CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = A188A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16188A188AA6986AsyngcAgcT690160920.88277121220-21222
ORF1ab/nsp16188A188AA6986AsyngcAgcG69017950.11520121220-21222
ORF1ab/nsp16188A188AA6986AsyngcAgcC6901140.0020286921220-21222

Details of the mutation A188A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16188A188AgcAgcT60926901All0.001165
ORF1ab/nsp16188A188AgcAgcG7956901All0.000152
ORF1ab/nsp16188A188AgcAgcC146901All0.000003
ORF1ab/nsp16188A188AgcAgcT49964996B.1.177.810.945854
ORF1ab/nsp16188A188AgcAgcT488489B.1.1770.006426
ORF1ab/nsp16188A188AgcAgcG1489B.1.1770.000013
ORF1ab/nsp16188A188AgcAgcT339339Z.10.979769
ORF1ab/nsp16188A188AgcAgcT199199B.1.177.500.934272
ORF1ab/nsp16188A188AgcAgcG162162AY.40.000252
ORF1ab/nsp16188A188AgcAgcG141143B.1.617.20.000531
ORF1ab/nsp16188A188AgcAgcC2143B.1.617.20.000008
ORF1ab/nsp16188A188AgcAgcG106106B.1.2340.013986
ORF1ab/nsp16188A188AgcAgcG9698AY.440.000584
ORF1ab/nsp16188A188AgcAgcT298AY.440.000012
ORF1ab/nsp16188A188AgcAgcG9394AY.430.000412
ORF1ab/nsp16188A188AgcAgcC194AY.430.000004
ORF1ab/nsp16188A188AgcAgcG2835B.1.1.70.000025
ORF1ab/nsp16188A188AgcAgcC435B.1.1.70.000004
ORF1ab/nsp16188A188AgcAgcT335B.1.1.70.000003
ORF1ab/nsp16188A188AgcAgcT1119B.10.000101
ORF1ab/nsp16188A188AgcAgcG819B.10.000073
ORF1ab/nsp16188A188AgcAgcG1616AY.34.10.008159
ORF1ab/nsp16188A188AgcAgcG1414B.1.5610.005558
ORF1ab/nsp16188A188AgcAgcG1313AY.390.000321
ORF1ab/nsp16188A188AgcAgcT613B.1.10.000109
ORF1ab/nsp16188A188AgcAgcG513B.1.10.000091
ORF1ab/nsp16188A188AgcAgcC213B.1.10.000036
ORF1ab/nsp16188A188AgcAgcT911B.1.20.000079
ORF1ab/nsp16188A188AgcAgcG211B.1.20.000018
ORF1ab/nsp16188A188AgcAgcG710AY.30.00007
ORF1ab/nsp16188A188AgcAgcT310AY.30.00003
ORF1ab/nsp16188A188AgcAgcG1010AY.750.00056
ORF1ab/nsp16188A188AgcAgcG99AY.1030.000056
ORF1ab/nsp16188A188AgcAgcG88B.1.5390.140351
ORF1ab/nsp16188A188AgcAgcG77Q.70.007778
ORF1ab/nsp16188A188AgcAgcG66AY.250.000036
ORF1ab/nsp16188A188AgcAgcG66B.1.5250.000679
ORF1ab/nsp16188A188AgcAgcT44B.1.177.720.013559
ORF1ab/nsp16188A188AgcAgcT33AY.1170.000254
ORF1ab/nsp16188A188AgcAgcG33AY.230.000209
ORF1ab/nsp16188A188AgcAgcT33AY.330.0002
ORF1ab/nsp16188A188AgcAgcG33AY.4.20.000065
ORF1ab/nsp16188A188AgcAgcG33AY.770.003382
ORF1ab/nsp16188A188AgcAgcT33B0.000383
ORF1ab/nsp16188A188AgcAgcG33B.1.2580.0002
ORF1ab/nsp16188A188AgcAgcG33B.1.4290.000071
ORF1ab/nsp16188A188AgcAgcG33B.1.5240.004219
ORF1ab/nsp16188A188AgcAgcG13P.10.000016
ORF1ab/nsp16188A188AgcAgcT13P.10.000016
ORF1ab/nsp16188A188AgcAgcC13P.10.000016
ORF1ab/nsp16188A188AgcAgcT22AY.1200.000074
