CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp16 : CodonNum = 85

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp1685L85LL6883LsynTtaCta318130850.96982120911-20913
ORF1ab/nsp1685L85LL6883LsynttAttG3181940.029550520911-20913
ORF1ab/nsp1685L85LL6883LsynTtACtG318110.00031436720911-20913
ORF1ab/nsp1685L85LL6883LsynTtACtT318110.00031436720911-20913
ORF1ab/nsp1685L85delL6883deldelTTA---2323120911-20913
ORF1ab/nsp1685L85FL6883FnonsynttAttT21180.85714320911-20913
ORF1ab/nsp1685L85FL6883FnonsynttAttC2130.14285720911-20913
ORF1ab/nsp1685L85SL6883SnonsyntTatCa12110.91666720911-20913
ORF1ab/nsp1685L85SL6883SnonsyntTAtCC1210.083333320911-20913
ORF1ab/nsp1685L85XL6883XnonsyntTatAa960.66666720911-20913
ORF1ab/nsp1685L85XL6883XnonsyntTatGa920.22222220911-20913
ORF1ab/nsp1685L85XL6883XnonsyntTAtAG910.11111120911-20913
ORF1ab/nsp1685L85del1L6883del1delttAtt-420.520911-20913
ORF1ab/nsp1685L85del1L6883del1delTta-ta420.520911-20913
ORF1ab/nsp1685L85VL6883VnonsynTtaGta320.66666720911-20913
ORF1ab/nsp1685L85VL6883VnonsynTtAGtC310.33333320911-20913
ORF1ab/nsp1685L85IL6883InonsynTtaAta22120911-20913
ORF1ab/nsp1685L85AL6883AnonsynTTAGCC210.520911-20913
ORF1ab/nsp1685L85AL6883AnonsynTTaGCa210.520911-20913
ORF1ab/nsp1685L85PL6883PnonsynTTaCCa11120911-20913
ORF1ab/nsp1685L85KL6883KnonsynTTaAAa11120911-20913

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp1685L85LTtaCta30853181All0.00059
ORF1ab/nsp1685L85LttAttG943181All0.000018
ORF1ab/nsp1685L85LTtACtG13181All0
ORF1ab/nsp1685L85LTtACtT13181All0
ORF1ab/nsp1685L85LTtaCta28162819AY.370.890013
ORF1ab/nsp1685L85LttAttG32819AY.370.000948
ORF1ab/nsp1685L85LTtaCta103103B.1.617.20.000388
ORF1ab/nsp1685L85LTtaCta6668AY.40.000103
ORF1ab/nsp1685L85LttAttG268AY.40.000003
ORF1ab/nsp1685L85LttAttG3142B.1.1.70.000028
ORF1ab/nsp1685L85LTtaCta1142B.1.1.70.00001
ORF1ab/nsp1685L85delTTA---2323All0.000004
ORF1ab/nsp1685L85FttAttT1821All0.000003
ORF1ab/nsp1685L85FttAttC321All0.000001
ORF1ab/nsp1685L85LttAttG1213AY.250.000072
ORF1ab/nsp1685L85LTtaCta113AY.250.000006
ORF1ab/nsp1685L85StTatCa1112All0.000002
ORF1ab/nsp1685L85StTAtCC112All0
ORF1ab/nsp1685L85LttAttG1011AY.200.000389
ORF1ab/nsp1685L85LTtaCta111AY.200.000039
ORF1ab/nsp1685L85LTtaCta611AY.440.000037
ORF1ab/nsp1685L85LttAttG511AY.440.00003
ORF1ab/nsp1685L85XtTatAa69All0.000001
ORF1ab/nsp1685L85XtTatGa29All0
ORF1ab/nsp1685L85XtTAtAG19All0
