CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : Mut = A116S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp16116A116SA6914SnonsynGcaTca566656590.99876521004-21006
ORF1ab/nsp16116A116SA6914SnonsynGcATcT566640.00070596521004-21006
ORF1ab/nsp16116A116SA6914SnonsynGcATcC566630.00052947421004-21006

Details of the mutation A116S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp16116A116SGcaTca56595666All0.001082
ORF1ab/nsp16116A116SGcATcT45666All0.000001
ORF1ab/nsp16116A116SGcATcC35666All0.000001
ORF1ab/nsp16116A116SGcaTca11851185AZ.20.972906
ORF1ab/nsp16116A116SGcaTca11501150AZ.10.997398
ORF1ab/nsp16116A116SGcaTca626626AZ.30.951368
ORF1ab/nsp16116A116SGcaTca526526B.1.1.70.000471
ORF1ab/nsp16116A116SGcaTca223223AY.40.000347
ORF1ab/nsp16116A116SGcaTca182182B.1.20.001603
ORF1ab/nsp16116A116SGcaTca176176B.1.617.20.000663
ORF1ab/nsp16116A116SGcaTca148148B.1.1.3180.044659
ORF1ab/nsp16116A116SGcaTca123123P.1.140.00588
ORF1ab/nsp16116A116SGcaTca122122AZ.2.10.99187
ORF1ab/nsp16116A116SGcaTca111111P.1.70.035441
ORF1ab/nsp16116A116SGcaTca9999AY.430.000439
ORF1ab/nsp16116A116SGcaTca9292AY.260.002605
ORF1ab/nsp16116A116SGcaTca9191B.1.5250.010298
ORF1ab/nsp16116A116SGcaTca8282AY.440.000499
ORF1ab/nsp16116A116SGcaTca6969AY.1030.000428
ORF1ab/nsp16116A116SGcaTca4747B.1.10.000853
ORF1ab/nsp16116A116SGcaTca4040B.10.000366
ORF1ab/nsp16116A116SGcaTca3636AY.1180.002255
ORF1ab/nsp16116A116SGcaTca3232AY.1020.000848
ORF1ab/nsp16116A116SGcaTca2525AY.250.00015
ORF1ab/nsp16116A116SGcaTca2323B.1.1600.000717
ORF1ab/nsp16116A116SGcaTca2121AU.20.050847
ORF1ab/nsp16116A116SGcaTca1818AY.200.0007
ORF1ab/nsp16116A116SGcaTca1818AY.290.000284
ORF1ab/nsp16116A116SGcaTca1515AY.750.00084
ORF1ab/nsp16116A116SGcaTca1515B.1.1.5190.000596
ORF1ab/nsp16116A116SGcaTca1414B0.001789
ORF1ab/nsp16116A116SGcaTca1313B.1.4290.000306
ORF1ab/nsp16116A116SGcaTca1212B.1.1770.000158
ORF1ab/nsp16116A116SGcaTca1111A.290.058511
ORF1ab/nsp16116A116SGcaTca1111AY.390.000272
ORF1ab/nsp16116A116SGcaTca1010AY.1000.00046
ORF1ab/nsp16116A116SGcaTca490.222222
ORF1ab/nsp16116A116SGcATcT390.166667
ORF1ab/nsp16116A116SGcATcC290.111111
ORF1ab/nsp16116A116SGcaTca99AY.1190.000318
ORF1ab/nsp16116A116SGcaTca99AY.330.000601
ORF1ab/nsp16116A116SGcaTca99B.1.160.260.021792
ORF1ab/nsp16116A116SGcaTca88B.1.3110.002197
ORF1ab/nsp16116A116SGcaTca88B.1.4270.000404
ORF1ab/nsp16116A116SGcaTca88B.1.6300.041885