ORF1ab/nsp16188A188AgcAgcG22AY.4.50.000215
ORF1ab/nsp16188A188AgcAgcG22B.1.1420.005797
ORF1ab/nsp16188A188AgcAgcC12B.1.1600.000031
ORF1ab/nsp16188A188AgcAgcT12B.1.1600.000031
ORF1ab/nsp16188A188AgcAgcT22B.1.177.310.022989
ORF1ab/nsp16188A188AgcAgcG12B.1.177.860.000183
ORF1ab/nsp16188A188AgcAgcT12B.1.177.860.000183
ORF1ab/nsp16188A188AgcAgcG22C.370.000232
ORF1ab/nsp16188A188AgcAgcG22P.20.000373
ORF1ab/nsp16188A188AgcAgcG11AY.1130.000142
ORF1ab/nsp16188A188AgcAgcG11AY.1190.000035
ORF1ab/nsp16188A188AgcAgcG11AY.1210.000135
ORF1ab/nsp16188A188AgcAgcT11AY.270.000065
ORF1ab/nsp16188A188AgcAgcG11AY.290.000016
ORF1ab/nsp16188A188AgcAgcG11AY.300.000396
ORF1ab/nsp16188A188AgcAgcC11AY.39.10.00004
ORF1ab/nsp16188A188AgcAgcG11AY.470.000031
ORF1ab/nsp16188A188AgcAgcG11AY.50.000021
ORF1ab/nsp16188A188AgcAgcG11AY.5.40.000277
ORF1ab/nsp16188A188AgcAgcG11AY.740.000116
ORF1ab/nsp16188A188AgcAgcG11AY.9.20.000037
ORF1ab/nsp16188A188AgcAgcG11AY.920.000287
ORF1ab/nsp16188A188AgcAgcG11AY.99.20.000092
ORF1ab/nsp16188A188AgcAgcG11B.1.1.1940.00495
ORF1ab/nsp16188A188AgcAgcT11B.1.1.2220.000204
ORF1ab/nsp16188A188AgcAgcG11B.1.1.330.000421
ORF1ab/nsp16188A188AgcAgcT11B.1.1.3720.000689
ORF1ab/nsp16188A188AgcAgcG11B.1.1.4110.014706
ORF1ab/nsp16188A188AgcAgcG11B.1.1.5230.001563
ORF1ab/nsp16188A188AgcAgcG11B.1.1.700.000341
ORF1ab/nsp16188A188AgcAgcG11B.1.177.210.000076
ORF1ab/nsp16188A188AgcAgcT11B.1.177.350.000691
ORF1ab/nsp16188A188AgcAgcG11B.1.177.40.000211
ORF1ab/nsp16188A188AgcAgcT11B.1.177.650.000665
ORF1ab/nsp16188A188AgcAgcT11B.1.177.750.001041
ORF1ab/nsp16188A188AgcAgcT11B.1.177.760.002494
ORF1ab/nsp16188A188AgcAgcG11B.1.1950.005025
ORF1ab/nsp16188A188AgcAgcG11B.1.2210.000071
ORF1ab/nsp16188A188AgcAgcT11B.1.2400.000216
ORF1ab/nsp16188A188AgcAgcT11B.1.2430.00007
ORF1ab/nsp16188A188AgcAgcT11B.1.258.170.000104
ORF1ab/nsp16188A188AgcAgcT11B.1.258.210.007752
ORF1ab/nsp16188A188AgcAgcG11B.1.258.220.002667
ORF1ab/nsp16188A188AgcAgcT11B.1.3240.001605
ORF1ab/nsp16188A188AgcAgcT11B.1.3510.00003
ORF1ab/nsp16188A188AgcAgcG11B.1.360.000146
ORF1ab/nsp16188A188AgcAgcC11B.1.36.80.001
ORF1ab/nsp16188A188AgcAgcG11B.1.3750.00082
ORF1ab/nsp16188A188AgcAgcG11B.1.4560.003268
ORF1ab/nsp16188A188AgcAgcG11B.1.4590.004082
ORF1ab/nsp16188A188AgcAgcT11B.1.466.20.000391
ORF1ab/nsp16188A188AgcAgcT11B.1.5260.000024
ORF1ab/nsp16188A188AgcAgcG11B.1.595.40.007299
ORF1ab/nsp16188A188AgcAgcT11B.1.6090.000479
ORF1ab/nsp16188A188AgcAgcC11B.1.6370.000073
ORF1ab/nsp16188A188AgcAgcG11P.1.150.000232
ORF1ab/nsp16188A188AgcAgcG11P.1.20.001156

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.