.177.860.013025
ORF1ab/nsp16188A188SGcaTca6868AY.1020.001803
ORF1ab/nsp16188A188SGcaTca6363B.1.1600.001965
ORF1ab/nsp16188A188SGcaTca6363B.1.4040.082031
ORF1ab/nsp16188A188SGcaTca5555B.1.2210.003907
ORF1ab/nsp16188A188SGcaTca5353C.350.041022
ORF1ab/nsp16188A188SGcaTca4848B.1.1.3720.033058
ORF1ab/nsp16188A188SGcaTca4444B.10.000403
ORF1ab/nsp16188A188SGcaTca4343B.1.3110.011807
ORF1ab/nsp16188A188SGcaTca2626AY.340.002521
ORF1ab/nsp16188A188SGcaTca2424AY.46.10.024641
ORF1ab/nsp16188A188SGcaTca2323AY.200.000894
ORF1ab/nsp16188A188SGcaTca2222AY.90.001487
ORF1ab/nsp16188A188SGcaTca1919AY.250.000114
ORF1ab/nsp16188A188SGcaTca1919AY.390.00047
ORF1ab/nsp16188A188SGcaTca1919B.1.177.610.826087
ORF1ab/nsp16188A188SGcaTca1818AY.220.037657
ORF1ab/nsp16188A188SGcaTca1818AY.4.20.00039
ORF1ab/nsp16188A188SGcaTca1616AY.290.000252
ORF1ab/nsp16188A188SGcaTca1616B.1.10.00029
ORF1ab/nsp16188A188SGcaTca1515B.1.177.530.035885
ORF1ab/nsp16188A188SGcaTca1515B.1.2580.000998
ORF1ab/nsp16188A188SGcaTca1313P.10.000205
ORF1ab/nsp16188A188SGcaTca1212AY.39.10.000475
ORF1ab/nsp16188A188SGcaTca1212B.1.3510.000357
ORF1ab/nsp16188A188SGcaTca1212B.1.36.290.006208
ORF1ab/nsp16188A188SGcaTca1111B.1.1.5190.000437
ORF1ab/nsp16188A188SGcaTca1010AY.4.50.001075
ORF1ab/nsp16188A188SGcaTca1010B.1.1.4640.014728
ORF1ab/nsp16188A188SGcaTca99AY.30.00009
ORF1ab/nsp16188A188SGcaTca99AY.760.043478
ORF1ab/nsp16188A188SGcaTca89AY.9.20.000294
ORF1ab/nsp16188A188SGcATcC19AY.9.20.000037
ORF1ab/nsp16188A188SGcaTca99B.1.3460.011796
ORF1ab/nsp16188A188SGcaTca88B.1.1.3060.003507
ORF1ab/nsp16188A188SGcaTca88B.1.1.3170.003294
ORF1ab/nsp16188A188SGcaTca88B.1.177.40.001688
ORF1ab/nsp16188A188SGcaTca88B.1.2430.000557
ORF1ab/nsp16188A188SGcaTca88B.1.4800.0199
ORF1ab/nsp16188A188SGcaTca77AY.330.000467
ORF1ab/nsp16188A188SGcaTca77B.1.360.001021
ORF1ab/nsp16188A188SGcaTca77C.270.12963
ORF1ab/nsp16188A188SGcaTca77P.20.001306
ORF1ab/nsp16188A188SGcaTca66AY.1000.000276
ORF1ab/nsp16188A188SGcaTca66AY.260.00017
ORF1ab/nsp16188A188SGcaTca66D.20.00045
ORF1ab/nsp16188A188SGcaTca66R.10.00054
ORF1ab/nsp16188A188SGcaTca55AY.540.000477
ORF1ab/nsp16188A188SGcaTca55AY.60.000206
ORF1ab/nsp16188A188SGcaTca55B.1.6200.00473
ORF1ab/nsp16188A188SGcaTca44AY.1060.00134
ORF1ab/nsp16188A188SGcaTca44AY.1180.000251
ORF1ab/nsp16188A188SGcaTca44AY.230.000279
ORF1ab/nsp16188A188SGcaTca44AY.360.000593
ORF1ab/nsp16188A188SGcaTca44AY.450.000487
ORF1ab/nsp16188A188SGcaTca44AY.460.000416
ORF1ab/nsp16188A188SGcaTca44AY.46.60.000289
ORF1ab/nsp16188A188SGcaTca44AY.700.000834
ORF1ab/nsp16188A188SGcaTca44AY.850.001709
ORF1ab/nsp16188A188SGcaTca44AY.890.019608
ORF1ab/nsp16188A188SGcaTca33AY.1210.000406
ORF1ab/nsp16188A188SGcaTca33AY.20.001068
ORF1ab/nsp16188A188SGcaTca33AY.300.001187
ORF1ab/nsp16188A188SGcaTca33AY.420.000121
ORF1ab/nsp16188A188SGcaTca33AY.530.000863
ORF1ab/nsp16188A188SGcaTca33AY.630.001161
ORF1ab/nsp16188A188SGcaTca33AY.920.000862
ORF1ab/nsp16188A188SGcaTca33B.1.1.2160.002671
ORF1ab/nsp16188A188SGcaTca33B.1.1.2360.02069
ORF1ab/nsp16188A188SGcaTca33B.1.36.100.014354
ORF1ab/nsp16188A188SGcaTca33B.1.5260.000071
ORF1ab/nsp16188A188SGcaTca22AY.10.000791
ORF1ab/nsp16188A188SGcaTca22AY.46.20.001271
ORF1ab/nsp16188A188SGcaTca22AY.470.000062