ORF1ab/nsp16116A116SGcaTca77AY.120.002212
ORF1ab/nsp16116A116SGcaTca77C.140.030303
ORF1ab/nsp16116A116SGcaTca77P.10.00011
ORF1ab/nsp16116A116SGcaTca66AY.30.00006
ORF1ab/nsp16116A116SGcaTca66AY.4.20.00013
ORF1ab/nsp16116A116SGcaTca66B.1.1.2910.004454
ORF1ab/nsp16116A116SGcaTca66B.1.5260.000141
ORF1ab/nsp16116A116SGcaTca66B.1.5960.000523
ORF1ab/nsp16116A116SGcaTca66N.50.010601
ORF1ab/nsp16116A116SGcaTca55AY.120.10.001605
ORF1ab/nsp16116A116SGcaTca55AY.420.000201
ORF1ab/nsp16116A116SGcaTca55AY.470.000156
ORF1ab/nsp16116A116SGcaTca55AY.540.000477
ORF1ab/nsp16116A116SGcaTca55B.1.360.00073
ORF1ab/nsp16116A116SGcaTca44AY.1210.000541
ORF1ab/nsp16116A116SGcaTca44AY.140.000352
ORF1ab/nsp16116A116SGcaTca44AY.46.40.000658
ORF1ab/nsp16116A116SGcaTca44AY.9.20.000147
ORF1ab/nsp16116A116SGcaTca44AY.920.001149
ORF1ab/nsp16116A116SGcaTca44B.1.1.2840.00043
ORF1ab/nsp16116A116SGcaTca24B.1.2210.000142
ORF1ab/nsp16116A116SGcATcT14B.1.2210.000071
ORF1ab/nsp16116A116SGcATcC14B.1.2210.000071
ORF1ab/nsp16116A116SGcaTca44B.1.2340.000528
ORF1ab/nsp16116A116SGcaTca44B.1.2580.000266
ORF1ab/nsp16116A116SGcaTca44B.1.6210.000354
ORF1ab/nsp16116A116SGcaTca33AY.1080.003308
ORF1ab/nsp16116A116SGcaTca33AY.1170.000254
ORF1ab/nsp16116A116SGcaTca33AY.1200.000112
ORF1ab/nsp16116A116SGcaTca33AY.370.000948
ORF1ab/nsp16116A116SGcaTca33AY.4.50.000322
ORF1ab/nsp16116A116SGcaTca33AY.720.004082
ORF1ab/nsp16116A116SGcaTca33AY.90.000203
ORF1ab/nsp16116A116SGcaTca33B.1.1.3260.005282
ORF1ab/nsp16116A116SGcaTca33P.1.100.000808
ORF1ab/nsp16116A116SGcaTca22A.300.285714
ORF1ab/nsp16116A116SGcaTca22AY.230.000139
ORF1ab/nsp16116A116SGcaTca22AY.46.60.000144
ORF1ab/nsp16116A116SGcaTca22AY.550.001835
ORF1ab/nsp16116A116SGcaTca22AY.75.10.000361
ORF1ab/nsp16116A116SGcaTca22AY.9.10.000167
ORF1ab/nsp16116A116SGcaTca22B.1.1.2070.002364
ORF1ab/nsp16116A116SGcaTca22B.1.1.3170.000823
ORF1ab/nsp16116A116SGcaTca22B.1.1.330.000842
ORF1ab/nsp16116A116SGcaTca22B.1.1.3370.007194
ORF1ab/nsp16116A116SGcaTca22B.1.177.440.001038
ORF1ab/nsp16116A116SGcaTca22B.1.3510.000059
ORF1ab/nsp16116A116SGcaTca22C.160.002121
ORF1ab/nsp16116A116SGcaTca22C.370.000232
ORF1ab/nsp16116A116SGcaTca22C.380.016129
ORF1ab/nsp16116A116SGcaTca22D.20.00015
ORF1ab/nsp16116A116SGcaTca11A.10.000282
ORF1ab/nsp16116A116SGcaTca11A.280.002646
ORF1ab/nsp16116A116SGcaTca11AT.10.005128
ORF1ab/nsp16116A116SGcaTca11AY.1050.000643
ORF1ab/nsp16116A116SGcaTca11AY.1100.000113