ORF1ab/nsp1685L85LTtaCta99AY.130.001449
ORF1ab/nsp1685L85LTtaCta99AY.240.003879
ORF1ab/nsp1685L85LTtaCta99AY.430.00004
ORF1ab/nsp1685L85FttAttT99AY.850.003845
ORF1ab/nsp1685L85LTtaCta47B.10.000037
ORF1ab/nsp1685L85LttAttG37B.10.000027
ORF1ab/nsp1685L85delTTA---77B.1.1.70.000006
ORF1ab/nsp1685L85LttAttG36AY.1030.000019
ORF1ab/nsp1685L85LTtaCta36AY.1030.000019
ORF1ab/nsp1685L85LTtaCta55AY.390.000124
ORF1ab/nsp1685L85LTtaCta55AY.650.002665
ORF1ab/nsp1685L85LttAttG35B.1.20.000026
ORF1ab/nsp1685L85LTtaCta25B.1.20.000018
ORF1ab/nsp1685L85del1Tta-ta24All0
ORF1ab/nsp1685L85del1ttAtt-24All0
ORF1ab/nsp1685L85LTtaCta44AY.75.10.000721
ORF1ab/nsp1685L85LttAttG24B.1.1770.000026
ORF1ab/nsp1685L85LTtACtG14B.1.1770.000013
ORF1ab/nsp1685L85LTtaCta14B.1.1770.000013
ORF1ab/nsp1685L85VTtaGta23All0
ORF1ab/nsp1685L85VTtAGtC13All0
ORF1ab/nsp1685L85LttAttG33AY.1010.001471
ORF1ab/nsp1685L85LttAttG23AY.30.00002
ORF1ab/nsp1685L85LTtACtT13AY.30.00001
ORF1ab/nsp1685L85FttAttT33AY.300.001187
ORF1ab/nsp1685L85LTtaCta33AY.600.002814
ORF1ab/nsp1685L85LttAttG33AY.9.20.00011
ORF1ab/nsp1685L85delTTA---33P.1.150.000697
ORF1ab/nsp1685L85XtTatAa220.111111
ORF1ab/nsp1685L85delTTA---220.111111
ORF1ab/nsp1685L85StTatCa120.055556
ORF1ab/nsp1685L85StTAtCC120.055556
ORF1ab/nsp1685L85VTtAGtC120.055556
ORF1ab/nsp1685L85ATTAGCC120.055556
ORF1ab/nsp1685L85VTtaGta120.055556
ORF1ab/nsp1685L85ATTaGCa120.055556
ORF1ab/nsp1685L85ITtaAta22All0
ORF1ab/nsp1685L85ATTAGCC12All0
ORF1ab/nsp1685L85ATTaGCa12All0
ORF1ab/nsp1685L85LTtaCta22AY.1050.001286
ORF1ab/nsp1685L85LTtaCta12AY.1170.000085
ORF1ab/nsp1685L85LttAttG12AY.1170.000085
ORF1ab/nsp1685L85delTTA---22AY.1200.000074
ORF1ab/nsp1685L85LTtaCta22AY.16.10.00094
ORF1ab/nsp1685L85FttAttC12AY.250.000006
ORF1ab/nsp1685L85FttAttT12AY.250.000006
ORF1ab/nsp1685L85LTtaCta22AY.260.000057
ORF1ab/nsp1685L85FttAttT22AY.390.000049
ORF1ab/nsp1685L85LTtaCta22AY.460.000208
ORF1ab/nsp1685L85LttAttG22AY.470.000062
ORF1ab/nsp1685L85LttAttG22AY.530.000575
ORF1ab/nsp1685L85LTtaCta22AY.610.00021
ORF1ab/nsp1685L85LttAttG12B.1.1600.000031
ORF1ab/nsp1685L85LTtaCta12B.1.1600.000031
ORF1ab/nsp1685L85LTtaCta12B.1.2210.000071
ORF1ab/nsp1685L85LttAttG12B.1.2210.000071
ORF1ab/nsp1685L85FttAttC110.055556
ORF1ab/nsp1685L85LTtaCta11A.20.000662
ORF1ab/nsp1685L85PTTaCCa11All0
ORF1ab/nsp1685L85KTTaAAa11All0
ORF1ab/nsp1685L85XtTatGa11AY.1030.000006