ORF1ab/nsp16188A188SGcaTca22AY.610.00021
ORF1ab/nsp16188A188SGcaTca22AY.780.003082
ORF1ab/nsp16188A188SGcaTca22AY.98.10.000097
ORF1ab/nsp16188A188SGcaTca22AZ.20.001642
ORF1ab/nsp16188A188SGcaTca22B.1.1.1480.017544
ORF1ab/nsp16188A188SGcaTca22B.1.1.1980.002937
ORF1ab/nsp16188A188SGcaTca22B.1.1.2220.000408
ORF1ab/nsp16188A188SGcaTca22B.1.1.4320.002532
ORF1ab/nsp16188A188SGcaTca22B.1.110.30.001437
ORF1ab/nsp16188A188SGcaTca22B.1.1660.016949
ORF1ab/nsp16188A188SGcaTca22B.1.177.730.001133
ORF1ab/nsp16188A188SGcaTca22B.1.4290.000047
ORF1ab/nsp16188A188SGcaTca22B.1.617.10.000258
ORF1ab/nsp16188A188SGcaTca22P.1.140.000096
ORF1ab/nsp16188A188SGcaTca22P.1.17.10.00175
ORF1ab/nsp16188A188SGcaTca11A.2.50.000499
ORF1ab/nsp16188A188SGcaTca11A.23.10.000704
ORF1ab/nsp16188A188SGcaTca11A.250.018182
ORF1ab/nsp16188A188SGcaTca11AL.10.012987
ORF1ab/nsp16188A188SGcaTca11AY.1050.000643
ORF1ab/nsp16188A188SGcaTca11AY.1100.000113
ORF1ab/nsp16188A188SGcaTca11AY.1140.000231
ORF1ab/nsp16188A188SGcaTca11AY.116.10.000311
ORF1ab/nsp16188A188SGcaTca11AY.1190.000035
ORF1ab/nsp16188A188SGcaTca11AY.1200.000037
ORF1ab/nsp16188A188SGcaTca11AY.140.000088
ORF1ab/nsp16188A188SGcaTca11AY.240.000431
ORF1ab/nsp16188A188SGcaTca11AY.3.10.000085
ORF1ab/nsp16188A188SGcaTca11AY.39.1.10.000725
ORF1ab/nsp16188A188SGcaTca11AY.4.30.000842
ORF1ab/nsp16188A188SGcaTca11AY.4.40.000409
ORF1ab/nsp16188A188SGcaTca11AY.46.50.000198
ORF1ab/nsp16188A188SGcaTca11AY.590.00053
ORF1ab/nsp16188A188SGcaTca11AY.7.10.000113
ORF1ab/nsp16188A188SGcaTca11AY.750.000056
ORF1ab/nsp16188A188SGcaTca11AY.99.20.000092
ORF1ab/nsp16188A188SGcaTca11B0.000128
ORF1ab/nsp16188A188SGcaTca11B.1.1.1700.001247
ORF1ab/nsp16188A188SGcaTca11B.1.1.2140.000055
ORF1ab/nsp16188A188SGcaTca11B.1.1.250.000569
ORF1ab/nsp16188A188SGcaTca11B.1.1.2860.002899
ORF1ab/nsp16188A188SGcaTca11B.1.1.700.000341
ORF1ab/nsp16188A188SGcaTca11B.1.1190.010526
ORF1ab/nsp16188A188SGcaTca11B.1.1590.012195
ORF1ab/nsp16188A188SGcaTca11B.1.177.430.001477
ORF1ab/nsp16188A188SGcaTca11B.1.177.70.000165
ORF1ab/nsp16188A188SGcaTca11B.1.177.830.001481
ORF1ab/nsp16188A188SGcaTca11B.1.2340.000132
ORF1ab/nsp16188A188SGcaTca11B.1.351.20.000303
ORF1ab/nsp16188A188SGcaTca11B.1.351.50.0006
ORF1ab/nsp16188A188SGcaTca11B.1.36.10.00114
ORF1ab/nsp16188A188SGcaTca11B.1.36.170.000494
ORF1ab/nsp16188A188SGcaTca11B.1.36.70.004
ORF1ab/nsp16188A188SGcaTca11B.1.3750.00082
ORF1ab/nsp16188A188SGcaTca11B.1.3970.004854
ORF1ab/nsp16188A188SGcaTca11B.1.4000.000429
ORF1ab/nsp16188A188SGcaTca11B.1.4160.001269
ORF1ab/nsp16188A188SGcaTca11B.1.4270.00005
ORF1ab/nsp16188A188SGcaTca11B.1.5090.000866
ORF1ab/nsp16188A188SGcaTca11B.1.5380.008065
ORF1ab/nsp16188A188SGcaTca11B.1.5640.000426
ORF1ab/nsp16188A188SGcaTca11B.1.810.021277
ORF1ab/nsp16188A188SGcaTca11B.1.9.30.038462
ORF1ab/nsp16188A188SGcaTca11B.6.60.000889
ORF1ab/nsp16188A188SGcaTca11C.370.000116
ORF1ab/nsp16188A188SGcaTca11L.30.003546
ORF1ab/nsp16188A188SGcaTca11P.1.120.000484
ORF1ab/nsp16188A188SGcaTca11P.30.001595
ORF1ab/nsp16188A188SGcaTca11P.70.004367
ORF1ab/nsp16188A188SGcaTca11Q.10.000126
ORF1ab/nsp16188A188SGcaTca11Q.40.000455
ORF1ab/nsp16188A188SGcaTca11U.10.012821

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.