ORF1ab/nsp16116A116SGcaTca11AY.1130.000142
ORF1ab/nsp16116A116SGcaTca11AY.120.2.10.000498
ORF1ab/nsp16116A116SGcaTca11AY.160.00038
ORF1ab/nsp16116A116SGcaTca11AY.23.10.000417
ORF1ab/nsp16116A116SGcaTca11AY.34.10.00051
ORF1ab/nsp16116A116SGcaTca11AY.350.000233
ORF1ab/nsp16116A116SGcaTca11AY.4.10.000737
ORF1ab/nsp16116A116SGcaTca11AY.410.000294
ORF1ab/nsp16116A116SGcaTca11AY.450.000122
ORF1ab/nsp16116A116SGcaTca11AY.460.000104
ORF1ab/nsp16116A116SGcaTca11AY.50.000021
ORF1ab/nsp16116A116SGcaTca11AY.5.20.002463
ORF1ab/nsp16116A116SGcaTca11AY.5.40.000277
ORF1ab/nsp16116A116SGcaTca11AY.530.000288
ORF1ab/nsp16116A116SGcaTca11AY.560.001605
ORF1ab/nsp16116A116SGcaTca11AY.740.000116
ORF1ab/nsp16116A116SGcaTca11AY.980.000079
ORF1ab/nsp16116A116SGcaTca11AY.98.10.000048
ORF1ab/nsp16116A116SGcaTca11B.1.1.10.000327
ORF1ab/nsp16116A116SGcaTca11B.1.1.1290.009174
ORF1ab/nsp16116A116SGcaTca11B.1.1.2160.00089
ORF1ab/nsp16116A116SGcaTca11B.1.1.280.000311
ORF1ab/nsp16116A116SGcaTca11B.1.1.3970.002252
ORF1ab/nsp16116A116SGcaTca11B.1.1470.000756
ORF1ab/nsp16116A116SGcaTca11B.1.160.300.002976
ORF1ab/nsp16116A116SGcaTca11B.1.160.330.004425
ORF1ab/nsp16116A116SGcaTca11B.1.177.170.000821
ORF1ab/nsp16116A116SGcaTca11B.1.177.210.000076
ORF1ab/nsp16116A116SGcaTca11B.1.177.40.000211
ORF1ab/nsp16116A116SGcaTca11B.1.177.530.002392
ORF1ab/nsp16116A116SGcaTca11B.1.2370.004975
ORF1ab/nsp16116A116SGcaTca11B.1.2430.00007
ORF1ab/nsp16116A116SGcaTca11B.1.2510.021739
ORF1ab/nsp16116A116SGcaTca11B.1.3060.005714
ORF1ab/nsp16116A116SGcaTca11B.1.36.290.000517
ORF1ab/nsp16116A116SGcaTca11B.1.36.80.001
ORF1ab/nsp16116A116SGcaTca11B.1.3960.000706
ORF1ab/nsp16116A116SGcaTca11B.1.466.20.000391
ORF1ab/nsp16116A116SGcaTca11B.1.5300.007143
ORF1ab/nsp16116A116SGcaTca11B.1.5430.01
ORF1ab/nsp16116A116SGcaTca11B.1.5600.00463
ORF1ab/nsp16116A116SGcaTca11B.1.5610.000397
ORF1ab/nsp16116A116SGcaTca11B.1.5650.00081
ORF1ab/nsp16116A116SGcaTca11B.1.5730.006098
ORF1ab/nsp16116A116SGcaTca11B.1.5760.000907
ORF1ab/nsp16116A116SGcaTca11B.1.5970.00463
ORF1ab/nsp16116A116SGcaTca11B.1.6030.010638
ORF1ab/nsp16116A116SGcaTca11B.1.617.10.000129
ORF1ab/nsp16116A116SGcaTca11B.1.6180.004032
ORF1ab/nsp16116A116SGcaTca11B.1.6200.000946
ORF1ab/nsp16116A116SGcaTca11P.1.160.000374
ORF1ab/nsp16116A116SGcaTca11P.1.80.004785
ORF1ab/nsp16116A116SGcaTca11Q.20.000613
ORF1ab/nsp16116A116SGcaTca11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.