ORF1ab/nsp1685L85LTtaCta11AY.1100.000113
ORF1ab/nsp1685L85FttAttT11AY.1190.000035
ORF1ab/nsp1685L85XtTatAa11AY.120.10.000321
ORF1ab/nsp1685L85ITtaAta11AY.1210.000135
ORF1ab/nsp1685L85delTTA---11AY.250.000006
ORF1ab/nsp1685L85LttAttG11AY.29.10.000221
ORF1ab/nsp1685L85StTatCa11AY.30.00001
ORF1ab/nsp1685L85LttAttG11AY.4.20.000022
ORF1ab/nsp1685L85delTTA---11AY.4.50.000107
ORF1ab/nsp1685L85StTatCa11AY.440.000006
ORF1ab/nsp1685L85del1ttAtt-11AY.440.000006
ORF1ab/nsp1685L85LTtaCta11AY.520.000814
ORF1ab/nsp1685L85LTtaCta11AY.540.000095
ORF1ab/nsp1685L85LTtaCta11AY.710.000475
ORF1ab/nsp1685L85LTtaCta11AY.740.000116
ORF1ab/nsp1685L85LTtaCta11AY.750.000056
ORF1ab/nsp1685L85delTTA---11AY.75.10.00018
ORF1ab/nsp1685L85FttAttT11AY.790.001211
ORF1ab/nsp1685L85LTtaCta11AY.90.000068
ORF1ab/nsp1685L85XtTAtAG11AY.9.20.000037
ORF1ab/nsp1685L85LTtaCta11B0.000128
ORF1ab/nsp1685L85XtTatAa11B.10.000009
ORF1ab/nsp1685L85StTatCa11B.10.000009
ORF1ab/nsp1685L85LttAttG11B.1.1.2220.000204
ORF1ab/nsp1685L85LTtaCta11B.1.1.4090.002833
ORF1ab/nsp1685L85StTatCa11B.1.1.70.000001
ORF1ab/nsp1685L85FttAttT11B.1.1.70.000001
ORF1ab/nsp1685L85del1ttAtt-11B.1.1.70.000001
ORF1ab/nsp1685L85XtTatAa11B.1.1.70.000001
ORF1ab/nsp1685L85KTTaAAa11B.1.1.70.000001
ORF1ab/nsp1685L85ITtaAta11B.1.1.70.000001
ORF1ab/nsp1685L85StTatCa11B.1.110.30.000718
ORF1ab/nsp1685L85delTTA---11B.1.1400.018868
ORF1ab/nsp1685L85delTTA---11B.1.1610.017241
ORF1ab/nsp1685L85StTatCa11B.1.1770.000013
ORF1ab/nsp1685L85delTTA---11B.1.177.620.001192
ORF1ab/nsp1685L85PTTaCCa11B.1.20.000009
ORF1ab/nsp1685L85StTatCa11B.1.20.000009
ORF1ab/nsp1685L85delTTA---11B.1.2580.000067
ORF1ab/nsp1685L85del1Tta-ta11B.1.258.160.001637
ORF1ab/nsp1685L85FttAttC11B.1.3320.003497
ORF1ab/nsp1685L85StTatCa11B.1.3510.00003
ORF1ab/nsp1685L85StTatCa11B.1.36.190.009259
ORF1ab/nsp1685L85XtTatAa11B.1.3750.00082
ORF1ab/nsp1685L85LTtaCta11B.1.3810.007812
ORF1ab/nsp1685L85LTtaCta11B.1.3990.001934
ORF1ab/nsp1685L85delTTA---11B.1.4000.000429
ORF1ab/nsp1685L85LttAttG11B.1.4270.00005
ORF1ab/nsp1685L85XtTatGa11B.1.4530.003236
ORF1ab/nsp1685L85LttAttG11B.1.4590.004082
ORF1ab/nsp1685L85LTtaCta11B.1.5510.00129
ORF1ab/nsp1685L85del1Tta-ta11B.1.617.20.000004
ORF1ab/nsp1685L85delTTA---11B.1.6200.000946
ORF1ab/nsp1685L85StTatCa11B.1.6210.000089
ORF1ab/nsp1685L85LTtaCta11D.20.000075
ORF1ab/nsp1685L85VTtaGta11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.